BR0315042A - Terapia para o tratamento de aterosclerose baseada em imunização passiva por peptìdeo - Google Patents
Terapia para o tratamento de aterosclerose baseada em imunização passiva por peptìdeoInfo
- Publication number
- BR0315042A BR0315042A BR0315042-9A BR0315042A BR0315042A BR 0315042 A BR0315042 A BR 0315042A BR 0315042 A BR0315042 A BR 0315042A BR 0315042 A BR0315042 A BR 0315042A
- Authority
- BR
- Brazil
- Prior art keywords
- passive
- treatment
- therapy
- atherosclerosis
- peptide immunization
- Prior art date
Links
- 238000002649 immunization Methods 0.000 title abstract 4
- 230000003053 immunization Effects 0.000 title abstract 4
- 201000001320 Atherosclerosis Diseases 0.000 title abstract 3
- 108090000765 processed proteins & peptides Proteins 0.000 title 1
- 238000002560 therapeutic procedure Methods 0.000 title 1
- 238000000034 method Methods 0.000 abstract 2
- 101710095342 Apolipoprotein B Proteins 0.000 abstract 1
- 102100040202 Apolipoprotein B-100 Human genes 0.000 abstract 1
- 241000124008 Mammalia Species 0.000 abstract 1
- 239000012634 fragment Substances 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/775—Apolipopeptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
- C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
- C07K2317/622—Single chain antibody (scFv)
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Immunology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE0202959A SE0202959D0 (sv) | 2002-10-04 | 2002-10-04 | Peptide-Base passive immunization therapy for treatment of atherosclerosis |
| SE0302312A SE0302312D0 (sv) | 2002-10-04 | 2003-08-27 | Peptide-based passive immunization therapy for treatment of atherosclerosis |
| PCT/SE2003/001469 WO2004030698A1 (en) | 2002-10-04 | 2003-09-22 | Peptide-based passive immunization therapy for treatment of atherosclerosis |
| PCT/SE2003/001547 WO2004030607A2 (en) | 2002-10-04 | 2003-10-06 | Peptide-based passive immunization therapy for treatment of atherosclerosis |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR0315042A true BR0315042A (pt) | 2005-08-23 |
Family
ID=28677712
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR0315042-9A BR0315042A (pt) | 2002-10-04 | 2003-10-06 | Terapia para o tratamento de aterosclerose baseada em imunização passiva por peptìdeo |
Country Status (19)
| Country | Link |
|---|---|
| US (6) | US7468183B2 (enExample) |
| EP (3) | EP2361633A1 (enExample) |
| JP (5) | JP2006506450A (enExample) |
| CN (3) | CN102172400A (enExample) |
| AT (1) | ATE498407T1 (enExample) |
| AU (2) | AU2003263712A1 (enExample) |
| BR (1) | BR0315042A (enExample) |
| CY (1) | CY1112229T1 (enExample) |
| DE (1) | DE60336068D1 (enExample) |
| DK (1) | DK1545609T3 (enExample) |
| EE (1) | EE200500012A (enExample) |
| ES (1) | ES2387423T3 (enExample) |
| PL (1) | PL376964A1 (enExample) |
| PT (1) | PT1545609E (enExample) |
| RU (2) | RU2322260C2 (enExample) |
| SE (1) | SE0302312D0 (enExample) |
| SI (1) | SI1545609T1 (enExample) |
| TW (2) | TW200835517A (enExample) |
| WO (1) | WO2004030698A1 (enExample) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1531162A1 (en) * | 2003-11-14 | 2005-05-18 | Heinz Vollmers | Adenocarcinoma specific antibody SAM-6, and uses thereof |
| DE10353175A1 (de) * | 2003-11-14 | 2005-06-16 | Müller-Hermelink, Hans Konrad, Prof. Dr. | Humaner monoklonaler Antikörper mit fettsenkender Wirkung |
| GB0517878D0 (en) * | 2005-09-02 | 2005-10-12 | Bioinvent Int Ab | Immunotherapeutic treatment |
| CA2710775A1 (en) * | 2007-12-28 | 2009-07-09 | Bioinvent International Ab | Formulation |
| CN110317272A (zh) | 2008-10-14 | 2019-10-11 | 霍夫曼-拉罗奇有限公司 | 免疫球蛋白变体及其用途 |
| CA2751571A1 (en) * | 2009-02-09 | 2010-08-12 | Patrys Limited | Sam-6 variants, target and methods of use |
