BR112015026388A8 - uso de um composto de epoxi-tigliane, composto e composição farmacêutica - Google Patents

uso de um composto de epoxi-tigliane, composto e composição farmacêutica Download PDF

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Publication number
BR112015026388A8
BR112015026388A8 BR112015026388A BR112015026388A BR112015026388A8 BR 112015026388 A8 BR112015026388 A8 BR 112015026388A8 BR 112015026388 A BR112015026388 A BR 112015026388A BR 112015026388 A BR112015026388 A BR 112015026388A BR 112015026388 A8 BR112015026388 A8 BR 112015026388A8
Authority
BR
Brazil
Prior art keywords
compound
epoxy
tigliane
wound healing
pharmaceutical composition
Prior art date
Application number
BR112015026388A
Other languages
English (en)
Other versions
BR112015026388A2 (pt
Inventor
Mathew Boyle Glen
Warren Reddell Paul
Gordon Parsons Peter
Louise Moses Rachael
Steadman Robert
Moseley Ryan
Anne Gordon Victoria
Original Assignee
Qbiotics Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from AU2013901359A external-priority patent/AU2013901359A0/en
Application filed by Qbiotics Ltd filed Critical Qbiotics Ltd
Publication of BR112015026388A2 publication Critical patent/BR112015026388A2/pt
Publication of BR112015026388A8 publication Critical patent/BR112015026388A8/pt

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/38—Compounds containing oxirane rings with hydrocarbon radicals, substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D303/40—Compounds containing oxirane rings with hydrocarbon radicals, substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals by ester radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
    • A61K31/122—Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/336—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having three-membered rings, e.g. oxirane, fumagillin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/47—Euphorbiaceae (Spurge family), e.g. Ricinus (castorbean)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4973—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/32—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by aldehydo- or ketonic radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/10—Preparation or pretreatment of starting material
    • A61K2236/15—Preparation or pretreatment of starting material involving mechanical treatment, e.g. chopping up, cutting or grinding
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/74—Biological properties of particular ingredients

Abstract

resumo “métodos e composições para cicatrização de feridas” a presente invenção relaciona-se com compostos epoxi-tigliane e a sua utilização na promoção da cicatrização de feridas. em formas de realização particulares, os compostos epoxi-tigliane são compostos-3-ona-tigliaen epoxi. métodos de induzir ou promover a cicatrização de feridas, bem como métodos para reduzir a formação de cicatrizes e melhorando os resultados cosméticos sobre a cicatrização de uma ferida são descritos. os compostos e composições para uso na cicatrização de feridas também são descritos.
BR112015026388A 2013-04-18 2014-04-17 uso de um composto de epoxi-tigliane, composto e composição farmacêutica BR112015026388A8 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AU2013901359A AU2013901359A0 (en) 2013-04-18 Methods of Treatment
PCT/AU2014/050018 WO2014169356A1 (en) 2013-04-18 2014-04-17 Methods and compositions for wound healing

Publications (2)

Publication Number Publication Date
BR112015026388A2 BR112015026388A2 (pt) 2017-07-25
BR112015026388A8 true BR112015026388A8 (pt) 2019-12-31

Family

ID=51730618

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112015026388A BR112015026388A8 (pt) 2013-04-18 2014-04-17 uso de um composto de epoxi-tigliane, composto e composição farmacêutica

Country Status (30)

Country Link
US (3) US10183921B2 (pt)
EP (1) EP2986615B1 (pt)
JP (1) JP6415538B2 (pt)
KR (1) KR102147796B1 (pt)
CN (1) CN105308052B (pt)
AU (1) AU2014253608B2 (pt)
BR (1) BR112015026388A8 (pt)
CA (1) CA2909653C (pt)
CY (1) CY1121515T1 (pt)
DK (1) DK2986615T3 (pt)
EA (1) EA032501B9 (pt)
ES (1) ES2715105T3 (pt)
HK (1) HK1214256A1 (pt)
HR (1) HRP20190435T1 (pt)
HU (1) HUE043272T2 (pt)
IL (1) IL242137B (pt)
LT (1) LT2986615T (pt)
MX (1) MX365255B (pt)
MY (1) MY184372A (pt)
NZ (1) NZ713954A (pt)
PH (1) PH12015502405A1 (pt)
PL (1) PL2986615T3 (pt)
PT (1) PT2986615T (pt)
RS (1) RS58532B1 (pt)
SG (1) SG11201508588XA (pt)
SI (1) SI2986615T1 (pt)
TR (1) TR201903565T4 (pt)
UA (1) UA118670C2 (pt)
WO (1) WO2014169356A1 (pt)
ZA (1) ZA201508186B (pt)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10973858B2 (en) * 2016-02-12 2021-04-13 Laimu Corporation Nerve growth promoter and method for producing same, internal preparation, medium additive, cell dilution additive, medium, cell dilution, antioxidant and method for producing same, external preparation, and wound treatment agent and method for producing same
AU2017304228B2 (en) * 2016-07-28 2021-09-09 QBiotics Pty Ltd Method of treatment
KR102228055B1 (ko) 2017-03-23 2021-03-16 큐바이오틱스 피티와이 리미티드 종양의 치료 또는 예방을 위한 병용 요법
KR102249495B1 (ko) 2019-03-15 2021-06-01 주식회사 고위드 피부 관리 장치, 시스템 및 피부 관리 주기 결정 방법
CN113924091A (zh) 2019-04-12 2022-01-11 Q生物股份有限公司 治疗肿瘤的方法
US20220313648A1 (en) * 2019-06-19 2022-10-06 QBiotics Pty Ltd Biofilm disruption
CN112557541B (zh) * 2020-12-08 2022-07-12 河北科技大学 一种枸橼酸马罗匹坦及其有关物质的检测方法
WO2023115123A1 (en) * 2021-12-21 2023-06-29 QBiotics Pty Ltd Crystalline intermediates

