BR112014016682A2 - método para a modificação de pelo menos um locus alvo em uma célula vegetal, célula vegetal ou núcleico de célula vegetal e tecido vegetal - Google Patents

método para a modificação de pelo menos um locus alvo em uma célula vegetal, célula vegetal ou núcleico de célula vegetal e tecido vegetal

Info

Publication number
BR112014016682A2
BR112014016682A2 BR112014016682A BR112014016682A BR112014016682A2 BR 112014016682 A2 BR112014016682 A2 BR 112014016682A2 BR 112014016682 A BR112014016682 A BR 112014016682A BR 112014016682 A BR112014016682 A BR 112014016682A BR 112014016682 A2 BR112014016682 A2 BR 112014016682A2
Authority
BR
Brazil
Prior art keywords
plant cell
plant
modifying
target locus
tissue
Prior art date
Application number
BR112014016682A
Other languages
English (en)
Other versions
BR112014016682A8 (pt
Inventor
Biesgen Christian
Fauser Friedrich
Puchta Holger
Pacher Michael
Roth Nadine
Sanchez-Fernandez Rocio
Original Assignee
Basf Plant Science Co Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basf Plant Science Co Gmbh filed Critical Basf Plant Science Co Gmbh
Publication of BR112014016682A2 publication Critical patent/BR112014016682A2/pt
Publication of BR112014016682A8 publication Critical patent/BR112014016682A8/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/87Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/90Stable introduction of foreign DNA into chromosome
    • C12N15/902Stable introduction of foreign DNA into chromosome using homologous recombination
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8201Methods for introducing genetic material into plant cells, e.g. DNA, RNA, stable or transient incorporation, tissue culture methods adapted for transformation
    • C12N15/8213Targeted insertion of genes into the plant genome by homologous recombination
BR112014016682A 2012-01-06 2013-01-04 método para a modificação de pelo menos um locus alvo em uma célula vegetal, célula vegetal ou núcleico de célula vegetal e tecido vegetal BR112014016682A8 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261583651P 2012-01-06 2012-01-06
EP12150383.3A EP2612918A1 (en) 2012-01-06 2012-01-06 In planta recombination
PCT/IB2013/050080 WO2013102875A1 (en) 2012-01-06 2013-01-04 In planta recombination

Publications (2)

Publication Number Publication Date
BR112014016682A2 true BR112014016682A2 (pt) 2017-06-13
BR112014016682A8 BR112014016682A8 (pt) 2017-07-04

Family

ID=45463457

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112014016682A BR112014016682A8 (pt) 2012-01-06 2013-01-04 método para a modificação de pelo menos um locus alvo em uma célula vegetal, célula vegetal ou núcleico de célula vegetal e tecido vegetal

Country Status (5)

Country Link
US (1) US10876135B2 (pt)
EP (2) EP2612918A1 (pt)
BR (1) BR112014016682A8 (pt)
CA (1) CA2857934A1 (pt)
WO (1) WO2013102875A1 (pt)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2687605A1 (en) * 2012-07-19 2014-01-22 Biogemma Method for performing homologous recombination
CA2908403A1 (en) * 2013-04-02 2014-10-09 Bayer Cropscience Nv Targeted genome engineering in eukaryotes
AU2015253536A1 (en) * 2014-04-28 2016-11-17 Dow Agrosciences Llc Haploid maize transformation
EP3472315A4 (en) * 2016-06-20 2019-11-27 Dow Agrosciences LLC METHOD AND COMPOSITIONS FOR PRODUCING TARGETED RECOMBINATION AND BREAKING CONNECTION BETWEEN CHARACTERISTICS
WO2020157164A1 (en) 2019-01-30 2020-08-06 Enobraq Modified plant with improved rubisco activity

Family Cites Families (102)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5352605A (en) 1983-01-17 1994-10-04 Monsanto Company Chimeric genes for transforming plant cells using viral promoters
JPH0714349B2 (ja) 1983-01-17 1995-02-22 モンサント カンパニ− 植物細胞での発現に適したキメラ遺伝子
US5504200A (en) 1983-04-15 1996-04-02 Mycogen Plant Science, Inc. Plant gene expression
US5420034A (en) 1986-07-31 1995-05-30 Calgene, Inc. Seed-specific transcriptional regulation
US5254799A (en) 1985-01-18 1993-10-19 Plant Genetic Systems N.V. Transformation vectors allowing expression of Bacillus thuringiensis endotoxins in plants
US4962028A (en) 1986-07-09 1990-10-09 Dna Plant Technology Corporation Plant promotors
US5004863B2 (en) 1986-12-03 2000-10-17 Agracetus Genetic engineering of cotton plants and lines
IL84459A (en) 1986-12-05 1993-07-08 Agracetus Apparatus and method for the injection of carrier particles carrying genetic material into living cells
US5614395A (en) 1988-03-08 1997-03-25 Ciba-Geigy Corporation Chemically regulatable and anti-pathogenic DNA sequences and uses thereof
NZ228320A (en) 1988-03-29 1991-06-25 Du Pont Nucleic acid promoter fragments of the promoter region homologous to the em gene of wheat, dna constructs therefrom and plants thereof
DE3843628A1 (de) 1988-12-21 1990-07-05 Inst Genbiologische Forschung Wundinduzierbare und kartoffelknollenspezifische transkriptionale regulation
EP0463056A1 (en) 1989-03-17 1992-01-02 E.I. Du Pont De Nemours And Company External regulation of gene expression
US5086169A (en) 1989-04-20 1992-02-04 The Research Foundation Of State University Of New York Isolated pollen-specific promoter of corn
WO1991001373A1 (en) 1989-07-19 1991-02-07 Calgene, Inc. Fruit-specific transcriptional factors
ATE157012T1 (de) 1989-11-03 1997-09-15 Univ Vanderbilt Verfahren zur in vivo-verabreichung von funktionsfähigen fremden genen
GB9005772D0 (en) 1990-03-14 1990-05-09 Cambridge Advanced Tech Plant promoter
DE69132725T2 (de) 1990-03-16 2002-07-11 Calgene Llc Davis Neue sequenzen vorzugsweise exprimiert während der frühen keimentwicklung und darauf bezogene methoden
US5279833A (en) 1990-04-04 1994-01-18 Yale University Liposomal transfection of nucleic acids into animal cells
US5633446A (en) 1990-04-18 1997-05-27 Plant Genetic Systems, N.V. Modified Bacillus thuringiensis insecticidal-crystal protein genes and their expression in plant cells
US5187267A (en) 1990-06-19 1993-02-16 Calgene, Inc. Plant proteins, promoters, coding sequences and use
US5679558A (en) 1992-04-15 1997-10-21 Plant Genetic Systems, N.V. Transformation of monocot cells
WO1993024640A2 (en) 1992-06-04 1993-12-09 The Regents Of The University Of California Methods and compositions for in vivo gene therapy
CA2151267A1 (en) 1992-12-16 1994-06-23 Robert Bruce Knox Developmental regulation in anther tissue of plants
WO1994029465A1 (en) 1993-06-08 1994-12-22 Nunhems Zaden B.V. Process for generating male sterile plants
GB9324707D0 (en) 1993-12-02 1994-01-19 Olsen Odd Arne Promoter
US5689052A (en) 1993-12-22 1997-11-18 Monsanto Company Synthetic DNA sequences having enhanced expression in monocotyledonous plants and method for preparation thereof
GB9403512D0 (en) 1994-02-24 1994-04-13 Olsen Odd Arne Promoter
US6013859A (en) 1994-07-14 2000-01-11 Pioneer Hi-Bred International, Inc. Molecular methods of hybrid seed production
