BR112014029642A2 - composto, combinação de um composto, composição farmacêutica, uso de um composto, dispositivo e kit - Google Patents
composto, combinação de um composto, composição farmacêutica, uso de um composto, dispositivo e kitInfo
- Publication number
- BR112014029642A2 BR112014029642A2 BR112014029642A BR112014029642A BR112014029642A2 BR 112014029642 A2 BR112014029642 A2 BR 112014029642A2 BR 112014029642 A BR112014029642 A BR 112014029642A BR 112014029642 A BR112014029642 A BR 112014029642A BR 112014029642 A2 BR112014029642 A2 BR 112014029642A2
- Authority
- BR
- Brazil
- Prior art keywords
- compound
- kit
- combination
- pharmaceutical composition
- pharmaceutical
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
- A61K31/381—Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4436—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a heterocyclic ring having sulfur as a ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Pulmonology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP12170714 | 2012-06-04 | ||
| PCT/EP2013/060915 WO2013182451A1 (en) | 2012-06-04 | 2013-05-28 | Derivatives of 1-phenyl-2-pyridinyl alkyl alcohols as phosphodiesterase inhibitors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR112014029642A2 true BR112014029642A2 (pt) | 2017-06-27 |
Family
ID=48670496
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112014029642A BR112014029642A2 (pt) | 2012-06-04 | 2013-05-28 | composto, combinação de um composto, composição farmacêutica, uso de um composto, dispositivo e kit |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US9440954B2 (cg-RX-API-DMAC10.html) |
| EP (1) | EP2855450B1 (cg-RX-API-DMAC10.html) |
| KR (1) | KR20150022789A (cg-RX-API-DMAC10.html) |
| CN (1) | CN104334542A (cg-RX-API-DMAC10.html) |
| AR (1) | AR091261A1 (cg-RX-API-DMAC10.html) |
| BR (1) | BR112014029642A2 (cg-RX-API-DMAC10.html) |
| CA (1) | CA2875421A1 (cg-RX-API-DMAC10.html) |
| HK (1) | HK1205116A1 (cg-RX-API-DMAC10.html) |
| IN (1) | IN2014DN10239A (cg-RX-API-DMAC10.html) |
| RU (1) | RU2637945C2 (cg-RX-API-DMAC10.html) |
| WO (1) | WO2013182451A1 (cg-RX-API-DMAC10.html) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2022783A1 (en) | 2007-08-08 | 2009-02-11 | CHIESI FARMACEUTICI S.p.A. | "Derivatives of 1-phenyl-2-pyridinyl alkyl alcohols as phosphodiesterase inhibitors" |
| EP2216327A1 (en) | 2009-02-06 | 2010-08-11 | CHIESI FARMACEUTICI S.p.A. | Benzoic acid (1-phenyl-2-pyridin-4-yl)ethyl esters as phosphodiesterase inhibitors |
| PH12013502516A1 (en) | 2011-06-06 | 2017-08-23 | Chiesi Farm Spa | Derivatives of 1-phenyl-2-pyridinyl alkyl alcohols as phosphodiesterase inhibitors |
| CN103827088B (zh) | 2011-09-26 | 2017-10-13 | 奇斯药制品公司 | 作为磷酸二酯酶抑制剂的1‑苯基‑2‑吡啶基烷基醇的衍生物 |
| CA2893628C (en) | 2012-12-05 | 2021-11-30 | Chiesi Farmaceutici S.P.A. | 1-phenyl-2-pyridinyl alkyl alcohol derivatives as phosphodiesterase inhibitors |
| CA2893622A1 (en) | 2012-12-05 | 2014-06-12 | Chiesi Farmaceutici S.P.A. | Novel compounds |
