BR112012009245A2 - ''anticorpo,polinucleotídeo,celula hospedeira,método para fabricar um anticorpo,imunoconjugado,formulação farmacêutica e uso do anticorpo'' - Google Patents
''anticorpo,polinucleotídeo,celula hospedeira,método para fabricar um anticorpo,imunoconjugado,formulação farmacêutica e uso do anticorpo''Info
- Publication number
- BR112012009245A2 BR112012009245A2 BR112012009245A BR112012009245A BR112012009245A2 BR 112012009245 A2 BR112012009245 A2 BR 112012009245A2 BR 112012009245 A BR112012009245 A BR 112012009245A BR 112012009245 A BR112012009245 A BR 112012009245A BR 112012009245 A2 BR112012009245 A2 BR 112012009245A2
- Authority
- BR
- Brazil
- Prior art keywords
- antibody
- immunoconjugate
- polynucleotide
- making
- host cell
- Prior art date
Links
- 229940127121 immunoconjugate Drugs 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 102000040430 polynucleotide Human genes 0.000 title 1
- 108091033319 polynucleotide Proteins 0.000 title 1
- 239000002157 polynucleotide Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/55—Fab or Fab'
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Immunology (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Oncology (AREA)
- Transplantation (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Crystals, And After-Treatments Of Crystals (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US25297309P | 2009-10-19 | 2009-10-19 | |
| PCT/US2010/053054 WO2011049868A1 (en) | 2009-10-19 | 2010-10-18 | Modulators of hepatocyte growth factor activator |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR112012009245A2 true BR112012009245A2 (pt) | 2019-09-24 |
Family
ID=43216178
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112012009245A BR112012009245A2 (pt) | 2009-10-19 | 2010-10-18 | ''anticorpo,polinucleotídeo,celula hospedeira,método para fabricar um anticorpo,imunoconjugado,formulação farmacêutica e uso do anticorpo'' |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US8759491B2 (enExample) |
| EP (1) | EP2491058A1 (enExample) |
| JP (1) | JP5889794B2 (enExample) |
| KR (1) | KR20120106940A (enExample) |
| CN (1) | CN102791739B (enExample) |
| AR (1) | AR078667A1 (enExample) |
| BR (1) | BR112012009245A2 (enExample) |
| CA (1) | CA2771817A1 (enExample) |
| MX (1) | MX2012002013A (enExample) |
| RU (1) | RU2012120693A (enExample) |
| TW (1) | TW201119677A (enExample) |
| WO (1) | WO2011049868A1 (enExample) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20110206704A1 (en) * | 2009-10-19 | 2011-08-25 | Genentech, Inc. | Methods and compositions for modulating hepatocyte growth factor activator |
| US11547743B2 (en) | 2014-04-28 | 2023-01-10 | Eisai R&D Management Co., Ltd. | Lyophilized formulation of HGF |
| HUE055414T2 (hu) | 2016-03-17 | 2021-11-29 | Eisai R&D Man Co Ltd | Eljárás aktivált hepatocita növekedési faktor (HGF) elõállítására |
| EP3492105A4 (en) | 2016-07-26 | 2020-02-26 | Nihon University | THERAPEUTIC AGENT FOR PERIODONTITIS. |
| WO2023142096A1 (en) * | 2022-01-30 | 2023-08-03 | Westlake University | Composition and method for preventing and/or treating clostridioides difficile infections caused by clade 2 strains |
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| JPS5566585A (en) | 1978-11-14 | 1980-05-20 | Takeda Chem Ind Ltd | Novel maytansinoid compound and its preparation |
| US4256746A (en) * | 1978-11-14 | 1981-03-17 | Takeda Chemical Industries | Dechloromaytansinoids, their pharmaceutical compositions and method of use |
| JPS55102583A (en) * | 1979-01-31 | 1980-08-05 | Takeda Chem Ind Ltd | 20-acyloxy-20-demethylmaytansinoid compound |
| JPS55162791A (en) * | 1979-06-05 | 1980-12-18 | Takeda Chem Ind Ltd | Antibiotic c-15003pnd and its preparation |