GB9824544D0 (en) 1998-11-09 1999-01-06 Medical Res Council Screening system
GB9421286D0 (en) 1994-10-21 1994-12-07 Danisco Promoter
US5962769A (en) 1995-06-07 1999-10-05 Pioneer Hi-Bred International, Inc. Induction of male sterility in plants by expression of high levels of avidin
ATE329047T1 (de) 1995-08-30 2006-06-15 Basf Plant Science Gmbh Stimulierung der homologen rekombination in pflanzlichen organismen mittels rekombinations fördernder enzyme
AR006928A1 (es) 1996-05-01 1999-09-29 Pioneer Hi Bred Int Una molecula de adn aislada que codifica una proteina fluorescente verde como marcador rastreable para la transformacion de plantas, un metodo para laproduccion de plantas transgenicas, un vector de expresion, una planta transgenica y celulas de dichas plantas.
DE19619353A1 (de) 1996-05-14 1997-11-20 Bosch Gmbh Robert Verfahren zur Herstellung eines integriert optischen Wellenleiterbauteiles sowie Anordnung
US5977436A (en) 1997-04-09 1999-11-02 Rhone Poulenc Agrochimie Oleosin 5' regulatory region for the modification of plant seed lipid composition
EP0870836A1 (de) 1997-04-09 1998-10-14 IPK Gatersleben 2-Desoxyglucose-6-Phosphat (2-DOG-6-P) Phosphatase DNA-Sequenzen als Selektionsmarker in Pflanzen
HUP0002501A3 (en) 1997-05-30 2001-11-28 Univ Montreal Mcgill Method for enhancement of naturally occurring cytoplasmic male sterility and for restoration of male fertility and uses thereof in hybrid crop production
NZ502466A (en) 1997-07-25 2002-10-25 Univ Melbourne Nucleic acid molecules and their use in the control of male plant sterility
GB9719359D0 (en) 1997-09-11 1997-11-12 Nickerson Biocem Ltd The Use of DNA Sequences
AU746032B2 (en) 1997-09-30 2002-04-11 Regents Of The University Of California, The Production of proteins in plant seeds
ES2385307T3 (es) 1998-02-20 2012-07-20 Syngenta Limited Producción de semillas híbridas
US6596509B1 (en) 1998-07-10 2003-07-22 Cornell Research Foundation, Inc. Recombinant constructs and systems for secretion of proteins via type III secretion systems
US6180850B1 (en) 1998-09-02 2001-01-30 Pioneer Hi-Bred International, Inc. Maize Ku70 orthologue and uses thereof
DE19852195C2 (de) 1998-11-04 2000-11-02 Inst Pflanzengenetik & Kultur Neue Expressionskassette zur Expression von beliebigen Genen in Pflanzensamen
JP2002539839A (ja) 1999-03-31 2002-11-26 インヴィトロゲン・コーポレーション 転位ポリペプチドによる機能性タンパク質配列の送達
NL1015252C2 (nl) 2000-05-19 2001-11-20 Univ Leiden Werkwijze voor het teweegbrengen van een verandering in een cel, en een vector.
EP1366154A2 (en) 2000-09-15 2003-12-03 Her Majesty in right of Canada as represented by The Minister of Agricuture and Agri-Food Canada, Saskatoon Research Center Modulation of meiotic recombination
AU2002243645A1 (en) 2001-01-22 2002-07-30 Sangamo Biosciences, Inc. Zinc finger proteins for dna binding and gene regulation in plants
DE10114209A1 (de) 2001-03-23 2002-12-05 Icon Genetics Ag Ortsgerichtete Transformation durch Verwendung von Amplifikationsvektoren
AU2002312666A1 (en) 2001-06-07 2002-12-16 National Research Council Of Canada Anther-specific taa1 genes encoding fatty acyl co-a reductases, and uses thereof
US7071375B2 (en) 2001-07-12 2006-07-04 Mcgill University Nuclear fertility restorer genes and methods of use in plants
US7314971B2 (en) 2001-07-12 2008-01-01 Basf Plant Science Gmbh Nuclear fertility restorer genes and methods of use in plants
ES2537649T3 (es) 2002-02-26 2015-06-10 Syngenta Limited Método para producir selectivamente plantas estériles masculinas o femeninas
AU2003234128A1 (en) 2002-04-17 2003-11-03 Sangamo Biosciences, Inc. Compositions and methods for regulation of plant gamma-tocopherol methyltransferase
CA2496537A1 (en) 2002-08-23 2004-03-04 Basf Plant Science Gmbh Male ferility restoration as a selectable marker in plant transformation
DE60318603T2 (de) 2002-09-03 2008-07-03 Université Libre de Bruxelles Reversible, parallele und zur vielfältigen aufgabenbewältigung verwendbare (multitask) klonierungsmethode und entprechende reagentien
WO2004070035A2 (en) 2003-02-03 2004-08-19 Sungene Gmbh & Co. Kgaa Method for increasing efficiency of homologous recombination in plants
EP1689870B1 (en) 2003-11-18 2008-12-31 Bayer BioScience N.V. Improved targeted dna insertion in plants
DE102004010023A1 (de) 2004-03-02 2005-09-22 Martin-Luther-Universität Halle-Wittenberg Bakterielles System zum Proteintransport in eukaryontische Zellen
AU2005224324B2 (en) 2004-03-17 2009-12-24 Basf Plant Science Gmbh Improved constructs for marker excision based on dual-function selection marker
EP1591521A1 (en) 2004-04-30 2005-11-02 Cellectis I-Dmo I derivatives with enhanced activity at 37 degrees C and use thereof
US20080131962A1 (en) 2006-05-25 2008-06-05 Sangamo Biosciences, Inc. Engineered cleavage half-domains
AU2005287547B2 (en) * 2004-09-23 2010-09-02 Basf Plant Science Gmbh Recombination cassettes and methods for sequence excision in plants
WO2007034262A1 (en) 2005-09-19 2007-03-29 Cellectis Heterodimeric meganucleases and use thereof
US8148607B2 (en) 2005-04-04 2012-04-03 Bayer Cropscience N.V. Methods and means for removal of a selected DNA sequence
CA2625031C (en) 2005-10-13 2016-07-19 Monsanto Technology Llc Methods for producing hybrid seed
US7601566B2 (en) 2005-10-18 2009-10-13 Semiconductor Energy Laboratory Co., Ltd. Semiconductor device and manufacturing method thereof
DK2484758T3 (da) 2005-10-18 2014-01-06 Prec Biosciences Rationelt konstruerede meganucleaser med ændret sekvensspecificitet og DNA-bindingsaffinitet
WO2007093836A1 (en) 2006-02-13 2007-08-23 Cellectis Meganuclease variants cleaving a dna target sequence from a xp gene and uses thereof
US8273956B2 (en) 2006-05-18 2012-09-25 Biogemma S.A.S. Method for performing homologous recombination in plants
KR100741255B1 (ko) 2006-07-14 2007-07-19 고려대학교 산학협력단 식물 호르몬 자스몬산 및 에틸렌 생합성 저해 관련애기장대 AtLEJ1 유전자 및 이를 이용한 웅성불임식물체 제조방법
ES2532002T3 (es) 2006-08-11 2015-03-23 Dow Agrosciences Llc Recombinación homóloga mediada por nucleasas con dedos de zinc
CA2664414C (en) 2006-09-28 2016-07-12 Bayer Bioscience N.V. Methods and means for removal of a selected dna sequence
WO2009001159A1 (en) 2007-06-25 2008-12-31 Cellectis Method for enhancing the cleavage activity of i-crei derived meganucleases
MX2009006303A (es) 2006-12-14 2009-10-21 Dow Agrosciences Llc Proteinas de dedo de zinc no canonicas optimizadas.
WO2008093152A1 (en) 2007-02-01 2008-08-07 Cellectis Obligate heterodimer meganucleases and uses thereof
CA2678526A1 (en) 2007-02-19 2008-08-28 Cellectis Laglidadg homing endonuclease variants having novel substrate specificity and use thereof
CN101889088B (zh) 2007-05-31 2014-08-06 巴斯夫植物科学有限公司 从植物基因组中切除核酸序列的方法
CA2689345C (en) 2007-06-05 2017-07-11 Bayer Bioscience N.V. Methods and means for exact replacement of target dna in eukaryotic organisms
