BR112012007067A2 - montagem de acionamento, haste de pistão, dispositivo de distribuição de fármaco e uso de uma mola - Google Patents

montagem de acionamento, haste de pistão, dispositivo de distribuição de fármaco e uso de uma mola

Info

Publication number
BR112012007067A2
BR112012007067A2 BR112012007067A BR112012007067A BR112012007067A2 BR 112012007067 A2 BR112012007067 A2 BR 112012007067A2 BR 112012007067 A BR112012007067 A BR 112012007067A BR 112012007067 A BR112012007067 A BR 112012007067A BR 112012007067 A2 BR112012007067 A2 BR 112012007067A2
Authority
BR
Brazil
Prior art keywords
piston rod
interlock
drive assembly
drive
operable
Prior art date
Application number
BR112012007067A
Other languages
English (en)
Inventor
Catherine Anne Macdonald
Christopher Jones
Garen Kouyoumjian
Robert Veasey
Simon Lewis Bilton
Original Assignee
Sanofi Aventis Deutschland
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Aventis Deutschland filed Critical Sanofi Aventis Deutschland
Publication of BR112012007067A2 publication Critical patent/BR112012007067A2/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/31576—Constructional features or modes of drive mechanisms for piston rods
    • A61M5/31578—Constructional features or modes of drive mechanisms for piston rods based on axial translation, i.e. components directly operatively associated and axially moved with plunger rod
    • A61M5/3158—Constructional features or modes of drive mechanisms for piston rods based on axial translation, i.e. components directly operatively associated and axially moved with plunger rod performed by axially moving actuator operated by user, e.g. an injection button
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533—Dosing mechanisms, i.e. setting a dose
    • A61M5/31535—Means improving security or handling thereof, e.g. blocking means, means preventing insufficient dosing, means allowing correction of overset dose
    • A61M5/31543—Means improving security or handling thereof, e.g. blocking means, means preventing insufficient dosing, means allowing correction of overset dose piston rod reset means, i.e. means for causing or facilitating retraction of piston rod to its starting position during cartridge change
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533—Dosing mechanisms, i.e. setting a dose
    • A61M5/31545—Setting modes for dosing
    • A61M5/31548—Mechanically operated dose setting member
    • A61M5/31555—Mechanically operated dose setting member by purely axial movement of dose setting member, e.g. during setting or filling of a syringe
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
    • A61M2005/2403—Ampoule inserted into the ampoule holder
    • A61M2005/2407—Ampoule inserted into the ampoule holder from the rear
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
    • A61M2005/2477—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic comprising means to reduce play of ampoule within ampoule holder, e.g. springs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M2005/3125—Details specific display means, e.g. to indicate dose setting
    • A61M2005/3126—Specific display means related to dosing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533—Dosing mechanisms, i.e. setting a dose
    • A61M5/31535—Means improving security or handling thereof, e.g. blocking means, means preventing insufficient dosing, means allowing correction of overset dose
    • A61M5/31541—Means preventing setting of a dose beyond the amount remaining in the cartridge
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533—Dosing mechanisms, i.e. setting a dose
    • A61M5/31545—Setting modes for dosing
    • A61M5/31548—Mechanically operated dose setting member
    • A61M5/31556—Accuracy improving means

Landscapes

  • Health & Medical Sciences (AREA)
  • Vascular Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Detergent Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

