BR112014030813A2 - tratamento de efeitos colaterais de desordens motoras e de movimento associadas com tratamentos de doenças parkinson - Google Patents
tratamento de efeitos colaterais de desordens motoras e de movimento associadas com tratamentos de doenças parkinsonInfo
- Publication number
- BR112014030813A2 BR112014030813A2 BR112014030813-6A BR112014030813A BR112014030813A2 BR 112014030813 A2 BR112014030813 A2 BR 112014030813A2 BR 112014030813 A BR112014030813 A BR 112014030813A BR 112014030813 A2 BR112014030813 A2 BR 112014030813A2
- Authority
- BR
- Brazil
- Prior art keywords
- parkinson
- side effects
- motor
- treatment
- disease treatments
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid, pantothenic acid
- A61K31/198—Alpha-aminoacids, e.g. alanine, edetic acids [EDTA]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
resumo patente de invenção: "tratamento de efeitos colaterais de desordens motoras e de movimento associadas com tratamentos de doenças parkinson". a presente invenção refere-se aos métodos de tratamento de efeitos colaterais de desordem motora associados com a administração de levodopa em um indivíduo com a doença de parkinson, por administração de uma dose de eltoprazina ou um sal de adição de ácido farmaceuticamente aceitável. em particular, a invenção proporciona métodos para a redução da discinesia associada com tratamentos da doença de parkinson, e doses eficazes de eltoprazina ou um sal de adição de ácido farmaceuticamente aceitável.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201261658401P | 2012-06-11 | 2012-06-11 | |
US61/658,401 | 2012-06-11 | ||
PCT/US2013/044509 WO2013188210A2 (en) | 2012-06-11 | 2013-06-06 | Treatment of motor and movement disorder side effects associated with parkinson's disease treatments |
Publications (1)
Publication Number | Publication Date |
---|---|
BR112014030813A2 true BR112014030813A2 (pt) | 2018-05-15 |
Family
ID=49715794
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112014030813-6A BR112014030813A2 (pt) | 2012-06-11 | 2013-06-06 | tratamento de efeitos colaterais de desordens motoras e de movimento associadas com tratamentos de doenças parkinson |
Country Status (16)
Country | Link |
---|---|
US (2) | US20130331399A1 (pt) |
EP (1) | EP2858649B1 (pt) |
JP (3) | JP2015523989A (pt) |
KR (1) | KR20150017763A (pt) |
CN (1) | CN105407879A (pt) |
AU (1) | AU2013274667B2 (pt) |
BR (1) | BR112014030813A2 (pt) |
CA (1) | CA2876203A1 (pt) |
ES (1) | ES2765200T3 (pt) |
HK (1) | HK1209341A1 (pt) |
IL (1) | IL236107A0 (pt) |
MX (1) | MX2014015266A (pt) |
NZ (1) | NZ702730A (pt) |
RU (1) | RU2014150942A (pt) |
SG (1) | SG11201408240TA (pt) |
WO (1) | WO2013188210A2 (pt) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2009023253A2 (en) | 2007-08-15 | 2009-02-19 | Arena Pharmaceuticals Inc. | IMIDAZO[L,2-α]PYRIDINE DERIVATIVES AS MODULATORS OF THE 5-HT2A SEROTONIN RECEPTOR USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO |
US20110021538A1 (en) | 2008-04-02 | 2011-01-27 | Arena Pharmaceuticals, Inc. | Processes for the preparation of pyrazole derivatives useful as modulators of the 5-ht2a serotonin receptor |
ES2666324T3 (es) | 2008-10-28 | 2018-05-04 | Arena Pharmaceuticals, Inc. | Composiciones de un modulador del receptor de serotonina 5-HT2A útiles para el tratamiento de trastornos relacionados con el mismo |
WO2010062321A1 (en) | 2008-10-28 | 2010-06-03 | Arena Pharmaceuticals, Inc. | Processes useful for the preparation of 1-[3-(4-bromo-2-methyl-2h-pyrazol-3-yl)-4-methoxy-phenyl]-3-(2,4-difluoro-phenyl)-urea and crystalline forms related thereto |
WO2016186968A1 (en) | 2015-05-15 | 2016-11-24 | The Arizona Board Of Regents On Behalf Of The University Of Arizona | Compositions and methods for treating motor disorders |
JP2018516992A (ja) | 2015-06-12 | 2018-06-28 | アクソファント サイエンシーズ ゲーエムベーハーAxovant Sciences Gmbh | レム睡眠行動障害の予防および処置のために有用なジアリールおよびアリールヘテロアリール尿素誘導体 |
RU2018103338A (ru) * | 2015-07-15 | 2019-08-15 | Аксовант Сайенсиз Гмбх | Производные диарил- и арилгетероарилмочевины для профилактики и лечения галлюцинаций, ассоциированных с нейродегенеративным заболеванием |
KR101749675B1 (ko) * | 2015-07-20 | 2017-06-26 | 동국대학교 산학협력단 | 멜라닌 응집 호르몬을 유효성분으로 포함하는 파킨슨병 치료 및 레보도파 부작용 억제용 약학 조성물 |
US20190054051A1 (en) * | 2017-08-21 | 2019-02-21 | The Board Of Trustees Of The Leland Stanford Junior University | DOPA Formulations for Treatments of Parkinson's Disease |
