BR112017002535A2 - dispositivo de análise de fluxo lateral com controle de fluxo de filtração - Google Patents

dispositivo de análise de fluxo lateral com controle de fluxo de filtração

Info

Publication number
BR112017002535A2
BR112017002535A2 BR112017002535A BR112017002535A BR112017002535A2 BR 112017002535 A2 BR112017002535 A2 BR 112017002535A2 BR 112017002535 A BR112017002535 A BR 112017002535A BR 112017002535 A BR112017002535 A BR 112017002535A BR 112017002535 A2 BR112017002535 A2 BR 112017002535A2
Authority
BR
Brazil
Prior art keywords
filter
substrate
analysis device
sample addition
addition zone
Prior art date
Application number
BR112017002535A
Other languages
English (en)
Inventor
Zhong Ding
Philip C Hosimer
Edward R Scalice
Original Assignee
Ortho Clinical Diagnostics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ortho Clinical Diagnostics Inc filed Critical Ortho Clinical Diagnostics Inc
Publication of BR112017002535A2 publication Critical patent/BR112017002535A2/pt

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5023Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures with a sample being transported to, and subsequently stored in an absorbent for analysis
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/558Immunoassay; Biospecific binding assay; Materials therefor using diffusion or migration of antigen or antibody
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366Apparatus specially adapted for solid-phase testing
    • G01N33/54386Analytical elements
    • G01N33/54387Immunochromatographic test strips
    • G01N33/54388Immunochromatographic test strips based on lateral flow
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/06Auxiliary integrated devices, integrated components
    • B01L2300/0681Filter
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/04Moving fluids with specific forces or mechanical means
    • B01L2400/0403Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0406Moving fluids with specific forces or mechanical means specific forces capillary forces

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

"dispositivo de análise de fluxo lateral com controle de fluxo de filtração", por trar a presente invenção de um dispositivo de análise de fluxo lateral que inclui um substrato com uma zona de adição de amostra e uma trajetória de fluxo de fluido. uma cobertura suporta um filtro que tem uma porção que faz contato com o substrato para criar uma área de contato que ao menos parcialmente se sobrepõe à zona de adição de amostra. outra porção se estende a partir da porção de contato até a periferia suportada do filtro, para definir com o substrato um reservatório configurado para reter o filtrado por pressão capilar entre o substrato e a porção que se estende do filtro. o volume do reservatório se baseia em um ângulo agudo formado entre o substrato e a porção que se estende do filtro e em um menisco de fluido do filtrado. o filtro e a zona de adição de amostra são configurados para fornecer pressão capilar que drena o filtrado do reservatório para a zona de adição de amostra. métodos para controlar as características do fluxo em um dispositivo de análise de fluxo lateral são também descritos.
BR112017002535A 2014-08-08 2015-08-05 dispositivo de análise de fluxo lateral com controle de fluxo de filtração BR112017002535A2 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462034830P 2014-08-08 2014-08-08
US14/817,946 US11033896B2 (en) 2014-08-08 2015-08-04 Lateral-flow assay device with filtration flow control
PCT/US2015/043769 WO2016022655A1 (en) 2014-08-08 2015-08-05 Lateral-flow assay device with filtration flow control

Publications (1)

Publication Number Publication Date
BR112017002535A2 true BR112017002535A2 (pt) 2017-12-05

Family

ID=53835544

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112017002535A BR112017002535A2 (pt) 2014-08-08 2015-08-05 dispositivo de análise de fluxo lateral com controle de fluxo de filtração

Country Status (7)

Country Link
US (2) US11033896B2 (pt)
EP (1) EP3177928B1 (pt)
JP (1) JP6199527B1 (pt)
CN (1) CN106796232B (pt)
BR (1) BR112017002535A2 (pt)
CA (1) CA2957728C (pt)
WO (1) WO2016022655A1 (pt)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10073091B2 (en) 2014-08-08 2018-09-11 Ortho-Clinical Diagnostics, Inc. Lateral flow assay device
WO2016209147A1 (en) * 2015-06-20 2016-12-29 Roxhed Niclas A plasma separating microfluidic device
AU2017361281A1 (en) * 2016-11-18 2019-06-20 Kimberly-Clark Worldwide, Inc. Wettability-patterning method and designs for pumpless transport and precise manipulation of liquid volumes on and through porous materials
EP3717910A4 (en) * 2017-11-28 2021-12-15 Bio-Rad Laboratories, Inc. LATERAL FLOW TEST DEVICE
EP3748360A4 (en) * 2018-02-02 2021-11-03 Nippon Chemiphar Co., Ltd. BIOCHEMICAL REACTION SUBSTRATE AND ANALYSIS DEVICE
WO2019198178A1 (ja) * 2018-04-11 2019-10-17 株式会社島津製作所 フィールドフローフラクショネーション装置
EP3771908A1 (en) 2019-07-29 2021-02-03 Fundació Institut Català de Nanociència i Nanotecnologia (ICN2) Lateral-electrophoretic bioassay
US11986821B2 (en) * 2019-11-13 2024-05-21 Beijing Boe Health Technology Co., Ltd. Detection chip

