BR0315231A - Compostos com base em glicose com afinidade para p-seletina - Google Patents

Compostos com base em glicose com afinidade para p-seletina

Info

Publication number
BR0315231A
BR0315231A BR0315231-6A BR0315231A BR0315231A BR 0315231 A BR0315231 A BR 0315231A BR 0315231 A BR0315231 A BR 0315231A BR 0315231 A BR0315231 A BR 0315231A
Authority
BR
Brazil
Prior art keywords
based compounds
selectin
glucose based
affinity glucose
selectin affinity
Prior art date
Application number
BR0315231-6A
Other languages
English (en)
Inventor
Chantal Catharina Appeldoorn
Erik Anna Leonardus Biessen
Thomas Jacobus Maria Molenaar
Theodorus Josephus Corn Berkel
Original Assignee
Yamanouchi Europ Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yamanouchi Europ Bv filed Critical Yamanouchi Europ Bv
Publication of BR0315231A publication Critical patent/BR0315231A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Abstract

"COMPOSTOS COM BASE EM GLICOSE COM AFINIDADE PARA P-SELETINA". A presente invenção se refere a determinados compostos com base em glicose que apresentam afinidade a P-seletina. Ademais, a presente invenção se refere ao uso dos referidos compostos com base em glicose para a preparação de composições farmacêuticas para o tratamento de desordens associadas a P-seletina, a conjugados, a veículos farmacêuticos, e a sistemas de envio de drogas que compreendem os referidos compostos, e ao método de determinar se o composto é capaz de se ligar a P-seletina.
BR0315231-6A 2002-10-11 2003-10-13 Compostos com base em glicose com afinidade para p-seletina BR0315231A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP02079232 2002-10-11
PCT/EP2003/011457 WO2004033473A1 (en) 2002-10-11 2003-10-13 Glucose-based compounds with affinity to p-selectin

Publications (1)

Publication Number Publication Date
BR0315231A true BR0315231A (pt) 2005-08-23

Family

ID=32088032

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0315231-6A BR0315231A (pt) 2002-10-11 2003-10-13 Compostos com base em glicose com afinidade para p-seletina

Country Status (11)

Country Link
US (1) US7304039B2 (pt)
EP (1) EP1549658B1 (pt)
JP (1) JP4603888B2 (pt)
AT (1) ATE444301T1 (pt)
AU (1) AU2003278090A1 (pt)
BR (1) BR0315231A (pt)
CA (1) CA2501842C (pt)
DE (1) DE60329511D1 (pt)
ES (1) ES2334220T3 (pt)
MX (1) MXPA05003844A (pt)
WO (1) WO2004033473A1 (pt)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011127136A1 (en) * 2010-04-06 2011-10-13 University Of Chicago Composition and methods related to modification of 5-hydroxymethylcytosine (5-hmc)
AU2011285703B2 (en) * 2010-08-04 2016-03-10 Wisconsin Alumni Research Foundation Methods and pharmaceutical compositions for treating adverse or deleterious sequellae of traumatic brain injury
US20230372492A1 (en) * 2020-10-01 2023-11-23 Mississippi State University Drugs conjugated with hexose phosphate and methods of making and using same

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994005314A1 (en) * 1992-09-08 1994-03-17 Centocor, Inc. Peptide inhibitors of leukocyte adhesion
RO117533B1 (ro) * 1993-05-14 2002-04-30 Cytel Corp San Diego DERIVATI DE ANALOGI SIALIL LeX INHIBITORI AI ADEZIUNII CELULARE SI COMPOZITIE FARMACEUTICA CU ACESTIA
JPH10508580A (ja) 1994-09-20 1998-08-25 ファルマシア・アンド・アップジョン・カンパニー Ｅおよびｐセレクチンに対するリガンドのオリゴ糖構造
JP2000516224A (ja) 1996-08-08 2000-12-05 ノバルティス アクチエンゲゼルシャフト 修飾オリゴサッカライド
US5830871A (en) * 1996-10-28 1998-11-03 The Scripps Research Institute Inhibitors of E-, P- and L-selectin binding
WO1998008854A2 (en) * 1996-08-26 1998-03-05 Novartis Ag Sugar derivatives as sialyl lewis x mimetics
WO1999010359A2 (en) * 1997-08-26 1999-03-04 Novartis Ag Liposomic based sialyl lewis x mimetics
EP1288222A1 (en) 2001-09-03 2003-03-05 Yamanouchi Europe B.V. Peptidic compounds selectively binding to P-selectin
CA2493471C (en) 2002-08-09 2013-02-12 Yamanouchi Europe B.V. Compounds binding to p-selectin

Also Published As

Publication number Publication date
US20050261207A1 (en) 2005-11-24
CA2501842A1 (en) 2004-04-22
WO2004033473A1 (en) 2004-04-22
US7304039B2 (en) 2007-12-04
ATE444301T1 (de) 2009-10-15
CA2501842C (en) 2012-07-17
JP2006503876A (ja) 2006-02-02
ES2334220T3 (es) 2010-03-08
JP4603888B2 (ja) 2010-12-22
MXPA05003844A (es) 2005-06-22
DE60329511D1 (de) 2009-11-12
EP1549658A1 (en) 2005-07-06
AU2003278090A1 (en) 2004-05-04
EP1549658B1 (en) 2009-09-30

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 4A , 5A , 6A E 7A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2073 DE 28/09/2010.