BR112013008856A2 - compostos de sulfonamida e métodos pra fazer e usar os mesmos - Google Patents
compostos de sulfonamida e métodos pra fazer e usar os mesmosInfo
- Publication number
- BR112013008856A2 BR112013008856A2 BR112013008856A BR112013008856A BR112013008856A2 BR 112013008856 A2 BR112013008856 A2 BR 112013008856A2 BR 112013008856 A BR112013008856 A BR 112013008856A BR 112013008856 A BR112013008856 A BR 112013008856A BR 112013008856 A2 BR112013008856 A2 BR 112013008856A2
- Authority
- BR
- Brazil
- Prior art keywords
- making
- methods
- sulfonamide compounds
- sulfonamide
- compounds
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- C07D333/66—Nitrogen atoms not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- C07D333/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
- A61K31/381—Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US39210810P | 2010-10-12 | 2010-10-12 | |
| US42005010P | 2010-12-06 | 2010-12-06 | |
| PCT/US2011/055987 WO2012051318A1 (en) | 2010-10-12 | 2011-10-12 | Sulphonamide compounds and methods of making and using same |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR112013008856A2 true BR112013008856A2 (pt) | 2016-06-21 |
Family
ID=44903376
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112013008856A BR112013008856A2 (pt) | 2010-10-12 | 2011-10-12 | compostos de sulfonamida e métodos pra fazer e usar os mesmos |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US9221787B2 (pt) |
| EP (1) | EP2627632A1 (pt) |
| JP (1) | JP5913333B2 (pt) |
| KR (1) | KR20140026330A (pt) |
| CN (1) | CN103370307B (pt) |
| AU (1) | AU2011316550A1 (pt) |
| BR (1) | BR112013008856A2 (pt) |
| CA (1) | CA2814413A1 (pt) |
| MX (1) | MX339201B (pt) |
| WO (1) | WO2012051318A1 (pt) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8642650B2 (en) | 2008-12-04 | 2014-02-04 | Zafgen, Inc. | Methods of treating an overweight or obese subject |
| WO2010065877A2 (en) | 2008-12-04 | 2010-06-10 | Zafgen Corporation | Methods of treating an overweight or obese subject |
| MX337575B (es) | 2009-10-09 | 2016-03-10 | Zafgen Corp | Compuestos de sulfona y métodos para lafabricación y uso de éstos. |
| WO2011085198A1 (en) | 2010-01-08 | 2011-07-14 | Zafgen Corporation | Metap-2 inhibitor for use in treating benign prostatic hypertrophy (bph) |
| MX343135B (es) | 2010-01-08 | 2016-10-25 | Zafgen Corp * | Compuestos de tipo fumagilol y métodos de realización y uso de los mismos. |
| US20130266578A1 (en) | 2010-04-07 | 2013-10-10 | Thomas E. Hughes | Methods of treating an overweight subject |
| MX2013000836A (es) | 2010-07-22 | 2013-09-26 | Zafgen Inc | Compuestos triciclicos y metodos para elaborar y usar los mismos. |
| KR20140009273A (ko) | 2010-11-29 | 2014-01-22 | 자프겐 인크. | 6-o-(4-디메틸아미노에톡시)신나모일 푸마길롤의 비-일일 투여를 사용하는 비만의 치료 |
| EP2668169B1 (en) | 2011-01-26 | 2017-11-15 | Zafgen, Inc. | Tetrazole compounds and methods of making and using same |
| AU2012225531B2 (en) | 2011-03-08 | 2017-03-30 | Zafgen, Inc | Oxaspiro (2.5) octane derivatives and analogs |
| JP6062423B2 (ja) | 2011-05-06 | 2017-01-18 | ザフゲン，インコーポレイテッド | 部分飽和三環式化合物ならびにその製造および使用方法 |
| MX343688B (es) | 2011-05-06 | 2016-11-16 | Zafgen Inc | Compuestos tricíclicos de sulfonamida y pirazolo y métodos para su fabricación y uso. |
| BR112013028665A2 (pt) | 2011-05-06 | 2016-09-06 | Zafgen Inc | compostos de sulfonamida tricíclicos e métodos para fazer e usar os mesmos |
| EP2763671A2 (en) | 2011-10-03 | 2014-08-13 | Zafgen, Inc. | Methods of treating age related disorders |
| BR112014017673A8 (pt) | 2012-01-18 | 2017-07-11 | Zafgen Inc | Compostos de sulfonamida tricíclicos e métodos para fazer e usar os mesmos |
| MX2014008705A (es) | 2012-01-18 | 2015-02-05 | Zafgen Inc | Compuestos tricíclicos de sulfona y métodos para elaborarlos y utilizarlos. |
| EP2846792B1 (en) | 2012-05-08 | 2018-08-15 | Zafgen, Inc. | Treating hypothalamic obesity with metap2 inhibitors |
| US9573918B2 (en) | 2012-05-09 | 2017-02-21 | Zafgen, Inc. | Fumigillol compounds and methods of making and using same |
| EP2917197B1 (en) | 2012-11-05 | 2019-06-05 | Zafgen, Inc. | Tricyclic compounds and methods of making and using same |
| CN104918928A (zh) | 2012-11-05 | 2015-09-16 | 扎夫根股份有限公司 | 三环化合物及其制备方法和用途 |
| KR20150079951A (ko) | 2012-11-05 | 2015-07-08 | 자프겐 인크. | 간 질환의 치료 방법 |
| CN105228610A (zh) | 2013-03-14 | 2016-01-06 | 扎夫根股份有限公司 | 治疗肾疾病和其它病症的方法 |
| KR102065329B1 (ko) | 2014-05-30 | 2020-01-13 | 다우 실리콘즈 코포레이션 | 다이아이소프로필아미노-다이실란의 합성 공정 |
| JPWO2016039403A1 (ja) * | 2014-09-11 | 2017-06-29 | 塩野義製薬株式会社 | 持続性ｈｉｖプロテアーゼ阻害剤 |
| AR105671A1 (es) | 2015-08-11 | 2017-10-25 | Zafgen Inc | Compuestos heterocíclicos de fumagillol y sus métodos de elaboración y uso |
| CN106432255A (zh) | 2015-08-11 | 2017-02-22 | 扎夫根公司 | 烟曲霉素醇螺环化合物和制备和使用其的方法 |
| IT202100022172A1 (it) * | 2021-08-23 | 2023-02-23 | Natural Acad S R L | Composizione liquida medicale per somministrazione aerea |
| WO2023212095A1 (en) * | 2022-04-27 | 2023-11-02 | The Regents Of The University Of California | Molecules that enhance extracellular vesicle release |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6551611B2 (en) * | 1995-09-28 | 2003-04-22 | Schering Aktiengesellschaft | Hormone replacement therapy method |
| US7491718B2 (en) | 2002-10-08 | 2009-02-17 | Abbott Laboratories | Sulfonamides having antiangiogenic and anticancer activity |
| DE102007020492A1 (de) | 2007-04-30 | 2008-11-06 | Grünenthal GmbH | Substituierte Sulfonamid-Derivate |
| KR20100033418A (ko) * | 2007-07-30 | 2010-03-29 | 엔싸이시브 파마슈티칼즈 인코퍼레이티드 | Ｃｃｒ9 수용체의 조절제 및 그의 사용 방법 |
| PT2227466E (pt) | 2007-11-30 | 2011-07-01 | Bayer Schering Pharma Ag | Piperidinas com substituição heteroarilo |
| WO2010065879A2 (en) * | 2008-12-04 | 2010-06-10 | Zafgen Corporation | Methods of treating an overweight or obese subject |
| MX337575B (es) | 2009-10-09 | 2016-03-10 | Zafgen Corp | Compuestos de sulfona y métodos para lafabricación y uso de éstos. |
| MX2013000836A (es) | 2010-07-22 | 2013-09-26 | Zafgen Inc | Compuestos triciclicos y metodos para elaborar y usar los mismos. |
| EP2668169B1 (en) | 2011-01-26 | 2017-11-15 | Zafgen, Inc. | Tetrazole compounds and methods of making and using same |
| BR112013028665A2 (pt) | 2011-05-06 | 2016-09-06 | Zafgen Inc | compostos de sulfonamida tricíclicos e métodos para fazer e usar os mesmos |
| JP6062423B2 (ja) | 2011-05-06 | 2017-01-18 | ザフゲン，インコーポレイテッド | 部分飽和三環式化合物ならびにその製造および使用方法 |
| MX343688B (es) | 2011-05-06 | 2016-11-16 | Zafgen Inc | Compuestos tricíclicos de sulfonamida y pirazolo y métodos para su fabricación y uso. |
-
2011
- 2011-10-12 JP JP2013533977A patent/JP5913333B2/ja active Active
- 2011-10-12 CN CN201180059472.9A patent/CN103370307B/zh not_active Expired - Fee Related
- 2011-10-12 CA CA2814413A patent/CA2814413A1/en not_active Abandoned
- 2011-10-12 US US13/878,958 patent/US9221787B2/en not_active Expired - Fee Related
- 2011-10-12 BR BR112013008856A patent/BR112013008856A2/pt not_active IP Right Cessation
- 2011-10-12 WO PCT/US2011/055987 patent/WO2012051318A1/en active Application Filing
- 2011-10-12 EP EP11773159.6A patent/EP2627632A1/en not_active Withdrawn
- 2011-10-12 AU AU2011316550A patent/AU2011316550A1/en not_active Abandoned
- 2011-10-12 KR KR1020137012153A patent/KR20140026330A/ko not_active Application Discontinuation
- 2011-10-12 MX MX2013004079A patent/MX339201B/es active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| AU2011316550A1 (en) | 2013-05-02 |
| CA2814413A1 (en) | 2012-04-19 |
| CN103370307A (zh) | 2013-10-23 |
| MX339201B (es) | 2016-05-13 |
| EP2627632A1 (en) | 2013-08-21 |
| WO2012051318A1 (en) | 2012-04-19 |
| JP2013539789A (ja) | 2013-10-28 |
| US20130217759A1 (en) | 2013-08-22 |
| US9221787B2 (en) | 2015-12-29 |
| MX2013004079A (es) | 2013-10-25 |
| WO2012051318A8 (en) | 2013-05-23 |
| CN103370307B (zh) | 2016-05-25 |
| JP5913333B2 (ja) | 2016-04-27 |
| KR20140026330A (ko) | 2014-03-05 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B08F | Application fees: application dismissed [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 4A ANUIDADE. PAGAR RESTAURACAO. |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2386 DE 27-09-2016 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013. |