BR112015001052A2 - - Google Patents
Info
- Publication number
- BR112015001052A2 BR112015001052A2 BR112015001052A BR112015001052A BR112015001052A2 BR 112015001052 A2 BR112015001052 A2 BR 112015001052A2 BR 112015001052 A BR112015001052 A BR 112015001052A BR 112015001052 A BR112015001052 A BR 112015001052A BR 112015001052 A2 BR112015001052 A2 BR 112015001052A2
- Authority
- BR
- Brazil
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6869—Methods for sequencing
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y306/00—Hydrolases acting on acid anhydrides (3.6)
- C12Y306/04—Hydrolases acting on acid anhydrides (3.6) acting on acid anhydrides; involved in cellular and subcellular movement (3.6.4)
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biophysics (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Peptides Or Proteins (AREA)
- Enzymes And Modification Thereof (AREA)
- Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201261673446P | 2012-07-19 | 2012-07-19 | |
US61/673,446 | 2012-07-19 | ||
US201361774694P | 2013-03-08 | 2013-03-08 | |
US61/774,694 | 2013-03-08 | ||
PCT/GB2013/051928 WO2014013262A1 (en) | 2012-07-19 | 2013-07-18 | Enzyme construct |
Publications (3)
Publication Number | Publication Date |
---|---|
BR112015001052A2 true BR112015001052A2 (pt) | 2017-08-15 |
BR112015001052B1 BR112015001052B1 (pt) | 2022-04-05 |
BR112015001052B8 BR112015001052B8 (pt) | 2022-12-27 |
Family
ID=48874433
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112015001052A BR112015001052B8 (pt) | 2012-07-19 | 2013-07-18 | Métodos para distinguir um polinucleotídeo alvo,sensor para distinguir um polinucleotídeo alvo, e, uso de um construto |
Country Status (7)
Country | Link |
---|---|
US (2) | US9797009B2 (pt) |
EP (1) | EP2875152B1 (pt) |
JP (2) | JP6429773B2 (pt) |
AU (1) | AU2013291765C1 (pt) |
BR (1) | BR112015001052B8 (pt) |
CA (1) | CA2879355C (pt) |
WO (1) | WO2014013262A1 (pt) |
Families Citing this family (76)
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EP2122344B8 (en) | 2007-02-20 | 2019-08-21 | Oxford Nanopore Technologies Limited | Lipid bilayer sensor system |
GB0724736D0 (en) | 2007-12-19 | 2008-01-30 | Oxford Nanolabs Ltd | Formation of layers of amphiphilic molecules |
AU2010209528B2 (en) | 2009-01-30 | 2015-10-01 | Oxford Nanopore Technologies Limited | Adaptors for nucleic acid constructs in transmembrane sequencing |
SG10201604316WA (en) | 2011-05-27 | 2016-07-28 | Oxford Nanopore Tech Ltd | Coupling method |
AU2012288629B2 (en) | 2011-07-25 | 2017-02-02 | Oxford Nanopore Technologies Limited | Hairpin loop method for double strand polynucleotide sequencing using transmembrane pores |
US9758823B2 (en) | 2011-10-21 | 2017-09-12 | Oxford Nanopore Technologies Limited | Enzyme method |
KR20130049671A (ko) | 2011-11-04 | 2013-05-14 | 한미사이언스 주식회사 | 생리활성 폴리펩타이드 결합체 제조 방법 |
EP2798083B1 (en) | 2011-12-29 | 2017-08-09 | Oxford Nanopore Technologies Limited | Method for characterising a polynucelotide by using a xpd helicase |
US10385382B2 (en) | 2011-12-29 | 2019-08-20 | Oxford Nanopore Technologies Ltd. | Enzyme method |
GB201202519D0 (en) | 2012-02-13 | 2012-03-28 | Oxford Nanopore Tech Ltd | Apparatus for supporting an array of layers of amphiphilic molecules and method of forming an array of layers of amphiphilic molecules |
CA2864035C (en) | 2012-02-15 | 2021-05-18 | Oxford Nanopore Technologies Limited | A method for determining the presence of an analyte using an aptamer |
BR112014020211A2 (pt) | 2012-02-16 | 2017-07-04 | Oxford Nanopore Tech Ltd | métodos para analisar uma série ordenada por tempo de medições de um polímero, para estimar a presença, ausência ou quantidade de um polímero alvo, e para determinar uma alteração em um polímero, programa de computador, e, dispositivos de análise e de diagnóstico |
AR090281A1 (es) | 2012-03-08 | 2014-10-29 | Hanmi Science Co Ltd | Proceso mejorado para la preparacion de un complejo polipeptidico fisiologicamente activo |
WO2013153359A1 (en) | 2012-04-10 | 2013-10-17 | Oxford Nanopore Technologies Limited | Mutant lysenin pores |
EP2875128B8 (en) | 2012-07-19 | 2020-06-24 | Oxford Nanopore Technologies Limited | Modified helicases |
EP2875152B1 (en) | 2012-07-19 | 2019-10-09 | Oxford Nanopore Technologies Limited | Enzyme construct |
EP2875154B1 (en) | 2012-07-19 | 2017-08-23 | Oxford Nanopore Technologies Limited | SSB method for characterising a nucleic acid |
WO2014041337A1 (en) | 2012-09-14 | 2014-03-20 | Oxford Nanopore Technologies Limited | Sample preparation method |
GB201313121D0 (en) | 2013-07-23 | 2013-09-04 | Oxford Nanopore Tech Ltd | Array of volumes of polar medium |
EP2917366B1 (en) | 2012-11-06 | 2017-08-02 | Oxford Nanopore Technologies Limited | Quadruplex method |
GB201222928D0 (en) | 2012-12-19 | 2013-01-30 | Oxford Nanopore Tech Ltd | Analysis of a polynucleotide |
GB201318465D0 (en) | 2013-10-18 | 2013-12-04 | Oxford Nanopore Tech Ltd | Method |
JP6408494B2 (ja) | 2013-03-08 | 2018-10-17 | オックスフォード ナノポール テクノロジーズ リミテッド | 酵素停止法 |
GB201314695D0 (en) | 2013-08-16 | 2013-10-02 | Oxford Nanopore Tech Ltd | Method |
GB201313477D0 (en) | 2013-07-29 | 2013-09-11 | Univ Leuven Kath | Nanopore biosensors for detection of proteins and nucleic acids |
GB201406151D0 (en) * | 2014-04-04 | 2014-05-21 | Oxford Nanopore Tech Ltd | Method |
CN117947149A (zh) | 2013-10-18 | 2024-04-30 | 牛津纳米孔科技公开有限公司 | 经修饰的酶 |
AU2015208919B9 (en) | 2014-01-22 | 2021-04-01 | Oxford Nanopore Technologies Limited | Method for attaching one or more polynucleotide binding proteins to a target polynucleotide |
GB201406155D0 (en) | 2014-04-04 | 2014-05-21 | Oxford Nanopore Tech Ltd | Method |
GB201403096D0 (en) | 2014-02-21 | 2014-04-09 | Oxford Nanopore Tech Ltd | Sample preparation method |
CN117065044A (zh) * | 2014-03-31 | 2023-11-17 | 韩美药品株式会社 | 通过使用免疫球蛋白Fc片段连接改善蛋白质和肽的溶解度的方法 |
CN106460061B (zh) | 2014-04-04 | 2020-03-06 | 牛津纳米孔技术公司 | 在双链核酸分子的两端使用纳米孔和锚分子来表征所述双链核酸的方法 |
GB201417712D0 (en) | 2014-10-07 | 2014-11-19 | Oxford Nanopore Tech Ltd | Method |
WO2015166276A1 (en) * | 2014-05-02 | 2015-11-05 | Oxford Nanopore Technologies Limited | Method of improving the movement of a target polynucleotide with respect to a transmembrane pore |
WO2016034591A2 (en) | 2014-09-01 | 2016-03-10 | Vib Vzw | Mutant pores |
WO2016055778A1 (en) | 2014-10-07 | 2016-04-14 | Oxford Nanopore Technologies Limited | Mutant pores |
GB201418159D0 (en) | 2014-10-14 | 2014-11-26 | Oxford Nanopore Tech Ltd | Method |
US10689697B2 (en) | 2014-10-16 | 2020-06-23 | Oxford Nanopore Technologies Ltd. | Analysis of a polymer |
JP6824881B2 (ja) | 2014-10-17 | 2021-02-03 | オックスフォード ナノポール テクノロジーズ リミテッド | ナノ細孔rnaを特徴付けるための方法 |
GB201418469D0 (en) | 2014-10-17 | 2014-12-03 | Oxford Nanopore Tech Ltd | Method |
GB201418512D0 (en) | 2014-10-17 | 2014-12-03 | Oxford Nanopore Tech Ltd | Electrical device with detachable components |
GB201502810D0 (en) | 2015-02-19 | 2015-04-08 | Oxford Nanopore Tech Ltd | Method |
GB201502809D0 (en) | 2015-02-19 | 2015-04-08 | Oxford Nanopore Tech Ltd | Mutant pore |
WO2016166232A1 (en) | 2015-04-14 | 2016-10-20 | Katholieke Universiteit Leuven | Nanopores with internal protein adaptors |
US10280411B2 (en) | 2015-10-27 | 2019-05-07 | Pacific Biosciences of California, In.c | Methods, systems, and reagents for direct RNA sequencing |
JP7237586B2 (ja) | 2015-12-08 | 2023-03-13 | カトリック ユニヴェルシテット ルーヴェン カーユー ルーヴェン リサーチ アンド ディベロップメント | 修飾ナノポア、それを含む組成物およびその使用 |
EP4019542A1 (en) | 2016-03-02 | 2022-06-29 | Oxford Nanopore Technologies plc | Mutant pores |
US11104709B2 (en) | 2016-04-06 | 2021-08-31 | Oxford Nanopore Technologies Ltd. | Mutant pore |
GB201609220D0 (en) | 2016-05-25 | 2016-07-06 | Oxford Nanopore Tech Ltd | Method |
EP3464616B1 (en) | 2016-05-25 | 2022-05-04 | Oxford Nanopore Technologies plc | Method |
GB201609221D0 (en) | 2016-05-25 | 2016-07-06 | Oxford Nanopore Tech Ltd | Method |
GB201611770D0 (en) | 2016-07-06 | 2016-08-17 | Oxford Nanopore Tech | Microfluidic device |
GB201616590D0 (en) | 2016-09-29 | 2016-11-16 | Oxford Nanopore Technologies Limited | Method |
GB201620450D0 (en) | 2016-12-01 | 2017-01-18 | Oxford Nanopore Tech Ltd | Method |
GB201707140D0 (en) | 2017-05-04 | 2017-06-21 | Oxford Nanopore Tech Ltd | Method |
GB201707122D0 (en) | 2017-05-04 | 2017-06-21 | Oxford Nanopore Tech Ltd | Pore |
CN110914290A (zh) | 2017-06-30 | 2020-03-24 | 弗拉芒区生物技术研究所 | 新颖蛋白孔 |
GB2569977A (en) | 2018-01-05 | 2019-07-10 | Oxford Nanopore Tech Ltd | Method |
GB201807793D0 (en) | 2018-05-14 | 2018-06-27 | Oxford Nanopore Tech Ltd | Method |
GB201808556D0 (en) | 2018-05-24 | 2018-07-11 | Oxford Nanopore Tech Ltd | Method |
GB201808554D0 (en) | 2018-05-24 | 2018-07-11 | Oxford Nanopore Tech Ltd | Method |
GB201809323D0 (en) | 2018-06-06 | 2018-07-25 | Oxford Nanopore Tech Ltd | Method |
US20220162692A1 (en) | 2018-07-30 | 2022-05-26 | Oxford University Innovation Limited | Assemblies |
WO2020043653A2 (en) | 2018-08-28 | 2020-03-05 | F. Hoffmann-La Roche Ag | Ruthenium-containing electrodes |
JP7153140B2 (ja) | 2018-12-19 | 2022-10-13 | エフ.ホフマン-ラ ロシュ アーゲー | 3’保護ヌクレオチド |
GB201821155D0 (en) | 2018-12-21 | 2019-02-06 | Oxford Nanopore Tech Ltd | Method |
WO2020183172A1 (en) | 2019-03-12 | 2020-09-17 | Oxford Nanopore Technologies Inc. | Nanopore sensing device and methods of operation and of forming it |
CN117337333A (zh) | 2021-05-19 | 2024-01-02 | 牛津纳米孔科技公开有限公司 | 用于补体链测序的方法 |
GB202112235D0 (en) | 2021-08-26 | 2021-10-13 | Oxford Nanopore Tech Ltd | Nanopore |
GB202205617D0 (en) | 2022-04-14 | 2022-06-01 | Oxford Nanopore Tech Plc | Novel modified protein pores and enzymes |
US20240026427A1 (en) | 2022-05-06 | 2024-01-25 | 10X Genomics, Inc. | Methods and compositions for in situ analysis of v(d)j sequences |
WO2024033443A1 (en) | 2022-08-09 | 2024-02-15 | Oxford Nanopore Technologies Plc | Novel pore monomers and pores |
GB202211602D0 (en) | 2022-08-09 | 2022-09-21 | Oxford Nanopore Tech Plc | Novel pore monomers and pores |
GB202211607D0 (en) | 2022-08-09 | 2022-09-21 | Oxford Nanopore Tech Plc | Novel pore monomers and pores |
WO2024089270A2 (en) | 2022-10-28 | 2024-05-02 | Oxford Nanopore Technologies Plc | Pore monomers and pores |
GB202216905D0 (en) | 2022-11-11 | 2022-12-28 | Oxford Nanopore Tech Plc | Novel pore monomers and pores |
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SG10201604316WA (en) | 2011-05-27 | 2016-07-28 | Oxford Nanopore Tech Ltd | Coupling method |
AU2012288629B2 (en) | 2011-07-25 | 2017-02-02 | Oxford Nanopore Technologies Limited | Hairpin loop method for double strand polynucleotide sequencing using transmembrane pores |
CA3113287C (en) | 2011-09-23 | 2022-12-20 | Oxford Nanopore Technologies Limited | Analysis of a polymer comprising polymer units |