| US8609605B2 (en) | 2009-03-17 | 2013-12-17 | Cardiovax, Llc | Immunomodulatory methods for treatment of atherosclerosis via inhibition of CD4+ T cell response to APOB100 |
| CU23736A1 (es) | 2009-05-04 | 2011-11-15 | Centro Inmunologia Molecular | Anticuerpos que reconocen sulfatidos y proteoglicanos sulfatados y su uso |
| JP2013503195A (ja) * | 2009-08-28 | 2013-01-31 | ジェネンテック， インコーポレイテッド | 抗酸化ｌｄｌ抗体を用いた治療方法 |
| US9125850B2 (en) | 2009-11-14 | 2015-09-08 | Cardio Vax, Llc | Immunomodulatory methods and systems for treatment and/or prevention of atherosclerosis |
| WO2012065133A1 (en) | 2010-11-12 | 2012-05-18 | Cedars-Sinai Medical Center | Immunomodulatory methods and systems for treatment and/or prevention of aneurysms |
| AU2011336997A1 (en) | 2010-11-12 | 2013-05-30 | Cedars-Sinai Medical Center | Immunomodulatory methods and systems for treatment and/or prevention of hypertension |
| AU2013277372B2 (en) * | 2012-06-21 | 2018-03-29 | Indiana University Research And Technology Corporation | Analogs of glucagon exhibiting GIP receptor activity |
| US10858422B2 (en) | 2016-05-31 | 2020-12-08 | Abcentra, Llc | Methods for treating systemic lupus erythematosus with an anti-apolipoprotein B antibody |
| EP3463416A1 (en) | 2016-05-31 | 2019-04-10 | CardioVax, LLC | Methods for diagnosing and treating systemic lupus erythematosus |
| CN110950952A (zh) * | 2019-12-17 | 2020-04-03 | 东莞市东阳光生物药研发有限公司 | 制备抗体的方法 |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4970144A (en) * | 1984-12-31 | 1990-11-13 | International Genetic Engineering | Peptide fragments of human apolipoprotein, type-specific antibodies and methods of use |
| US4946778A (en) | 1987-09-21 | 1990-08-07 | Genex Corporation | Single polypeptide chain binding molecules |
| US5972890A (en) * | 1988-05-02 | 1999-10-26 | New England Deaconess Hospital Corporation | Synthetic peptides for arterial imaging |
| US5196324A (en) * | 1989-12-15 | 1993-03-23 | Eli Lilly And Company | Monoclonal antibodies reactive with a human atheroma associated antigen |
| SE9103701D0 (sv) * | 1991-12-13 | 1991-12-13 | Kabi Pharmacia Ab | Apolipoprotein |
| WO1994000592A1 (en) * | 1992-06-26 | 1994-01-06 | Exocell, Inc. | Monoclonal antibodies against glycated low density lipoprotein |
| US5678548A (en) | 1995-07-20 | 1997-10-21 | The United States Of America As Represented By The Department Of Health And Human Services | System and method for performing in vivo imaging and oxymetry and FT microscopy by pulsed radiofrequency electron paramagnetic resonance |
| CN1206421A (zh) * | 1995-11-01 | 1999-01-27 | 科斯药品公司 | 载脂蛋白e2和阿尔采默氏病的治疗 |
| KR0185334B1 (ko) * | 1995-11-02 | 1999-04-01 | 김은영 | 인간 혈장 아포지단백질 비-100에 결합하는 생쥐 항체를 암호하는 씨디엔에이 |
| GB9620153D0 (en) | 1996-09-27 | 1996-11-13 | Univ Strathclyde | Non-naturally occurring lipoprotein particle |
| GB9701425D0 (en) | 1997-01-24 | 1997-03-12 | Bioinvent Int Ab | A method for in vitro molecular evolution of protein function |
| GB9705831D0 (en) * | 1997-03-20 | 1997-05-07 | Univ Leicester | Oxidised ldl |
| US6635623B1 (en) | 1997-06-13 | 2003-10-21 | Baylor College Of Medicine | Lipoproteins as nucleic acid vectors |
| US6225070B1 (en) | 1997-08-07 | 2001-05-01 | The Regents Of The University Of California | Antibodies to oxidation-specific epitopes on lipoprotein and methods for their use in detecting, monitoring and inhibiting the growth of atheroma |
| KR20010022812A (ko) * | 1997-08-12 | 2001-03-26 | 리드 비.브이. | 인자의 변형능력을 측정하는 방법 |
| US6156315A (en) | 1997-10-10 | 2000-12-05 | The Trustees Of Columbia University In The City Of New York | Method for inhibiting the binding of low density lipoprotein to blood vessel matrix |
| WO2000002920A1 (en) | 1998-07-13 | 2000-01-20 | University Of Otago | Inhibition of lipoprotein formation |
