BR112013026951A2 - método e sensor ótico para a detecção de moléculas de uma substância específica - Google Patents

método e sensor ótico para a detecção de moléculas de uma substância específica

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Publication number
BR112013026951A2
BR112013026951A2 BR112013026951A BR112013026951A BR112013026951A2 BR 112013026951 A2 BR112013026951 A2 BR 112013026951A2 BR 112013026951 A BR112013026951 A BR 112013026951A BR 112013026951 A BR112013026951 A BR 112013026951A BR 112013026951 A2 BR112013026951 A2 BR 112013026951A2
Authority
BR
Brazil
Prior art keywords
resonator
sym
sensor
optical
wavelength
Prior art date
Application number
BR112013026951A
Other languages
English (en)
Inventor
Daniel Pergande
Helmut Heidrich
Peter Lützow
Wolfgang Schade
Original Assignee
Fraunhofer Ges Forschung
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fraunhofer Ges Forschung filed Critical Fraunhofer Ges Forschung
Publication of BR112013026951A2 publication Critical patent/BR112013026951A2/pt

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Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/255Details, e.g. use of specially adapted sources, lighting or optical systems
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • G01N21/7703Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator using reagent-clad optical fibres or optical waveguides
    • G01N21/7746Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator using reagent-clad optical fibres or optical waveguides the waveguide coupled to a cavity resonator
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/27Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands using photo-electric detection ; circuits for computing concentration
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/1717Systems in which incident light is modified in accordance with the properties of the material investigated with a modulation of one or more physical properties of the sample during the optical investigation, e.g. electro-reflectance
    • G01N2021/1731Temperature modulation
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • G01N2021/7769Measurement method of reaction-produced change in sensor
    • G01N2021/7789Cavity or resonator
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/31Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
    • G01N21/39Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using tunable lasers

Landscapes

  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Pathology (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Plasma & Fusion (AREA)
  • Theoretical Computer Science (AREA)
  • Mathematical Physics (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)

Abstract

método para a detecção de moléculas e sensor ótico a invenção refere-se a um método para a detecção de moléculas de uma substâncias específica, por meio de um sensorótico. este método compreende as etapas de - colocar o sensor em contato com um fluido a ser analisado, - acoplar uma luz de um primeiro comprimento de onda (sym~ 1~) em um ressonador ótico (3) do sensor, o ressoador (3) sendo coberto, pelo menos parcialmente, com uma camada ativa de um material de revestimento para adsorver seletivamente um grupo de substâncias, - acoplar a luz de um segundo comprimento de onda (sym~ 2~) no mesmo ressonador (3) ou a um segundo ressonador ótico (3') do sensor, o sensor, o segundo ressoador (3') sendo coberto, pelo menos parcialmente, com uma camada ativa do mesmo material da cobertura - detectar, para cada um dos primeiro e segundo comprimento de onda (sym~ 1~, sym~ 2~), um sinal ótico acoplado ao percurso ótico que contém o respectivo ressonador (3, 3'), - variar um percurso ótico do respectivo ressonador (3, 3') ou o respectivo comprimento de onda (sym~ 1~, sym~ 2~) de tal modo que um intervalo que compreende pelo menos uma ressonância do respectivo ressonador (3, 3') é digitalizada, e - detectar um alargamento desta ressonância indicando uma absorção da luz introduzida no respectivo ressonador (3, 3') por moléculas acumuladas na camada ativa deste ressoador (3, 3'). a invenção também diz respeito a um sensor ótico projetado para executar este método.
BR112013026951A 2011-04-21 2012-04-19 método e sensor ótico para a detecção de moléculas de uma substância específica BR112013026951A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP11075072A EP2515099A1 (en) 2011-04-21 2011-04-21 Method of detecting molecules and optical sensor
PCT/EP2012/001175 WO2012143072A1 (en) 2011-04-21 2012-04-19 Method of detecting molecules and optical sensor

Publications (1)

Publication Number Publication Date
BR112013026951A2 true BR112013026951A2 (pt) 2017-01-10

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
BR112013026951A BR112013026951A2 (pt) 2011-04-21 2012-04-19 método e sensor ótico para a detecção de moléculas de uma substância específica

Country Status (5)