| TR201807181T4 (tr) | 2012-12-05 | 2018-06-21 | Chiesi Farm Spa | Pde-4 i̇nhi̇bi̇törleri̇ ve muskari̇ni̇k reseptör antagoni̇stleri̇ olarak feni̇leti̇lpi̇ri̇di̇n türevleri̇ |
| CN104837828B (zh) | 2012-12-05 | 2017-07-18 | 奇斯药制品公司 | 作为pde4‑抑制剂的苯基乙基吡啶衍生物 |
| AR104822A1 (es) * | 2015-06-01 | 2017-08-16 | Chiesi Farm Spa | Derivado de aminoésteres |
| TW201710254A (zh) * | 2015-06-01 | 2017-03-16 | 吉斯藥品公司 | 胺基酯衍生物 |
| JP7575952B2 (ja) | 2019-01-08 | 2024-10-30 | 杏林製薬株式会社 | １５－ｐｇｄｈ阻害薬 |
| WO2020160151A1 (en) | 2019-01-31 | 2020-08-06 | Kyorin Pharmaceutical Co., Ltd. | 15-pgdh inhibitors |
| CN116082670B (zh) * | 2023-04-11 | 2023-06-27 | 中国人民解放军军事科学院军事医学研究院 | 一种含有季膦盐的声响应假性共轭聚合物纳米颗粒的制备方法及其在抗菌领域的应用 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL106517A0 (en) | 1992-07-28 | 1994-08-26 | Rhone Poulenc Rorer Ltd | Compounds containing phenyl linked to aryl or heteroaryl by an aliphatic or heteroatom containing linking group |
| US5786354A (en) | 1994-06-21 | 1998-07-28 | Celltech Therapeutics, Limited | Tri-substituted phenyl derivatives and processes for their preparation |
| WO2004096274A1 (ja) | 2003-03-31 | 2004-11-11 | Kyowa Hakko Kogyo Co., Ltd. | 気道内投与剤 |
| DE602007012105D1 (de) * | 2006-07-14 | 2011-03-03 | Chiesi Farma Spa | Derivate von 1-phenyl-2-pyridinylalkylenalkohole als phosphodiesteraseinhibitoren |
| PL2114951T3 (pl) * | 2007-02-28 | 2014-10-31 | Leo Pharma As | Nowe inhibitory fosfodiesterazy |
| EP2022783A1 (en) | 2007-08-08 | 2009-02-11 | CHIESI FARMACEUTICI S.p.A. | "Derivatives of 1-phenyl-2-pyridinyl alkyl alcohols as phosphodiesterase inhibitors" |
| EP2070913A1 (en) | 2007-12-14 | 2009-06-17 | CHIESI FARMACEUTICI S.p.A. | Ester derivatives as phosphodiesterase inhibitors |
| EP2110375A1 (en) | 2008-04-14 | 2009-10-21 | CHIESI FARMACEUTICI S.p.A. | Phosphodiesterase-4 inhibitors belonging to the tertiary amine class |
| EP2216327A1 (en) | 2009-02-06 | 2010-08-11 | CHIESI FARMACEUTICI S.p.A. | Benzoic acid (1-phenyl-2-pyridin-4-yl)ethyl esters as phosphodiesterase inhibitors |
| PH12013502516A1 (en) | 2011-06-06 | 2017-08-23 | Chiesi Farm Spa | Derivatives of 1-phenyl-2-pyridinyl alkyl alcohols as phosphodiesterase inhibitors |
| CN103827088B (zh) | 2011-09-26 | 2017-10-13 | 奇斯药制品公司 | 作为磷酸二酯酶抑制剂的1‑苯基‑2‑吡啶基烷基醇的衍生物 |
| KR20140078719A (ko) | 2011-10-21 | 2014-06-25 | 키에시 파르마슈티시 엣스. 피. 에이. | 포스포디에스테라제 억제제로서 1-페닐-2-피리디닐 알킬 알코올의 유도체 |
-
2013
- 2013-05-28 KR KR20147033409A patent/KR20150022789A/ko not_active Withdrawn
- 2013-05-28 WO PCT/EP2013/060915 patent/WO2013182451A1/en not_active Ceased
- 2013-05-28 BR BR112014029642A patent/BR112014029642A2/pt not_active IP Right Cessation
- 2013-05-28 IN IN10239DEN2014 patent/IN2014DN10239A/en unknown
- 2013-05-28 HK HK15105703.0A patent/HK1205116A1/xx unknown
- 2013-05-28 RU RU2014148316A patent/RU2637945C2/ru active
- 2013-05-28 CN CN201380029435.2A patent/CN104334542A/zh active Pending
- 2013-05-28 CA CA2875421A patent/CA2875421A1/en not_active Abandoned
- 2013-05-28 EP EP13730498.6A patent/EP2855450B1/en active Active
- 2013-06-03 AR ARP130101959 patent/AR091261A1/es unknown
- 2013-06-04 US US13/909,222 patent/US9440954B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| WO2013182451A1 (en) | 2013-12-12 |
