BR112012031920A2 - tratamento de coagulopatias com hiperfibrinólise. - Google Patents

tratamento de coagulopatias com hiperfibrinólise.

Info

Publication number
BR112012031920A2
BR112012031920A2 BR112012031920A BR112012031920A BR112012031920A2 BR 112012031920 A2 BR112012031920 A2 BR 112012031920A2 BR 112012031920 A BR112012031920 A BR 112012031920A BR 112012031920 A BR112012031920 A BR 112012031920A BR 112012031920 A2 BR112012031920 A2 BR 112012031920A2
Authority
BR
Brazil
Prior art keywords
hyperfibrinolysis
coagulopathies
treatment
thrombomodulin analogs
hyperibrinolysis
Prior art date
Application number
BR112012031920A
Other languages
English (en)
Portuguese (pt)
Inventor
Herbert Foley Jonathan
Petersen Karl-Uwe
Ernest Nesheim Michael (Falecido)
Original Assignee
Paion Deutschland Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/EP2010/003541 external-priority patent/WO2010142461A2/en
Application filed by Paion Deutschland Gmbh filed Critical Paion Deutschland Gmbh
Publication of BR112012031920A2 publication Critical patent/BR112012031920A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C07K14/7455—Thrombomodulin

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Hematology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
BR112012031920A 2010-06-14 2010-12-15 tratamento de coagulopatias com hiperfibrinólise. BR112012031920A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PCT/EP2010/003541 WO2010142461A2 (en) 2009-06-12 2010-06-14 Treatment of coagulopathy with hyperfibrinolysis
PCT/EP2010/007632 WO2011157283A1 (en) 2010-06-14 2010-12-15 Treatment of coagulopathy with hyperfibrinolysis

Publications (1)

Publication Number Publication Date
BR112012031920A2 true BR112012031920A2 (pt) 2017-05-16

Family

ID=43857859

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112012031920A BR112012031920A2 (pt) 2010-06-14 2010-12-15 tratamento de coagulopatias com hiperfibrinólise.

Country Status (6)

Country Link
JP (1) JP2013531651A (enExample)
CN (1) CN103037893A (enExample)
AU (1) AU2010355558A1 (enExample)
BR (1) BR112012031920A2 (enExample)
CA (1) CA2802072A1 (enExample)
WO (1) WO2011157283A1 (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103298937B (zh) 2010-11-17 2016-05-25 中外制药株式会社 具有代替凝血因子viii的功能的功能的多特异性抗原结合分子
TW201625299A (zh) * 2014-06-20 2016-07-16 Chugai Pharmaceutical Co Ltd 用於因第ｖｉｉｉ凝血因子及／或活化的第ｖｉｉｉ凝血因子的活性降低或欠缺而發病及／或進展的疾病之預防及／或治療之醫藥組成物
MX2018012648A (es) 2016-04-28 2019-01-30 Chugai Pharmaceutical Co Ltd Preparaciones que contienen anticuerpos.
ES3000618T3 (en) 2016-09-06 2025-03-03 Chugai Pharmaceutical Co Ltd Methods of using a bispecific antibody that recognizes coagulation factor ix and/or activated coagulation factor ix and coagulation factor x and/or activated coagulation factor x
CN107083357B (zh) * 2017-06-16 2021-04-02 四川农业大学 一种诱导培养骨髓间充质干细胞的方法
JP2019031486A (ja) * 2017-08-04 2019-02-28 公立大学法人福島県立医科大学 新規ポリペプチド及びその用途
CN107677834B (zh) * 2017-09-25 2019-07-09 辽宁迈迪生物科技股份有限公司 TAFIa含量的检测方法、用于检测TAFIa含量的试剂盒及二者的应用
SG11202003833TA (en) 2017-11-01 2020-05-28 Chugai Pharmaceutical Co Ltd Antibody variant and isoform with lowered biological activity
CN111961137B (zh) * 2020-08-27 2023-09-05 南开大学 仿生内皮细胞功能的融合蛋白及其应用

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3856335T2 (de) 1987-01-08 2000-01-27 Asahi Kasei Kogyo K.K., Osaka Peptid zur beschleunigung der wirkung des proteins-c mit thrombin
US5256770A (en) 1990-04-09 1993-10-26 Schering Ag Oxidation resistant thrombomodulin analogs
EP0544826B1 (en) 1990-08-15 2002-01-02 Paion GmbH Superior thrombomodulin analogs for pharmaceutical use
PT641215E (pt) 1992-02-05 2004-09-30 Paion Gmbh Analogos de trombomodulina resistentes a proteases
WO1993025675A1 (en) * 1992-06-10 1993-12-23 Schering Aktiengesellschaft Mutants of the epidermal growth factor domains of human thrombomodulin
US6808927B2 (en) 2001-04-04 2004-10-26 American Diagnostica, Inc. Method of preparation of stabilized thrombin-activatable fibrinolysis inhibitor (TAFI) and methods of use thereof
CA2671863C (en) * 2006-12-12 2015-07-21 Eli Lilly And Company Method of treating acute renal failure with thrombomodulin variants
EA201270009A1 (ru) * 2009-06-12 2012-07-30 Пайон Дойчланд Гмбх Лечение коагулопатии с гиперфибринолизом

Also Published As

Publication number Publication date
JP2013531651A (ja) 2013-08-08
CA2802072A1 (en) 2011-12-22
CN103037893A (zh) 2013-04-10
AU2010355558A1 (en) 2013-01-24
WO2011157283A1 (en) 2011-12-22

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Legal Events

Date Code Title Description
B08F Application fees: application dismissed [chapter 8.6 patent gazette]
B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]
B350 Update of information on the portal [chapter 15.35 patent gazette]