BR112015021212A2 - fórmula de nanocompósitos com base de ferro para tratamento rápido e eficiente de anemia ferropriva - Google Patents
fórmula de nanocompósitos com base de ferro para tratamento rápido e eficiente de anemia ferroprivaInfo
- Publication number
- BR112015021212A2 BR112015021212A2 BR112015021212A BR112015021212A BR112015021212A2 BR 112015021212 A2 BR112015021212 A2 BR 112015021212A2 BR 112015021212 A BR112015021212 A BR 112015021212A BR 112015021212 A BR112015021212 A BR 112015021212A BR 112015021212 A2 BR112015021212 A2 BR 112015021212A2
- Authority
- BR
- Brazil
- Prior art keywords
- iron
- nanocomposite
- vitamin
- nanocomposites
- deficiency anemia
- Prior art date
Links
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 title abstract 16
- 239000002114 nanocomposite Substances 0.000 title abstract 9
- 229910052742 iron Inorganic materials 0.000 title abstract 8
- 208000015710 Iron-Deficiency Anemia Diseases 0.000 title abstract 4
- UQSXHKLRYXJYBZ-UHFFFAOYSA-N Iron oxide Chemical compound [Fe]=O UQSXHKLRYXJYBZ-UHFFFAOYSA-N 0.000 abstract 4
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 abstract 3
- 102000001554 Hemoglobins Human genes 0.000 abstract 3
- 108010054147 Hemoglobins Proteins 0.000 abstract 3
- OVBPIULPVIDEAO-LBPRGKRZSA-N folic acid Chemical compound C=1N=C2NC(N)=NC(=O)C2=NC=1CNC1=CC=C(C(=O)N[C@@H](CCC(O)=O)C(O)=O)C=C1 OVBPIULPVIDEAO-LBPRGKRZSA-N 0.000 abstract 3
- PVNIIMVLHYAWGP-UHFFFAOYSA-N Niacin Chemical compound OC(=O)C1=CC=CN=C1 PVNIIMVLHYAWGP-UHFFFAOYSA-N 0.000 abstract 2
- 229960005070 ascorbic acid Drugs 0.000 abstract 2
- 230000037396 body weight Effects 0.000 abstract 2
- 210000001185 bone marrow Anatomy 0.000 abstract 2
- -1 iron oxide vitamin Chemical class 0.000 abstract 2
- 229940088594 vitamin Drugs 0.000 abstract 2
- 235000013343 vitamin Nutrition 0.000 abstract 2
- 239000011782 vitamin Substances 0.000 abstract 2
- 229930003231 vitamin Natural products 0.000 abstract 2
- OVBPIULPVIDEAO-UHFFFAOYSA-N N-Pteroyl-L-glutaminsaeure Natural products C=1N=C2NC(N)=NC(=O)C2=NC=1CNC1=CC=C(C(=O)NC(CCC(O)=O)C(O)=O)C=C1 OVBPIULPVIDEAO-UHFFFAOYSA-N 0.000 abstract 1
- 238000010521 absorption reaction Methods 0.000 abstract 1
- 208000007502 anemia Diseases 0.000 abstract 1
- 239000007864 aqueous solution Substances 0.000 abstract 1
- 235000010323 ascorbic acid Nutrition 0.000 abstract 1
- 239000011668 ascorbic acid Substances 0.000 abstract 1
- 239000002775 capsule Substances 0.000 abstract 1
- 239000002552 dosage form Substances 0.000 abstract 1
- 210000003743 erythrocyte Anatomy 0.000 abstract 1
- 229960000304 folic acid Drugs 0.000 abstract 1
- 235000019152 folic acid Nutrition 0.000 abstract 1
- 239000011724 folic acid Substances 0.000 abstract 1
- 230000002489 hematologic effect Effects 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 229940031182 nanoparticles iron oxide Drugs 0.000 abstract 1
- 229960003512 nicotinic acid Drugs 0.000 abstract 1
- 235000001968 nicotinic acid Nutrition 0.000 abstract 1
- 239000011664 nicotinic acid Substances 0.000 abstract 1
- 239000002243 precursor Substances 0.000 abstract 1
- 230000001988 toxicity Effects 0.000 abstract 1
- 231100000419 toxicity Toxicity 0.000 abstract 1
- 231100000041 toxicology testing Toxicity 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/26—Iron; Compounds thereof
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/15—Vitamins
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/16—Inorganic salts, minerals or trace elements
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