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| JPS55164686A (en) | 1979-06-11 | 1980-12-22 | Takeda Chem Ind Ltd | Novel maytansinoid compound and its preparation |
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| JPS5645483A (en) * | 1979-09-19 | 1981-04-25 | Takeda Chem Ind Ltd | C-15003phm and its preparation |
| JPS5645485A (en) * | 1979-09-21 | 1981-04-25 | Takeda Chem Ind Ltd | Production of c-15003pnd |
| EP0028683A1 (en) | 1979-09-21 | 1981-05-20 | Takeda Chemical Industries, Ltd. | Antibiotic C-15003 PHO and production thereof |
| WO1982001188A1 (en) | 1980-10-08 | 1982-04-15 | Takeda Chemical Industries Ltd | 4,5-deoxymaytansinoide compounds and process for preparing same |
| US4450254A (en) * | 1980-11-03 | 1984-05-22 | Standard Oil Company | Impact improvement of high nitrile resins |
| US4419446A (en) | 1980-12-31 | 1983-12-06 | The United States Of America As Represented By The Department Of Health And Human Services | Recombinant DNA process utilizing a papilloma virus DNA as a vector |
| US4313946A (en) | 1981-01-27 | 1982-02-02 | The United States Of America As Represented By The Secretary Of Agriculture | Chemotherapeutically active maytansinoids from Trewia nudiflora |
| US4315929A (en) | 1981-01-27 | 1982-02-16 | The United States Of America As Represented By The Secretary Of Agriculture | Method of controlling the European corn borer with trewiasine |
| JPS57192389A (en) | 1981-05-20 | 1982-11-26 | Takeda Chem Ind Ltd | Novel maytansinoid |
| US4601978A (en) | 1982-11-24 | 1986-07-22 | The Regents Of The University Of California | Mammalian metallothionein promoter system |
| US4560655A (en) | 1982-12-16 | 1985-12-24 | Immunex Corporation | Serum-free cell culture medium and process for making same |
| US4657866A (en) | 1982-12-21 | 1987-04-14 | Sudhir Kumar | Serum-free, synthetic, completely chemically defined tissue culture media |
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| AU2005294146B2 (en) * | 2004-10-04 | 2011-09-15 | Genentech, Inc. | Modulators of hepatocyte growth factor activator |
| US7737115B2 (en) * | 2005-04-15 | 2010-06-15 | Genetech, Inc. | HGF beta chain variants |
-
2010
- 2010-10-18 JP JP2012535264A patent/JP5889794B2/ja not_active Expired - Fee Related
- 2010-10-18 EP EP10768167A patent/EP2491058A1/en not_active Ceased
- 2010-10-18 WO PCT/US2010/053054 patent/WO2011049868A1/en not_active Ceased
- 2010-10-18 AR ARP100103794A patent/AR078667A1/es unknown
- 2010-10-18 CN CN201080055074.5A patent/CN102791739B/zh not_active Expired - Fee Related
- 2010-10-18 TW TW099135474A patent/TW201119677A/zh unknown
- 2010-10-18 MX MX2012002013A patent/MX2012002013A/es active IP Right Grant
- 2010-10-18 BR BR112012009245A patent/BR112012009245A2/pt not_active IP Right Cessation
- 2010-10-18 RU RU2012120693/10A patent/RU2012120693A/ru not_active Application Discontinuation
- 2010-10-18 KR KR1020127009911A patent/KR20120106940A/ko not_active Ceased
- 2010-10-18 US US12/906,473 patent/US8759491B2/en not_active Expired - Fee Related
- 2010-10-18 CA CA2771817A patent/CA2771817A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| CN102791739B (zh) | 2014-10-15 |
| RU2012120693A (ru) | 2013-12-20 |
| MX2012002013A (es) | 2012-03-16 |
| WO2011049868A1 (en) | 2011-04-28 |
| JP2013507962A (ja) | 2013-03-07 |
| EP2491058A1 (en) | 2012-08-29 |
| HK1178180A1 (en) | 2013-09-06 |
| US20110091477A1 (en) | 2011-04-21 |
| CN102791739A (zh) | 2012-11-21 |
| CA2771817A1 (en) | 2011-04-28 |
| US8759491B2 (en) | 2014-06-24 |
| TW201119677A (en) | 2011-06-16 |
| KR20120106940A (ko) | 2012-09-27 |
| JP5889794B2 (ja) | 2016-03-22 |
| AR078667A1 (es) | 2011-11-23 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] | ||
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2543 DE 01-10-2019 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013. |