BR112016006059A2 - ?método para produzir álcoois fragrantes? - Google Patents

?método para produzir álcoois fragrantes?

Info

Publication number
BR112016006059A2
BR112016006059A2 BR112016006059A BR112016006059A BR112016006059A2 BR 112016006059 A2 BR112016006059 A2 BR 112016006059A2 BR 112016006059 A BR112016006059 A BR 112016006059A BR 112016006059 A BR112016006059 A BR 112016006059A BR 112016006059 A2 BR112016006059 A2 BR 112016006059A2
Authority
BR
Brazil
Prior art keywords
fragrant alcohols
producing fragrant
producing
alcohols
sesquiterpene
Prior art date
Application number
BR112016006059A
Other languages
English (en)
Other versions
BR112016006059B1 (pt
Inventor
Daviet Laurent
Rocci Leticia
Schalk Michel
Original Assignee
Firmenich & Cie
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Firmenich & Cie filed Critical Firmenich & Cie
Publication of BR112016006059A2 publication Critical patent/BR112016006059A2/pt
Publication of BR112016006059B1 publication Critical patent/BR112016006059B1/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P5/00—Preparation of hydrocarbons or halogenated hydrocarbons
    • C12P5/007—Preparation of hydrocarbons or halogenated hydrocarbons containing one or more isoprene units, i.e. terpenes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0071—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0071—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
    • C12N9/0077—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14) with a reduced iron-sulfur protein as one donor (1.14.15)
    • C12N9/0079—Steroid 11 beta monooxygenase (P-450 protein)(1.14.15.4)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y114/00—Oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (1.14)
    • C12Y114/13—Oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (1.14) with NADH or NADPH as one donor, and incorporation of one atom of oxygen (1.14.13)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y114/00—Oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (1.14)
    • C12Y114/14—Oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (1.14) with reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen (1.14.14)
    • C12Y114/14001—Unspecific monooxygenase (1.14.14.1)

Abstract

métodos e composições para produzir um álcool sesquiterpeno que compreendem colocar um sesquiterpeno em contato com um polipeptídeo de p450 com atividade de monooxigenase.
BR112016006059-8A 2013-09-19 2014-09-19 Método para produzir álcoois fragrantes BR112016006059B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361880149P 2013-09-19 2013-09-19
US61/880,149 2013-09-19
PCT/EP2014/070060 WO2015040197A1 (en) 2013-09-19 2014-09-19 Method for producing fragrant alcohols

Publications (2)

Publication Number Publication Date
BR112016006059A2 true BR112016006059A2 (pt) 2017-09-26
BR112016006059B1 BR112016006059B1 (pt) 2022-09-20

Family

ID=51582407

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112016006059-8A BR112016006059B1 (pt) 2013-09-19 2014-09-19 Método para produzir álcoois fragrantes

Country Status (9)

Country Link
US (4) US9909145B2 (pt)
EP (1) EP3047027A1 (pt)
JP (1) JP6410802B2 (pt)
CN (2) CN112176000A (pt)
BR (1) BR112016006059B1 (pt)
CA (1) CA2924541A1 (pt)
MX (1) MX2016003431A (pt)
RU (1) RU2654670C2 (pt)
WO (1) WO2015040197A1 (pt)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6410802B2 (ja) 2013-09-19 2018-10-24 フイルメニツヒ ソシエテ アノニムＦｉｒｍｅｎｉｃｈ Ｓａ 芳香性アルコールの製造方法
US11293040B2 (en) * 2016-07-20 2022-04-05 Firmenich Sa Methods of producing sesquiterpene compounds
NL2018457B1 (en) 2017-03-02 2018-09-21 Isobionics B V Santalene Synthase
WO2019141739A1 (en) * 2018-01-18 2019-07-25 Firmenich Sa Cytochrome p450 monooxygenase catalyzed oxidation of sesquiterpenes
SG11202007273WA (en) * 2018-01-31 2020-08-28 Univ Michigan Regents Biocatalyst and methods for synthesizing mixed disulfide conjugates of thienopyridine compounds
CN116875518A (zh) 2018-07-06 2023-10-13 科罗拉多州立大学董事会法人团体 用于构建和检测生物活性剂的基因编码系统
CN111434773B (zh) * 2019-01-15 2021-06-18 天津大学 一种高产檀香油的重组酵母菌及其构建方法与应用
NL2023931B1 (en) * 2019-10-02 2021-06-01 Isobionics B V Oxidation of santalene to santalol
MX2022007440A (es) * 2019-12-23 2022-06-24 Firmenich & Cie Aceite de sandalo producido bioquimicamente.
CA3165502A1 (en) * 2020-01-23 2021-07-29 Christopher J. Paddon Amorpha-4,11-diene 12-monooxygenase variants and uses thereof
CN114181964B (zh) * 2021-11-02 2023-06-09 云南大学 一种表达盒组合、重组载体和重组酿酒酵母及其应用

