BR112017005089A2 - associação de um agente antimicrobiano e de um composto de fórmula i para sua utilização - Google Patents
associação de um agente antimicrobiano e de um composto de fórmula i para sua utilizaçãoInfo
- Publication number
- BR112017005089A2 BR112017005089A2 BR112017005089-7A BR112017005089A BR112017005089A2 BR 112017005089 A2 BR112017005089 A2 BR 112017005089A2 BR 112017005089 A BR112017005089 A BR 112017005089A BR 112017005089 A2 BR112017005089 A2 BR 112017005089A2
- Authority
- BR
- Brazil
- Prior art keywords
- compound
- antimicrobial agent
- strain
- formula
- combination
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 6
- 239000004599 antimicrobial Substances 0.000 title abstract 4
- 208000015181 infectious disease Diseases 0.000 abstract 2
- 230000000813 microbial effect Effects 0.000 abstract 2
- 244000052769 pathogen Species 0.000 abstract 1
- 230000001717 pathogenic effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/075—Ethers or acetals
- A61K31/085—Ethers or acetals having an ether linkage to aromatic ring nuclear carbon
- A61K31/09—Ethers or acetals having an ether linkage to aromatic ring nuclear carbon having two or more such linkages
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/351—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom not condensed with another ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4178—1,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
- A61K31/424—Oxazoles condensed with heterocyclic ring systems, e.g. clavulanic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/429—Thiazoles condensed with heterocyclic ring systems
- A61K31/43—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/65—Tetracyclines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
- A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
- A61K31/7036—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin having at least one amino group directly attached to the carbocyclic ring, e.g. streptomycin, gentamycin, amikacin, validamycin, fortimicins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
a invenção tem como objeto um agente antimicrobiano potencializado para sua utilização no tratamento de uma infecção microbiana, distinguido pelo fato de que se utiliza em associação com o agente antimicrobiano um composto que corresponde à seguinte fórmula i: (i) em uma razão mássica, composto de fórmula (i):agente antimicrobiano, que varia de 8:1 a 1:10 e em que a infecção microbiana é induzida nomeadamente por um patógeno de estirpe a e que, nessa estirpe a, a concentração de composto (i) corresponde à seguinte equação: [c] < [cmi] / x, em que [c] é a concentração de acordo com a invenção de composto (i) a ser utilizada na estirpe a, [cmi] é a cmi medida para o composto (i), sozinho, nessa estirpe a, x é superior ou igual a 100, vantajosamente a 1.000, mais vantajosamente x está compreendido entre 2.000 e 10.000, ou superior a 50.000.
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR1458663 | 2014-09-15 | ||
FR1458663A FR3025719A1 (fr) | 2014-09-15 | 2014-09-15 | Antimicrobiens potentialises |
FR1462136A FR3025720B1 (fr) | 2014-09-15 | 2014-12-09 | Antimicrobiens potentialises |
FR1462136 | 2014-12-09 | ||
PCT/EP2015/071093 WO2016041958A1 (fr) | 2014-09-15 | 2015-09-15 | Antimicrobiens potentialises |
Publications (2)
Publication Number | Publication Date |
---|---|
BR112017005089A2 true BR112017005089A2 (pt) | 2018-01-23 |
BR112017005089B1 BR112017005089B1 (pt) | 2023-01-10 |
Family
ID=52130381
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112017005089-7A BR112017005089B1 (pt) | 2014-09-15 | 2015-09-15 | Uso de uma associação de um agente antimicrobiano e de um composto, e associação de um agente antimicrobiano e de cineol |
Country Status (7)
Country | Link |
---|---|
US (1) | US10668043B2 (pt) |
EP (1) | EP3193936B1 (pt) |
CN (1) | CN107073124B (pt) |
BR (1) | BR112017005089B1 (pt) |
DK (1) | DK3193936T3 (pt) |
FR (2) | FR3025719A1 (pt) |
WO (1) | WO2016041958A1 (pt) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR3048612B1 (fr) | 2016-03-14 | 2020-10-02 | Septeos | Tulathromycine potentialisee |
US11872216B2 (en) | 2016-06-02 | 2024-01-16 | Advanced Scientific Developments | Pharmaceutical formulation comprising cineole and amoxicillin |
FR3052066B1 (fr) * | 2016-06-02 | 2019-09-13 | Advanced Scientific Developements | Formulation pharmaceutique de cineol et d'amoxicilline |
FR3052065B1 (fr) * | 2016-06-02 | 2019-11-22 | Advanced Scientific Developements | Combinaison de cineol et d'amoxicilline pour une utilisation dans le traitement d'une infection bacterienne |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3787566A (en) * | 1969-07-29 | 1974-01-22 | Holliston Labor Inc | Disinfecting aerosol compositions |
US6319958B1 (en) | 1998-06-22 | 2001-11-20 | Wisconsin Alumni Research Foundation | Method of sensitizing microbial cells to antimicrobial compound |
US7258878B2 (en) * | 2004-12-20 | 2007-08-21 | Kimberly-Clark Worldwide, Inc. | Anti-microbial composition and methods of use thereof |
WO2006120494A1 (fr) | 2005-05-13 | 2006-11-16 | Advanced Scientific Developements | Combinaison pharmaceutique comprenant un antibacterien et une substance active choisie parmi le carveol, le thymol, l’eugenol, le borneol et les carvacrol |
JP6415052B2 (ja) * | 2010-12-09 | 2018-10-31 | セプテオス | トランス−シンナムアルデヒドを含む医薬組成物、および感染治療におけるその使用 |
WO2012076718A1 (en) * | 2010-12-09 | 2012-06-14 | Societe De Developpement Scientifique - Sds | Anti-microbial composition |
-
2014
- 2014-09-15 FR FR1458663A patent/FR3025719A1/fr active Pending
- 2014-12-09 FR FR1462136A patent/FR3025720B1/fr active Active
-
2015
- 2015-09-15 DK DK15766125.7T patent/DK3193936T3/da active
- 2015-09-15 WO PCT/EP2015/071093 patent/WO2016041958A1/fr active Application Filing
- 2015-09-15 EP EP15766125.7A patent/EP3193936B1/fr active Active
- 2015-09-15 US US15/510,988 patent/US10668043B2/en not_active Expired - Fee Related
- 2015-09-15 BR BR112017005089-7A patent/BR112017005089B1/pt active IP Right Grant
- 2015-09-15 CN CN201580055896.6A patent/CN107073124B/zh active Active
Also Published As
Publication number | Publication date |
---|---|
FR3025719A1 (fr) | 2016-03-18 |
EP3193936A1 (fr) | 2017-07-26 |
US20180021296A1 (en) | 2018-01-25 |
FR3025720A1 (fr) | 2016-03-18 |
DK3193936T3 (da) | 2020-09-21 |
US10668043B2 (en) | 2020-06-02 |
WO2016041958A1 (fr) | 2016-03-24 |
CN107073124A (zh) | 2017-08-18 |
CN107073124B (zh) | 2020-10-13 |
FR3025720B1 (fr) | 2018-11-09 |
EP3193936B1 (fr) | 2020-06-17 |
BR112017005089B1 (pt) | 2023-01-10 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
MA41013A (fr) | Compositions comprenant des souches bactériennes | |
BR112017022021A2 (pt) | aplicação de agente anticaspa solúvel em tensoativo | |
BR112017005840A2 (pt) | processos para preparar uma solução aquosa de acrilamida, reduzir concentração de ácido acrílico de uma solução aquosa de acrilamida, solução aquosa de acrilamida, homopolímero ou copolímero de acrilamida, e, solução de um homopolímero e/ou copolímero de acrilamida. | |
BR112016002233A2 (pt) | composições de adoçante | |
BR112017002370A2 (pt) | indóis para uso na infecção pelo vírus da gripe | |
BR112017004524A2 (pt) | pirrolopirimidinas para uso na infecção pelo vírus da gripe | |
MY165124A (en) | Semifluorinated alkane compositions | |
CO2017013065A2 (es) | Moduladores de diaciglicerol aciltransferasa 2 (dgat2) | |
BR112017006671A2 (pt) | composição essencialmente livre de água e que compreende pelo menos um esporo que forma agente de controle biológico fúngico, um poliéter de trisiloxano modificado e sílica fumigada ou precipitada. | |
BR112015021352A2 (pt) | composições antimicrobianas | |
MA35920B1 (fr) | Composés destinés au traitement de l'amyotrophie spinale | |
BR112015027704A2 (pt) | Composto, uso do mesmo e composição farmacêutica antibacteriana | |
EA201591743A8 (ru) | СТИМУЛЯТОРЫ sGC | |
WO2015003816A3 (en) | Cystobactamides | |
BR112016029465A2 (pt) | chapa de aço elétrica | |
BR112018014794A2 (pt) | pirimidinas substituídas com arila para uso em infecção pelo vírus influenza | |
BR112017005089A2 (pt) | associação de um agente antimicrobiano e de um composto de fórmula i para sua utilização | |
BR112016013194A2 (pt) | Composições de higiene oral compreendendo carbonato de cálcio e sílica | |
BR112016006428A2 (pt) | anticorpo, fragmento de ligação a antígeno do anticorpo, composição farmacêutica, métodos para tratamento e/ou profilaxia de infecção por pseudomona e para produzir um anticorpo, agente de diagnóstico para infecção por pseudomona, kit de detecção para pseudomonas aeruginosa, polinucleotídeo, vetor, e, célula hospedeira transformada | |
BR112016016853A2 (pt) | Compostos contendo nitrogênio, seu uso e seu processo de preparação, composição farmacêutica e seu uso | |
BR112015023387A2 (pt) | composições lipídicas de racecodotril | |
MX352814B (es) | Composiciones para el cuidado oral que comprenden carbonato de calcio y talco. | |
BR112014030025A2 (pt) | composições de polissacarídeo e métodos de uso | |
CR20150417A (es) | Compuestos de azetidiniloxifenilpirrolidina | |
AU2013408771A8 (en) | Prebiotic oral care compositions containing an alkyl glycoside |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] |
Free format text: DE ACORDO COM O ARTIGO 229-C DA LEI NO 10196/2001, QUE MODIFICOU A LEI NO 9279/96, A CONCESSAO DA PATENTE ESTA CONDICIONADA A ANUENCIA PREVIA DA ANVISA. CONSIDERANDO A APROVACAO DOS TERMOS DO PARECER NO 337/PGF/EA/2010, BEM COMO A PORTARIA INTERMINISTERIAL NO 1065 DE 24/05/2012, ENCAMINHA-SE O PRESENTE PEDIDO PARA AS PROVIDENCIAS CABIVEIS. |
|
B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] | ||
B06U | Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette] | ||
B06A | Patent application procedure suspended [chapter 6.1 patent gazette] | ||
B09A | Decision: intention to grant [chapter 9.1 patent gazette] | ||
B16A | Patent or certificate of addition of invention granted [chapter 16.1 patent gazette] |
Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 15/09/2015, OBSERVADAS AS CONDICOES LEGAIS |