BR102021017465A2 - Método para produção de tecido conjuntivo colágeno preservado, tecido conjuntivo colágeno, seus usos e kit para implante em tecido - Google Patents

Método para produção de tecido conjuntivo colágeno preservado, tecido conjuntivo colágeno, seus usos e kit para implante em tecido Download PDF

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Publication number
BR102021017465A2
BR102021017465A2 BR102021017465-0A BR102021017465A BR102021017465A2 BR 102021017465 A2 BR102021017465 A2 BR 102021017465A2 BR 102021017465 A BR102021017465 A BR 102021017465A BR 102021017465 A2 BR102021017465 A2 BR 102021017465A2
Authority
BR
Brazil
Prior art keywords
connective tissue
tissue
solution
collagen connective
production
Prior art date
Application number
BR102021017465-0A
Other languages
English (en)
Portuguese (pt)
Inventor
Ivan Sérgio Joviano Casagrande
Gustavo Padilha Junqueira De Souza
Original Assignee
Labcor Laboratórios Ltda.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Labcor Laboratórios Ltda. filed Critical Labcor Laboratórios Ltda.
Priority to BR102021017465-0A priority Critical patent/BR102021017465A2/pt
Priority to US18/688,672 priority patent/US20240373841A1/en
Priority to JP2024514372A priority patent/JP2024531568A/ja
Priority to PCT/BR2022/050348 priority patent/WO2023028681A1/pt
Priority to EP22862452.4A priority patent/EP4397299A4/en
Publication of BR102021017465A2 publication Critical patent/BR102021017465A2/pt
Priority to US19/059,370 priority patent/US20250185647A1/en

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3604Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00Preservation of bodies of humans or animals, or parts thereof
    • A01N1/10Preservation of living parts
    • A01N1/12Chemical aspects of preservation
    • A01N1/122Preservation or perfusion media
    • A01N1/124Disinfecting agents, e.g. antimicrobials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3641Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the site of application in the body
    • A61L27/3645Connective tissue
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3683Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
    • A61L27/3687Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment characterised by the use of chemical agents in the treatment, e.g. specific enzymes, detergents, capping agents, crosslinkers, anticalcification agents
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0652Cells of skeletal and connective tissues; Mesenchyme
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00Materials or treatment for tissue regeneration
    • A61L2430/02Materials or treatment for tissue regeneration for reconstruction of bones; weight-bearing implants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00Materials or treatment for tissue regeneration
    • A61L2430/12Materials or treatment for tissue regeneration for dental implants or prostheses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00Materials or treatment for tissue regeneration
    • A61L2430/34Materials or treatment for tissue regeneration for soft tissue reconstruction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14Macromolecular materials
    • A61L27/22Polypeptides or derivatives thereof, e.g. degradation products
    • A61L27/24Collagen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/60Materials for use in artificial skin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Wood Science & Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Transplantation (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Medicinal Chemistry (AREA)
  • Dermatology (AREA)
  • Botany (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Rheumatology (AREA)
  • General Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Environmental Sciences (AREA)
  • Dentistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Prostheses (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Materials For Medical Uses (AREA)
BR102021017465-0A 2021-09-02 2021-09-02 Método para produção de tecido conjuntivo colágeno preservado, tecido conjuntivo colágeno, seus usos e kit para implante em tecido BR102021017465A2 (pt)

Priority Applications (6)

Application Number Priority Date Filing Date Title
BR102021017465-0A BR102021017465A2 (pt) 2021-09-02 2021-09-02 Método para produção de tecido conjuntivo colágeno preservado, tecido conjuntivo colágeno, seus usos e kit para implante em tecido
US18/688,672 US20240373841A1 (en) 2021-09-02 2022-09-01 Method for producing preserved collagenous connective tissue, collagenous connective tissue, uses thereof and kit for implant in tissues
JP2024514372A JP2024531568A (ja) 2021-09-02 2022-09-01 保存されたコラーゲン結合組織を作製するための方法、コラーゲン結合組織、その使用及び組織インプラント用キット
PCT/BR2022/050348 WO2023028681A1 (pt) 2021-09-02 2022-09-01 Método para produção de tecido conjuntivo colágeno preservado, tecido conjuntivo colágeno, seus usos e kit para implante em tecido
EP22862452.4A EP4397299A4 (en) 2021-09-02 2022-09-01 METHOD FOR PRODUCING PRESERVED COLLAGEN CONNECTIVE TISSUE, COLLAGEN CONNECTIVE TISSUE, ITS USES AND KIT FOR A TISSUE IMPLANT
US19/059,370 US20250185647A1 (en) 2021-09-02 2025-02-21 Method for producing preserved collagenous connective tissue, collagenous connective tissue, uses thereof and kit for implant in tissues

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
BR102021017465-0A BR102021017465A2 (pt) 2021-09-02 2021-09-02 Método para produção de tecido conjuntivo colágeno preservado, tecido conjuntivo colágeno, seus usos e kit para implante em tecido

Publications (1)

Publication Number Publication Date
BR102021017465A2 true BR102021017465A2 (pt) 2023-03-14

Family

ID=85410629

Family Applications (1)

Application Number Title Priority Date Filing Date
BR102021017465-0A BR102021017465A2 (pt) 2021-09-02 2021-09-02 Método para produção de tecido conjuntivo colágeno preservado, tecido conjuntivo colágeno, seus usos e kit para implante em tecido

Country Status (5)

Country Link
US (1) US20240373841A1 (https=)
EP (1) EP4397299A4 (https=)
JP (1) JP2024531568A (https=)
BR (1) BR102021017465A2 (https=)
WO (1) WO2023028681A1 (https=)

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5746775A (en) * 1988-04-01 1998-05-05 The Board Of Regent6S Of The University Of Michigan Method of making calcification-resistant bioprosthetic tissue
US5476516A (en) * 1992-03-13 1995-12-19 Albert Einstein College Of Medicine Of Yeshiva University Anticalcification treatment for aldehyde-tanned biological tissue
US7008763B2 (en) * 2002-09-23 2006-03-07 Cheung David T Method to treat collagenous connective tissue for implant remodeled by host cells into living tissue
EP1796693A2 (en) * 2004-08-26 2007-06-20 Chandrashekhar P. Pathak Implantable tissue compositions and method
WO2006066327A1 (en) 2004-12-24 2006-06-29 Celxcel Pty Ltd An implantable biomaterial and a method of producing same
CN106190949B (zh) * 2015-05-08 2020-04-10 上海微创心通医疗科技有限公司 一种干态动物源性胶原纤维组织材料及其制备方法和生物假体
JP7174712B2 (ja) * 2017-04-13 2022-11-17 オーバスネイチ・メディカル・プライベート・リミテッド ポリドーパミンおよび抗体でコーティングされた医療機器
CN109010927A (zh) * 2018-08-07 2018-12-18 中国人民解放军第二军医大学 一种可缓释生物活性因子的脱细胞牛心包基质的制备方法

Also Published As

Publication number Publication date
JP2024531568A (ja) 2024-08-29
EP4397299A1 (en) 2024-07-10
US20240373841A1 (en) 2024-11-14
WO2023028681A1 (pt) 2023-03-09
EP4397299A4 (en) 2025-09-10

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Legal Events

Date Code Title Description
B03A Publication of a patent application or of a certificate of addition of invention [chapter 3.1 patent gazette]
B11A Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing
B11Y Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette]