BR112016004124B1 - Método para selecionar uma agulha com uma extensão de injeção para injeção subcutânea de um agente terapêutico - Google Patents
Método para selecionar uma agulha com uma extensão de injeção para injeção subcutânea de um agente terapêutico Download PDFInfo
- Publication number
- BR112016004124B1 BR112016004124B1 BR112016004124-0A BR112016004124A BR112016004124B1 BR 112016004124 B1 BR112016004124 B1 BR 112016004124B1 BR 112016004124 A BR112016004124 A BR 112016004124A BR 112016004124 B1 BR112016004124 B1 BR 112016004124B1
- Authority
- BR
- Brazil
- Prior art keywords
- needle
- injection
- body fat
- site
- length
- Prior art date
Links
- 238000002347 injection Methods 0.000 title claims abstract description 75
- 239000007924 injection Substances 0.000 title claims abstract description 75
- 238000000034 method Methods 0.000 title claims abstract description 40
- 239000003814 drug Substances 0.000 title claims abstract description 28
- 229940124597 therapeutic agent Drugs 0.000 title claims abstract description 24
- 238000010254 subcutaneous injection Methods 0.000 title claims abstract description 15
- 239000007929 subcutaneous injection Substances 0.000 title claims abstract description 15
- 210000000577 adipose tissue Anatomy 0.000 claims description 77
- 238000005259 measurement Methods 0.000 claims description 41
- NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 claims description 10
- 210000001015 abdomen Anatomy 0.000 claims description 9
- 108060003951 Immunoglobulin Proteins 0.000 claims description 6
- 102000018358 immunoglobulin Human genes 0.000 claims description 6
- 102000004877 Insulin Human genes 0.000 claims description 5
- 108090001061 Insulin Proteins 0.000 claims description 5
- 230000006835 compression Effects 0.000 claims description 5
- 238000007906 compression Methods 0.000 claims description 5
- 229940125396 insulin Drugs 0.000 claims description 5
- 210000000689 upper leg Anatomy 0.000 claims description 5
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 claims description 4
- 229940072221 immunoglobulins Drugs 0.000 claims description 3
- HTTJABKRGRZYRN-UHFFFAOYSA-N Heparin Chemical compound OC1C(NC(=O)C)C(O)OC(COS(O)(=O)=O)C1OC1C(OS(O)(=O)=O)C(O)C(OC2C(C(OS(O)(=O)=O)C(OC3C(C(O)C(O)C(O3)C(O)=O)OS(O)(=O)=O)C(CO)O2)NS(O)(=O)=O)C(C(O)=O)O1 HTTJABKRGRZYRN-UHFFFAOYSA-N 0.000 claims description 2
- 238000011393 cytotoxic chemotherapy Methods 0.000 claims description 2
- 238000002637 fluid replacement therapy Methods 0.000 claims description 2
- 239000003102 growth factor Substances 0.000 claims description 2
- 229960002897 heparin Drugs 0.000 claims description 2
- 229920000669 heparin Polymers 0.000 claims description 2
- 229940088597 hormone Drugs 0.000 claims description 2
- 239000005556 hormone Substances 0.000 claims description 2
- 238000002649 immunization Methods 0.000 claims description 2
- 230000003053 immunization Effects 0.000 claims description 2
- 229910052742 iron Inorganic materials 0.000 claims description 2
- 229940005483 opioid analgesics Drugs 0.000 claims description 2
- 238000011282 treatment Methods 0.000 claims description 2
- 206010039897 Sedation Diseases 0.000 claims 1
- 229960003284 iron Drugs 0.000 claims 1
- 239000004081 narcotic agent Substances 0.000 claims 1
- 230000036280 sedation Effects 0.000 claims 1
- 210000003491 skin Anatomy 0.000 description 55
- 210000004207 dermis Anatomy 0.000 description 15
- 230000002500 effect on skin Effects 0.000 description 14
- 210000001519 tissue Anatomy 0.000 description 12
- 238000007920 subcutaneous administration Methods 0.000 description 11
- 210000003205 muscle Anatomy 0.000 description 8
- 238000001802 infusion Methods 0.000 description 6
- 229940079593 drug Drugs 0.000 description 4
- 206010033675 panniculitis Diseases 0.000 description 3
- 210000004304 subcutaneous tissue Anatomy 0.000 description 3
- 238000002560 therapeutic procedure Methods 0.000 description 3
- 230000002596 correlated effect Effects 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 210000005224 forefinger Anatomy 0.000 description 2
- 230000003211 malignant effect Effects 0.000 description 2
- 230000008961 swelling Effects 0.000 description 2
- 210000003813 thumb Anatomy 0.000 description 2
- 208000013016 Hypoglycemia Diseases 0.000 description 1
- 208000003251 Pruritus Diseases 0.000 description 1
- 238000005452 bending Methods 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 210000000078 claw Anatomy 0.000 description 1
- 238000004140 cleaning Methods 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 238000012377 drug delivery Methods 0.000 description 1
- 210000002615 epidermis Anatomy 0.000 description 1
