BR0315566A - Tetralinas e indanos substituìdos - Google Patents
Tetralinas e indanos substituìdosInfo
- Publication number
- BR0315566A BR0315566A BR0315566-8A BR0315566A BR0315566A BR 0315566 A BR0315566 A BR 0315566A BR 0315566 A BR0315566 A BR 0315566A BR 0315566 A BR0315566 A BR 0315566A
- Authority
- BR
- Brazil
- Prior art keywords
- indans
- substituted tetralines
- tetralines
- substituted
- tetralins
- Prior art date
Links
- 125000005329 tetralinyl group Chemical group C1(CCCC2=CC=CC=C12)* 0.000 title 1
- CXWXQJXEFPUFDZ-UHFFFAOYSA-N tetralin Chemical compound C1=CC=C2CCCCC2=C1 CXWXQJXEFPUFDZ-UHFFFAOYSA-N 0.000 abstract 2
- 102000023984 PPAR alpha Human genes 0.000 abstract 1
- 108010028924 PPAR alpha Proteins 0.000 abstract 1
- 206010012601 diabetes mellitus Diseases 0.000 abstract 1
- 125000003392 indanyl group Chemical class C1(CCC2=CC=CC=C12)* 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
- C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
- C07C323/52—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/325—Carbamic acids; Thiocarbamic acids; Anhydrides or salts thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
- C07C235/70—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups and doubly-bound oxygen atoms bound to the same carbon skeleton
- C07C235/84—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups and doubly-bound oxygen atoms bound to the same carbon skeleton with the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C275/28—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C275/32—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by singly-bound oxygen atoms
- C07C275/34—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by singly-bound oxygen atoms having nitrogen atoms of urea groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C333/00—Derivatives of thiocarbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C333/02—Monothiocarbamic acids; Derivatives thereof
- C07C333/08—Monothiocarbamic acids; Derivatives thereof having nitrogen atoms of thiocarbamic groups bound to carbon atoms of six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/04—Systems containing only non-condensed rings with a four-membered ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
- C07C2601/08—Systems containing only non-condensed rings with a five-membered ring the ring being saturated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/04—One of the condensed rings being a six-membered aromatic ring
- C07C2602/08—One of the condensed rings being a six-membered aromatic ring the other ring being five-membered, e.g. indane
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/04—One of the condensed rings being a six-membered aromatic ring
- C07C2602/10—One of the condensed rings being a six-membered aromatic ring the other ring being six-membered, e.g. tetraline
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Diabetes (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Cardiology (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Heart & Thoracic Surgery (AREA)
- Child & Adolescent Psychology (AREA)
- Epidemiology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US41992702P | 2002-10-21 | 2002-10-21 | |
US49575803P | 2003-08-15 | 2003-08-15 | |
PCT/US2003/033088 WO2004037777A1 (en) | 2002-10-21 | 2003-10-17 | Treating syndrome x with substituted tetralins and indanes |
Publications (1)
Publication Number | Publication Date |
---|---|
BR0315566A true BR0315566A (pt) | 2005-08-23 |
Family
ID=32179770
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR0315566-8A BR0315566A (pt) | 2002-10-21 | 2003-10-17 | Tetralinas e indanos substituìdos |
Country Status (17)
Country | Link |
---|---|
US (2) | US20040162352A1 (pt) |
EP (1) | EP1556344A1 (pt) |
JP (1) | JP2006503915A (pt) |
KR (1) | KR20050067419A (pt) |
AU (1) | AU2003279981A1 (pt) |
BR (1) | BR0315566A (pt) |
CA (1) | CA2503405A1 (pt) |
CO (1) | CO5690541A2 (pt) |
EA (1) | EA200500517A1 (pt) |
HR (1) | HRP20050337A2 (pt) |
MX (1) | MXPA05004296A (pt) |
NO (1) | NO20052277L (pt) |
NZ (1) | NZ539432A (pt) |
PL (1) | PL376470A1 (pt) |
RS (1) | RS20050319A (pt) |
TW (1) | TW200412935A (pt) |
WO (1) | WO2004037777A1 (pt) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BR0315596A (pt) * | 2002-10-21 | 2005-09-06 | Janssen Pharmaceutica Nv | Tetralinas e indanos substituìdos |
CN100354259C (zh) * | 2002-10-21 | 2007-12-12 | 詹森药业有限公司 | 取代的四氢化萘和茚满及其用途 |
KR20060060047A (ko) | 2003-10-01 | 2006-06-02 | 더 프록터 앤드 갬블 캄파니 | 멜라닌 농축 호르몬 길항제 |
AR048931A1 (es) * | 2004-04-21 | 2006-06-14 | Janssen Pharmaceutica Nv | Proceso para la preparacion de derivados de tetralina sustituida e indano sustituido y preparacion de intermediarios de sintesis |
US7550467B2 (en) * | 2004-10-12 | 2009-06-23 | Schering Corporation | Bicyclic compounds as selective melanin concentrating hormone receptor antagonists for the treatment of obesity and related disorders |
US20060263450A1 (en) * | 2005-05-17 | 2006-11-23 | Julius Oben | Method and composition for reducing body weight and improving control of body lipids |
FR2896160B1 (fr) * | 2006-01-13 | 2008-04-25 | Merck Sante Soc Par Actions Si | Combinaison de derives de triazine et d'agonistes du ppar alpha. |
US20100098792A1 (en) * | 2008-10-17 | 2010-04-22 | Gateway Health Alliances, Inc. | Methods and compositions using irvingia gabonensis to reduce weight, control obesity, effect adipogenesis, lower ppar-gamma, leptin, g3pdh and triglycerides levels and increase adiponectin levels |
US20100098793A1 (en) * | 2008-10-17 | 2010-04-22 | Gateway Health Alliances, Inc. | Irvingia gabonensis to treat and prevent metabolic syndrome and reduce total cholesterol, ldl cholesterol, blood glucose, c-reactive protein, and leptin levels and increasing adiponectin levels |
US20130203769A1 (en) * | 2012-02-08 | 2013-08-08 | University Of Cincinnati | Targeting Metabolic Adaptive Responses to Chemotherapy |
WO2016092547A1 (en) | 2014-12-09 | 2016-06-16 | Ezekiel Golan | Alcoholic beverage substitutes |
CN112500301B (zh) * | 2014-12-09 | 2024-02-13 | 以西结·戈兰 | 放纵行为调节剂 |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU632809B2 (en) * | 1989-05-25 | 1993-01-14 | Takeda Chemical Industries Ltd. | Benzocycloalkane benzopyran and benzothiopyran urea derivatives and production thereof |
GB9606805D0 (en) * | 1996-03-30 | 1996-06-05 | Glaxo Wellcome Inc | Medicaments |
GB9822473D0 (en) * | 1998-10-16 | 1998-12-09 | Glaxo Group Ltd | Chemical compounds |
EP1259494A4 (en) * | 2000-02-18 | 2004-09-15 | Merck & Co Inc | ARYLOXY ACETIC ACIDS FOR DIABETES AND LIPID DISEASES |
NZ525119A (en) * | 2000-10-05 | 2005-04-29 | Bayer Ag | Propionic acid derivatives |
JPWO2002044129A1 (ja) * | 2000-11-29 | 2004-04-02 | 杏林製薬株式会社 | 置換カルボン酸誘導体 |
JPWO2002046146A1 (ja) * | 2000-12-05 | 2004-04-08 | 杏林製薬株式会社 | 置換カルボン酸誘導体 |
US7091225B2 (en) * | 2000-12-20 | 2006-08-15 | Smithkline Beecham Corporation | Substituted oxazoles and thiazoles as hPPAR alpha agonists |
US6548538B2 (en) * | 2001-05-22 | 2003-04-15 | Bayer Aktiengesellschaft | Propionic acid derivatives |
WO2003007887A2 (en) * | 2001-07-20 | 2003-01-30 | Merck & Co., Inc. | Substituted imidazoles as cannabinoid receptor modulators |
UA82835C2 (en) * | 2001-12-03 | 2008-05-26 | Reddys Lab Ltd Dr | ?-aryl-?-oxysubstituted propionuc acid derivatives and pharmaceutical composition based thereon |
CN100354259C (zh) * | 2002-10-21 | 2007-12-12 | 詹森药业有限公司 | 取代的四氢化萘和茚满及其用途 |
BR0315596A (pt) * | 2002-10-21 | 2005-09-06 | Janssen Pharmaceutica Nv | Tetralinas e indanos substituìdos |
-
2003
- 2003-10-17 MX MXPA05004296A patent/MXPA05004296A/es not_active Application Discontinuation
- 2003-10-17 KR KR1020057006798A patent/KR20050067419A/ko not_active Application Discontinuation
- 2003-10-17 PL PL03376470A patent/PL376470A1/xx not_active Application Discontinuation
- 2003-10-17 CA CA002503405A patent/CA2503405A1/en not_active Abandoned
- 2003-10-17 NZ NZ539432A patent/NZ539432A/en not_active IP Right Cessation
- 2003-10-17 US US10/688,572 patent/US20040162352A1/en not_active Abandoned
- 2003-10-17 US US10/688,380 patent/US20040171680A1/en not_active Abandoned
- 2003-10-17 JP JP2005501628A patent/JP2006503915A/ja not_active Withdrawn
- 2003-10-17 AU AU2003279981A patent/AU2003279981A1/en not_active Abandoned
- 2003-10-17 WO PCT/US2003/033088 patent/WO2004037777A1/en active Application Filing
- 2003-10-17 BR BR0315566-8A patent/BR0315566A/pt not_active IP Right Cessation
- 2003-10-17 EA EA200500517A patent/EA200500517A1/ru unknown
- 2003-10-17 EP EP03773286A patent/EP1556344A1/en not_active Withdrawn