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5641814A (en) * 1991-03-01 1997-06-24 Warner-Lambert Company Antikeratolytic-wound healing compositions and methods for preparing and using same
DE60138572D1 (de) * 2000-07-31 2009-06-10 Univ Bar Ilan Methoden und pharmazeutische zusammensetzungen zur wundheilung
JP2005230051A (ja) * 2004-02-17 2005-09-02 Nippon Riko Igaku Kenkyusho:Kk 電位治療器
WO2006026604A2 (en) 2004-08-27 2006-03-09 Advanced Viral Research Corp. Methods for promoting wound healing
ES2391296T3 (es) * 2005-12-23 2012-11-23 Qbiotics Limited Derivados de tiglien-3-ona
JP4785062B2 (ja) 2007-03-20 2011-10-05 日精樹脂工業株式会社 スクリュ加熱回路を備えた射出装置
AU2010200429A1 (en) 2009-02-05 2010-08-19 Ecobiotics Ltd Method of reducing or preventing blowfly strike
KR102030694B1 (ko) 2018-02-07 2019-11-18 엘지전자 주식회사 횡자속형 리니어 모터 및 이를 구비한 리니어 압축기

Also Published As

Publication number Publication date
US20190161462A1 (en) 2019-05-30
US10183922B2 (en) 2019-01-22
RS58532B1 (sr) 2019-04-30
TR201903565T4 (tr) 2019-04-22
CN105308052A (zh) 2016-02-03
EA032501B1 (ru) 2019-06-28
EA201591996A1 (ru) 2016-02-29
SI2986615T1 (sl) 2019-05-31
CY1121515T1 (el) 2020-05-29
AU2014253608A1 (en) 2015-11-26
UA118670C2 (uk) 2019-02-25
DK2986615T3 (en) 2019-04-01
JP6415538B2 (ja) 2018-10-31
PH12015502405B1 (en) 2016-02-22
US10822317B2 (en) 2020-11-03
EP2986615A1 (en) 2016-02-24
CA2909653C (en) 2022-04-12
ES2715105T3 (es) 2019-05-31
US10183921B2 (en) 2019-01-22
KR20160023651A (ko) 2016-03-03
HUE043272T2 (hu) 2019-08-28
MX365255B (es) 2019-05-28
HK1214256A1 (zh) 2016-07-22
IL242137B (en) 2019-03-31
MY184372A (en) 2021-04-01
NZ713954A (en) 2020-05-29
US20170144981A1 (en) 2017-05-25
EA032501B9 (ru) 2019-11-29
PL2986615T3 (pl) 2019-06-28
MX2015014607A (es) 2016-06-02
US20160068499A1 (en) 2016-03-10
JP2016522801A (ja) 2016-08-04
PH12015502405A1 (en) 2016-02-22
SG11201508588XA (en) 2015-11-27
WO2014169356A1 (en) 2014-10-23
EP2986615A4 (en) 2016-03-30
HRP20190435T1 (hr) 2019-05-03
KR102147796B1 (ko) 2020-08-26
CN105308052B (zh) 2018-07-10
ZA201508186B (en) 2019-08-28
CA2909653A1 (en) 2014-10-23
LT2986615T (lt) 2019-03-25
EP2986615B1 (en) 2018-12-12
PT2986615T (pt) 2019-03-22
BR112015026388A2 (pt) 2017-07-25
AU2014253608B2 (en) 2018-06-07

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B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]

Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI

B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B350 Update of information on the portal [chapter 15.35 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]