BR112016003057A2 - composições e métodos para análise multimodal de ácidos nucleicos cmet - Google Patents
composições e métodos para análise multimodal de ácidos nucleicos cmetInfo
- Publication number
- BR112016003057A2 BR112016003057A2 BR112016003057A BR112016003057A BR112016003057A2 BR 112016003057 A2 BR112016003057 A2 BR 112016003057A2 BR 112016003057 A BR112016003057 A BR 112016003057A BR 112016003057 A BR112016003057 A BR 112016003057A BR 112016003057 A2 BR112016003057 A2 BR 112016003057A2
- Authority
- BR
- Brazil
- Prior art keywords
- primers
- cmet
- gene
- specific
- pairs
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 30
- 108020004707 nucleic acids Proteins 0.000 title abstract 6
- 150000007523 nucleic acids Chemical class 0.000 title abstract 6
- 102000039446 nucleic acids Human genes 0.000 title abstract 6
- 239000000203 mixture Substances 0.000 title 1
- 108091093088 Amplicon Proteins 0.000 abstract 38
- 108090000623 proteins and genes Proteins 0.000 abstract 28
- 238000003556 assay Methods 0.000 abstract 23
- 108091092584 GDNA Proteins 0.000 abstract 19
- 108060006698 EGF receptor Proteins 0.000 abstract 12
- 210000000349 chromosome Anatomy 0.000 abstract 10
- 108020004999 messenger RNA Proteins 0.000 abstract 10
- 101100203568 Halobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1) sod2 gene Proteins 0.000 abstract 9
- 101100111809 Schizosaccharomyces pombe (strain 972 / ATCC 24843) bsu1 gene Proteins 0.000 abstract 9
- 230000004075 alteration Effects 0.000 abstract 9
- 101150062190 sod1 gene Proteins 0.000 abstract 9
- 101150048620 sodN gene Proteins 0.000 abstract 9
- 239000011541 reaction mixture Substances 0.000 abstract 6
- 230000004544 DNA amplification Effects 0.000 abstract 5
- 101150024489 Spg21 gene Proteins 0.000 abstract 5
- 230000003321 amplification Effects 0.000 abstract 5
- 238000003199 nucleic acid amplification method Methods 0.000 abstract 5
- 238000012408 PCR amplification Methods 0.000 abstract 4
- 238000000137 annealing Methods 0.000 abstract 4
- 230000014509 gene expression Effects 0.000 abstract 4
- 238000000926 separation method Methods 0.000 abstract 4
- 101100065554 Dictyostelium discoideum kdelr gene Proteins 0.000 abstract 3
- 206010028980 Neoplasm Diseases 0.000 abstract 3
- 238000001514 detection method Methods 0.000 abstract 3
- 208000003609 Bile Duct Adenoma Diseases 0.000 abstract 2
- 208000003174 Brain Neoplasms Diseases 0.000 abstract 2
- 206010008342 Cervix carcinoma Diseases 0.000 abstract 2
- 206010009944 Colon cancer Diseases 0.000 abstract 2
- 101150039808 Egfr gene Proteins 0.000 abstract 2
- 208000008839 Kidney Neoplasms Diseases 0.000 abstract 2
- 206010058467 Lung neoplasm malignant Diseases 0.000 abstract 2
- 206010027406 Mesothelioma Diseases 0.000 abstract 2
- 208000034578 Multiple myelomas Diseases 0.000 abstract 2
- 206010033128 Ovarian cancer Diseases 0.000 abstract 2
- 206010061535 Ovarian neoplasm Diseases 0.000 abstract 2
- 206010035226 Plasma cell myeloma Diseases 0.000 abstract 2
- 206010038389 Renal cancer Diseases 0.000 abstract 2
- 206010039491 Sarcoma Diseases 0.000 abstract 2
- 208000024770 Thyroid neoplasm Diseases 0.000 abstract 2
- 208000006105 Uterine Cervical Neoplasms Diseases 0.000 abstract 2
- 101100065549 Xenopus laevis kdelr3 gene Proteins 0.000 abstract 2
- 201000010881 cervical cancer Diseases 0.000 abstract 2
- 238000006243 chemical reaction Methods 0.000 abstract 2
- 208000029742 colonic neoplasm Diseases 0.000 abstract 2
- 201000010536 head and neck cancer Diseases 0.000 abstract 2
- 208000014829 head and neck neoplasm Diseases 0.000 abstract 2
- 206010073071 hepatocellular carcinoma Diseases 0.000 abstract 2
- 201000010982 kidney cancer Diseases 0.000 abstract 2
- 201000005202 lung cancer Diseases 0.000 abstract 2
- 208000020816 lung neoplasm Diseases 0.000 abstract 2
- 201000001441 melanoma Diseases 0.000 abstract 2
- 208000002154 non-small cell lung carcinoma Diseases 0.000 abstract 2
- 201000002510 thyroid cancer Diseases 0.000 abstract 2
- 210000004881 tumor cell Anatomy 0.000 abstract 2
- 208000029729 tumor suppressor gene on chromosome 11 Diseases 0.000 abstract 2
- 208000005718 Stomach Neoplasms Diseases 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 206010017758 gastric cancer Diseases 0.000 abstract 1
- 230000002496 gastric effect Effects 0.000 abstract 1
- 201000011549 stomach cancer Diseases 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2527/00—Reactions demanding special reaction conditions
- C12Q2527/143—Concentration of primer or probe
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Analytical Chemistry (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Hospice & Palliative Care (AREA)
- Biophysics (AREA)
- Oncology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361865755P | 2013-08-14 | 2013-08-14 | |
| PCT/US2014/050076 WO2015023503A2 (en) | 2013-08-14 | 2014-08-07 | Compositions and methods for multimodal analysis of cmet nucleic acids |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR112016003057A2 true BR112016003057A2 (pt) | 2017-11-21 |
Family
ID=51358135
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112016003057A BR112016003057A2 (pt) | 2013-08-14 | 2014-08-07 | composições e métodos para análise multimodal de ácidos nucleicos cmet |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20160130660A1 (https=) |
| EP (1) | EP3033434A2 (https=) |
| JP (1) | JP2016527900A (https=) |
| KR (1) | KR20160106040A (https=) |
| CN (1) | CN105745335A (https=) |
| BR (1) | BR112016003057A2 (https=) |
| CA (1) | CA2917924A1 (https=) |
| SG (1) | SG11201600754PA (https=) |
| WO (1) | WO2015023503A2 (https=) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA3193811A1 (en) | 2014-11-14 | 2016-05-19 | Voyager Therapeutics, Inc. | Compositions and methods of treating amyotrophic lateral sclerosis (als) |
| JP7336091B2 (ja) * | 2016-08-02 | 2023-08-31 | 一般社団法人生命科学教育研究所 | 簡便な遺伝子検査法およびコピー数計測法ならびにその支援技術 |
| EP3618839A4 (en) | 2017-05-05 | 2021-06-09 | Voyager Therapeutics, Inc. | COMPOSITIONS AND METHODS OF TREATMENT OF AMYOTROPHIC LATERAL SCLEROSIS (ALS) |
| TW202413649A (zh) | 2017-10-16 | 2024-04-01 | 美商航海家醫療公司 | 肌萎縮性脊髓側索硬化症(als)之治療 |
| CN108893536B (zh) * | 2018-07-13 | 2022-02-15 | 江苏省人民医院（南京医科大学第一附属医院） | 一种从人外周血CTC中检测c-MET基因拷贝数变异的方法和试剂盒 |
| JP2021533769A (ja) * | 2018-08-16 | 2021-12-09 | ライフ テクノロジーズ コーポレーション | 核酸の増幅のための試薬、混合物、キット、および方法 |
| KR20210107492A (ko) * | 2020-02-24 | 2021-09-01 | (재)록원바이오융합연구재단 | 복제수 변이 검출용 표준화 유전자의 선별 방법 및 상기 방법에 의해서 선별된 c-Met 복제수 변이 검출용 조성물 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3756313B2 (ja) | 1997-03-07 | 2006-03-15 | 武 今西 | 新規ビシクロヌクレオシド及びオリゴヌクレオチド類縁体 |
| US7445893B2 (en) | 2002-04-12 | 2008-11-04 | Primera Biosystems, Inc. | Sampling method for amplification reaction analysis |
| US20070213292A1 (en) | 2005-08-10 | 2007-09-13 | The Rockefeller University | Chemically modified oligonucleotides for use in modulating micro RNA and uses thereof |
| WO2009061897A1 (en) | 2007-11-07 | 2009-05-14 | Primera Biosystems, Inc. | Quantification of nucleic acid molecules using multiplex pcr |
| EP2143441A1 (en) * | 2008-07-08 | 2010-01-13 | Pierre Fabre Medicament | Combination of a c-Met antagonist and an aminoheteroaryl compound for the treatment of cancer |
| PA8849001A1 (es) * | 2008-11-21 | 2010-06-28 | Lilly Co Eli | Anticuerpos de c-met |
| US9689028B2 (en) * | 2008-12-22 | 2017-06-27 | University Of Utah Foundation | Monochrome multiplex quantitative PCR |
| EP2656077A1 (en) * | 2010-12-23 | 2013-10-30 | Nestec S.A. | Drug selection for malignant cancer therapy using antibody-based arrays |
| WO2012119113A2 (en) * | 2011-03-02 | 2012-09-07 | Nestec Sa | Prediction of drug sensitivity of lung tumors based on molecular and genetic signatures |
-
2014
- 2014-08-07 JP JP2016534613A patent/JP2016527900A/ja active Pending
- 2014-08-07 EP EP14752755.0A patent/EP3033434A2/en not_active Withdrawn
- 2014-08-07 BR BR112016003057A patent/BR112016003057A2/pt active Search and Examination
- 2014-08-07 WO PCT/US2014/050076 patent/WO2015023503A2/en not_active Ceased
- 2014-08-07 KR KR1020167006476A patent/KR20160106040A/ko not_active Withdrawn
- 2014-08-07 US US14/897,323 patent/US20160130660A1/en not_active Abandoned
- 2014-08-07 SG SG11201600754PA patent/SG11201600754PA/en unknown
- 2014-08-07 CN CN201480056221.9A patent/CN105745335A/zh active Pending
- 2014-08-07 CA CA2917924A patent/CA2917924A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP3033434A2 (en) | 2016-06-22 |
| WO2015023503A2 (en) | 2015-02-19 |
| CA2917924A1 (en) | 2015-02-19 |
| CN105745335A (zh) | 2016-07-06 |
| SG11201600754PA (en) | 2016-02-26 |
| US20160130660A1 (en) | 2016-05-12 |
| WO2015023503A3 (en) | 2015-07-16 |
| JP2016527900A (ja) | 2016-09-15 |
| KR20160106040A (ko) | 2016-09-09 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 5A ANUIDADE. |