BR112015023387A2 - composições lipídicas de racecodotril - Google Patents
composições lipídicas de racecodotrilInfo
- Publication number
- BR112015023387A2 BR112015023387A2 BR112015023387A BR112015023387A BR112015023387A2 BR 112015023387 A2 BR112015023387 A2 BR 112015023387A2 BR 112015023387 A BR112015023387 A BR 112015023387A BR 112015023387 A BR112015023387 A BR 112015023387A BR 112015023387 A2 BR112015023387 A2 BR 112015023387A2
- Authority
- BR
- Brazil
- Prior art keywords
- racecodotril
- lipid compositions
- lipid
- racecadotril
- compositions
- Prior art date
Links
- 150000002632 lipids Chemical class 0.000 title abstract 3
- 239000000203 mixture Substances 0.000 title abstract 3
- 229960002281 racecadotril Drugs 0.000 abstract 2
- 108700040249 racecadotril Proteins 0.000 abstract 2
- ODUOJXZPIYUATO-UHFFFAOYSA-N 2-[[2-[(acetylthio)methyl]-1-oxo-3-phenylpropyl]amino]acetic acid (phenylmethyl) ester Chemical compound C=1C=CC=CC=1COC(=O)CNC(=O)C(CSC(=O)C)CC1=CC=CC=C1 ODUOJXZPIYUATO-UHFFFAOYSA-N 0.000 abstract 1
- -1 racecadotril lipid Chemical class 0.000 abstract 1
- 239000004094 surface-active agent Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/216—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A61K31/222—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin with compounds having aromatic groups, e.g. dipivefrine, ibopamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A61K31/223—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of alpha-aminoacids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/265—Esters, e.g. nitroglycerine, selenocyanates of carbonic, thiocarbonic, or thiocarboxylic acids, e.g. thioacetic acid, xanthogenic acid, trithiocarbonic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Emergency Medicine (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Dispersion Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- General Preparation And Processing Of Foods (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361787597P | 2013-03-15 | 2013-03-15 | |
| PCT/US2014/023903 WO2014150660A1 (en) | 2013-03-15 | 2014-03-12 | Racecadotril lipid compositions |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR112015023387A2 true BR112015023387A2 (pt) | 2017-07-18 |
Family
ID=50628914
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112015023387A BR112015023387A2 (pt) | 2013-03-15 | 2014-03-12 | composições lipídicas de racecodotril |
Country Status (15)
| Country | Link |
|---|---|
| US (2) | US9801819B2 (https=) |
| EP (1) | EP2968138B1 (https=) |
| JP (1) | JP2016512828A (https=) |
| KR (1) | KR20160101167A (https=) |
| CN (1) | CN105246460A (https=) |
| AU (2) | AU2014235733B2 (https=) |
| BR (1) | BR112015023387A2 (https=) |
| CA (2) | CA2907195A1 (https=) |
| IL (1) | IL241065A0 (https=) |
| MX (2) | MX2015012345A (https=) |
| PH (1) | PH12015502014A1 (https=) |
| RU (2) | RU2662069C2 (https=) |
| SA (1) | SA515361092B1 (https=) |
| WO (2) | WO2014150660A1 (https=) |
| ZA (1) | ZA201507661B (https=) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2866802B1 (en) | 2012-06-28 | 2016-07-27 | Johnson & Johnson Consumer Inc. | Racecadotril liquid compositions |
| US20150342882A1 (en) * | 2012-06-28 | 2015-12-03 | Johnson & Johnson Consumer Inc. | Methods of treatment using cadotril compositions |
| US9801819B2 (en) * | 2012-06-28 | 2017-10-31 | Johnson & Johnson Consumer Inc. | Racecadotril compositions |