- A61K31/375—Ascorbic acid, i.e. vitamin C; Salts thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/455—Nicotinic acids, e.g. niacin; Derivatives thereof, e.g. esters, amides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
- A61K9/5107—Excipients; Inactive ingredients
- A61K9/5115—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Inorganic Chemistry (AREA)
- Nutrition Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Polymers & Plastics (AREA)
- Mycology (AREA)
- Food Science & Technology (AREA)
- Physiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Physics & Mathematics (AREA)
- Biomedical Technology (AREA)
- Nanotechnology (AREA)
- Optics & Photonics (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EG2013030371 | 2013-03-06 | ||
| PCT/EG2013/000027 WO2014135170A1 (en) | 2013-03-06 | 2013-10-29 | Novel formula of iron based nanocomposites for rapid and efficient treatment of iron deficiency anemia |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR112015021212A2 true BR112015021212A2 (pt) | 2017-07-18 |
Family
ID=51490651
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112015021212A BR112015021212A2 (pt) | 2013-03-06 | 2013-10-29 | fórmula de nanocompósitos com base de ferro para tratamento rápido e eficiente de anemia ferropriva |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20160022733A1 (https=) |
| EP (1) | EP2964205A4 (https=) |
| JP (1) | JP2016511261A (https=) |
| CN (1) | CN105101957A (https=) |
| BR (1) | BR112015021212A2 (https=) |
| WO (1) | WO2014135170A1 (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR102085115B1 (ko) * | 2017-07-21 | 2020-03-05 | 스노우화이트팩토리(주) | 마그헤마이트-사포닌 나노결합체를 유효성분으로 함유하는 조혈기능 장애 질환 예방 또는 치료용 약학조성물 |
| CN109602914B (zh) * | 2019-01-08 | 2022-05-17 | 扬州大学 | 维生素b2修饰的铁基纳米酶及其制备方法和应用 |
| WO2024100213A1 (fr) | 2022-11-10 | 2024-05-16 | Université De Lorraine | Nanoclusters de fer, leurs procédés d'obtention et leurs utilisations pour lutter contre les carences en fer |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7585527B2 (en) * | 2005-09-19 | 2009-09-08 | Bala Venkataraman | Composition and method for treating iron deficiency anemia |
| TWI321133B (en) * | 2006-08-01 | 2010-03-01 | Univ Kaohsiung Medical | Folate-receptor-targeting iron oxide nanoparticles coated with poly(ethylene glycol) |
| JP4793202B2 (ja) * | 2006-09-27 | 2011-10-12 | 大日本印刷株式会社 | 壁紙 |
| WO2009120702A2 (en) * | 2008-03-25 | 2009-10-01 | Emory University | Elemental iron nanoparticles |
| WO2010034319A1 (en) * | 2008-09-29 | 2010-04-01 | Innovative Research And Development Co. (Inrad) | Magnetite nanoparticles as a single dose treatment for iron deficiency anemia |
| WO2012092305A2 (en) * | 2010-12-27 | 2012-07-05 | Incube Labs, Llc | Nanonized iron compositions and methods of use thereof |
| CN102730767B (zh) * | 2012-06-13 | 2014-05-21 | 湖北工业大学 | 一种纳米α-氧化铁粉体的快速制备方法 |
-
2013
- 2013-10-29 JP JP2015560555A patent/JP2016511261A/ja active Pending
- 2013-10-29 US US14/772,648 patent/US20160022733A1/en not_active Abandoned
- 2013-10-29 BR BR112015021212A patent/BR112015021212A2/pt not_active IP Right Cessation
- 2013-10-29 WO PCT/EG2013/000027 patent/WO2014135170A1/en not_active Ceased
- 2013-10-29 CN CN201380074286.1A patent/CN105101957A/zh active Pending
- 2013-10-29 EP EP13876801.5A patent/EP2964205A4/en not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| EP2964205A1 (en) | 2016-01-13 |
| US20160022733A1 (en) | 2016-01-28 |
| WO2014135170A1 (en) | 2014-09-12 |
| CN105101957A (zh) | 2015-11-25 |
| JP2016511261A (ja) | 2016-04-14 |
| EP2964205A4 (en) | 2016-07-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] | ||
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |