BR112014005858A2 - inibidores de fosfatidilinositol 3-quinase para tratamento de câncer - Google Patents

inibidores de fosfatidilinositol 3-quinase para tratamento de câncer

Info

Publication number
BR112014005858A2
BR112014005858A2 BR112014005858A BR112014005858A BR112014005858A2 BR 112014005858 A2 BR112014005858 A2 BR 112014005858A2 BR 112014005858 A BR112014005858 A BR 112014005858A BR 112014005858 A BR112014005858 A BR 112014005858A BR 112014005858 A2 BR112014005858 A2 BR 112014005858A2
Authority
BR
Brazil
Prior art keywords
phosphatidylinositol
kinase inhibitors
cancer treatment
cancer
treatment
Prior art date
Application number
BR112014005858A
Other languages
English (en)
Inventor
Decillis Arthur
Thomas Emmons Gary
Lager Joanne
Ruiz Soto Rodrigo
Original Assignee
Exelixis Inc
Sanofi Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Exelixis Inc, Sanofi Sa filed Critical Exelixis Inc
Publication of BR112014005858A2 publication Critical patent/BR112014005858A2/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4196—1,2,4-Triazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/498—Pyrazines or piperazines ortho- and peri-condensed with carbocyclic ring systems, e.g. quinoxaline, phenazine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
BR112014005858A 2011-09-14 2012-09-14 inibidores de fosfatidilinositol 3-quinase para tratamento de câncer BR112014005858A2 (pt)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201161534836P 2011-09-14 2011-09-14
US201161543529P 2011-10-05 2011-10-05
US201161562670P 2011-11-22 2011-11-22
PCT/US2012/055387 WO2013040337A1 (en) 2011-09-14 2012-09-14 Phosphatidylinositol 3-kinase inhibitors for the treatment of cancer

Publications (1)

Publication Number Publication Date
BR112014005858A2 true BR112014005858A2 (pt) 2017-06-13

Family

ID=46940622

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112014005858A BR112014005858A2 (pt) 2011-09-14 2012-09-14 inibidores de fosfatidilinositol 3-quinase para tratamento de câncer

Country Status (10)

Country Link
EP (1) EP2755654A1 (pt)
KR (1) KR20140077911A (pt)
AU (1) AU2012308414A1 (pt)
BR (1) BR112014005858A2 (pt)
CA (1) CA2848724A1 (pt)
IL (1) IL231448A0 (pt)
IN (1) IN2014CN02671A (pt)
TW (1) TW201325592A (pt)
UY (1) UY34339A (pt)
WO (1) WO2013040337A1 (pt)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113754565B (zh) * 2021-11-09 2022-02-22 南京威凯尔生物医药科技有限公司 一种连续流微反应器中制备沙库巴曲中间体的方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4107288A (en) 1974-09-18 1978-08-15 Pharmaceutical Society Of Victoria Injectable compositions, nanoparticles useful therein, and process of manufacturing same
US5145684A (en) 1991-01-25 1992-09-08 Sterling Drug Inc. Surface modified drug nanoparticles
US7019002B2 (en) 2001-12-11 2006-03-28 Pharmacia & Upjohn, S.P.A. Pyridopyrimidinones derivatives as telomerase inhibitors
KR101538412B1 (ko) 2005-10-07 2015-07-22 엑셀리시스, 인코포레이티드 ＰＩ３Ｋα의 피리도피리미디논 억제제
KR101396783B1 (ko) * 2005-10-07 2014-05-21 엑셀리시스, 인코포레이티드 포스파티딜이노시톨 3-키나아제 억제제 및 이의 사용 방법
WO2007044481A1 (en) 2005-10-07 2007-04-19 Basf Corporation Clearcoat coating composition
MY150797A (en) * 2007-04-11 2014-02-28 Exelixis Inc Combination therapies comprising quinaxoline inhibitors of pi3k-alpha for use in the treatment of cancer
WO2010146391A1 (en) * 2009-06-15 2010-12-23 Generics [Uk] Limited Regioselective synthesis of letrozole
WO2012065057A2 (en) * 2010-11-12 2012-05-18 Exelixis, Inc. Phosphatidylinositol 3-kinase inhibitors and methods of their use

Also Published As

Publication number Publication date
UY34339A (es) 2013-04-30
IL231448A0 (en) 2014-04-30
WO2013040337A1 (en) 2013-03-21
EP2755654A1 (en) 2014-07-23
IN2014CN02671A (pt) 2015-07-03
CA2848724A1 (en) 2013-03-21
AU2012308414A1 (en) 2014-05-01
WO2013040337A9 (en) 2014-04-03
KR20140077911A (ko) 2014-06-24
TW201325592A (zh) 2013-07-01

Similar Documents

Publication Publication Date Title
SMT201700111B (it) Eterociclilammine come inibitori di pi3k
HK1207861A1 (en) Substituted cycloalkenopyrazoles as bub1 inhibitors for the treatment of cancer bub1
HK1223911A1 (zh) 磷脂醯肌醇 -激酶抑制劑
BR112014032105A2 (pt) método para o tratamento de câncer
IL232128B (en) Tor kinase inhibitors for cancer treatment
PT3418281T (pt) Pirazolo[1,5-a]pirimidinas úteis como inibidores da quinase atr para o tratamento de doenças de cancro
EP3030323A4 (en) Kdm1a inhibitors for the treatment of disease
BR112013010157A2 (pt) inibidores do ibat para o tratamento de doenças do fígado
CO6960110A1 (es) Composición aditiva para fluidos de tratamiento de pozos
BR112015004373A2 (pt) implante adequado para osteotomia do calcâneo
BR112014028424A2 (pt) compostos de pirimidina para o tratamento de câncer
PL2753334T3 (pl) Aktywowane przez fap inhibitory proteasomu do leczenia guzów litych
BR112014007603A2 (pt) métodos de tratamento do câncer
SMT201600114B (it) Inibitori di beta-secretasi
BR112015004548A2 (pt) inibidores de serina/treonina para tratamento de doenças hiperproliferativas
BR112014031806A2 (pt) método para tratamento de câncer positivo para gd2
HK1193823A1 (zh) 用於治療癌症的作為 -激酶抑制劑的苯並吡喃酮化合物
BR112015006512A2 (pt) composição para tratar tecidos biológicos danificados
BR112014029487A2 (pt) método para o tratamento cosmético
BR112013031702A2 (pt) 1-piperazino-3-fenil indanos deuterados para o tratamento de esquizofrenia
BR112013028890A2 (pt) composições e métodos para o tratamento de câncer
HK1205500A1 (en) Kinase inhibitors for the treatment of cancer
EP2897607A4 (en) BETA-HYDROLASE INHIBITORS FOR THE TREATMENT OF CANCER
GB201214877D0 (en) Compounds for treatments of tumors
BR112013007841A2 (pt) derivador de 4- (metilaminofenoxi) piridina - 3 - yl - benzamida para tratamento de câncer

Legal Events

Date Code Title Description
B11A Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing
B11N Dismissal: publication cancelled [chapter 11.14 patent gazette]
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]
B08H Application fees: decision cancelled [chapter 8.8 patent gazette]
B350 Update of information on the portal [chapter 15.35 patent gazette]