| US9114171B2 (en) | 2012-06-28 | 2015-08-25 | Mcneil-Ppc, Inc. | Racecadotril liquid compositions |
| RU2632441C2 (ru) | 2012-06-28 | 2017-10-04 | МакНЕЙЛ-ППС, ИНК. | Липидные композиции рацекадотрила |
| JP2017500355A (ja) * | 2013-12-23 | 2017-01-05 | ジョンソン・アンド・ジョンソン・コンシューマー・インコーポレイテッド | ラセカドトリル組成物 |
| EP3503926B1 (en) * | 2016-08-23 | 2023-06-07 | Johnson & Johnson Consumer Inc. | New improved composition of racecadotril |
| EP3716954A1 (en) | 2017-11-27 | 2020-10-07 | Umecrine Cognition AB | Pharmaceutical formulation of 3 -ethynyl-3 -hydroxyandrostan-17-one oxime |
| BR112020016884A2 (pt) * | 2018-02-26 | 2020-12-15 | R.P. Scherer Technologies, Llc | Forma de dosagem farmacêutica para uma emulsão de simeticona e loperamida |
| CN114126587B (zh) * | 2019-07-08 | 2023-11-28 | 株式会社Moresco | 用于制备微型乳剂的组合物、微型乳剂、它们的制造方法、以及微型乳剂的应用 |
| US20230398102A1 (en) * | 2020-10-29 | 2023-12-14 | Bausch Health Ireland Limited | Rifaximin liquid formulations for use inthe treatment of sickle cell disease |
| WO2025212856A1 (en) * | 2024-04-05 | 2025-10-09 | The Board Of Regents Of The University Of Texas System | Microemulsion formulations |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2480747A1 (fr) | 1980-04-17 | 1981-10-23 | Roques Bernard | Derives d'acides amines et leur application therapeutique |
| US5136076A (en) | 1987-11-24 | 1992-08-04 | Societe Civile Bioprojet | Process for the preparation of amino acid-derived enatiomeric compounds |
| FR2623498B1 (fr) | 1987-11-24 | 1990-04-06 | Bioprojet Soc Civ | Nouveaux composes enantiomeres derives d'amino-acides, leur procede de preparation et leurs applications therapeutiques |
| SE9503143D0 (sv) * | 1995-09-12 | 1995-09-12 | Astra Ab | New preparation |
| WO1997033571A1 (fr) | 1996-03-14 | 1997-09-18 | Shionogi & Co., Ltd. | Preparation d'ecadotril a microdispersion et liberation rapides |
| CA2283780A1 (en) | 1997-03-12 | 1998-09-17 | Abbott Laboratories | Lipophilic binary systems for the administration of lipophilic compounds |
| GB9907715D0 (en) | 1999-04-01 | 1999-05-26 | Scherer Corp R P | Pharmaceutical compositions |
| GB0015490D0 (en) | 2000-06-23 | 2000-08-16 | Smithkline Beecham Lab | Novel formulations |
| DK1294372T3 (da) | 2000-06-23 | 2005-09-19 | Bioprojet Soc Civ | Törpulverformulering der omdanner racecadotril |
| EP1563848A1 (en) | 2004-02-12 | 2005-08-17 | Bioprojet | New combinations of an anti-emetic agent and an enkephalinase inhibitor |
| FR2900823B1 (fr) | 2006-05-15 | 2009-02-13 | Bioprojet Soc Civ Ile | Nouvelle forme d'administration du racecadotril. |
| CN101103960B (zh) | 2006-07-14 | 2010-12-08 | 海南盛科生命科学研究院 | 一种含有消旋卡多曲的干混悬剂及其制备方法 |
| CN101264065A (zh) | 2008-04-18 | 2008-09-17 | 盐城苏海制药有限公司 | 消旋卡多曲滴丸及其制备方法 |
| EP2496219A1 (en) | 2009-06-29 | 2012-09-12 | McNeil-PPC, Inc. | Pharmaceutical tablet containing a liquid filled capsule |
| CN102018707A (zh) * | 2010-11-29 | 2011-04-20 | 昆明邦宇制药有限公司 | 一种治疗腹泻的药物组合物及其制剂 |
| EP2462922A1 (en) | 2010-12-10 | 2012-06-13 | Bioprojet | New form of administration of enkephalinase inhibitor |
| CN102133186B (zh) | 2011-03-18 | 2012-08-01 | 海南美大制药有限公司 | 一种消旋卡多曲脂质体固体制剂 |
| CN102327234B (zh) | 2011-09-28 | 2017-04-12 | 海南康芝药业股份有限公司 | 一种消旋卡多曲干混悬剂 |
| EP2866802B1 (en) | 2012-06-28 | 2016-07-27 | Johnson & Johnson Consumer Inc. | Racecadotril liquid compositions |
| US9114171B2 (en) | 2012-06-28 | 2015-08-25 | Mcneil-Ppc, Inc. | Racecadotril liquid compositions |
| RU2632441C2 (ru) * | 2012-06-28 | 2017-10-04 | МакНЕЙЛ-ППС, ИНК. | Липидные композиции рацекадотрила |
| US9801819B2 (en) | 2012-06-28 | 2017-10-31 | Johnson & Johnson Consumer Inc. | Racecadotril compositions |
| US20150342882A1 (en) | 2012-06-28 | 2015-12-03 | Johnson & Johnson Consumer Inc. | Methods of treatment using cadotril compositions |
| TR201801726T4 (tr) | 2012-12-26 | 2018-03-21 | Ilko Ilac Sanayi Veticaret A S | Rasekadotri̇l ve farmasöti̇k bi̇leşi̇mleri̇. |
-
2013
- 2013-12-23 US US14/138,309 patent/US9801819B2/en active Active
-
2014
- 2014-03-12 CA CA2907195A patent/CA2907195A1/en not_active Abandoned
- 2014-03-12 AU AU2014235733A patent/AU2014235733B2/en not_active Expired - Fee Related
- 2014-03-12 BR BR112015023387A patent/BR112015023387A2/pt not_active Application Discontinuation
- 2014-03-12 CN CN201480015975.XA patent/CN105246460A/zh active Pending
- 2014-03-12 MX MX2015012345A patent/MX2015012345A/es unknown
- 2014-03-12 RU RU2015144013A patent/RU2662069C2/ru not_active IP Right Cessation
- 2014-03-12 WO PCT/US2014/023903 patent/WO2014150660A1/en not_active Ceased
- 2014-03-12 JP JP2016501378A patent/JP2016512828A/ja active Pending
- 2014-03-12 EP EP14720750.0A patent/EP2968138B1/en active Active
- 2014-03-12 US US14/205,565 patent/US9636300B2/en active Active
- 2014-12-22 KR KR1020167019811A patent/KR20160101167A/ko not_active Withdrawn
- 2014-12-22 CA CA2934816A patent/CA2934816A1/en not_active Abandoned
- 2014-12-22 WO PCT/US2014/071887 patent/WO2015100234A1/en not_active Ceased
- 2014-12-22 MX MX2016008390A patent/MX2016008390A/es unknown
- 2014-12-22 RU RU2016129907A patent/RU2016129907A/ru not_active Application Discontinuation
- 2014-12-22 AU AU2014370027A patent/AU2014370027A1/en not_active Abandoned
-
2015
- 2015-09-02 IL IL241065A patent/IL241065A0/en unknown
- 2015-09-09 PH PH12015502014A patent/PH12015502014A1/en unknown
- 2015-09-14 SA SA515361092A patent/SA515361092B1/ar unknown
- 2015-10-14 ZA ZA2015/07661A patent/ZA201507661B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| MX2016008390A (es) | 2017-01-11 |
| KR20160101167A (ko) | 2016-08-24 |
| ZA201507661B (en) | 2017-09-27 |
| AU2014370027A1 (en) | 2016-07-07 |
| PH12015502014A1 (en) | 2016-01-11 |
| WO2014150660A1 (en) | 2014-09-25 |
| EP2968138A1 (en) | 2016-01-20 |
| MX2015012345A (es) | 2017-03-27 |
| RU2662069C2 (ru) | 2018-07-23 |
| CN105246460A (zh) | 2016-01-13 |
| RU2016129907A (ru) | 2018-01-30 |
| SA515361092B1 (ar) | 2018-01-17 |
| AU2014235733A1 (en) | 2015-09-24 |
| CA2907195A1 (en) | 2014-09-25 |
| RU2016129907A3 (https=) | 2018-09-13 |
| US9801819B2 (en) | 2017-10-31 |
| US20140271832A1 (en) | 2014-09-18 |
| JP2016512828A (ja) | 2016-05-09 |
| EP2968138B1 (en) | 2018-08-15 |
| US20160331684A9 (en) | 2016-11-17 |
| AU2014235733B2 (en) | 2018-11-01 |
| US9636300B2 (en) | 2017-05-02 |
| WO2015100234A1 (en) | 2015-07-02 |
| RU2015144013A (ru) | 2017-04-28 |
| IL241065A0 (en) | 2015-11-30 |
| US20140275246A1 (en) | 2014-09-18 |
| CA2934816A1 (en) | 2015-07-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
| B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] | ||
| B06U | Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette] | ||
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 6A ANUIDADE. |
|
| B11B | Dismissal acc. art. 36, par 1 of ipl - no reply within 90 days to fullfil the necessary requirements |