montagem de acionamento, haste de pistão, dispositivo de distribuiçã de fármaco e uso de mola. a presente invenção refere-se a uma montagem de acionamento reajustável para um dispositivo de distribuição de fármaco. a montagem de acionamento reajustável pode compreender um alojamento (10a, 10b, 10c) que tem uma extremidade proximal (100p) e uma extremidade distal (100d), uma haste de pistão (20) que é giratória em relação ao alojamento (10a, 10b 10c) e que é axialmente deslocável em relação ao alojamento (10a, 10b, 10c) entre uma posição inicial proximal e uma posição final distal, um membro de acionamento (30) para deslocar distalmente a haste de pistão (20) em direção á posição final ao dispensar uma dose, e um membro limitador (50). a montagem de acionamento (30) seja operável para interagir com a haste de pistão (20) para formar um primeiro intertravamento destratável, sendo que o primeiro intertravamento é operável para bloquear o movimento proximal de haste de pistão (20) em relação ao membro de acionamento (30). a montagem de acionamento pode ser configurada de modo que o membro limitador (50) seja operável para interagir com a haste de pistão (20) para formar um segundo intertravamento destravável, sendo que o segundo intertravamento é operável para bloquear o movimento proximal da haste de pistão (20) para formar um segundo intertravamento destravável, sendo que o segundo intertravamento é operável para bloquear o movimento proximal da haste de pistão (20) em relação ao alojamento (10a, 10b, 10c). a montagem de acionamento pode ser configurada de modo que, quando a montagem de acionamento pode ser configurada de modo que, quando a montagem de acionamento se encontrar em um modo de acionamento, os primeiro e segundo intertravamentos sejam travados de modo que o movimento proximal da haste de pistão (20) a partir da posição final até a posição inicial seja evitado pelo primeiro intertravamento e pelo segundo intertravamento. a montagem de acionamento pode ser configurada de modo que, para comutar a montagem de acionamento a partir do modo de acionamento para um modo de reajuste, a haste de pistão (20) seja giratória em relação ao membro de acionamento (30) para destravar o primeiro intertravamento e o membro limitador (50) e a haste de pistão (20) sejam giratórios em relação um ao outro para destravar o segundo intertravamento. a montagem de acionamento pode ser configurada de modo que, quando a montagem de acionamento se encontrar no modo de reajuste, o primeiro intertravamento e o segundo intertravamento sejam destravados de modo que o modo que o movimento proximal da haste de pistão (20) até a posição inicial seja permitido. ademais, são proporcionados um dispositivo de distribuição de fármaco e o uso de uma mola.
BR112012007067A 2009-09-30 2010-09-29 montagem de acionamento, haste de pistão, dispositivo de distribuição de fármaco e uso de uma mola BR112012007067A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP09171748 2009-09-30
PCT/EP2010/064407 WO2011039216A2 (en) 2009-09-30 2010-09-29 Drive assembly, piston rod, drug delivery device, and use of a spring

Publications (1)

Publication Number Publication Date
BR112012007067A2 true BR112012007067A2 (pt) 2016-04-19

Family

ID=42025052

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112012007067A BR112012007067A2 (pt) 2009-09-30 2010-09-29 montagem de acionamento, haste de pistão, dispositivo de distribuição de fármaco e uso de uma mola

Country Status (19)

