BR112016008029A2 - METHOD OF PRODUCING L-AMINO ACIDS - Google Patents

METHOD OF PRODUCING L-AMINO ACIDS

Info

Publication number
BR112016008029A2
BR112016008029A2 BR112016008029A BR112016008029A BR112016008029A2 BR 112016008029 A2 BR112016008029 A2 BR 112016008029A2 BR 112016008029 A BR112016008029 A BR 112016008029A BR 112016008029 A BR112016008029 A BR 112016008029A BR 112016008029 A2 BR112016008029 A2 BR 112016008029A2
Authority
BR
Brazil
Prior art keywords
producing
amino acids
choryneform
microorganism
recombinant
Prior art date
Application number
BR112016008029A
Other languages
Portuguese (pt)
Inventor
Ok Moon Jun
Jo Lim Sang
Hyun Kwon Do
Ho Lee Kwang
Won Bae Hyun
Original Assignee
Cj Cheiljedang Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cj Cheiljedang Corp filed Critical Cj Cheiljedang Corp
Priority claimed from PCT/KR2014/009468 external-priority patent/WO2015053552A1/en
Publication of BR112016008029A2 publication Critical patent/BR112016008029A2/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C12N15/77—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Corynebacterium; for Brevibacterium
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88—Lyases (4.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/08—Lysine; Diaminopimelic acid; Threonine; Valine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y403/00—Carbon-nitrogen lyases (4.3)
    • C12Y403/03—Amine-lyases (4.3.3)
    • C12Y403/03007—4-Hydroxy-tetrahydrodipicolinate synthase (4.3.3.7)

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)

Abstract

MÉTODO DE PRODUZIR L-AMINOÁCIDOS. Fornecido é um método de produzir L-aminoácidos usando-se um microorganismo corineforme recombinante em que a expressão de um gene alvo é enfraquecida usando-se um método de inibição de transcrição gênica.METHOD OF PRODUCING L-AMINO ACIDS. Provided is a method of producing L-amino acids using a recombinant choryneform microorganism in which expression of a target gene is impaired using a gene transcription inhibition method.

BR112016008029A 2013-10-11 2014-10-08 METHOD OF PRODUCING L-AMINO ACIDS BR112016008029A2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
KR20130121090 2013-10-11
KR1020140091307A KR101518860B1 (en) 2013-10-11 2014-07-18 Method for producing L-amino acid
PCT/KR2014/009468 WO2015053552A1 (en) 2013-10-11 2014-10-08 Method of producing l-amino acids

Publications (1)

Publication Number Publication Date
BR112016008029A2 true BR112016008029A2 (en) 2017-10-03

Family

ID=53035683

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112016008029A BR112016008029A2 (en) 2013-10-11 2014-10-08 METHOD OF PRODUCING L-AMINO ACIDS

Country Status (16)

Country Link
JP (3) JP6291042B2 (en)
KR (1) KR101518860B1 (en)
CN (1) CN104561163B (en)
AR (1) AR097977A1 (en)
AU (2) AU2014332732B2 (en)
BR (1) BR112016008029A2 (en)
CA (1) CA2925659C (en)
DK (1) DK2860256T3 (en)
ES (1) ES2626048T3 (en)
GE (1) GEP20196943B (en)
JO (1) JO3255B1 (en)
MY (1) MY172463A (en)
PH (1) PH12016500640B1 (en)
PL (1) PL2860256T3 (en)
RU (2) RU2651461C2 (en)
UA (1) UA117935C2 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101518860B1 (en) * 2013-10-11 2015-05-12 씨제이제일제당 (주) Method for producing L-amino acid
CN105734004B (en) * 2016-03-02 2020-06-19 廊坊梅花生物技术开发有限公司 Recombinant strain and preparation method and application thereof
KR101925930B1 (en) * 2017-07-24 2019-02-26 씨제이제일제당 주식회사 Microorganisms producing L-lysine and process for producing L-lysine using the same
WO2019172702A1 (en) 2018-03-09 2019-09-12 씨제이제일제당 (주) Novel promoter and l-amino acid production method using same
KR102221040B1 (en) * 2019-05-09 2021-03-03 씨제이제일제당 주식회사 Microorganism producing L-amino acid and method of producing Method of L-amino acid using thereof
KR102134418B1 (en) * 2019-06-17 2020-07-16 씨제이제일제당 주식회사 A microorganism producing L-tyrosine and a method for producing L-tyrosine using thereof
KR102207867B1 (en) * 2020-01-21 2021-01-26 씨제이제일제당 주식회사 Method for producing L-amino acids using microorganisms containing NADP dependent glyceraldehyde-3-phosphate dehydrogenase

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6649379B1 (en) * 1987-06-12 2003-11-18 Massachusetts Institute Of Technology Method and deregulated enzyme for threonine production
JP3036912B2 (en) * 1991-09-02 2000-04-24 協和醗酵工業株式会社 Gene expression regulatory DNA
DE69534592T2 (en) * 1994-03-04 2006-08-10 Ajinomoto Co., Inc. PROCESS FOR THE PREPARATION OF L-LYSINE
ZA964665B (en) * 1995-06-07 1997-01-07 Ajinomoto Kk Method of producing l-lysine
ATE263246T1 (en) * 1999-02-20 2004-04-15 Degussa METHOD FOR THE FERMENTATIVE PRODUCTION OF L-AMINO ACIDS USING CORYNEFORMER BACTERIA
WO2001048146A1 (en) * 1999-12-24 2001-07-05 Ajinomoto Co., Inc. Process for producing l-amino acid and novel gene
US7141388B2 (en) * 2000-11-15 2006-11-28 Archer-Daniels-Midland Company Nucleotide sequences for transcriptional regulation in corynebacterium glutamicum
KR100397423B1 (en) * 2001-02-13 2003-09-13 씨제이 주식회사 Process for producing L-threonine
DE10224088A1 (en) * 2002-05-31 2003-12-11 Degussa Process for the production of L-amino acids using coryneform bacteria which contain an attenuated mez gene
JP2004261150A (en) * 2003-03-04 2004-09-24 Ajinomoto Co Inc Method for producing objective material
JP2005006564A (en) 2003-06-19 2005-01-13 Japan Tobacco Inc Nitrate ion-inducing promoter
JP2010226956A (en) * 2007-07-23 2010-10-14 Ajinomoto Co Inc Method for producing l-lysine
KR101335853B1 (en) 2011-12-01 2013-12-02 씨제이제일제당 (주) A microorganism having L-amino acids and riboflavin productivity and a method of producing L-amino acids and riboflavin using the same
KR101518860B1 (en) * 2013-10-11 2015-05-12 씨제이제일제당 (주) Method for producing L-amino acid

Also Published As

Publication number Publication date
UA117935C2 (en) 2018-10-25
MY172463A (en) 2019-11-26
AU2014332732A1 (en) 2016-04-21
RU2651461C2 (en) 2018-04-19
CA2925659A1 (en) 2015-04-16
AU2017272295B2 (en) 2019-05-16
ES2626048T3 (en) 2017-07-21
GEP20196943B (en) 2019-02-11
JP2018113966A (en) 2018-07-26
AU2014332732B2 (en) 2017-12-07
PH12016500640A1 (en) 2016-05-30
JP6824918B2 (en) 2021-02-03
RU2614258C2 (en) 2017-03-24
KR20150042692A (en) 2015-04-21
JP6291042B2 (en) 2018-03-14
CN104561163B (en) 2018-11-06
JO3255B1 (en) 2018-09-16
AR097977A1 (en) 2016-04-20
CA2925659C (en) 2018-10-23
JP2020078312A (en) 2020-05-28
JP2016532439A (en) 2016-10-20
CN104561163A (en) 2015-04-29
PH12016500640B1 (en) 2016-05-30
RU2016110804A (en) 2016-07-27
DK2860256T3 (en) 2017-06-06
RU2015151124A (en) 2016-06-27
PL2860256T3 (en) 2017-08-31
KR101518860B1 (en) 2015-05-12
AU2017272295A1 (en) 2018-01-04

Similar Documents

Publication Publication Date Title
BR112016008029A2 (en) METHOD OF PRODUCING L-AMINO ACIDS
BRPI1100666A2 (en) METHOD FOR PRODUCING L-AMINO ACID
BR112017016301A2 (en) new promoter and uses of it
BR112013024246A2 (en) energy layer functional insert
DK3041854T3 (en) A PROCEDURE FOR LOCAL SPECIFIC ENZYMATIC LABELING OF NUCLEIC ACIDS IN VITRO THROUGH INCORPORATION OF UNNATURAL NUCLEOTIDES
AU2015205241A1 (en) Method for operating blast furnace
BR112016022667A2 (en) USE OF D-PANTOTHENYL ALCOHOL FOR THE MANUFACTURE OF MELANOGENESIS INHIBITORS AND SKIN WHITENING METHOD
BR112013027726A2 (en) underwater well installation and associated method
CO2017000367A2 (en) Microbial production of fatty diols
BR112018001231A2 (en) microorganisms to produce putrescine or ornithine and process to produce putrescine or ornithine using the same
MY183321A (en) Microorganism producing o-acetyl-homoserine and method for producing o-acetylhomoserine using the same
BR112013032337A2 (en) method for controlling a pump
BR112013025870A2 (en) lighting duct puller
BR102014009838B8 (en) METHOD FOR PRODUCING AN L-AMINO ACID
MY171648A (en) Microorganism producing l-lysine and method for producing l-lysine using the same
BR112016013461A2 (en) corineform microorganism with an improved ability to produce l-lysine, and method for producing l-lysine
PL3342869T3 (en) Microorganism of genus corynebacterium for producing l-amino acid and method for producing l-amino acid by using same
BR112016027341A2 (en) A method of producing L-amino acid by using this energy level is enhanced and microorganism cells
BR112017024401A2 (en) ? microorganism of the genus escherichia that produces l-tryptophan and method for producing l-tryptophan using it?
BR112017005645A2 (en) method of preparing cinnamaldehyde
UA114997C2 (en) Microorganisms producing l-amino acids and process for producing l-amino acids using the same
BR112016027819A8 (en) process for preparing thiazole derivatives
BR112015004488A2 (en) method of co-producing a terpene and at least one co-product from a fermentable carbon source
MX2016010130A (en) A modified microorganism having enhanced biomass synthesis capacity and a method thereof.
DE112015005318A5 (en) Process for acidification in hydrolysis plants for the acidic hydrolysis of vegetable biomass by means of concentrated hydrochloric acid

Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B350 Update of information on the portal [chapter 15.35 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]
B12B Appeal against refusal [chapter 12.2 patent gazette]