BR112016002462A8 - Métodos para melhorar os sintomas da asma usando benralizumabe - Google Patents
Métodos para melhorar os sintomas da asma usando benralizumabeInfo
- Publication number
- BR112016002462A8 BR112016002462A8 BR112016002462A BR112016002462A BR112016002462A8 BR 112016002462 A8 BR112016002462 A8 BR 112016002462A8 BR 112016002462 A BR112016002462 A BR 112016002462A BR 112016002462 A BR112016002462 A BR 112016002462A BR 112016002462 A8 BR112016002462 A8 BR 112016002462A8
- Authority
- BR
- Brazil
- Prior art keywords
- benralizumab
- asthma symptoms
- methods
- improve asthma
- improve
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2866—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pulmonology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
USO DE BENRALIZUMABE OU DE UM SEU FRAGMENTO DE LIGAÇÃO AO ANTÍGENO PARA MELHORAR OS SINTOMAS DA ASMA E BENRALIZUMABE OU UM SEU FRAGMENTO DE LIGAÇÃO AO ANTÍGENO PARA USO PARA MELHORAR OS SINTOMAS DA ASMA. Neste documento são conferidos métodos para melhorar os sintomas da asma, por exemplo, conforme medido por um questionário de controle de asma, compreendendo a administração ao paciente de uma quantidade eficaz de benralizumabe ou de um seu fragmento de ligação ao antígeno.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201361864950P | 2013-08-12 | 2013-08-12 | |
PCT/US2014/050122 WO2015023508A2 (en) | 2013-08-12 | 2014-08-07 | Methods for improving asthma symptoms using benralizumab |
Publications (2)
Publication Number | Publication Date |
---|---|
BR112016002462A2 BR112016002462A2 (pt) | 2017-09-12 |
BR112016002462A8 true BR112016002462A8 (pt) | 2018-06-12 |
Family
ID=52448839
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112016002462A BR112016002462A8 (pt) | 2013-08-12 | 2014-08-07 | Métodos para melhorar os sintomas da asma usando benralizumabe |
Country Status (18)
Country | Link |
---|---|
US (1) | US9441047B2 (pt) |
EP (3) | EP3033103B1 (pt) |
JP (2) | JP6803229B2 (pt) |
KR (1) | KR102337601B1 (pt) |
CN (2) | CN105451761A (pt) |
AU (3) | AU2014306960B2 (pt) |
BR (1) | BR112016002462A8 (pt) |
CA (1) | CA2918050C (pt) |
DK (2) | DK3536339T3 (pt) |
ES (2) | ES2740355T3 (pt) |
HK (2) | HK1221647A1 (pt) |
HU (2) | HUE045402T2 (pt) |
MX (1) | MX368474B (pt) |
PL (2) | PL3536339T3 (pt) |
RU (2) | RU2020123894A (pt) |
SG (1) | SG11201600484TA (pt) |
TR (1) | TR201910413T4 (pt) |
WO (1) | WO2015023508A2 (pt) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
RU2676333C2 (ru) * | 2013-08-12 | 2018-12-28 | Астразенека Аб | Способы снижения частоты приступов астмы с применением бенрализумаба |
SG11201600483QA (en) * | 2013-08-12 | 2016-02-26 | Medimmune Llc | Methods for increasing forced expiratory volume in asthmatics using benralizumab |
JP2016534996A (ja) * | 2013-10-15 | 2016-11-10 | メディミューン,エルエルシー | ベンラリズマブを使用して慢性閉塞性肺疾患を治療するための方法 |
JP2018538249A (ja) | 2015-11-04 | 2018-12-27 | アストラゼネカ アクチボラグ | 好酸球性疾患における好酸球標的化治療薬に対する臨床応答の予測変数としてのジペプチジルペプチダーゼ−4およびペリオスチン |
US20180056018A1 (en) * | 2016-08-31 | 2018-03-01 | Cephalon, Inc. | Inhalation Systems, Devices and Methods |
TW202214692A (zh) * | 2020-06-05 | 2022-04-16 | 瑞典商阿斯特捷利康公司 | 治療患有鼻瘜肉的患者的重度氣喘之方法 |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2205007C (en) | 1995-09-11 | 2010-12-14 | Masamichi Koike | Antibody against human interleukin-5 receptor .alpha. chain |
US6746839B1 (en) * | 1998-01-12 | 2004-06-08 | Interleukin Genetics, Inc. | Diagnostics and therapeutics for an obstructive airway disease |
ES2420835T3 (es) | 1999-04-09 | 2013-08-27 | Kyowa Hakko Kirin Co., Ltd. | Procedimiento para controlar la actividad de las moléculas inmunofuncionales |
CA2402477A1 (en) | 2000-02-15 | 2001-08-23 | Kyowa Hakko Kogyo Co., Ltd. | Eosinophil-specific apoptosis inducer |
US6946292B2 (en) | 2000-10-06 | 2005-09-20 | Kyowa Hakko Kogyo Co., Ltd. | Cells producing antibody compositions with increased antibody dependent cytotoxic activity |
US7662925B2 (en) | 2002-03-01 | 2010-02-16 | Xencor, Inc. | Optimized Fc variants and methods for their generation |
EP1688437A4 (en) | 2003-10-08 | 2007-09-26 | Kyowa Hakko Kogyo Kk | SPECIALLY BINDING ANTIBODY COMPOSITION TO IL-5 RECEPTOR |
US20060014680A1 (en) | 2004-07-13 | 2006-01-19 | Caiding Xu | Peptides and compounds that bind to the IL-5 receptor |
AU2006299429B2 (en) | 2005-10-03 | 2012-02-23 | Xencor, Inc. | Fc variants with optimized Fc receptor binding properties |
EP2068927B1 (en) * | 2007-05-14 | 2015-10-21 | MedImmune, LLC | Methods of reducing eosinophil levels |
KR101615474B1 (ko) * | 2010-12-16 | 2016-04-25 | 제넨테크, 인크. | Th2 억제에 관한 진단 및 치료 |
EP2710370A4 (en) * | 2011-05-18 | 2015-01-07 | Medimmune Llc | METHODS OF DIAGNOSING AND TREATING PULMONARY DISEASES OR DISORDERS |
WO2013066780A2 (en) | 2011-11-01 | 2013-05-10 | Medimmune, Llc | Methods for reducing the frequency and severity of acute exacerbations of asthma |
SG11201600483QA (en) * | 2013-08-12 | 2016-02-26 | Medimmune Llc | Methods for increasing forced expiratory volume in asthmatics using benralizumab |
RU2676333C2 (ru) * | 2013-08-12 | 2018-12-28 | Астразенека Аб | Способы снижения частоты приступов астмы с применением бенрализумаба |
-
2014
- 2014-08-07 JP JP2016534616A patent/JP6803229B2/ja active Active
- 2014-08-07 US US14/454,149 patent/US9441047B2/en active Active
- 2014-08-07 RU RU2020123894A patent/RU2020123894A/ru unknown
- 2014-08-07 EP EP14836392.2A patent/EP3033103B1/en active Active
- 2014-08-07 CN CN201480044052.7A patent/CN105451761A/zh active Pending
- 2014-08-07 HU HUE14836392A patent/HUE045402T2/hu unknown
- 2014-08-07 ES ES14836392T patent/ES2740355T3/es active Active
- 2014-08-07 BR BR112016002462A patent/BR112016002462A8/pt not_active Application Discontinuation
- 2014-08-07 ES ES19162585T patent/ES2901634T3/es active Active
- 2014-08-07 WO PCT/US2014/050122 patent/WO2015023508A2/en active Application Filing
- 2014-08-07 HU HUE19162585A patent/HUE057065T2/hu unknown
- 2014-08-07 PL PL19162585T patent/PL3536339T3/pl unknown
- 2014-08-07 DK DK19162585.4T patent/DK3536339T3/da active
- 2014-08-07 KR KR1020167006565A patent/KR102337601B1/ko active IP Right Grant
- 2014-08-07 PL PL14836392T patent/PL3033103T3/pl unknown
- 2014-08-07 CA CA2918050A patent/CA2918050C/en active Active
- 2014-08-07 EP EP21188229.5A patent/EP3988114A1/en not_active Withdrawn
- 2014-08-07 SG SG11201600484TA patent/SG11201600484TA/en unknown
- 2014-08-07 CN CN202010449449.1A patent/CN111617244A/zh active Pending
- 2014-08-07 AU AU2014306960A patent/AU2014306960B2/en active Active
- 2014-08-07 EP EP19162585.4A patent/EP3536339B1/en active Active
- 2014-08-07 RU RU2016108734A patent/RU2728578C2/ru active
- 2014-08-07 TR TR2019/10413T patent/TR201910413T4/tr unknown
- 2014-08-07 MX MX2016001195A patent/MX368474B/es active IP Right Grant
- 2014-08-07 DK DK14836392.2T patent/DK3033103T3/da active
-
2016
- 2016-08-16 HK HK16109789.8A patent/HK1221647A1/zh unknown
- 2016-12-01 HK HK16113685A patent/HK1225303A1/zh unknown
-
2020
- 2020-02-28 JP JP2020032499A patent/JP2020100653A/ja not_active Withdrawn
- 2020-04-16 AU AU2020202564A patent/AU2020202564A1/en not_active Abandoned
-
2023
- 2023-08-10 AU AU2023214323A patent/AU2023214323A1/en active Pending
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Legal Events
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B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
B25L | Entry of change of name and/or headquarter and transfer of application, patent and certificate of addition of invention: publication cancelled |
Owner name: ASTRAZENECA AB (SE) |
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B25L | Entry of change of name and/or headquarter and transfer of application, patent and certificate of addition of invention: publication cancelled |
Owner name: ASTRAZENECA AB (SE) |
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B25A | Requested transfer of rights approved |
Owner name: ASTRAZENECA AB (SE) |
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B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] |
Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI |
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B06U | Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette] | ||
B350 | Update of information on the portal [chapter 15.35 patent gazette] | ||
B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
B09B | Patent application refused [chapter 9.2 patent gazette] | ||
B09B | Patent application refused [chapter 9.2 patent gazette] |
Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL.MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL. |