| EP1224461B1 (en) * | 1999-10-26 | 2011-04-20 | The Regents of The University of California | Reagents and methods for diagnosing, imaging and treating atherosclerotic disease |
| CZ20022971A3 (cs) * | 2000-03-03 | 2003-02-12 | Smithkline Beecham Biologicals S. A. | Vakcinační prostředek vhodný pro léčbu aterosklerózy |
| SE0103754L (sv) * | 2001-04-05 | 2002-10-06 | Forskarpatent I Syd Ab | Peptider från apolipoprotein B, användning därav immunisering, diagnosmetod eller terapeutisk behandling av ischemiska kardiovaskulära sjukdomar, samt farmaceutisk komposition och vaccin innehållande sådan peptid |
| US20030105003A1 (en) * | 2001-04-05 | 2003-06-05 | Jan Nilsson | Peptide-based immunization therapy for treatment of atherosclerosis and development of peptide-based assay for determination of immune responses against oxidized low density lipoprotein |
| JP4159300B2 (ja) | 2001-07-05 | 2008-10-01 | 株式会社リコー | 画像定着装置及び画像形成装置 |
-
2003
- 2003-08-27 SE SE0302312A patent/SE0302312D0/xx unknown
- 2003-09-22 AU AU2003263712A patent/AU2003263712A1/en not_active Abandoned
- 2003-09-22 WO PCT/SE2003/001469 patent/WO2004030698A1/en not_active Ceased
- 2003-09-25 TW TW097111600A patent/TW200835517A/zh unknown
- 2003-09-25 TW TW092126462A patent/TWI299666B/zh not_active IP Right Cessation
- 2003-10-03 US US10/679,032 patent/US7468183B2/en not_active Expired - Lifetime
- 2003-10-06 BR BR0315042-9A patent/BR0315042A/pt not_active IP Right Cessation
- 2003-10-06 PL PL376964A patent/PL376964A1/pl not_active Application Discontinuation
- 2003-10-06 EP EP10075394A patent/EP2361633A1/en not_active Withdrawn
- 2003-10-06 CN CN2010101282350A patent/CN102172400A/zh active Pending
- 2003-10-06 PT PT03748843T patent/PT1545609E/pt unknown
- 2003-10-06 EP EP03748843A patent/EP1545609B1/en not_active Expired - Lifetime
- 2003-10-06 EP EP10075393A patent/EP2359848A1/en not_active Withdrawn
- 2003-10-06 DE DE60336068T patent/DE60336068D1/de not_active Expired - Lifetime
- 2003-10-06 JP JP2005500961A patent/JP2006506450A/ja active Pending
- 2003-10-06 DK DK03748843.4T patent/DK1545609T3/da active
- 2003-10-06 CN CN2011102300859A patent/CN102380097A/zh active Pending
- 2003-10-06 AT AT03748843T patent/ATE498407T1/de active
- 2003-10-06 ES ES03748843T patent/ES2387423T3/es not_active Expired - Lifetime
- 2003-10-06 SI SI200331982T patent/SI1545609T1/sl unknown
- 2003-10-06 EE EEP200500012A patent/EE200500012A/xx unknown
- 2003-10-06 CN CN2010101282346A patent/CN102319429A/zh active Pending
- 2003-10-06 RU RU2005113235/15A patent/RU2322260C2/ru not_active IP Right Cessation
-
2005
- 2005-12-30 US US11/323,123 patent/US7601353B2/en not_active Expired - Fee Related
-
2006
- 2006-12-19 US US11/612,591 patent/US20080008702A1/en not_active Abandoned
-
2007
- 2007-10-30 US US11/928,221 patent/US7521046B2/en not_active Expired - Fee Related
- 2007-11-02 RU RU2007140978/15A patent/RU2007140978A/ru not_active Application Discontinuation
-
2008
- 2008-10-27 US US12/258,745 patent/US8114966B2/en not_active Expired - Fee Related
-
2009
- 2009-03-31 AU AU2009201260A patent/AU2009201260B2/en not_active Ceased
-
2010
- 2010-01-07 JP JP2010001794A patent/JP2010136721A/ja active Pending
- 2010-01-07 JP JP2010001796A patent/JP2010104375A/ja active Pending
- 2010-01-07 JP JP2010001795A patent/JP2010104374A/ja active Pending
- 2010-06-22 JP JP2010141960A patent/JP2010222378A/ja active Pending
-
2011
- 2011-03-21 CY CY20111100305T patent/CY1112229T1/el unknown
- 2011-10-13 US US13/272,297 patent/US20120070426A1/en not_active Abandoned
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B25A | Requested transfer of rights approved |
Owner name: BIOINVENT INTERNATIONAL AB (SE) Free format text: TRANSFERIDO DE: FORSKARPATENT I SYD AB |
|
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 10A ANUIDADE. |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2256 DE 01/04/2014. |