- 2003-10-17 RS YUP-2005/0319A patent/RS20050319A/sr unknown
- 2003-10-21 TW TW092129194A patent/TW200412935A/zh unknown
-
2005
- 2005-04-14 HR HR20050337A patent/HRP20050337A2/hr not_active Application Discontinuation
- 2005-05-10 NO NO20052277A patent/NO20052277L/no unknown
- 2005-05-20 CO CO05048979A patent/CO5690541A2/es active IP Right Grant
Also Published As
Publication number | Publication date |
---|---|
PL376470A1 (en) | 2005-12-27 |
CA2503405A1 (en) | 2004-05-06 |
AU2003279981A1 (en) | 2004-05-13 |
CO5690541A2 (es) | 2006-10-31 |
EA200500517A1 (ru) | 2005-10-27 |
MXPA05004296A (es) | 2005-11-23 |
RS20050319A (en) | 2007-09-21 |
US20040162352A1 (en) | 2004-08-19 |
JP2006503915A (ja) | 2006-02-02 |
NO20052277L (no) | 2005-06-29 |
TW200412935A (en) | 2004-08-01 |
KR20050067419A (ko) | 2005-07-01 |
EP1556344A1 (en) | 2005-07-27 |
WO2004037777A1 (en) | 2004-05-06 |
US20040171680A1 (en) | 2004-09-02 |
NZ539432A (en) | 2008-04-30 |
HRP20050337A2 (en) | 2005-12-31 |
NO20052277D0 (no) | 2005-05-10 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
BR0315566A (pt) | Tetralinas e indanos substituìdos | |
CY1110326T1 (el) | Υποκατασταθεισες τετραλινες και ινδανια και η χρηση τους | |
UY27884A1 (es) | Moduladores del receptor de glucocorticoides | |
BR0308653A (pt) | Cristais de derivado de benzeno de glicopiranosiloxibenzila | |
BRPI0417739A (pt) | (s)-2-n-propilamino-5-hidroxitetralina como um agonista d3 | |
BRPI0513709A (pt) | processo para a fotoativação e uso de um catalisador por um procedimento de dois estágios invertido | |
UY26130A1 (es) | Compuestos para tratar la obesidad | |
BR0113964A (pt) | Composição adesiva à base de dispersões de policloropreno | |
BRPI0414634A (pt) | agonistas de receptor b2, adrenérgico de etilamino amino-substituìdo | |
BR0305203A (pt) | Preparação de poliissocianatos contendo grupos uretdiona | |
ECSP088316A (es) | Moduladores sustituidos de 3-amido-tetrahidro-indazolil cannabinoide | |
BRPI0512395A (pt) | composto, composição farmacêutica, uso de um composto, e, métodos para o tratamento ou a profilaxia de condições ou distúrbios associadas(os) com a modulação de receptor de estrogênio seletiva, e para o tratamento ou a profilaxia relacionado(a) com condições ou distúrbios | |
BR0317229A (pt) | Composição e uso de agonista completo de alfa7nachr | |
ATE370941T1 (de) | Modulatoren des vitamin-d-rezeptors | |
CR20130055A (es) | Compuestos aromáticos apropiados para tratar trastornos que responden a la modulación del receptor de dopamina d3 | |
AR047553A1 (es) | La combinacion de un inhibidor de reabsorcion de serotonina y agomelatina | |
BR0315596A (pt) | Tetralinas e indanos substituìdos | |
ATE295717T1 (de) | Vitaminzusammensetzung für topische anwendungen | |
AR057362A1 (es) | Procedimientos para preparar un inhibidor de mek | |
BRPI0519464A2 (pt) | uso de certos compostos fenil-naftila que nço tÊm significante afinidade para er alfa ou beta para proteÇço de neurânios e oligodendràcitos no tratamento de esclerose méltipla | |
RS52507B (en) | APPLICATION OF SPECIFIC HISTONS FOR THE TREATMENT OF PARASITIC DISEASES | |
BR0208157A (pt) | Composições úteis para o tratamento de patologias respondendo à ativação de receptor ppar-gama | |
ECSP003458A (es) | Compuestos para tratar la obesidad | |
HN2002000099A (es) | Derivadposs de cromano 2,6 sustituidos utiles como agonistas adrenoreceptores beta - 3 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
B25A | Requested transfer of rights approved |
Owner name: JOHNSON AND JOHNSON (US) Free format text: TRANSFERIDO DE: JANSSEN PHARMACEUTICA N.V. |
|
B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
B08L | Patent application lapsed because of non payment of annual fee [chapter 8.12 patent gazette] |
Free format text: REFERENTE AO NAO RECOLHIMENTO DAS 9A E 10A ANUIDADES. |
|
B08I | Publication cancelled [chapter 8.9 patent gazette] |
Free format text: ANULADA A PUBLICACAO CODIGO 8.12 NA RPI NO 2256 DE 01/04/2014 POR TER SIDO INDEVIDA. |
|
B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE AS 9A, 10A, 11A, 12A, 13A, 14A, 15A, 16A E 17A ANUIDADES. |
|
B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2602 DE 17-11-2020 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013. |