BR112016013969A2 - métodos de tratamento ou retardo de progressão de um câncer e de potencialização de função imunológica, uso de um antagonista e de um taxano na produção de um medicamento, composição e ki - Google Patents

métodos de tratamento ou retardo de progressão de um câncer e de potencialização de função imunológica, uso de um antagonista e de um taxano na produção de um medicamento, composição e ki

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Publication number
BR112016013969A2
BR112016013969A2 BR112016013969A BR112016013969A BR112016013969A2 BR 112016013969 A2 BR112016013969 A2 BR 112016013969A2 BR 112016013969 A BR112016013969 A BR 112016013969A BR 112016013969 A BR112016013969 A BR 112016013969A BR 112016013969 A2 BR112016013969 A2 BR 112016013969A2
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Brazil
Prior art keywords
taxane
methods
treating
antagonist
immune function
Prior art date
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BR112016013969A
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English (en)
Other versions
BR112016013969B1 (pt
Inventor
Cheung Jeanne
Kim Jeong
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Genentech Inc
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Application filed by Genentech Inc filed Critical Genentech Inc
Publication of BR112016013969A2 publication Critical patent/BR112016013969A2/pt
Publication of BR112016013969B1 publication Critical patent/BR112016013969B1/pt

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    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/32Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against translation products of oncogenes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/28Compounds containing heavy metals
    • A61K31/282Platinum compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K31/33Heterocyclic compounds
    • A61K31/555Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
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Abstract

a invenção prevê métodos e composições para o tratamento de câncer e para potencializar a função imunológica em um indivíduo com câncer.os métodos compreendem a administração de um antagonista de ligação do eixo pd-1 e um taxano.
BR112016013969-0A 2013-12-17 2014-12-17 Usos de um anticorpo anti-pd-l1, composições e kits BR112016013969B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361917264P 2013-12-17 2013-12-17
US61/917,264 2013-12-17
PCT/US2014/070974 WO2015095404A2 (en) 2013-12-17 2014-12-17 Methods of treating cancers using pd-1 axis binding antagonists and taxanes

Publications (2)

Publication Number Publication Date
BR112016013969A2 true BR112016013969A2 (pt) 2017-10-10
BR112016013969B1 BR112016013969B1 (pt) 2023-05-23

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KR20160089524A (ko) 2016-07-27
KR20240017102A (ko) 2024-02-06
SI3083686T2 (sl) 2023-06-30
US20160257752A1 (en) 2016-09-08
RS59659B1 (sr) 2020-01-31
US20200392249A1 (en) 2020-12-17
AU2020233642A1 (en) 2020-10-08
US20170008971A1 (en) 2017-01-12
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MX2021013520A (es) 2021-12-10
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AU2014364587A1 (en) 2016-06-16
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SG11201604956SA (en) 2016-07-28
EP3680254A1 (en) 2020-07-15
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HK1225634A1 (zh) 2017-09-15
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US20220002437A1 (en) 2022-01-06
ES2763429T3 (es) 2020-05-28
EP3083686B1 (en) 2019-10-23
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FI3083686T4 (fi) 2023-05-09
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