| RU2014148316A (ru) | 2016-07-27 |
| WO2013182451A9 (en) | 2014-02-06 |
| KR20150022789A (ko) | 2015-03-04 |
| EP2855450A1 (en) | 2015-04-08 |
| US20130324501A1 (en) | 2013-12-05 |
| IN2014DN10239A (cg-RX-API-DMAC10.html) | 2015-08-07 |
| CA2875421A1 (en) | 2013-12-12 |
| EP2855450B1 (en) | 2016-07-06 |
| US9440954B2 (en) | 2016-09-13 |
| CN104334542A (zh) | 2015-02-04 |
| AR091261A1 (es) | 2015-01-21 |
| RU2637945C2 (ru) | 2017-12-08 |
| HK1205116A1 (en) | 2015-12-11 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| BR112015000420A2 (pt) | composto, composição farmacêutica, e, uso de um composto | |
| BR112014029115A2 (pt) | composto, composição farmacêutica, e, uso de um composto ou composição | |
| BR112014029530A2 (pt) | compostos, composição farmacêutica e uso de um composto | |
| BR112014001255A2 (pt) | composto, uso de um composto, combinação, e, composição farmacêutica | |
| BR112013030302A2 (pt) | composto, composição farmacêutica, uso de um composto, combinação de um composto e dispositivo | |
| BR112014013760A2 (pt) | composto, composição farmacêutica e uso de um composto | |
| BR112013008259A2 (pt) | composto, composição farmacêutica, e, uso de um composto | |
| BR112013015397A2 (pt) | composto, composição farmacêutica, e, uso de um composto | |
| BR112014005669A2 (pt) | composto, composição farmacêutica e uso de um composto | |
| BR112014003567A2 (pt) | composto, uso de um composto, e, composição farmacêutica | |
| BR112016003229A2 (pt) | Composto, composição farmacêutica, e, uso de um composto ou de uma composição farmacêutica | |
| CR20150380A (es) | Compuestos de carbamoilpiridona policíclicos y su uso farmacéutico | |
| BR112014000260A2 (pt) | composto, e, uso de um composto | |
| BR112013011448A2 (pt) | composto, composição farnmacêutica, e, uso do composto | |
| BR112014009471A2 (pt) | compostos, combinação de um composto, composição farmacêutica, uso de um composto, dispositivo e kit | |
| BR112014014547A2 (pt) | compostos antagonistas de e-selectina, composições e métodos de uso | |
| BR112014023200A2 (pt) | uso de uma composição | |
| BR112012031226A2 (pt) | composto, uso do composto, composição farmacêutica, e uso de composição farmacêutica | |
| PT2585437E (pt) | Compostos de tioacetato, composições e métodos de uso | |
| BR112015002738A2 (pt) | composto , e , composição farmacêutica | |
| BR112013029206A2 (pt) | composto, e, uso de um composto | |
| BR112013006016A2 (pt) | compostos de azabenzotiazol, composições e métodos de uso | |
| BR112014016635A2 (pt) | composto, composição, e, uso de um composto | |
| BR112014013177A2 (pt) | composto, composição farmacêutica e uso de um composto | |
| BR112014013178A2 (pt) | composto, composição farmacêutica e uso de um composto |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B08F | Application fees: dismissal - article 86 of industrial property law |
Free format text: REFERENTE A 4A ANUIDADE. |
|
| B08K | Lapse as no evidence of payment of the annual fee has been furnished to inpi (acc. art. 87) |