BR112015010498A2 - sistemas e métodos para contagem de plaquetas com ajuste de aglomerações - Google Patents

sistemas e métodos para contagem de plaquetas com ajuste de aglomerações

Info

Publication number
BR112015010498A2
BR112015010498A2 BR112015010498A BR112015010498A BR112015010498A2 BR 112015010498 A2 BR112015010498 A2 BR 112015010498A2 BR 112015010498 A BR112015010498 A BR 112015010498A BR 112015010498 A BR112015010498 A BR 112015010498A BR 112015010498 A2 BR112015010498 A2 BR 112015010498A2
Authority
BR
Brazil
Prior art keywords
methods
systems
platelet
cluster adjustment
platelet counting
Prior art date
Application number
BR112015010498A
Other languages
English (en)
Other versions
BR112015010498B1 (pt
Inventor
Lu Jiuliu
Riley John
Rossman Mark
Zhang Shuliang
Original Assignee
Beckman Coulter Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beckman Coulter Inc filed Critical Beckman Coulter Inc
Publication of BR112015010498A2 publication Critical patent/BR112015010498A2/pt
Publication of BR112015010498B1 publication Critical patent/BR112015010498B1/pt

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483Physical analysis of biological material
    • G01N33/487Physical analysis of biological material of liquid biological material
    • G01N33/49Blood
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N15/1031Investigating individual particles by measuring electrical or magnetic effects thereof, e.g. conductivity or capacity
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N15/12Coulter-counters
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N15/14Electro-optical investigation, e.g. flow cytometers
    • G01N15/1456Electro-optical investigation, e.g. flow cytometers without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals
    • G01N15/1459Electro-optical investigation, e.g. flow cytometers without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals the analysis being performed on a sample stream
    • G01N2015/018
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N2015/1006Investigating individual particles for cytology
    • G01N2015/1019
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N15/14Electro-optical investigation, e.g. flow cytometers
    • G01N2015/1402Data analysis by thresholding or gating operations performed on the acquired signals or stored data
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N15/14Electro-optical investigation, e.g. flow cytometers
    • G01N2015/1486Counting the particles
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N15/14Electro-optical investigation, e.g. flow cytometers
    • G01N2015/1493Particle size
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483Physical analysis of biological material
    • G01N33/487Physical analysis of biological material of liquid biological material
    • G01N33/49Blood
    • G01N33/4915Blood using flow cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Engineering & Computer Science (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • General Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Dispersion Chemistry (AREA)
  • Hematology (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Ecology (AREA)
  • Biophysics (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Optical Measuring Cells (AREA)

Abstract

resumo patente de invenção: "sistemas e métodos para contagem de plaquetas com ajuste de aglomerações". as modalidades da presente invenção abrangem sistemas e métodos automatizados para analisar os parâmetros das plaquetas em um indivíduo com base em uma amostra biológica obtida a partir do sangue do indivíduo. as técnicas exemplificadoras envolvem correlacionar aspectos de dados da impedância de corrente contínua (cc) e/ou de medição de luz obtidos a partir da amostra biológica com uma avaliação das condições das plaquetas no indivíduo.
BR112015010498-3A 2012-12-31 2013-12-31 Sistema de hematologia para determinar uma contagem de plaquetas em uma amostra biológica, e método automatizado para determinar uma contagem de plaquetas em uma amostra biológica BR112015010498B1 (pt)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201261747655P 2012-12-31 2012-12-31
US61/747,655 2012-12-31
US14/145,608 US9176112B2 (en) 2012-12-31 2013-12-31 Systems and methods for platelet count with clump adjustment
PCT/US2013/078543 WO2014106270A1 (en) 2012-12-31 2013-12-31 Systems and methods for platelet count with clump adjustment
US14/145,608 2013-12-31

Publications (2)

Publication Number Publication Date
BR112015010498A2 true BR112015010498A2 (pt) 2017-07-11
BR112015010498B1 BR112015010498B1 (pt) 2020-09-29

Family

ID=51016868

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112015010498-3A BR112015010498B1 (pt) 2012-12-31 2013-12-31 Sistema de hematologia para determinar uma contagem de plaquetas em uma amostra biológica, e método automatizado para determinar uma contagem de plaquetas em uma amostra biológica

Country Status (9)

Country Link
US (1) US9176112B2 (pt)
EP (1) EP2939001B1 (pt)
JP (2) JP6427108B2 (pt)
KR (1) KR101991989B1 (pt)
CN (1) CN104755905B (pt)
BR (1) BR112015010498B1 (pt)
ES (1) ES2772453T3 (pt)
IN (1) IN2015DN02927A (pt)
WO (1) WO2014106270A1 (pt)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9612221B2 (en) * 2014-10-14 2017-04-04 Chem-Aqua, Inc. + Pyxis Lab, Inc. Opto-electrochemical sensing system for monitoring and controlling industrial fluids
WO2017171762A1 (en) 2016-03-30 2017-10-05 Siemens Healthcare Diagnostics Inc. Systems, methods, and apparatus for processing platelet cell data
KR101895760B1 (ko) * 2016-06-27 2018-09-06 (주)뉴옵틱스 혈구 분석 시스템 및 그의 제어방법
JP7134184B2 (ja) * 2017-05-25 2022-09-09 アボット・ラボラトリーズ 試料分析のための方法およびシステム
MX2021013666A (es) * 2019-05-09 2022-01-24 Truvian Sciences Inc Métodos y composiciones para revertir la acumulacion de plaquetas.
WO2020248138A1 (zh) * 2019-06-11 2020-12-17 深圳迈瑞生物医疗电子股份有限公司 样本检测方法及样本分析仪
CN112683743B (zh) * 2021-03-12 2021-06-18 杭州晟视科技有限公司 血小板状态分析方法、装置、电子设备和存储介质