Family Cites Families (60)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4287155A (en) 1980-06-16 1981-09-01 Eastman Kodak Company Sample tray and carrier for chemical analyzer
US4426451A (en) * 1981-01-28 1984-01-17 Eastman Kodak Company Multi-zoned reaction vessel having pressure-actuatable control means between zones
JPH0746107B2 (ja) 1987-04-27 1995-05-17 ユニリーバー・ナームローゼ・ベンノートシヤープ 検定法
US5120643A (en) 1987-07-13 1992-06-09 Abbott Laboratories Process for immunochromatography with colloidal particles
US4956302A (en) 1987-09-11 1990-09-11 Abbott Laboratories Lateral flow chromatographic binding assay device
AU2684488A (en) 1988-06-27 1990-01-04 Carter-Wallace, Inc. Test device and method for colored particle immunoassay
US5252496A (en) 1989-12-18 1993-10-12 Princeton Biomeditech Corporation Carbon black immunochemical label
US5607863A (en) 1991-05-29 1997-03-04 Smithkline Diagnostics, Inc. Barrier-controlled assay device
CN2264914Y (zh) 1994-09-03 1997-10-15 三明蓝波公司生物技术研究所 金标免疫斑点试剂盒
US6241886B1 (en) 1995-06-09 2001-06-05 Toyo Boseki Kabushiki Kaisha Plasma separation filter
US6391265B1 (en) 1996-08-26 2002-05-21 Biosite Diagnostics, Inc. Devices incorporating filters for filtering fluid samples
US5869004A (en) 1997-06-09 1999-02-09 Caliper Technologies Corp. Methods and apparatus for in situ concentration and/or dilution of materials in microfluidic systems
US6139800A (en) 1997-06-23 2000-10-31 Luminex Corporation Interlaced lasers for multiple fluorescence measurement
US6402300B1 (en) 1997-07-15 2002-06-11 Silverbrook Research Pty. Ltd. Ink jet nozzle assembly including meniscus pinning of a fluidic seal
US5876675A (en) 1997-08-05 1999-03-02 Caliper Technologies Corp. Microfluidic devices and systems
AUPP103497A0 (en) 1997-12-19 1998-01-15 Panbio Pty Ltd Assay apparatus
US6830731B1 (en) 1998-01-05 2004-12-14 Biosite, Inc. Immunoassay fluorometer
SE521415C2 (sv) 1998-02-17 2003-10-28 Hans Goeran Evald Martin Metod för att framställa en gassensortillhörig detektor, samt en detektor framställd enligt metoden
DE69911802T2 (de) 1998-10-14 2004-07-29 Gyros Ab Form und verfahren zu deren herstellung
US6918655B2 (en) 1998-10-16 2005-07-19 Silverbrook Research Pty Ltd Ink jet printhead with nozzles
US6270641B1 (en) 1999-04-26 2001-08-07 Sandia Corporation Method and apparatus for reducing sample dispersion in turns and junctions of microchannel systems
SE9903011D0 (sv) 1999-08-26 1999-08-26 Aamic Ab Sätt att framställa en plastprodukt och ett härför utnyttjat plastproduktformande arrangemang
ATE431859T1 (de) 1999-09-10 2009-06-15 Amic Ab Verfahren zur herstellung einer matrix
US6451264B1 (en) 2000-01-28 2002-09-17 Roche Diagnostics Corporation Fluid flow control in curved capillary channels
SE0001667D0 (sv) * 2000-05-05 2000-05-05 Pharmacia & Upjohn Diag Ab Assay device with timer function
US6896358B1 (en) 2000-05-24 2005-05-24 Silverbrook Research Pty Ltd Fluidic seal for an ink jet nozzle assembly
EP1292450B1 (en) 2000-05-24 2007-07-18 Silverbrook Research Pty. Limited Ink jet printhead nozzle array
GB2365526B (en) 2000-07-31 2003-12-03 Cambridge Life Sciences Assay apparatus for measuring the amount of an analyte in a biological or environmental sample
US6854825B1 (en) 2000-10-20 2005-02-15 Silverbrook Research Pty Ltd Printed media production
ATE336298T1 (de) 2000-10-25 2006-09-15 Boehringer Ingelheim Micropart Mikrostrukturierte plattform für die untersuchung einer flüssigkeit
US7312084B2 (en) 2001-07-13 2007-12-25 Ortho-Clinical Diagnostics, Inc. Tandem incubator for clinical analyzer
US7250303B2 (en) 2001-07-20 2007-07-31 Ortho-Clinical Diagnostics, Inc. Chemistry system for a clinical analyzer
US7205159B2 (en) * 2001-08-20 2007-04-17 Proteome Systems Intellectual Property Pty Ltd. Diagnostic testing process and apparatus
SE0201738D0 (sv) 2002-06-07 2002-06-07 Aamic Ab Micro-fluid structures
US7005301B2 (en) 2002-06-10 2006-02-28 Sandia National Laboratories Piecewise uniform conduction-like flow channels and method therefor
US7517694B2 (en) 2002-07-26 2009-04-14 Ortho-Clinical Diagnostics, Inc. Metering tip with internal features to control fluid meniscus and oscillation
AU2003278040A1 (en) 2002-10-24 2004-05-13 Spectral Diagnostics Inc. Diagnostic device
US7632468B2 (en) 2003-12-04 2009-12-15 Idexx Laboratories, Inc. Retaining clip for reagent test slides
US8043562B2 (en) 2003-12-08 2011-10-25 Ortho-Clinical Diagnostics, Inc. Analyzer having removable holders or a centrifuge
SE0400662D0 (sv) 2004-03-24 2004-03-24 Aamic Ab Assay device and method
US20060019265A1 (en) 2004-04-30 2006-01-26 Kimberly-Clark Worldwide, Inc. Transmission-based luminescent detection systems
SE527036C2 (sv) 2004-06-02 2005-12-13 Aamic Ab Analysanordning med reglerat flöde och motsvarande förfarande
DE102004031809B4 (de) 2004-07-01 2006-06-14 Carl Freudenberg Kg Filterelement und Filteranordnung
SE529254C2 (sv) 2005-06-17 2007-06-12 Aamic Ab Optiskt testsystem
SE0501418L (sv) 2005-06-20 2006-09-26 Aamic Ab Metod och medel för att åstadkomma vätsketransport
US7816122B2 (en) 2005-10-18 2010-10-19 Idexx Laboratories, Inc. Lateral flow device with onboard reagents
US20100176050A1 (en) 2005-11-24 2010-07-15 Bridgestone Corporation Fluid purifying apparatus and filter housing
SE529711C2 (sv) 2006-03-22 2007-11-06 Aamic Ab Fluorescensläsare
SE531948C2 (sv) 2006-06-20 2009-09-15 Aamic Ab Analysanordning för vätskeprover innefattande filter i direkt kontakt med projektioner
CA2654931C (en) * 2006-06-20 2015-05-19 Amic Ab Assay device and method with improved control functions
US7867768B2 (en) 2007-02-08 2011-01-11 Ortho-Clinical Diagnostics, Inc. Two dimensional sample handler
US7819507B2 (en) 2007-03-21 2010-10-26 Silverbrook Research Pty Ltd Printhead with meniscus anchor for controlled priming
US8470609B2 (en) 2007-09-11 2013-06-25 Jian Feng Chen Versatile drug testing device
JP5475692B2 (ja) 2008-02-27 2014-04-16 ベーリンガー インゲルハイム マイクロパーツ ゲゼルシャフト ミット ベシュレンクテル ハフツング 血漿の分離装置
WO2011131471A1 (de) 2010-04-23 2011-10-27 Boehringer Ingelheim Microparts Gmbh Vorrichtung zur plasmaseparation mittels einer zentralen kanalstruktur
CN103270150B (zh) 2010-10-25 2016-10-19 西托根有限公司 细胞采集装置
EP2836831B1 (en) 2012-04-11 2017-10-11 Alere San Diego, Inc. Microfluidic immunoassay method
CA2818332C (en) 2012-06-12 2021-07-20 Ortho-Clinical Diagnostics, Inc. Lateral flow assay devices for use in clinical diagnostic apparatus and configuration of clinical diagnostic apparatus for same
EP2695656A1 (de) 2012-08-09 2014-02-12 F. Hoffmann-La Roche AG Verfahren sowie eine Separationsvorrichtung zur Abtrennung eines Filtrats von einer Probenflüssigkeit
EP3203236A1 (en) 2012-11-15 2017-08-09 Ortho-Clinical Diagnostics, Inc. Quality/process control of a lateral flow assay device based on flow monitoring

