BR112014000637A2 - diagnóstico do mal de alzheimer - Google Patents
diagnóstico do mal de alzheimerInfo
- Publication number
- BR112014000637A2 BR112014000637A2 BR112014000637A BR112014000637A BR112014000637A2 BR 112014000637 A2 BR112014000637 A2 BR 112014000637A2 BR 112014000637 A BR112014000637 A BR 112014000637A BR 112014000637 A BR112014000637 A BR 112014000637A BR 112014000637 A2 BR112014000637 A2 BR 112014000637A2
- Authority
- BR
- Brazil
- Prior art keywords
- alzheimer
- diagnosis
- disease
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
- G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/91—Transferases (2.)
- G01N2333/912—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
- G01N2333/91205—Phosphotransferases in general
- G01N2333/9121—Phosphotransferases in general with an alcohol group as acceptor (2.7.1), e.g. general tyrosine, serine or threonine kinases
- G01N2333/91215—Phosphotransferases in general with an alcohol group as acceptor (2.7.1), e.g. general tyrosine, serine or threonine kinases with a definite EC number (2.7.1.-)
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/28—Neurological disorders
- G01N2800/2814—Dementia; Cognitive disorders
- G01N2800/2821—Alzheimer
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/50—Determining the risk of developing a disease
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Analytical Chemistry (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Pathology (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Cell Biology (AREA)
- General Physics & Mathematics (AREA)
- Medicinal Chemistry (AREA)
- Food Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB1112246.2A GB201112246D0 (en) | 2011-07-15 | 2011-07-15 | Diagnosis of alzheimer's disease |
| PCT/GB2012/051693 WO2013011294A2 (en) | 2011-07-15 | 2012-07-16 | Diagnosis of alzheimer's disease |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR112014000637A2 true BR112014000637A2 (pt) | 2017-06-13 |
Family
ID=44586710
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112014000637A BR112014000637A2 (pt) | 2011-07-15 | 2012-07-16 | diagnóstico do mal de alzheimer |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US20140295425A1 (pt) |
| EP (1) | EP2732290B1 (pt) |
| JP (1) | JP2014521315A (pt) |
| KR (1) | KR20140064779A (pt) |
| CN (1) | CN103765218A (pt) |
| AU (1) | AU2012285561A1 (pt) |
| BR (1) | BR112014000637A2 (pt) |
| CA (1) | CA2840797A1 (pt) |
| GB (1) | GB201112246D0 (pt) |
| IL (1) | IL230441A0 (pt) |
| MX (1) | MX2013015409A (pt) |
| RU (1) | RU2014105558A (pt) |
| WO (1) | WO2013011294A2 (pt) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2015184107A1 (en) | 2014-05-28 | 2015-12-03 | Georgetown University | Genetic markers for memory loss |
| CN105018484B (zh) * | 2015-07-31 | 2017-10-13 | 北京泱深生物信息技术有限公司 | Crtap基因及其表达产物作为阿尔茨海默病的诊治靶标 |
| CN106018827B (zh) * | 2016-05-30 | 2018-01-16 | 深圳大学 | 一种阿尔茨海默症检测标志物及其检测方法 |
| BR112019014841A2 (pt) | 2017-01-23 | 2020-04-28 | Regeneron Pharma | rna guia, uso do rna guia, rna antissentido, sirna ou shrna, uso do rna antissentido, do sirna ou do shrna, ácido nucleico isolado, vetor, composição, célula, e, métodos para modificar um gene hsd17b13 em uma célula, para diminuir a expressão de um gene hsd17b13 em uma célula, para modificar uma célula e para tratar um indivíduo que não é portador da variante de hsd17b13 |