Country Link
US (1) US9375535B2 (pt)
EP (2) EP2574358B1 (pt)
JP (1) JP5675822B2 (pt)
KR (1) KR20120091153A (pt)
CN (1) CN102639171B (pt)
AR (1) AR078458A1 (pt)
AU (1) AU2010303060B2 (pt)
BR (1) BR112012007067A2 (pt)
CA (1) CA2773017A1 (pt)
DK (2) DK2574358T3 (pt)
HK (2) HK1184398A1 (pt)
IL (1) IL218833A (pt)
MX (1) MX2012003812A (pt)
MY (1) MY154057A (pt)
NZ (1) NZ599026A (pt)
RU (1) RU2552669C2 (pt)
TW (1) TW201121601A (pt)
WO (1) WO2011039216A2 (pt)
ZA (1) ZA201201356B (pt)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2003209095A1 (en) 2002-02-11 2003-09-04 Antares Pharma, Inc. Intradermal injector
DK1850892T4 (da) 2005-01-24 2023-06-06 Antares Pharma Inc Forfyldt nål-assisteret sprøjtejetinjektor
US9144648B2 (en) 2006-05-03 2015-09-29 Antares Pharma, Inc. Injector with adjustable dosing
US8251947B2 (en) 2006-05-03 2012-08-28 Antares Pharma, Inc. Two-stage reconstituting injector
EP2990067B1 (en) 2008-03-10 2019-09-04 Antares Pharma, Inc. Injector safety device
EP2318075B1 (en) 2008-08-05 2019-05-22 Antares Pharma, Inc. Multiple dosage injector
EP2468344B1 (en) * 2008-10-13 2013-08-28 Sanofi-Aventis Deutschland GmbH Drug delivery device and method of manufacturing a drug delivery device
WO2010108116A1 (en) 2009-03-20 2010-09-23 Antares Pharma, Inc. Hazardous agent injection system
US8496619B2 (en) 2011-07-15 2013-07-30 Antares Pharma, Inc. Injection device with cammed ram assembly
US9220660B2 (en) 2011-07-15 2015-12-29 Antares Pharma, Inc. Liquid-transfer adapter beveled spike
EP2766072B1 (en) * 2011-10-14 2018-11-28 Sanofi-Aventis Deutschland GmbH Assembly for a drug delivery device
ES2741484T3 (es) * 2012-02-03 2020-02-11 Injectec Ltd Armazón de jeringa
AU2013224349A1 (en) 2012-02-24 2014-08-21 Novo Nordisk A/S Drug delivery device with front loading feature
DK2822618T3 (da) 2012-03-06 2024-01-22 Antares Pharma Inc Forfyldt nål med brudkraftfunktion
AU2013203784A1 (en) 2012-04-06 2013-10-24 Kaushik J. Dave Needle assisted jet injection administration of testosterone compositions
US9364611B2 (en) 2012-05-07 2016-06-14 Antares Pharma, Inc. Needle assisted jet injection device having reduced trigger force
JP2016507305A (ja) 2013-02-11 2016-03-10 アンタレス・ファーマ・インコーポレーテッド トリガ力を低減した針支援式ジェット注射装置
JP6360470B2 (ja) * 2013-03-08 2018-07-18 テルモ株式会社 液体投与具
EP2968792B1 (en) 2013-03-11 2019-05-15 Antares Pharma, Inc. Dosage injector with pinion system
WO2014165136A1 (en) 2013-03-12 2014-10-09 Antares Pharma, Inc. Constant volume prefilled syringes and kits thereof
CA2906245C (en) 2013-03-14 2019-04-30 Norton Healthcare Limited Dispensing mechanism for a medical device
US10117997B2 (en) * 2013-03-14 2018-11-06 Norton Healthcare Limited Dispensing mechanism for a medical device
GB2511806A (en) 2013-03-14 2014-09-17 Norton Healthcare Ltd Dispensing mechanism for a medical device
JP6307528B2 (ja) 2013-03-14 2018-04-04 ノートン・ヘルスケア・リミテッド 医療器具のための投薬機構
EP2986334B1 (en) * 2013-04-18 2019-03-20 Novo Nordisk A/S Fixation of a torsion spring
TR201903611T4 (tr) * 2013-05-16 2019-04-22 Sanofi Aventis Deutschland Bir ilaç dağıtım cihazına yönelik düzenek ve ilaç dağıtım cihazı.
WO2016055438A1 (en) * 2014-10-09 2016-04-14 Sanofi Drive mechanism of an injection device
US10441722B2 (en) * 2015-04-29 2019-10-15 Novo Nordisk A/S Drug delivery device with spring mechanism
WO2018060310A1 (en) 2016-09-29 2018-04-05 Ascendis Pharma Bone Diseases A/S Dosage regimen for a controlled-release pth compound
EP3880274A1 (en) * 2018-11-13 2021-09-22 Credence Medsystems, Inc. System and method for microdose injection
EP3808393A1 (en) * 2019-10-15 2021-04-21 Ypsomed AG Cartridge fixation for a drug delivery device

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9007113D0 (en) * 1990-03-29 1990-05-30 Sams Bernard Dispensing device
JPH04256758A (ja) * 1991-02-07 1992-09-11 Terumo Corp 定量分与器
DK175491D0 (da) * 1991-10-18 1991-10-18 Novo Nordisk As Apparat
GB9219849D0 (en) * 1992-09-19 1992-10-28 Hypoguard Uk Ltd Device
TW245642B (pt) * 1992-09-29 1995-04-21 Alza Corp
SE9301494D0 (sv) * 1993-04-30 1993-04-30 Kabi Pharmacia Ab A device for dosing liquid preparation
DK1228777T3 (da) * 1994-05-30 2004-03-01 B D Medico S A R L Injektionsudstyr
US6663602B2 (en) * 2000-06-16 2003-12-16 Novo Nordisk A/S Injection device
WO2002017996A1 (en) 2000-08-29 2002-03-07 Novo Nordisk A/S Automatic injection device with torsion function for retraction of needle
JP4288156B2 (ja) 2001-07-16 2009-07-01 イーライ リリー アンド カンパニー 充填用に回転かつ注射用にプル・プッシュ形式の投薬装置
DE102004020374A1 (de) * 2004-04-23 2005-11-10 Tecpharma Licensing Ag Vorrichtung zur Verabreichung eines injizierbaren Produkts mit gesicherter Dosiereinrichtung
US7896850B2 (en) 2005-06-01 2011-03-01 Telefonaktiebolaget L M Ericsson (Publ) Device for delivering medicament
JP5044565B2 (ja) * 2006-10-18 2012-10-10 テルモ株式会社 医療器具
EP1923083A1 (en) 2006-11-17 2008-05-21 Sanofi-Aventis Deutschland GmbH Drive mechanisms for use in drug delivery devices
WO2009007305A1 (en) 2007-07-06 2009-01-15 Novo Nordisk A/S Automatic injection device
WO2010029043A1 (en) * 2008-09-09 2010-03-18 Shl Group Ab Medicament delivery device

