BR112014030813A2 - tratamento de efeitos colaterais de desordens motoras e de movimento associadas com tratamentos de doenças parkinson - Google Patents

tratamento de efeitos colaterais de desordens motoras e de movimento associadas com tratamentos de doenças parkinson

Info

Publication number
BR112014030813A2
BR112014030813A2 BR112014030813-6A BR112014030813A BR112014030813A2 BR 112014030813 A2 BR112014030813 A2 BR 112014030813A2 BR 112014030813 A BR112014030813 A BR 112014030813A BR 112014030813 A2 BR112014030813 A2 BR 112014030813A2
Authority
BR
Brazil
Prior art keywords
parkinson
side effects
motor
treatment
disease treatments
Prior art date
Application number
BR112014030813-6A
Other languages
English (en)
Inventor
Leahy Emer
Shankar Bavani
Original Assignee
Psychogenics, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Psychogenics, Inc. filed Critical Psychogenics, Inc.
Publication of BR112014030813A2 publication Critical patent/BR112014030813A2/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

resumo patente de invenção: "tratamento de efeitos colaterais de desordens motoras e de movimento associadas com tratamentos de doenças parkinson". a presente invenção refere-se aos métodos de tratamento de efeitos colaterais de desordem motora associados com a administração de levodopa em um indivíduo com a doença de parkinson, por administração de uma dose de eltoprazina ou um sal de adição de ácido farmaceuticamente aceitável. em particular, a invenção proporciona métodos para a redução da discinesia associada com tratamentos da doença de parkinson, e doses eficazes de eltoprazina ou um sal de adição de ácido farmaceuticamente aceitável.
BR112014030813-6A 2012-06-11 2013-06-06 tratamento de efeitos colaterais de desordens motoras e de movimento associadas com tratamentos de doenças parkinson BR112014030813A2 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261658401P 2012-06-11 2012-06-11
US61/658,401 2012-06-11
PCT/US2013/044509 WO2013188210A2 (en) 2012-06-11 2013-06-06 Treatment of motor and movement disorder side effects associated with parkinson's disease treatments

Publications (1)

Publication Number Publication Date
BR112014030813A2 true BR112014030813A2 (pt) 2018-05-15

Family

ID=49715794

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112014030813-6A BR112014030813A2 (pt) 2012-06-11 2013-06-06 tratamento de efeitos colaterais de desordens motoras e de movimento associadas com tratamentos de doenças parkinson

Country Status (16)

Country Link
US (2) US20130331399A1 (pt)
EP (1) EP2858649B1 (pt)
JP (3) JP2015523989A (pt)
KR (1) KR20150017763A (pt)
CN (1) CN105407879A (pt)
AU (1) AU2013274667B2 (pt)
BR (1) BR112014030813A2 (pt)
CA (1) CA2876203A1 (pt)
ES (1) ES2765200T3 (pt)
HK (1) HK1209341A1 (pt)
IL (1) IL236107A0 (pt)
MX (1) MX2014015266A (pt)
NZ (1) NZ702730A (pt)
RU (1) RU2014150942A (pt)
SG (1) SG11201408240TA (pt)
WO (1) WO2013188210A2 (pt)

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ES2421237T7 (es) 2007-08-15 2013-09-30 Arena Pharmaceuticals, Inc. Derivados de imidazo[1,2-a]piridin como moduladores del receptor serotoninérgico 5ht2a en el tratamiento de trastornos relacionados con el mismo
US20110021538A1 (en) 2008-04-02 2011-01-27 Arena Pharmaceuticals, Inc. Processes for the preparation of pyrazole derivatives useful as modulators of the 5-ht2a serotonin receptor
US9126946B2 (en) 2008-10-28 2015-09-08 Arena Pharmaceuticals, Inc. Processes useful for the preparation of 1-[3-(4-bromo-2-methyl-2H-pyrazol-3-yl)-4-methoxy-phenyl]-3-(2,4-difluoro-phenyl)urea and crystalline forms related thereto
PT2364142T (pt) 2008-10-28 2018-04-23 Arena Pharm Inc Composições de um modulador do recetor da serotonina 5-ht2a para o tratamento de distúrbios com ele relacionados
US11426366B2 (en) 2015-05-15 2022-08-30 Arizona Board Of Regents On Behalf Of The Universsity Of Arizona Compositions and methods for treating motor disorders
RU2017145976A (ru) 2015-06-12 2019-07-15 Аксовант Сайенсиз Гмбх Производные диарил- и арилгетероарилмочевины, применимые для профилактики и лечения нарушения поведения во время REM-фазы сна
KR20180064373A (ko) 2015-07-15 2018-06-14 엑소반트 사이언시즈 게엠베하 신경퇴행성 질환과 관련된 환각의 예방 및 치료에 유용한 5-ht2a 세로토닌 수용체의 조절자로서의 다이아릴 및 아릴헤테로아릴 우레아 유도체
KR101749675B1 (ko) * 2015-07-20 2017-06-26 동국대학교 산학협력단 멜라닌 응집 호르몬을 유효성분으로 포함하는 파킨슨병 치료 및 레보도파 부작용 억제용 약학 조성물
US20190054051A1 (en) * 2017-08-21 2019-02-21 The Board Of Trustees Of The Leland Stanford Junior University DOPA Formulations for Treatments of Parkinson's Disease
WO2020110128A1 (en) * 2018-11-29 2020-06-04 Prilenia Neurotherapeutics Ltd. Combination of pridopidine and an additional therapeutic agent for treating drug induced dyskinesia
US12036213B2 (en) 2017-09-08 2024-07-16 Prilenia Neurotherapeutics Ltd. Pridopidine for treating drug induced dyskinesias
CN112955134A (zh) 2018-07-19 2021-06-11 英倍尔药业股份有限公司 用于治疗帕金森氏病的左旋多巴和多巴脱羧酶抑制剂的呼吸道递送

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19938823A1 (de) * 1999-08-19 2001-02-22 Boehringer Ingelheim Pharma Medikamentöse Behandlung des Restless Leg Syndroms
US7706871B2 (en) * 2003-05-06 2010-04-27 Nellcor Puritan Bennett Llc System and method of prediction of response to neurological treatment using the electroencephalogram
KR101746756B1 (ko) * 2008-05-30 2017-06-27 싸이코제닉스 아이엔씨. 신경계 질환 및 정신 질환의 치료
WO2009156380A1 (en) * 2008-06-24 2009-12-30 Bjoerklund Anders Eltoprazine for suppression of l-dopa induced dyskinesias
DE102008030539B4 (de) * 2008-06-27 2016-05-12 BSH Bosch und Siemens Hausgeräte GmbH Haushaltsgerät
EP3586923B1 (en) * 2008-07-14 2021-06-16 Arizona Board Of Regents For And On Behalf Of Arizona State University Devices for modulating cellular activity using ultrasound
TW201029995A (en) * 2008-12-05 2010-08-16 Merz Pharma Gmbh & Co Kgaa Use of eltoprazine for the treatment of L-DOPA-induced dyskinesia
WO2012048710A1 (en) * 2010-10-15 2012-04-19 Concit Pharma Aps Combinations of serotonin receptor agonists for treatment of movement disorders

Also Published As

Publication number Publication date
RU2014150942A (ru) 2016-07-27
EP2858649A2 (en) 2015-04-15
NZ702730A (en) 2017-08-25
EP2858649A4 (en) 2016-05-25
US20180250295A1 (en) 2018-09-06
JP2015523989A (ja) 2015-08-20
MX2014015266A (es) 2015-06-23
IL236107A0 (en) 2015-01-29
CN105407879A (zh) 2016-03-16
JP2018083842A (ja) 2018-05-31
JP2020073549A (ja) 2020-05-14
KR20150017763A (ko) 2015-02-17
SG11201408240TA (en) 2015-01-29
AU2013274667B2 (en) 2018-03-08
HK1209341A1 (en) 2016-04-01
CA2876203A1 (en) 2013-12-19
US20130331399A1 (en) 2013-12-12
WO2013188210A2 (en) 2013-12-19
WO2013188210A3 (en) 2015-07-02
EP2858649B1 (en) 2019-10-23
ES2765200T3 (es) 2020-06-08
AU2013274667A1 (en) 2015-01-22

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Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]

Free format text: DE ACORDO COM O ARTIGO 229-C DA LEI NO 10196/2001, QUE MODIFICOU A LEI NO 9279/96, A CONCESSAO DA PATENTE ESTA CONDICIONADA A ANUENCIA PREVIA DA ANVISA. CONSIDERANDO A APROVACAO DOS TERMOS DO PARECER NO 337/PGF/EA/2010, BEM COMO A PORTARIA INTERMINISTERIAL NO 1065 DE 24/05/2012, ENCAMINHA-SE O PRESENTE PEDIDO PARA AS PROVIDENCIAS CABIVEIS.

B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]
B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B11B Dismissal acc. art. 36, par 1 of ipl - no reply within 90 days to fullfil the necessary requirements