- 210000003811 finger Anatomy 0.000 description 1
- 210000003630 histaminocyte Anatomy 0.000 description 1
- 239000002085 irritant Substances 0.000 description 1
- 231100000021 irritant Toxicity 0.000 description 1
- 230000007803 itching Effects 0.000 description 1
- 238000012153 long-term therapy Methods 0.000 description 1
- 238000000691 measurement method Methods 0.000 description 1
- 238000002483 medication Methods 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 230000003533 narcotic effect Effects 0.000 description 1
- 238000002638 palliative care Methods 0.000 description 1
- 230000035515 penetration Effects 0.000 description 1
- 231100000241 scar Toxicity 0.000 description 1
- 239000000932 sedative agent Substances 0.000 description 1
- 230000001624 sedative effect Effects 0.000 description 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/103—Measuring devices for testing the shape, pattern, colour, size or movement of the body or parts thereof, for diagnostic purposes
- A61B5/107—Measuring physical dimensions, e.g. size of the entire body or parts thereof
- A61B5/1075—Measuring physical dimensions, e.g. size of the entire body or parts thereof for measuring dimensions by non-invasive methods, e.g. for determining thickness of tissue layer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/0048—Detecting, measuring or recording by applying mechanical forces or stimuli
- A61B5/0053—Detecting, measuring or recording by applying mechanical forces or stimuli by applying pressure, e.g. compression, indentation, palpation, grasping, gauging
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/44—Detecting, measuring or recording for evaluating the integumentary system, e.g. skin, hair or nails
- A61B5/441—Skin evaluation, e.g. for skin disorder diagnosis
- A61B5/442—Evaluating skin mechanical properties, e.g. elasticity, hardness, texture, wrinkle assessment
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/44—Detecting, measuring or recording for evaluating the integumentary system, e.g. skin, hair or nails
- A61B5/441—Skin evaluation, e.g. for skin disorder diagnosis
- A61B5/443—Evaluating skin constituents, e.g. elastin, melanin, water
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/48—Other medical applications
- A61B5/4869—Determining body composition
- A61B5/4872—Body fat
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
- A61B5/6846—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive
- A61B5/6847—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive mounted on an invasive device
- A61B5/6848—Needles
- A61B5/6849—Needles in combination with a needle set
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/158—Needles for infusions; Accessories therefor, e.g. for inserting infusion needles, or for holding them on the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/46—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests having means for controlling depth of insertion
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Physics & Mathematics (AREA)
- Pathology (AREA)
- Surgery (AREA)
- Molecular Biology (AREA)
- Medical Informatics (AREA)
- Biophysics (AREA)
- Anesthesiology (AREA)
- Vascular Medicine (AREA)
- Hematology (AREA)
- Dermatology (AREA)
- Dentistry (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361870739P | 2013-08-27 | 2013-08-27 | |
| US61/870,739 | 2013-08-27 | ||
| PCT/US2014/052937 WO2015031490A1 (en) | 2013-08-27 | 2014-08-27 | Method of selecting a needle for subcutaneous therapy |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| BR112016004124A8 BR112016004124A8 (pt) | 2020-02-11 |
| BR112016004124B1 true BR112016004124B1 (pt) | 2022-07-05 |
Family
ID=52587293
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112016004124-0A BR112016004124B1 (pt) | 2013-08-27 | 2014-08-27 | Método para selecionar uma agulha com uma extensão de injeção para injeção subcutânea de um agente terapêutico |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US10278618B2 (enExample) |
| EP (1) | EP3038680B1 (enExample) |
| JP (1) | JP6785157B2 (enExample) |
| KR (1) | KR102320331B1 (enExample) |
| CN (1) | CN105682719B (enExample) |
| BR (1) | BR112016004124B1 (enExample) |
| CA (1) | CA2921971C (enExample) |
| WO (1) | WO2015031490A1 (enExample) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11278669B2 (en) | 2020-01-21 | 2022-03-22 | Repro Med Systems, Inc. | Gear-driven infusion assemblies, systems, and methods |
Family Cites Families (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US268254A (en) * | 1882-11-28 | Electric-arc lamp | ||
| US4233743A (en) * | 1977-02-03 | 1980-11-18 | Health & Education Services Corporation | Skin-fold caliper |
| US4235234A (en) * | 1978-11-30 | 1980-11-25 | Martin John K Iii | Subcutaneous injection system |
| US4321752A (en) * | 1980-01-16 | 1982-03-30 | Kaufman Richard C | Method and apparatus for measuring body fat |
| USD268245S (en) | 1980-05-08 | 1983-03-15 | Matsushita Electric Industrial Co., Ltd. | Wine cork remover |
| US4675006A (en) * | 1986-01-06 | 1987-06-23 | Regents Of The University Of Minnesota | Needle support system |
| JPH0247925Y2 (enExample) * | 1986-07-09 | 1990-12-17 | ||
| US5156161A (en) * | 1991-08-02 | 1992-10-20 | Lollar John A | Skinfold caliper for body fat measurement |
| GB9203945D0 (en) * | 1992-02-25 | 1992-04-08 | Pringle Robert Eng Ltd | Measuring calliper |
| JPH1099300A (ja) * | 1996-09-26 | 1998-04-21 | Terumo Corp | 体脂肪計 |
| US20070259806A1 (en) * | 1996-10-11 | 2007-11-08 | Human Genome Sciences, Inc. | Brain-Associated Inhibitor of Tissue-Type Plasminogen Activator |
| GB2349473B (en) * | 1999-03-04 | 2003-05-28 | Bert Corp Ltd | Electronic caliper and apparatus for calculating body fat percentage and/or body density |
| US6494865B1 (en) * | 1999-10-14 | 2002-12-17 | Becton Dickinson And Company | Intradermal delivery device including a needle assembly |
| JP2004534564A (ja) * | 2001-01-31 | 2004-11-18 | ノボ ノルディスク アクティーゼルスカブ | 利用可能な針のサイズを決定する装置並びに方法 |
| WO2002087494A2 (en) * | 2001-04-27 | 2002-11-07 | Glaxosmithkline Biologicals, Sa | Novel vaccine |
| JP4908977B2 (ja) | 2006-09-05 | 2012-04-04 | 興和株式会社 | 眼内レンズの挿入器具 |
| KR100884689B1 (ko) * | 2007-07-27 | 2009-02-18 | 최종수 | 주사기용 니들 조립체 |
| US20100130958A1 (en) * | 2008-11-26 | 2010-05-27 | David Kang | Device and Methods for Subcutaneous Delivery of High Viscosity Fluids |
| EP2467059B1 (en) * | 2009-08-21 | 2019-11-06 | Beth Israel Deaconess Medical Center, Inc. | A hand-held device for electrical impedance myography |
| US9265461B2 (en) * | 2009-09-01 | 2016-02-23 | Massachusetts Institute Of Technology | Identification techniques and device for testing the efficacy of beauty care products and cosmetics |
| CA2810078A1 (en) * | 2010-09-15 | 2012-03-22 | Zogenix, Inc. | Needle-free injectors and design parameters thereof that optimize injection performance |
| US20120101475A1 (en) * | 2010-10-21 | 2012-04-26 | Meridian Medical Technologies, Inc. | High Efficiency Auto-Injector |
| US20120157854A1 (en) * | 2010-12-15 | 2012-06-21 | Cook Incorporated | System and method for gaining percutaneous access to a body lumen |
| EP2760509B1 (en) * | 2011-09-27 | 2023-04-05 | Becton Dickinson France | Use of plasma treated silicone oil as a coating in a medical injection device |
| US8628724B2 (en) * | 2012-01-03 | 2014-01-14 | Charleston Area Medical Center, Inc. | Integrated needle and test strip with aspiration apparatus and method of use |
| KR20140099403A (ko) * | 2013-02-01 | 2014-08-12 | 삼성전자주식회사 | 초음파 장치 및 그 제어 방법 |
| US20160008556A1 (en) * | 2014-07-10 | 2016-01-14 | Elwha Llc | Needle insertion system and method for inserting a movable needle into a vertebrate subject |
| CA2960260A1 (en) * | 2016-03-11 | 2017-09-11 | Arta Plast Ab | Safety injection needle device |
-
2014
- 2014-08-27 EP EP14839103.0A patent/EP3038680B1/en active Active
- 2014-08-27 JP JP2016537816A patent/JP6785157B2/ja active Active
- 2014-08-27 US US14/914,247 patent/US10278618B2/en active Active
- 2014-08-27 BR BR112016004124-0A patent/BR112016004124B1/pt active IP Right Grant
- 2014-08-27 CA CA2921971A patent/CA2921971C/en active Active
- 2014-08-27 WO PCT/US2014/052937 patent/WO2015031490A1/en not_active Ceased
- 2014-08-27 KR KR1020167007616A patent/KR102320331B1/ko active Active
- 2014-08-27 CN CN201480058753.6A patent/CN105682719B/zh active Active
Also Published As
| Publication number | Publication date |
|---|---|
| US10278618B2 (en) | 2019-05-07 |
| KR20160047518A (ko) | 2016-05-02 |
| EP3038680A1 (en) | 2016-07-06 |
| KR102320331B1 (ko) | 2021-11-03 |
| CN105682719A (zh) | 2016-06-15 |
| CA2921971A1 (en) | 2015-03-05 |
| JP2016529027A (ja) | 2016-09-23 |
| US20160213284A1 (en) | 2016-07-28 |
| BR112016004124A8 (pt) | 2020-02-11 |
| CA2921971C (en) | 2021-04-13 |
| CN105682719B (zh) | 2019-11-12 |
| EP3038680B1 (en) | 2021-02-24 |
| WO2015031490A1 (en) | 2015-03-05 |
| JP6785157B2 (ja) | 2020-11-18 |
| EP3038680A4 (en) | 2017-04-05 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B06U | Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette] | ||
| B06A | Patent application procedure suspended [chapter 6.1 patent gazette] | ||
| B09A | Decision: intention to grant [chapter 9.1 patent gazette] | ||
| B16A | Patent or certificate of addition of invention granted [chapter 16.1 patent gazette] |
Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 27/08/2014, OBSERVADAS AS CONDICOES LEGAIS |