US9758823B2 (en) | 2011-10-21 | 2017-09-12 | Oxford Nanopore Technologies Limited | Enzyme method |
US10385382B2 (en) | 2011-12-29 | 2019-08-20 | Oxford Nanopore Technologies Ltd. | Enzyme method |
EP2798083B1 (en) | 2011-12-29 | 2017-08-09 | Oxford Nanopore Technologies Limited | Method for characterising a polynucelotide by using a xpd helicase |
WO2013153359A1 (en) | 2012-04-10 | 2013-10-17 | Oxford Nanopore Technologies Limited | Mutant lysenin pores |
EP2875154B1 (en) | 2012-07-19 | 2017-08-23 | Oxford Nanopore Technologies Limited | SSB method for characterising a nucleic acid |
EP2875128B8 (en) | 2012-07-19 | 2020-06-24 | Oxford Nanopore Technologies Limited | Modified helicases |
EP2875152B1 (en) | 2012-07-19 | 2019-10-09 | Oxford Nanopore Technologies Limited | Enzyme construct |
MX2015012396A (es) | 2013-03-14 | 2016-02-03 | Arkema Inc | Metodos para la reticulacion de composiciones polimeras en presencia de oxigeno atmosferico. |
GB201406151D0 (en) | 2014-04-04 | 2014-05-21 | Oxford Nanopore Tech Ltd | Method |
CN117947149A (zh) | 2013-10-18 | 2024-04-30 | 牛津纳米孔科技公开有限公司 | 经修饰的酶 |
US9925679B2 (en) | 2014-05-19 | 2018-03-27 | I+D+M Creative, Llc | Devices and methods for assisting with slicing items |
-
2013
- 2013-07-18 EP EP13740351.5A patent/EP2875152B1/en active Active
- 2013-07-18 JP JP2015522172A patent/JP6429773B2/ja active Active
- 2013-07-18 AU AU2013291765A patent/AU2013291765C1/en active Active
- 2013-07-18 CA CA2879355A patent/CA2879355C/en active Active
- 2013-07-18 BR BR112015001052A patent/BR112015001052B8/pt active IP Right Grant
- 2013-07-18 US US14/415,533 patent/US9797009B2/en active Active
- 2013-07-18 WO PCT/GB2013/051928 patent/WO2014013262A1/en active Application Filing
-
2017
- 2017-09-14 US US15/704,395 patent/US20180230526A1/en not_active Abandoned
-
2018
- 2018-08-03 JP JP2018146743A patent/JP2018186830A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
JP2018186830A (ja) | 2018-11-29 |
US20150218629A1 (en) | 2015-08-06 |
WO2014013262A1 (en) | 2014-01-23 |
CA2879355A1 (en) | 2014-01-23 |
BR112015001052B8 (pt) | 2022-12-27 |
EP2875152B1 (en) | 2019-10-09 |
US20180230526A1 (en) | 2018-08-16 |
EP2875152A1 (en) | 2015-05-27 |
US9797009B2 (en) | 2017-10-24 |
JP6429773B2 (ja) | 2018-11-28 |
AU2013291765A1 (en) | 2015-02-05 |
AU2013291765B2 (en) | 2019-05-16 |
AU2013291765C1 (en) | 2019-08-08 |
JP2015529451A (ja) | 2015-10-08 |
CA2879355C (en) | 2021-09-21 |
BR112015001052B1 (pt) | 2022-04-05 |
Similar Documents
Legal Events
Date | Code | Title | Description |
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B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
B06I | Publication of requirement cancelled [chapter 6.9 patent gazette] |
Free format text: ANULADA A PUBLICACAO CODIGO 6.6.1 NA RPI NO 2462 DE 13/03/2018 POR TER SIDO INDEVIDA. |
|
B350 | Update of information on the portal [chapter 15.35 patent gazette] | ||
B350 | Update of information on the portal [chapter 15.35 patent gazette] | ||
B06A | Patent application procedure suspended [chapter 6.1 patent gazette] | ||
B09A | Decision: intention to grant [chapter 9.1 patent gazette] | ||
B16A | Patent or certificate of addition of invention granted [chapter 16.1 patent gazette] |
Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 18/07/2013, OBSERVADAS AS CONDICOES LEGAIS. |
|
B25D | Requested change of name of applicant approved |
Owner name: OXFORD NANOPORE TECHNOLOGIES PLC (GB) |
|
B25G | Requested change of headquarter approved |
Owner name: OXFORD NANOPORE TECHNOLOGIES PLC (GB) |