BR112017002535A2 - dispositivo de análise de fluxo lateral com controle de fluxo de filtração - Google Patents

dispositivo de análise de fluxo lateral com controle de fluxo de filtração

Info

Publication number
BR112017002535A2
BR112017002535A2 BR112017002535A BR112017002535A BR112017002535A2 BR 112017002535 A2 BR112017002535 A2 BR 112017002535A2 BR 112017002535 A BR112017002535 A BR 112017002535A BR 112017002535 A BR112017002535 A BR 112017002535A BR 112017002535 A2 BR112017002535 A2 BR 112017002535A2
Authority
BR
Brazil
Prior art keywords
filter
substrate
analysis device
sample addition
addition zone
Prior art date
Application number
BR112017002535A
Other languages
English (en)
Inventor
Zhong Ding
Philip C Hosimer
Edward R Scalice
Original Assignee
Ortho Clinical Diagnostics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ortho Clinical Diagnostics Inc filed Critical Ortho Clinical Diagnostics Inc
Publication of BR112017002535A2 publication Critical patent/BR112017002535A2/pt

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5023—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures with a sample being transported to, and subsequently stored in an absorbent for analysis
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/558—Immunoassay; Biospecific binding assay; Materials therefor using diffusion or migration of antigen or antibody
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54386—Analytical elements
    • G01N33/54387—Immunochromatographic test strips
    • G01N33/54388—Immunochromatographic test strips based on lateral flow
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0681—Filter
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0406—Moving fluids with specific forces or mechanical means specific forces capillary forces

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

"dispositivo de análise de fluxo lateral com controle de fluxo de filtração", por trar a presente invenção de um dispositivo de análise de fluxo lateral que inclui um substrato com uma zona de adição de amostra e uma trajetória de fluxo de fluido. uma cobertura suporta um filtro que tem uma porção que faz contato com o substrato para criar uma área de contato que ao menos parcialmente se sobrepõe à zona de adição de amostra. outra porção se estende a partir da porção de contato até a periferia suportada do filtro, para definir com o substrato um reservatório configurado para reter o filtrado por pressão capilar entre o substrato e a porção que se estende do filtro. o volume do reservatório se baseia em um ângulo agudo formado entre o substrato e a porção que se estende do filtro e em um menisco de fluido do filtrado. o filtro e a zona de adição de amostra são configurados para fornecer pressão capilar que drena o filtrado do reservatório para a zona de adição de amostra. métodos para controlar as características do fluxo em um dispositivo de análise de fluxo lateral são também descritos.
BR112017002535A 2014-08-08 2015-08-05 dispositivo de análise de fluxo lateral com controle de fluxo de filtração BR112017002535A2 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462034830P 2014-08-08 2014-08-08
US14/817,946 US11033896B2 (en) 2014-08-08 2015-08-04 Lateral-flow assay device with filtration flow control
PCT/US2015/043769 WO2016022655A1 (en) 2014-08-08 2015-08-05 Lateral-flow assay device with filtration flow control

Publications (1)

Publication Number Publication Date
BR112017002535A2 true BR112017002535A2 (pt) 2017-12-05

Family

ID=53835544

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112017002535A BR112017002535A2 (pt) 2014-08-08 2015-08-05 dispositivo de análise de fluxo lateral com controle de fluxo de filtração

Country Status (7)

Country Link
US (2) US11033896B2 (pt)
EP (1) EP3177928B1 (pt)
JP (1) JP6199527B1 (pt)
CN (1) CN106796232B (pt)
BR (1) BR112017002535A2 (pt)
CA (1) CA2957728C (pt)
WO (1) WO2016022655A1 (pt)

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EP3717910A4 (en) * 2017-11-28 2021-12-15 Bio-Rad Laboratories, Inc. LATERAL FLOW TEST DEVICE
US20210364503A1 (en) * 2018-02-02 2021-11-25 Nippon Chemiphar Co., Ltd. Biochemical reaction substrate and analyzer
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EP3771908A1 (en) 2019-07-29 2021-02-03 Fundació Institut Català de Nanociència i Nanotecnologia (ICN2) Lateral-electrophoretic bioassay
EP4060017B1 (en) * 2019-11-13 2024-01-17 BOE Technology Group Co., Ltd. Assay chip

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Also Published As

Publication number Publication date
EP3177928A1 (en) 2017-06-14
US20210268496A1 (en) 2021-09-02
CN106796232B (zh) 2018-06-26
JP2017530339A (ja) 2017-10-12
CN106796232A (zh) 2017-05-31
EP3177928B1 (en) 2018-01-03
WO2016022655A1 (en) 2016-02-11
CA2957728C (en) 2018-11-20
US20160038937A1 (en) 2016-02-11
JP6199527B1 (ja) 2017-09-20
CA2957728A1 (en) 2016-02-11
US11033896B2 (en) 2021-06-15

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Legal Events

Date Code Title Description
B11A Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing
B11Y Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette]