BR112013007022A2 - uso de estearato de magnésio, formulação farmacêutica e inalador de pó seco - Google Patents
uso de estearato de magnésio, formulação farmacêutica e inalador de pó secoInfo
- Publication number
- BR112013007022A2 BR112013007022A2 BR112013007022A BR112013007022A BR112013007022A2 BR 112013007022 A2 BR112013007022 A2 BR 112013007022A2 BR 112013007022 A BR112013007022 A BR 112013007022A BR 112013007022 A BR112013007022 A BR 112013007022A BR 112013007022 A2 BR112013007022 A2 BR 112013007022A2
- Authority
- BR
- Brazil
- Prior art keywords
- magnesium stearate
- dry powder
- pharmaceutical formulation
- powder inhaler
- inhaler
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5015—Organic compounds, e.g. fats, sugars
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5089—Processes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Pulmonology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Otolaryngology (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP10183018.0 | 2010-09-30 | ||
| EP10183018 | 2010-09-30 | ||
| PCT/EP2011/066062 WO2012041717A1 (en) | 2010-09-30 | 2011-09-16 | Use of magnesium stearate in dry powder formulations for inhalation |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| BR112013007022A2 true BR112013007022A2 (pt) | 2016-06-14 |
| BR112013007022B1 BR112013007022B1 (pt) | 2019-10-15 |
Family
ID=43618674
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112013007022-6A BR112013007022B1 (pt) | 2010-09-30 | 2011-09-16 | Uso de estearato de magnésio |
Country Status (13)
| Country | Link |
|---|---|
| US (3) | US20120082727A1 (pt) |
| EP (1) | EP2621494B1 (pt) |
| KR (2) | KR101886987B1 (pt) |
| CN (1) | CN103298470B (pt) |
| AR (1) | AR083208A1 (pt) |
| BR (1) | BR112013007022B1 (pt) |
| CA (1) | CA2813096C (pt) |
| ES (1) | ES2704688T3 (pt) |
| HK (1) | HK1187822A1 (pt) |
| PL (1) | PL2621494T3 (pt) |
| RU (1) | RU2580890C2 (pt) |
| TR (1) | TR201901644T4 (pt) |
| WO (1) | WO2012041717A1 (pt) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9925282B2 (en) | 2009-01-29 | 2018-03-27 | The General Hospital Corporation | Cromolyn derivatives and related methods of imaging and treatment |
| GB0918249D0 (en) | 2009-10-19 | 2009-12-02 | Respivert Ltd | Compounds |
| CN104257610A (zh) | 2010-04-01 | 2015-01-07 | 奇斯药制品公司 | 用于制备可吸入干粉所用的载体颗粒的方法 |
| UY33337A (es) | 2010-10-18 | 2011-10-31 | Respivert Ltd | DERIVADOS SUSTITUIDOS DE 1H-PIRAZOL[ 3,4-d]PIRIMIDINA COMO INHIBIDORES DE LAS FOSFOINOSITIDA 3-QUINASAS |
| MX357170B (es) | 2012-03-13 | 2018-06-27 | Respivert Ltd | Uso de sal metálica de ácido estárico o de estearil fumarato particulada para estabilizar una formulación farmacéutica. |
| ES2814336T3 (es) | 2012-04-13 | 2021-03-26 | Glaxosmithkline Ip Dev Ltd | Partículas de agregado |
| US10058530B2 (en) | 2012-10-25 | 2018-08-28 | The General Hospital Corporation | Combination therapies for the treatment of Alzheimer's disease and related disorders |
| CA3111941A1 (en) | 2012-10-25 | 2014-05-01 | The General Hospital Corporation | Combination therapies for the treatment of alzheimer's disease and related disorders |
| WO2014106727A1 (en) * | 2013-01-03 | 2014-07-10 | Vectura Limited | Inhaler and formulation |
| GB201305825D0 (en) * | 2013-03-28 | 2013-05-15 | Vectura Ltd | New use |
| US10525005B2 (en) | 2013-05-23 | 2020-01-07 | The General Hospital Corporation | Cromolyn compositions and methods thereof |
| CN106102737B (zh) | 2013-10-22 | 2019-06-14 | 综合医院公司 | 色甘酸衍生物以及成像和治疗的相关方法 |
| CA3033079A1 (en) | 2016-08-31 | 2018-03-08 | The General Hospital Corporation | Macrophages/microglia in neuro-inflammation associated with neurodegenerative diseases |
| JP7202376B2 (ja) | 2017-07-20 | 2023-01-11 | エーゼットセラピーズ， インコーポレイテッド | クロモリンナトリウムおよびイブプロフェンの粉末製剤 |
| CN115919780A (zh) * | 2017-09-22 | 2023-04-07 | 维克图拉公司 | 含有硬脂酸镁的干粉组合物 |
| CN113038944A (zh) | 2018-07-02 | 2021-06-25 | 通用医疗公司 | 色甘酸钠和α-乳糖的粉末化制剂 |