Also Published As

Publication number Publication date
DK2482876T3 (da) 2014-01-13
IL218833A (en) 2014-11-30
NZ599026A (en) 2014-02-28
US9375535B2 (en) 2016-06-28
IL218833A0 (en) 2012-06-28
CA2773017A1 (en) 2011-04-07
EP2482876A2 (en) 2012-08-08
WO2011039216A2 (en) 2011-04-07
RU2552669C2 (ru) 2015-06-10
AR078458A1 (es) 2011-11-09
EP2574358B1 (en) 2014-11-26
JP5675822B2 (ja) 2015-02-25
KR20120091153A (ko) 2012-08-17
CN102639171B (zh) 2014-04-09
AU2010303060B2 (en) 2014-10-02
MY154057A (en) 2015-04-30
JP2013506454A (ja) 2013-02-28
US20130006193A1 (en) 2013-01-03
ZA201201356B (en) 2012-10-31
MX2012003812A (es) 2012-05-22
HK1169056A1 (en) 2013-01-18
WO2011039216A3 (en) 2011-06-03
RU2012117810A (ru) 2013-11-10
TW201121601A (en) 2011-07-01
AU2010303060A1 (en) 2012-04-19
DK2574358T3 (en) 2015-03-02
HK1184398A1 (en) 2014-01-24
EP2574358A1 (en) 2013-04-03
CN102639171A (zh) 2012-08-15
EP2482876B1 (en) 2013-09-25

Similar Documents

Publication Publication Date Title
BR112012007067A2 (pt) montagem de acionamento, haste de pistão, dispositivo de distribuição de fármaco e uso de uma mola
BR112013020670A2 (pt) injetor automático
BR112013020900A2 (pt) autoinjetor
BR112012007338A2 (pt) mecanismo acionador restaurável para um dispositivo de aplicação de fármaco
BR112012007310A2 (pt) mecanismo de acionamento para um dispositivo de entrega de fármaco e uso de um membro de reajuste para um mecanismo de acionamento
BR112013020907A2 (pt) autoinjetor
BR112012029642A2 (pt) dispositivo de administração de droga
BR112013020805A2 (pt) autoinjetor
NI200900087A (es) Mejoras en y relacionadas con mecanismo accionadores adecuados para usarse en dispositivos de descarga de fármacos
MY155197A (en) Drive mechanism for a medication delivery device and medication delivery device
BR112014012480A2 (pt) seringa de segurança
BR112012033616A2 (pt) dispositivo de segurança para uma seringa preenchida e dispositivo de injeção
BR112015023138A2 (pt) instrumento cirúrgico com múltiplos mecanismos de pinçamento
MY151554A (en) Medication delivery device
MY148822A (en) Medication delivery device
NZ602539A (en) Piston rod assembly for a drug delivery device
BR112012007608A2 (pt) mecanismo de acionamento para um dispositivo de distribuição de fármaco e uso de um elemento elástico para um mecanismo de acionamento
RU2014137435A (ru) Устройство для доставки лекарства с функцией загрузки картриджем с переднего своего конца
CL2009000018A1 (es) Analogo de la insulina con tiempo de accion plano y prolongado; procedimiento de preparación; uso para tratar diabetes mellitus; producto farmaceutico y formulacion que lo comprende; secuencia nucleotidica que lo codifica; vector; y célula hospedera.
WO2007073486A3 (en) Methods and compositions for delivering active agents with enhanced pharmacological properties
MX2013009167A (es) Auto-inyector.
BRPI0818687A2 (pt) composto espiro, o sal deste farmaceuticamente aceitavél ou o solvato deste, composição farmacêutica, medicamento agonista de gpr40, agente promotor da secreção de insulina ou um agente hipoglicêmico, uso do composto espíro, o sal deste farmaceuticamente aceitavél ou o solvato deste, e, métodos para a ativação de gpr40, para promover secreção de insulina ou diminuir o nível de glicose sanguínea, e para tratar ou prevenir uma doença.
EA200800704A1 (ru) Одноразовый безопасный шприц со втягивающейся иглой
WO2012117379A3 (fr) Inserteur de canule
BR112014032695A2 (pt) formulações estáveis para injeção parenteral de fármacos de pequenas moléculas

Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 6A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2385 DE 20-09-2016 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.