WO2020110128A1 (en) * | 2018-11-29 | 2020-06-04 | Prilenia Neurotherapeutics Ltd. | Combination of pridopidine and an additional therapeutic agent for treating drug induced dyskinesia |
US11517548B2 (en) | 2018-07-19 | 2022-12-06 | Impel Pharmaceuticals Inc. | Respiratory tract delivery of levodopa and DOPA decarboxylase inhibitor for treatment of Parkinson's Disease |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE19938823A1 (de) * | 1999-08-19 | 2001-02-22 | Boehringer Ingelheim Pharma | Medikamentöse Behandlung des Restless Leg Syndroms |
US7706871B2 (en) * | 2003-05-06 | 2010-04-27 | Nellcor Puritan Bennett Llc | System and method of prediction of response to neurological treatment using the electroencephalogram |
EP2374459A1 (en) * | 2008-05-30 | 2011-10-12 | Psychogenics Inc. | Treatment for neurological and mental disorders |
US20110183995A1 (en) * | 2008-06-24 | 2011-07-28 | Neurosearch A/S | Eltoprazine for suppression of l-dopa induced dyskinesias |
DE102008030539B4 (de) * | 2008-06-27 | 2016-05-12 | BSH Bosch und Siemens Hausgeräte GmbH | Haushaltsgerät |
EP3586923B1 (en) * | 2008-07-14 | 2021-06-16 | Arizona Board Of Regents For And On Behalf Of Arizona State University | Devices for modulating cellular activity using ultrasound |
TW201029995A (en) * | 2008-12-05 | 2010-08-16 | Merz Pharma Gmbh & Co Kgaa | Use of eltoprazine for the treatment of L-DOPA-induced dyskinesia |
RU2611376C2 (ru) * | 2010-10-15 | 2017-02-21 | Контера Фарма Апс | Фармацевтическая композиция для лечения, профилактики или облегчения двигательных расстройств и ее применение |
-
2013
- 2013-06-06 US US13/911,639 patent/US20130331399A1/en not_active Abandoned
- 2013-06-06 SG SG11201408240TA patent/SG11201408240TA/en unknown
- 2013-06-06 WO PCT/US2013/044509 patent/WO2013188210A2/en active Application Filing
- 2013-06-06 BR BR112014030813-6A patent/BR112014030813A2/pt not_active Application Discontinuation
- 2013-06-06 AU AU2013274667A patent/AU2013274667B2/en not_active Ceased
- 2013-06-06 EP EP13805005.9A patent/EP2858649B1/en active Active
- 2013-06-06 CN CN201380038276.2A patent/CN105407879A/zh active Pending
- 2013-06-06 ES ES13805005T patent/ES2765200T3/es active Active
- 2013-06-06 MX MX2014015266A patent/MX2014015266A/es unknown
- 2013-06-06 RU RU2014150942A patent/RU2014150942A/ru not_active Application Discontinuation
- 2013-06-06 KR KR1020157000394A patent/KR20150017763A/ko not_active Application Discontinuation
- 2013-06-06 CA CA2876203A patent/CA2876203A1/en not_active Abandoned
- 2013-06-06 NZ NZ702730A patent/NZ702730A/en not_active IP Right Cessation
- 2013-06-06 JP JP2015516210A patent/JP2015523989A/ja active Pending
-
2014
- 2014-12-07 IL IL236107A patent/IL236107A0/en unknown
-
2015
- 2015-10-15 HK HK15110110.7A patent/HK1209341A1/xx unknown
-
2018
- 2018-01-26 JP JP2018011271A patent/JP2018083842A/ja active Pending
- 2018-05-04 US US15/971,222 patent/US20180250295A1/en not_active Abandoned
-
2019
- 2019-12-27 JP JP2019238531A patent/JP2020073549A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
WO2013188210A2 (en) | 2013-12-19 |
EP2858649A4 (en) | 2016-05-25 |
IL236107A0 (en) | 2015-01-29 |
RU2014150942A (ru) | 2016-07-27 |
CA2876203A1 (en) | 2013-12-19 |
US20130331399A1 (en) | 2013-12-12 |
CN105407879A (zh) | 2016-03-16 |
ES2765200T3 (es) | 2020-06-08 |
US20180250295A1 (en) | 2018-09-06 |
KR20150017763A (ko) | 2015-02-17 |
JP2018083842A (ja) | 2018-05-31 |
EP2858649B1 (en) | 2019-10-23 |
SG11201408240TA (en) | 2015-01-29 |
WO2013188210A3 (en) | 2015-07-02 |
JP2020073549A (ja) | 2020-05-14 |
NZ702730A (en) | 2017-08-25 |
AU2013274667A1 (en) | 2015-01-22 |
AU2013274667B2 (en) | 2018-03-08 |
HK1209341A1 (en) | 2016-04-01 |
JP2015523989A (ja) | 2015-08-20 |
EP2858649A2 (en) | 2015-04-15 |
MX2014015266A (es) | 2015-06-23 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] |
Free format text: DE ACORDO COM O ARTIGO 229-C DA LEI NO 10196/2001, QUE MODIFICOU A LEI NO 9279/96, A CONCESSAO DA PATENTE ESTA CONDICIONADA A ANUENCIA PREVIA DA ANVISA. CONSIDERANDO A APROVACAO DOS TERMOS DO PARECER NO 337/PGF/EA/2010, BEM COMO A PORTARIA INTERMINISTERIAL NO 1065 DE 24/05/2012, ENCAMINHA-SE O PRESENTE PEDIDO PARA AS PROVIDENCIAS CABIVEIS. |
|
B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] | ||
B06U | Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette] | ||
B11B | Dismissal acc. art. 36, par 1 of ipl - no reply within 90 days to fullfil the necessary requirements |