IN2014CN02671A - - Google Patents

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Publication number
IN2014CN02671A
IN2014CN02671A IN2671CHN2014A IN2014CN02671A IN 2014CN02671 A IN2014CN02671 A IN 2014CN02671A IN 2671CHN2014 A IN2671CHN2014 A IN 2671CHN2014A IN 2014CN02671 A IN2014CN02671 A IN 2014CN02671A
Authority
IN
India
Prior art keywords
formula
compound
administering
treating
combination
Prior art date
Application number
Other languages
English (en)
Inventor
Arthur Decillis
Soto Rodrigo Ruiz
Gary Thomas Emmons
Joanne Lager
Original Assignee
Exelixis Inc
Sanofi Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Exelixis Inc, Sanofi Sa filed Critical Exelixis Inc
Publication of IN2014CN02671A publication Critical patent/IN2014CN02671A/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/41961,2,4-Triazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/498Pyrazines or piperazines ortho- and peri-condensed with carbocyclic ring systems, e.g. quinoxaline, phenazine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IN2671CHN2014 2011-09-14 2012-09-14 IN2014CN02671A (pt)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201161534836P 2011-09-14 2011-09-14
US201161543529P 2011-10-05 2011-10-05
US201161562670P 2011-11-22 2011-11-22
PCT/US2012/055387 WO2013040337A1 (en) 2011-09-14 2012-09-14 Phosphatidylinositol 3-kinase inhibitors for the treatment of cancer

Publications (1)

Publication Number Publication Date
IN2014CN02671A true IN2014CN02671A (pt) 2015-07-03

Family

ID=46940622

Family Applications (1)

Application Number Title Priority Date Filing Date
IN2671CHN2014 IN2014CN02671A (pt) 2011-09-14 2012-09-14

Country Status (10)

Country Link
EP (1) EP2755654A1 (pt)
KR (1) KR20140077911A (pt)
AU (1) AU2012308414A1 (pt)
BR (1) BR112014005858A2 (pt)
CA (1) CA2848724A1 (pt)
IL (1) IL231448A0 (pt)
IN (1) IN2014CN02671A (pt)
TW (1) TW201325592A (pt)
UY (1) UY34339A (pt)
WO (1) WO2013040337A1 (pt)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113754565B (zh) * 2021-11-09 2022-02-22 南京威凯尔生物医药科技有限公司 一种连续流微反应器中制备沙库巴曲中间体的方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4107288A (en) 1974-09-18 1978-08-15 Pharmaceutical Society Of Victoria Injectable compositions, nanoparticles useful therein, and process of manufacturing same
US5145684A (en) 1991-01-25 1992-09-08 Sterling Drug Inc. Surface modified drug nanoparticles
US7019002B2 (en) 2001-12-11 2006-03-28 Pharmacia & Upjohn, S.P.A. Pyridopyrimidinones derivatives as telomerase inhibitors
WO2007044481A1 (en) 2005-10-07 2007-04-19 Basf Corporation Clearcoat coating composition
EA024305B1 (ru) * 2005-10-07 2016-09-30 Экселиксис, Инк. Ингибиторы фосфатидилинозит-3-киназы и их применение
KR20140105621A (ko) 2005-10-07 2014-09-01 엑셀리시스, 인코포레이티드 PI3Kα의 피리도피리미디논 억제제
RS53020B (en) * 2007-04-11 2014-04-30 Exelixis Inc. COMBINED THERAPY CONTAINING HINOXALINE PI3K-ALPHA INHIBITOR FOR USE IN CANCER TREATMENT
WO2010146391A1 (en) * 2009-06-15 2010-12-23 Generics [Uk] Limited Regioselective synthesis of letrozole
WO2012065057A2 (en) * 2010-11-12 2012-05-18 Exelixis, Inc. Phosphatidylinositol 3-kinase inhibitors and methods of their use

Also Published As

Publication number Publication date
UY34339A (es) 2013-04-30
KR20140077911A (ko) 2014-06-24
WO2013040337A1 (en) 2013-03-21
IL231448A0 (en) 2014-04-30
AU2012308414A1 (en) 2014-05-01
BR112014005858A2 (pt) 2017-06-13
WO2013040337A9 (en) 2014-04-03
CA2848724A1 (en) 2013-03-21
TW201325592A (zh) 2013-07-01
EP2755654A1 (en) 2014-07-23

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