BR112016021630A2 - Composição para tratar pré-eclampsia, método de uso do nível de anexina a2 (anxa2) como indicador de pré-eclampsia e método para avaliar a eficácia da terapia de glicosaminoglicano para pré-eclampsia - Google Patents
Composição para tratar pré-eclampsia, método de uso do nível de anexina a2 (anxa2) como indicador de pré-eclampsia e método para avaliar a eficácia da terapia de glicosaminoglicano para pré-eclampsia Download PDFInfo
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Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/689—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to pregnancy or the gonads
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
- A61K31/727—Heparin; Heparan
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
- G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/36—Gynecology or obstetrics
- G01N2800/368—Pregnancy complicated by disease or abnormalities of pregnancy, e.g. preeclampsia, preterm labour
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
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- General Physics & Mathematics (AREA)
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- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201461968728P | 2014-03-21 | 2014-03-21 | |
| US61/968,728 | 2014-03-21 | ||
| US201461969520P | 2014-03-24 | 2014-03-24 | |
| US61/969,520 | 2014-03-24 | ||
| PCT/IB2015/001404 WO2015166353A2 (en) | 2014-03-21 | 2015-03-19 | Early detection of preeclampsia |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR112016021630A2 true BR112016021630A2 (pt) | 2020-02-27 |
Family
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Family Applications (1)
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| BR112016021630-0A BR112016021630A2 (pt) | 2014-03-21 | 2015-03-19 | Composição para tratar pré-eclampsia, método de uso do nível de anexina a2 (anxa2) como indicador de pré-eclampsia e método para avaliar a eficácia da terapia de glicosaminoglicano para pré-eclampsia |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20170097358A1 (https=) |
| EP (1) | EP3120152A2 (https=) |
| JP (1) | JP6684263B2 (https=) |
| CN (2) | CN106662589B (https=) |
| BR (1) | BR112016021630A2 (https=) |
| CA (1) | CA2943284A1 (https=) |
| MX (1) | MX384485B (https=) |
| WO (1) | WO2015166353A2 (https=) |
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| WO2010010201A1 (es) | 2008-07-22 | 2010-01-28 | Equipo Ivi Investigacion Sl | Perfil de expresion genetica como marcador de la receptividad endometrial |
| CN107073040A (zh) | 2014-06-17 | 2017-08-18 | 艾基诺米公司 | 子宫内膜病理状况中的干细胞治疗 |
| CA3074808A1 (en) * | 2017-09-05 | 2019-03-14 | Igenomix S.L. | Methods and devices for detecting biomarkers associated with preeclampsia |
| EP3781144A4 (en) * | 2018-03-06 | 2022-01-12 | The Feinstein Institutes for Medical Research | METHODS TO DETECT AND TREAT ENDOMETRIOSIS |
| CN114990038B (zh) * | 2022-05-24 | 2023-06-27 | 郑州大学 | 一种细菌外膜囊泡及其在制备先兆子痫治疗药物中的应用 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5712103A (en) * | 1995-02-13 | 1998-01-27 | Regents Of The University Of California | Diagnostic assay for the prediction of preeclampsia |
| IL127896A0 (en) * | 1998-12-31 | 1999-10-28 | Gail Laster | A novel treatment for preeclampsia and related diseases |
| WO2007030889A1 (en) * | 2005-09-15 | 2007-03-22 | Victor Voroteliak | Method of diagnosing pre-eclampsia |
| WO2008134881A1 (en) * | 2007-05-05 | 2008-11-13 | The University Of Western Ontario | Methods for the detection of preeclampsia |
| EP2019318A1 (en) * | 2007-07-27 | 2009-01-28 | Erasmus University Medical Center Rotterdam | Protein markers for cardiovascular events |
| CN101290321A (zh) * | 2008-04-11 | 2008-10-22 | 中国医学科学院肿瘤研究所 | 膜联蛋白a2的血清检测方法、检测试剂盒及其应用 |
| WO2009143633A1 (en) | 2008-05-30 | 2009-12-03 | Institut De Recherches Cliniques De Montreal | Pcsk9 inhibitors and methods of use thereof |
| CN110208540B (zh) * | 2008-10-31 | 2024-02-09 | 耶鲁大学 | 子痫前期检测和治疗的方法和组合物 |
| US20120107825A1 (en) * | 2010-11-01 | 2012-05-03 | Winger Edward E | Methods and compositions for assessing patients with reproductive failure using immune cell-derived microrna |
| WO2012115885A1 (en) * | 2011-02-22 | 2012-08-30 | Caris Life Sciences Luxembourg Holdings, S.A.R.L. | Circulating biomarkers |
| US9423402B2 (en) * | 2011-11-30 | 2016-08-23 | Singapore Health Services Pte. Ltd. | GM1 ganglioside to annexin V microparticle polypeptide ratio for biological monitoring |
| WO2014001244A1 (en) * | 2012-06-27 | 2014-01-03 | Roche Diagnostics Gmbh | MEANS AND METHODS APPLYING sFlt-1/PlGF OR ENDOGLIN/PlGF RATIO TO RULE-OUT ONSET OF PREECLAMPSIA WITHIN A CERTAIN TIME PERIOD |
| CN103436552A (zh) * | 2013-09-10 | 2013-12-11 | 浙江大学 | 一种人源annexin A2的生产方法及其应用 |
-
2015
- 2015-03-19 BR BR112016021630-0A patent/BR112016021630A2/pt not_active IP Right Cessation
- 2015-03-19 EP EP15766246.1A patent/EP3120152A2/en not_active Withdrawn
- 2015-03-19 WO PCT/IB2015/001404 patent/WO2015166353A2/en not_active Ceased
- 2015-03-19 JP JP2017500456A patent/JP6684263B2/ja not_active Expired - Fee Related
- 2015-03-19 MX MX2016012278A patent/MX384485B/es unknown
- 2015-03-19 CN CN201580021153.7A patent/CN106662589B/zh not_active Expired - Fee Related
- 2015-03-19 CA CA2943284A patent/CA2943284A1/en not_active Abandoned
- 2015-03-19 US US15/127,901 patent/US20170097358A1/en not_active Abandoned
- 2015-03-19 CN CN201910597754.2A patent/CN110927385A/zh active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| JP6684263B2 (ja) | 2020-04-22 |
| WO2015166353A2 (en) | 2015-11-05 |
| WO2015166353A3 (en) | 2016-01-21 |
| CA2943284A1 (en) | 2015-11-05 |
| EP3120152A2 (en) | 2017-01-25 |
| CN106662589B (zh) | 2019-07-30 |
| CN106662589A (zh) | 2017-05-10 |
| JP2017513021A (ja) | 2017-05-25 |
| CN110927385A (zh) | 2020-03-27 |
| US20170097358A1 (en) | 2017-04-06 |
| MX384485B (es) | 2025-03-14 |
| MX2016012278A (es) | 2017-04-27 |
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