| WO2023224577A1 (en) * | 2022-05-18 | 2023-11-23 | Arven Ilac Sanayi Ve Ticaret Anonim Sirketi | Inhalation compositions comprising micronized human insulin |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1131059B1 (de) | 1998-11-13 | 2003-03-05 | Jago Research Ag | Trockenpulver zur inhalation |
| PT1158958E (pt) | 1999-03-05 | 2007-08-13 | Chiesi Farma Spa | ''composições farmacêuticas em pó, melhoradas, para inalação'' |
| PE20011227A1 (es) | 2000-04-17 | 2002-01-07 | Chiesi Farma Spa | Formulaciones farmaceuticas para inhaladores de polvo seco en la forma de aglomerados duros |
| DE60239639D1 (de) | 2002-07-31 | 2011-05-12 | Chiesi Farma Spa | Pulverinhalator |
| US20060147389A1 (en) * | 2004-04-14 | 2006-07-06 | Vectura Ltd. | Devices and pharmaceutical compositions for enhancing dosing efficiency |
| JP2009513529A (ja) | 2003-07-11 | 2009-04-02 | グラクソ グループ リミテッド | ステアリン酸マグネシウムを含む医薬製剤 |
| GB0613161D0 (en) * | 2006-06-30 | 2006-08-09 | Novartis Ag | Organic Compounds |
| GB0714134D0 (en) * | 2007-07-19 | 2007-08-29 | Norton Healthcare Ltd | Dry-powder medicament |
| US7590021B2 (en) | 2007-07-26 | 2009-09-15 | Qualcomm Incorporated | System and method to reduce dynamic RAM power consumption via the use of valid data indicators |
| EP2022783A1 (en) | 2007-08-08 | 2009-02-11 | CHIESI FARMACEUTICI S.p.A. | "Derivatives of 1-phenyl-2-pyridinyl alkyl alcohols as phosphodiesterase inhibitors" |
| EP2154136A1 (en) * | 2008-08-08 | 2010-02-17 | CHIESI FARMACEUTICI S.p.A. | Quinuclidine carbonate derivatives and medicinal compositions thereof |
-
2011
- 2011-09-16 KR KR1020177027944A patent/KR101886987B1/ko active IP Right Grant
- 2011-09-16 EP EP11767661.9A patent/EP2621494B1/en active Active
- 2011-09-16 ES ES11767661T patent/ES2704688T3/es active Active
- 2011-09-16 CA CA2813096A patent/CA2813096C/en active Active
- 2011-09-16 CN CN201180047864.3A patent/CN103298470B/zh active Active
- 2011-09-16 KR KR1020137007256A patent/KR20140005150A/ko not_active Application Discontinuation
- 2011-09-16 TR TR2019/01644T patent/TR201901644T4/tr unknown
- 2011-09-16 RU RU2013113965/15A patent/RU2580890C2/ru active
- 2011-09-16 BR BR112013007022-6A patent/BR112013007022B1/pt active IP Right Grant
- 2011-09-16 WO PCT/EP2011/066062 patent/WO2012041717A1/en active Application Filing
- 2011-09-16 PL PL11767661T patent/PL2621494T3/pl unknown
- 2011-09-22 US US13/239,903 patent/US20120082727A1/en not_active Abandoned
- 2011-09-29 AR ARP110103586A patent/AR083208A1/es not_active Application Discontinuation
-
2014
- 2014-01-29 HK HK14100919.2A patent/HK1187822A1/xx unknown
-
2015
- 2015-07-17 US US14/801,882 patent/US20150320691A1/en not_active Abandoned
-
2018
- 2018-01-12 US US15/869,162 patent/US20180133161A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US20180133161A1 (en) | 2018-05-17 |
| RU2580890C2 (ru) | 2016-04-10 |
| HK1187822A1 (en) | 2014-04-17 |
| RU2013113965A (ru) | 2014-10-10 |
| KR20170118231A (ko) | 2017-10-24 |
| WO2012041717A1 (en) | 2012-04-05 |
| AR083208A1 (es) | 2013-02-06 |
| EP2621494A1 (en) | 2013-08-07 |
| KR20140005150A (ko) | 2014-01-14 |
| US20150320691A1 (en) | 2015-11-12 |
| TR201901644T4 (tr) | 2019-02-21 |
| CN103298470A (zh) | 2013-09-11 |
| US20120082727A1 (en) | 2012-04-05 |
| CA2813096C (en) | 2019-10-29 |
| KR101886987B1 (ko) | 2018-08-08 |
| ES2704688T3 (es) | 2019-03-19 |
| EP2621494B1 (en) | 2018-11-07 |
| CN103298470B (zh) | 2015-06-17 |
| CA2813096A1 (en) | 2012-04-05 |
| BR112013007022B1 (pt) | 2019-10-15 |
| PL2621494T3 (pl) | 2019-04-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B07E | Notice of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] |
Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI |
|
| B06T | Formal requirements before examination [chapter 6.20 patent gazette] | ||
| B09A | Decision: intention to grant [chapter 9.1 patent gazette] | ||
| B16A | Patent or certificate of addition of invention granted |
Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 16/09/2011, OBSERVADAS AS CONDICOES LEGAIS. (CO) 20 (VINTE) ANOS CONTADOS A PARTIR DE 16/09/2011, OBSERVADAS AS CONDICOES LEGAIS |