| KR102577154B1 (ko) * | 2017-03-31 | 2023-09-12 | 뉴로디아그노스틱스 엘엘씨 | 알츠하이머 질환에 대한 림프구-기반 PKCε 시험 |
| SG11201909453RA (en) | 2017-04-11 | 2019-11-28 | Regeneron Pharma | Assays for screening activity of modulators of members of the hydroxysteroid (17-beta) dehydrogenase (hsd17b) family |
| SE543211C2 (en) * | 2017-06-29 | 2020-10-27 | Mabtech Production Ab | Method and system for analyzing Fluorospot assays |
| WO2019075181A1 (en) | 2017-10-11 | 2019-04-18 | Regeneron Pharmaceuticals, Inc. | INHIBITION OF HSD17B13 IN THE TREATMENT OF HEPATIC DISEASE IN PATIENTS EXPRESSING PNPLA3 I148M VARIATION |
| CN115078570B (zh) * | 2022-05-30 | 2024-05-28 | 郑州大学第一附属医院 | Tau蛋白639位硫氰酸氨基酸修饰在快速质谱法检测阿尔茨海默症中的应用 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20030092019A1 (en) * | 2001-01-09 | 2003-05-15 | Millennium Pharmaceuticals, Inc. | Methods and compositions for diagnosing and treating neuropsychiatric disorders such as schizophrenia |
| GB0106051D0 (en) * | 2001-03-12 | 2001-05-02 | Isis Innovation | Diagnostic screens for alzheimer's disease |
| GB0117645D0 (en) * | 2001-07-19 | 2001-09-12 | Isis Innovation | Therapeutic stratergies for prevention and treatment of alzheimers disease |
| WO2009105549A2 (en) * | 2008-02-19 | 2009-08-27 | Oncomethylome Sciences Sa | Detection and prognosis of lung cancer |
| GB0912394D0 (en) * | 2009-07-16 | 2009-08-26 | Univ Birmingham | Screening methods |
-
2011
- 2011-07-15 GB GBGB1112246.2A patent/GB201112246D0/en not_active Ceased
-
2012
- 2012-07-16 CN CN201280035133.1A patent/CN103765218A/zh active Pending
- 2012-07-16 EP EP12738590.4A patent/EP2732290B1/en not_active Not-in-force
- 2012-07-16 MX MX2013015409A patent/MX2013015409A/es not_active Application Discontinuation
- 2012-07-16 US US14/233,113 patent/US20140295425A1/en not_active Abandoned
- 2012-07-16 AU AU2012285561A patent/AU2012285561A1/en not_active Abandoned
- 2012-07-16 WO PCT/GB2012/051693 patent/WO2013011294A2/en active Application Filing
- 2012-07-16 JP JP2014519634A patent/JP2014521315A/ja active Pending
- 2012-07-16 CA CA2840797A patent/CA2840797A1/en not_active Abandoned
- 2012-07-16 KR KR1020147003651A patent/KR20140064779A/ko not_active Application Discontinuation
- 2012-07-16 BR BR112014000637A patent/BR112014000637A2/pt not_active Application Discontinuation
- 2012-07-16 RU RU2014105558/15A patent/RU2014105558A/ru unknown
-
2014
- 2014-01-13 IL IL230441A patent/IL230441A0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| IL230441A0 (en) | 2014-03-31 |
| GB201112246D0 (en) | 2011-08-31 |
| WO2013011294A3 (en) | 2013-04-04 |
| CN103765218A (zh) | 2014-04-30 |
| EP2732290A2 (en) | 2014-05-21 |
| JP2014521315A (ja) | 2014-08-28 |
| AU2012285561A1 (en) | 2014-01-09 |
| MX2013015409A (es) | 2014-03-31 |
| WO2013011294A2 (en) | 2013-01-24 |
| KR20140064779A (ko) | 2014-05-28 |
| US20140295425A1 (en) | 2014-10-02 |
| CA2840797A1 (en) | 2013-01-24 |
| EP2732290B1 (en) | 2016-05-25 |
| RU2014105558A (ru) | 2015-08-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B11A | Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing | ||
| B11N | Dismissal: publication cancelled [chapter 11.14 patent gazette] | ||
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] | ||
| B08H | Application fees: decision cancelled [chapter 8.8 patent gazette] | ||
| B350 | Update of information on the portal [chapter 15.35 patent gazette] |