BR112016028127A2 - Status de metilação de dna como um biomarcador de uso e abstinência de álcool - Google Patents

Status de metilação de dna como um biomarcador de uso e abstinência de álcool

Info

Publication number
BR112016028127A2
BR112016028127A2 BR112016028127A BR112016028127A BR112016028127A2 BR 112016028127 A2 BR112016028127 A2 BR 112016028127A2 BR 112016028127 A BR112016028127 A BR 112016028127A BR 112016028127 A BR112016028127 A BR 112016028127A BR 112016028127 A2 BR112016028127 A2 BR 112016028127A2
Authority
BR
Brazil
Prior art keywords
biomarker
withdrawal
dna methylation
methylation status
alcohol use
Prior art date
Application number
BR112016028127A
Other languages
English (en)
Inventor
Philibert Robert
Original Assignee
Philibert Robert
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Philibert Robert filed Critical Philibert Robert
Publication of BR112016028127A2 publication Critical patent/BR112016028127A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2523/00—Reactions characterised by treatment of reaction samples
    • C12Q2523/10—Characterised by chemical treatment
    • C12Q2523/125—Bisulfite(s)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/154—Methylation markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

STATUS DE METILAÇÃO DE DNA COMO UM BIOMARCADOR DE USO E ABSTINÊNCIA DE ÁLCOOL. Esta divulgação fornece métodos e materiais para determinar se um indivíduo está usando álcool ou não e também para determinar se o indivíduo parou ou não de usar álcool.
BR112016028127A 2014-05-30 2015-05-28 Status de metilação de dna como um biomarcador de uso e abstinência de álcool BR112016028127A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201462005408P 2014-05-30 2014-05-30
PCT/IB2015/054041 WO2015181779A2 (en) 2014-05-30 2015-05-28 Dna methylation status as a biomarker of alcohol use and abstinence

Publications (1)

Publication Number Publication Date
BR112016028127A2 true BR112016028127A2 (pt) 2017-08-22

Family

ID=54699995

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112016028127A BR112016028127A2 (pt) 2014-05-30 2015-05-28 Status de metilação de dna como um biomarcador de uso e abstinência de álcool

Country Status (14)

Country Link
US (1) US20170306405A1 (pt)
EP (1) EP3149206B1 (pt)
JP (1) JP6807833B2 (pt)
KR (1) KR20170013921A (pt)
CN (1) CN106661618B (pt)
AU (1) AU2015265431B2 (pt)
BR (1) BR112016028127A2 (pt)
CA (1) CA2947128A1 (pt)
ES (1) ES2827241T3 (pt)
IL (1) IL248602A0 (pt)
MX (1) MX2016015759A (pt)
NO (1) NO20161786A1 (pt)
SG (2) SG10201810760SA (pt)
WO (1) WO2015181779A2 (pt)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201516972D0 (en) * 2015-09-25 2015-11-11 Epiontis Gmbh LRP5 as epigenetic marker for the identification of immune cells, in particular B-cells
US11817214B1 (en) 2019-09-23 2023-11-14 FOXO Labs Inc. Machine learning model trained to determine a biochemical state and/or medical condition using DNA epigenetic data
US11795495B1 (en) 2019-10-02 2023-10-24 FOXO Labs Inc. Machine learned epigenetic status estimator

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010129354A2 (en) * 2009-04-28 2010-11-11 University Of Iowa Research Foundation Compositions and methods for detecting predisposition to a substance use disorder
GB201004147D0 (en) * 2010-03-12 2010-04-28 Dna Electronics Ltd Method and apparatus for sensing methylation
US20120149589A1 (en) * 2010-12-14 2012-06-14 Kent Hutchison Epigentic Markers Associated with Substance Use Disorders

Also Published As

Publication number Publication date
JP2017518077A (ja) 2017-07-06
CN106661618A (zh) 2017-05-10
JP6807833B2 (ja) 2021-01-06
KR20170013921A (ko) 2017-02-07
MX2016015759A (es) 2017-06-06
WO2015181779A3 (en) 2016-03-10
ES2827241T3 (es) 2021-05-20
EP3149206A2 (en) 2017-04-05
EP3149206A4 (en) 2017-11-15
SG10201810760SA (en) 2018-12-28
EP3149206B1 (en) 2020-09-02
CN106661618B (zh) 2021-06-08
WO2015181779A2 (en) 2015-12-03
IL248602A0 (en) 2016-12-29
NO20161786A1 (en) 2016-11-11
CA2947128A1 (en) 2015-12-03
US20170306405A1 (en) 2017-10-26
AU2015265431A1 (en) 2016-11-10
SG11201608817TA (en) 2016-11-29
AU2015265431B2 (en) 2021-04-01

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Legal Events

Date Code Title Description
B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B11B Dismissal acc. art. 36, par 1 of ipl - no reply within 90 days to fullfil the necessary requirements