Family Cites Families (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4325706A (en) * 1980-08-15 1982-04-20 Ortho Diagnostic Systems Inc. Automated detection of platelets and reticulocytes in whole blood
KR970007077B1 (ko) 1987-03-13 1997-05-02 코울터 일렉트로닉스 인커퍼레이티드 광산란 기술을 이용한 다중-부분식별 분석 방법
US5540494A (en) * 1994-06-03 1996-07-30 Purvis, Jr.; Norman B. Method and apparatus for determining absolute particle size, surface area and volume normalized fluorescence using forward angle light scatter intensity in flow cytometry
US5891734A (en) * 1994-08-01 1999-04-06 Abbott Laboratories Method for performing automated analysis
US6025201A (en) 1995-12-28 2000-02-15 Bayer Corporation Highly sensitive, accurate, and precise automated method and device for identifying and quantifying platelets and for determining platelet activation state using whole blood samples
US6133995A (en) 1997-05-09 2000-10-17 Sysmex Corporation Particle measuring apparatus
JP4817270B2 (ja) * 1997-05-13 2011-11-16 シスメックス株式会社 粒子測定装置
US6235536B1 (en) * 1998-03-07 2001-05-22 Robert A. Levine Analysis of quiescent anticoagulated whole blood samples
US6228652B1 (en) 1999-02-16 2001-05-08 Coulter International Corp. Method and apparatus for analyzing cells in a whole blood sample
AU2002333589A1 (en) 2001-09-12 2003-03-24 Burstein Technologies, Inc. Methods for differential cell counts including related apparatus and software for performing same
US20050214758A1 (en) * 2001-12-11 2005-09-29 Netech Inc. Blood cell separating system
AU2003284534A1 (en) * 2002-12-02 2004-06-23 Asahi Medical Co., Ltd. Method of removing leukocytes, leukocyte-removing filter and utilization thereof
US7008792B2 (en) * 2004-02-10 2006-03-07 Beckman Coulter, Inc. Method of measurement of nucleated red blood cells
US7208319B2 (en) * 2004-02-10 2007-04-24 Beckman Coulter, Inc. Method of measurement of nucleated red blood cells
US7390662B2 (en) 2005-11-09 2008-06-24 Beckman Coulter, Inc. Method and apparatus for performing platelet measurement
US7796797B2 (en) 2005-09-28 2010-09-14 Sysmex Corporation Apparatus for obtaining an image of a blood cell and method for obtaining an image of a blood cell
US7344890B2 (en) 2005-11-09 2008-03-18 Beckman Coulter, Inc. Method for discriminating platelets from red blood cells
JP4976038B2 (ja) * 2006-03-29 2012-07-18 シスメックス株式会社 血液学的試料の測定方法
US8293524B2 (en) 2006-03-31 2012-10-23 Fluxion Biosciences Inc. Methods and apparatus for the manipulation of particle suspensions and testing thereof
JP4829716B2 (ja) * 2006-08-18 2011-12-07 シスメックス株式会社 血液凝固分析装置
US7674622B2 (en) * 2006-12-22 2010-03-09 Abbott Laboratories, Inc. Method for determination of nucleated red blood cells and leukocytes in a whole blood sample in an automated hematology analyzer
EP2215219A4 (en) 2007-10-29 2011-04-13 Beckman Coulter Inc METHOD FOR RAPID ANALYSIS BASED ON ANTIBODIES OF POPULATIONS OF PLATELETS
EP2271937B1 (en) * 2008-03-21 2016-01-13 Abbott Point Of Care, Inc. Method and apparatus for detecting and counting platelets individually and in aggregate clumps
US8094299B2 (en) 2008-07-24 2012-01-10 Beckman Coulter, Inc. Transducer module
AU2009280612B2 (en) * 2008-08-11 2014-11-13 Fujimori Kogyo Co., Ltd. Blood-platelet test method and blood-platelet test device
US8417012B2 (en) 2008-11-04 2013-04-09 Beckman Coulter, Inc. Non-linear histogram segmentation for particle analysis
WO2010056859A1 (en) 2008-11-14 2010-05-20 Beckman Coulter, Inc. Monolithic optical flow cells and method of manufacture
JP5464553B2 (ja) * 2010-12-21 2014-04-09 興和株式会社 凝集反応測定方法、および凝集反応測定装置
AU2012242587B2 (en) * 2011-04-15 2015-11-26 Roche Diagnostics Hematology, Inc. Measuring volume and constituents of cells

Also Published As

Publication number Publication date
WO2014106270A1 (en) 2014-07-03
US9176112B2 (en) 2015-11-03
US20140185031A1 (en) 2014-07-03
KR20150100634A (ko) 2015-09-02
CN104755905A (zh) 2015-07-01
EP2939001B1 (en) 2019-12-04
JP2016508224A (ja) 2016-03-17
ES2772453T3 (es) 2020-07-07
BR112015010498B1 (pt) 2020-09-29
JP6427108B2 (ja) 2018-11-21
CN104755905B (zh) 2018-07-03
IN2015DN02927A (pt) 2015-09-18
KR101991989B1 (ko) 2019-06-21
JP2018077247A (ja) 2018-05-17
EP2939001A1 (en) 2015-11-04

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Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 31/12/2013, OBSERVADAS AS CONDICOES LEGAIS.