CN101784658A (zh) 2007-06-06 2010-07-21 赛莱克蒂斯公司 增强来自I-CreI的大范围核酸酶的切割活性的方法
DK2205749T3 (en) 2007-09-27 2016-08-22 Dow Agrosciences Llc MODIFIED PROTEINS zinc finger, which target the 5-enolpyruvylshikimate-3-phosphate synthase genes
US20090197775A1 (en) 2007-10-08 2009-08-06 Eppendorf Ag Nuclease on chip
ES2732735T3 (es) 2007-10-31 2019-11-25 Prec Biosciences Inc Meganucleasas monocatenarias diseñadas racionalmente con secuencias de reconocimiento no palindrómicas
EP2215252A4 (en) 2007-12-07 2011-01-26 Prec Biosciences Inc MEGANUCLEASES DESIGNED RATIONALLY WITH IDENTIFICATION SEQUENCES FOUND IN HUMAN GENOME DNAASE HYPERSENSIVE REGIONS
WO2009074842A1 (en) 2007-12-13 2009-06-18 Cellectis Improved chimeric meganuclease enzymes and uses thereof
WO2009101625A2 (en) 2008-02-12 2009-08-20 Ramot At Tel-Aviv University Ltd. Method for searching for homing endonucleases, their genes and their targets
WO2009114321A2 (en) 2008-03-11 2009-09-17 Precision Biosciencs, Inc. Rationally-designed meganucleases for maize genome engineering
DK2268129T3 (en) 2008-04-21 2015-09-28 Danziger Innovations Ltd PLANTEVIRUSEKSPRESSIONSVEKTORER AND USE THEREOF FOR GENERATING GENOTYPEVARIATIONER into plant genomes
EP2279250A4 (en) 2008-04-28 2011-10-12 Prec Biosciences Inc Fusion Molecules of DNA Binding Proteins with Rational Design and Effects Domain
WO2010001189A1 (en) 2008-07-03 2010-01-07 Cellectis The crystal structure of i-dmoi in complex with its dna target, improved chimeric meganucleases and uses thereof
EP2206723A1 (en) 2009-01-12 2010-07-14 Bonas, Ulla Modular DNA-binding domains
US20110294217A1 (en) 2009-02-12 2011-12-01 Fred Hutchinson Cancer Research Center Dna nicking enzyme from a homing endonuclease that stimulates site-specific gene conversion
KR20100133319A (ko) 2009-06-11 2010-12-21 주식회사 툴젠 표적 특이적인 게놈의 재배열을 위한 표적 특이적 뉴클레아제 및 이의 용도
JP5780596B2 (ja) 2009-10-26 2015-09-16 国立研究開発法人農業生物資源研究所 遺伝的に改変された植物細胞の製造方法
AU2010325563B2 (en) 2009-11-27 2017-02-02 Basf Plant Science Company Gmbh Chimeric endonucleases and uses thereof
WO2011064751A1 (en) 2009-11-27 2011-06-03 Basf Plant Science Company Gmbh Chimeric endonucleases and uses thereof
BR112012012588B1 (pt) 2009-11-27 2019-03-26 Basf Plant Science Company Gmbh Endonuclease, método para recombinação homóloga de polinucleotídeos e método para mutação direcionada de polinucleotídeos
SG181601A1 (en) 2009-12-10 2012-07-30 Univ Minnesota Tal effector-mediated dna modification
WO2011078662A1 (en) 2009-12-21 2011-06-30 Keygene N.V. Dsrna for improved genetic modification of plant dna
US20110203012A1 (en) 2010-01-21 2011-08-18 Dotson Stanton B Methods and compositions for use of directed recombination in plant breeding
DK2525650T3 (en) 2010-01-22 2017-07-03 Dow Agrosciences Llc MANIPULATED PLANTS FOR GENTARGETING IN PLANTS
GB201009732D0 (en) * 2010-06-10 2010-07-21 Gene Bridges Gmbh Direct cloning

Also Published As

Publication number Publication date
WO2013102875A1 (en) 2013-07-11
US20150150160A1 (en) 2015-05-28
EP2800810B1 (en) 2018-11-28
EP2800810A4 (en) 2015-09-16
BR112014016682A8 (pt) 2017-07-04
EP2612918A1 (en) 2013-07-10
CA2857934A1 (en) 2013-07-11
EP2800810A1 (en) 2014-11-12
US10876135B2 (en) 2020-12-29

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]
B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]
B350 Update of information on the portal [chapter 15.35 patent gazette]