Also Published As

Publication number Publication date
US11033896B2 (en) 2021-06-15
EP3177928A1 (en) 2017-06-14
US20210268496A1 (en) 2021-09-02
JP6199527B1 (ja) 2017-09-20
US20160038937A1 (en) 2016-02-11
EP3177928B1 (en) 2018-01-03
CN106796232A (zh) 2017-05-31
WO2016022655A1 (en) 2016-02-11
JP2017530339A (ja) 2017-10-12
CA2957728A1 (en) 2016-02-11
CN106796232B (zh) 2018-06-26
CA2957728C (en) 2018-11-20

Similar Documents

Publication Publication Date Title
BR112017002535A2 (pt) dispositivo de análise de fluxo lateral com controle de fluxo de filtração
BR112017002524A2 (pt) dispositivo de análise de fluxo lateral que tem constrições de fluxo
BR112015005318A8 (pt) dispositivo para a captura de uma primeira porção de um fluxo de líquido, kit de peças para a montagem do dispositivo e método de montagem do dispositivo.
MY190947A (en) Fluid control
MX2015015764A (es) Lente oftálmica con sistema microfluídico.
BR112017004191A2 (pt) dispositivo microfluídico, e, método para purificar um analito biológico ou químico.
EA201000555A1 (ru) Устройство регулирования потока
BR112012018663A2 (pt) painel luminoso para veiculo, sua fabricacao
BR112014019091A8 (pt) Elemento filtrante plano, dispositivo de filtração, método de produzir um elemento filtrante plano e uso de um elemento filtrante plano
ES2531400T3 (es) Tarjeta de prueba
BR112017002536A2 (pt) dispositivo de análise de fluxo lateral
BR112015010695A2 (pt) dispositivo de ensaio de ponto de atendimento de baixo custo
BR112015023912A2 (pt) válvula de dispositivo de transferência
BR112015029245A2 (pt) dispositivo de análise de fluido compacto e método de fabricação
BR112017016489A2 (pt) instrumento para realizar um teste de diagnóstico em um cartucho fluídico
DK3202324T3 (da) Medicinsk anordning til påvisning af mindst én analyt i en kropsvæske
WO2013134742A3 (en) Micro-tube particles for microfluidic assays and methods of manufacture
BR112012011254A2 (pt) sistema de válvula boia para um sistema de umidificação respiratória
GB2538731A8 (en) Methods
DK3909506T3 (da) Medicinsk anordning til påvisning af mindst én analyt i en kropsvæske
JP2015537229A5 (pt)
GB2526999A (en) Capillary barriers for staged loading of microfluidic devices
BR112018014452A2 (pt) elemento de filtro, particularmente para filtração de gás
BR112017012933A2 (pt) sistema e método de separação em filtro coalescente
BR112016020499A2 (pt) unidade de controle de fluxo fornecido em um canal de fluxo

Legal Events

Date Code Title Description
B11A Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing
B11Y Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette]