BR112016009194B1 - Métodos in vitro para selecionar uma variação em um gene do receptor de prolactina (prlr), produzir uma célula ou embrião de animal não humano, gerar um animal não humano e selecionar uma variação em um gene do prlr - Google Patents

Métodos in vitro para selecionar uma variação em um gene do receptor de prolactina (prlr), produzir uma célula ou embrião de animal não humano, gerar um animal não humano e selecionar uma variação em um gene do prlr Download PDF

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BR112016009194B1
BR112016009194B1 BR112016009194-9A BR112016009194A BR112016009194B1 BR 112016009194 B1 BR112016009194 B1 BR 112016009194B1 BR 112016009194 A BR112016009194 A BR 112016009194A BR 112016009194 B1 BR112016009194 B1 BR 112016009194B1
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animal
prlr
genetic
gene
embryo
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BR112016009194-9A
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Mathew Douglas Littlejohn
Stephen Richard Davis
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Livestock Improvement Corporation Limited
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    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
    • A01K67/027—New or modified breeds of vertebrates
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/72—Receptors; Cell surface antigens; Cell surface determinants for hormones
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
    • A01K67/027—New or modified breeds of vertebrates
    • A01K67/0273—Cloned vertebrates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2227/00—Animals characterised by species
    • A01K2227/10—Mammal
    • A01K2227/101—Bovine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/124—Animal traits, i.e. production traits, including athletic performance or the like
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Health & Medical Sciences (AREA)
  • Environmental Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Animal Husbandry (AREA)
  • Biodiversity & Conservation Biology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Cell Biology (AREA)
  • Endocrinology (AREA)
  • Veterinary Medicine (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
BR112016009194-9A 2013-10-25 2014-10-24 Métodos in vitro para selecionar uma variação em um gene do receptor de prolactina (prlr), produzir uma célula ou embrião de animal não humano, gerar um animal não humano e selecionar uma variação em um gene do prlr BR112016009194B1 (pt)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
NZ61704013 2013-10-25
NZ617040 2013-10-25
NZ62515014 2014-05-20
NZ625150 2014-05-20
NZ627209 2014-07-08
NZ62720914 2014-07-08
NZ630540 2014-09-12
NZ63054014 2014-09-12
PCT/NZ2014/000224 WO2015060732A1 (en) 2013-10-25 2014-10-24 Genetic markers and uses therefor

Publications (2)

Publication Number Publication Date
BR112016009194A2 BR112016009194A2 (https=) 2017-09-19
BR112016009194B1 true BR112016009194B1 (pt) 2022-05-24

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BR112016009194-9A BR112016009194B1 (pt) 2013-10-25 2014-10-24 Métodos in vitro para selecionar uma variação em um gene do receptor de prolactina (prlr), produzir uma célula ou embrião de animal não humano, gerar um animal não humano e selecionar uma variação em um gene do prlr

Country Status (9)

Country Link
US (2) US10779518B2 (https=)
EP (2) EP3060682B1 (https=)
CN (2) CN105814214A (https=)
AP (1) AP2016009207A0 (https=)
AU (1) AU2014337790B2 (https=)
BR (1) BR112016009194B1 (https=)
ES (1) ES2962492T3 (https=)
MX (1) MX388563B (https=)
WO (1) WO2015060732A1 (https=)

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WO2017040695A1 (en) * 2015-09-01 2017-03-09 Recombinetics, Inc. Method of identifying the presence of foreign alleles in a desired haplotype
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CN111455072B (zh) * 2020-05-29 2021-09-14 华中农业大学 可用于鉴别瘤牛和普通牛血统的基因组序列及其应用方法
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IL316038A (en) 2022-04-04 2024-11-01 Univ California Preparations and methods for genetic complementation
CN121160698B (zh) * 2025-09-26 2026-04-10 山东省农业科学院畜牧兽医研究所 一种修饰的gRNA及通过基因编辑生产耐热奶牛的方法

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CN121065345A (zh) 2025-12-05
US20200375156A1 (en) 2020-12-03
EP3060682B1 (en) 2023-08-30
US20160262360A1 (en) 2016-09-15
ES2962492T3 (es) 2024-03-19
EP4273268A3 (en) 2024-02-21
EP3060682A4 (en) 2017-07-05
MX388563B (es) 2025-03-20
AU2014337790A1 (en) 2016-05-19
US10779518B2 (en) 2020-09-22
AU2014337790B2 (en) 2019-09-26
EP3060682C0 (en) 2023-08-30
AP2016009207A0 (en) 2016-05-31
BR112016009194A2 (https=) 2017-09-19
MX2016005379A (es) 2017-02-15
WO2015060732A1 (en) 2015-04-30
CN105814214A (zh) 2016-07-27
EP3060682A1 (en) 2016-08-31
EP4273268A2 (en) 2023-11-08
EP4273268A9 (en) 2024-10-30

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