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2285044C2 (ru) * 1999-07-27 2006-10-10 Басф Акциенгезельшафт Новые цитохром р450-монооксигеназы и их применение для окисления органических соединений
AR034703A1 (es) * 2001-05-16 2004-03-17 Syngenta Participations Ag Metodos y composiciones para preparar emamectina.
WO2003025193A1 (en) * 2001-09-17 2003-03-27 Plant Research International B.V. Plant enzymes for bioconversion
WO2005056803A1 (en) * 2003-12-09 2005-06-23 Firmenich Sa Sesquiterpene synthases from patchouli
CN101495499B (zh) * 2005-07-05 2013-09-04 加利福尼亚大学董事会 编码类异戊烯修饰酶的多核苷酸和其使用方法
CA2623687A1 (en) * 2005-10-07 2007-04-19 The Regents Of The University Of California Nucleic acids encoding modified cytochrome p450 enzymes and methods of use thereof
FR2914652B1 (fr) * 2007-04-03 2013-01-18 Librophyt Genes codant pour z,z-farnesyl diphosphate synthase et une sesquiterpene synthase a produits multiples et leurs utilisations
WO2009109597A1 (en) 2008-03-06 2009-09-11 Firmenich Sa Method for producing alpha- santalene
EP3241906A1 (en) 2008-12-11 2017-11-08 Firmenich SA Method for producing beta-santalene
WO2012109586A2 (en) * 2011-02-11 2012-08-16 University Of Rochester Methods and systems for evaluating and predicting the reactivity of monooxygenase enzymes
RU2625224C2 (ru) 2011-11-01 2017-07-12 Фирмениш Са Цитохром p450 и его применение для энзиматического окисления терпенов
US9885023B2 (en) * 2012-11-01 2018-02-06 University Of British Columbia Cytochrome P450 and cytochrome P450 reductase polypeptides, encoding nucleic acid molecules and uses thereof
CN103006736A (zh) * 2012-11-30 2013-04-03 深圳海王药业有限公司 苍术总萜醇提取物在制备抗幽门螺杆菌药物中的应用
JP6410802B2 (ja) * 2013-09-19 2018-10-24 フイルメニツヒ ソシエテ アノニムＦｉｒｍｅｎｉｃｈ Ｓａ 芳香性アルコールの製造方法

Also Published As

Publication number Publication date
WO2015040197A1 (en) 2015-03-26
US20180208946A1 (en) 2018-07-26
RU2654670C2 (ru) 2018-05-21
JP6410802B2 (ja) 2018-10-24
CA2924541A1 (en) 2015-03-26
JP2016533707A (ja) 2016-11-04
MX2016003431A (es) 2016-06-30
CN105555959A (zh) 2016-05-04
US20160215301A1 (en) 2016-07-28
EP3047027A1 (en) 2016-07-27
CN112176000A (zh) 2021-01-05
CN105555959B (zh) 2020-10-27
US11130972B2 (en) 2021-09-28
US20200172936A1 (en) 2020-06-04
US20220056485A1 (en) 2022-02-24
RU2016114987A (ru) 2017-10-24
BR112016006059B1 (pt) 2022-09-20
US10570420B2 (en) 2020-02-25
US9909145B2 (en) 2018-03-06

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B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B350 Update of information on the portal [chapter 15.35 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

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