Country Link
US (1) US9097648B2 (pt)
EP (2) EP2515099A1 (pt)
CN (1) CN103620391B (pt)
BR (1) BR112013026951A2 (pt)
WO (1) WO2012143072A1 (pt)

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EP2515099A1 (en) 2011-04-21 2012-10-24 Fraunhofer Gesellschaft zur Förderung der angewandten Wissenschaft E.V. Method of detecting molecules and optical sensor
DE102012208865B4 (de) * 2012-05-25 2016-09-29 Secopta Gmbh Optischer Sensor und Verfahren zur Detektion einer Substanz
DE102012214440B3 (de) * 2012-08-14 2013-10-24 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Planaroptisches Element, Sensorelement und Verfahren zu deren Herstellung
EP2735862B1 (en) * 2012-11-21 2020-01-15 Fraunhofer Gesellschaft zur Förderung der angewandten Forschung E.V. Optical sensor arrangement and method for measuring an observable
EP2738547A1 (en) * 2012-11-29 2014-06-04 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung Optical sensor arrangement and method for measuring an observable
US9846060B2 (en) 2013-03-28 2017-12-19 Frauhofer-Gesellschaft Zur Foerderung Der Angewandten Forschung E.V. Optical sensor arrangement and method for measuring an observable
CN103529520B (zh) * 2013-10-21 2015-10-28 天津大学 基于微流体调控的可调谐多路波分复用装置和复用方法
WO2015090426A1 (de) * 2013-12-19 2015-06-25 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Integrierte sensorauswerteschaltung und verfahren zum betrieb derselben
US9655519B2 (en) 2014-03-21 2017-05-23 Hypermed Imaging, Inc. Systems and methods for performing an imaging test under constrained conditions
CA2943502C (en) 2014-03-21 2022-05-31 Hypermed Imaging, Inc. Compact light sensor
DE102015010998A1 (de) * 2015-08-21 2017-02-23 Bartec Benke Gmbh Optischer Sensor zur Messung mindestens eines charakteristischen Merkmals eines flüssigen und/oder gasförmigen Mediums
DE102015122306A1 (de) * 2015-12-18 2017-06-22 RUHR-UNIVERSITäT BOCHUM Sensor zur ortsauflösenden Erfassung von zumindest einer Einwirkung auf den Sensor
EP3220113B1 (en) * 2016-03-16 2019-05-01 Centre National de la Recherche Scientifique - CNRS - Optomechanical transducer for terahertz electromagnetic waves
WO2017201093A1 (en) 2016-05-17 2017-11-23 Hypermed Imaging, Inc. Hyperspectral imager coupled with indicator molecule tracking
JP7211017B2 (ja) * 2018-11-02 2023-01-24 株式会社デンソー 光フィルタ、それを用いたレーザ光源および光送受信装置
EP3671186A1 (en) * 2018-12-21 2020-06-24 IHP GmbH - Innovations for High Performance Microelectronics / Leibniz-Institut für innovative Mikroelektronik Photonic sensor chip, packaged photonic sensor device and arrangement
US11079376B1 (en) 2020-11-12 2021-08-03 United Arab Emirates University Optical analyte detector
FR3127572B1 (fr) * 2021-09-24 2023-09-08 Commissariat Energie Atomique Dispositif et procédé de détection d’espèces chimiques ou biologiques

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FI118061B (fi) * 2001-09-24 2007-06-15 Beanor Oy Menetelmä ja bioanturi analyysiä varten
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EP2515099A1 (en) 2011-04-21 2012-10-24 Fraunhofer Gesellschaft zur Förderung der angewandten Wissenschaft E.V. Method of detecting molecules and optical sensor

Also Published As

Publication number Publication date
CN103620391B (zh) 2016-03-23
CN103620391A (zh) 2014-03-05
EP2515099A1 (en) 2012-10-24
EP2699891B1 (en) 2015-06-10
US20140118741A1 (en) 2014-05-01
US9097648B2 (en) 2015-08-04
WO2012143072A1 (en) 2012-10-26
EP2699891A1 (en) 2014-02-26

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Legal Events

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B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B11B Dismissal acc. art. 36, par 1 of ipl - no reply within 90 days to fullfil the necessary requirements