BR0314549A - Processo para preparar haloalquil-pirimidinas - Google Patents

Processo para preparar haloalquil-pirimidinas

Info

Publication number
BR0314549A
BR0314549A BR0314549-2A BR0314549A BR0314549A BR 0314549 A BR0314549 A BR 0314549A BR 0314549 A BR0314549 A BR 0314549A BR 0314549 A BR0314549 A BR 0314549A
Authority
BR
Brazil
Prior art keywords
pyrimidines
haloalkyl
preparing
preparing haloalkyl
benzimidazole
Prior art date
Application number
BR0314549-2A
Other languages
English (en)
Inventor
Stephane Caron
Nga My Do
Ruth Elsbree Mcdermott
Robert Alan Singer
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of BR0314549A publication Critical patent/BR0314549A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

"PROCESSO PARA PREPARAR HALOALQUILPIRIMIDINAS". A invenção refere-se a um processo para produzir haloalquilpirimidinas como intermediários na produção de derivados de benzimidazol e/ou piridilimidazol tendo elevada seletividade e/ou elevada afinidade para o local benzodiazepina dos receptores de GABA~ A~.
BR0314549-2A 2002-09-30 2003-09-18 Processo para preparar haloalquil-pirimidinas BR0314549A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US41513002P 2002-09-30 2002-09-30
PCT/IB2003/004100 WO2004029052A1 (en) 2002-09-30 2003-09-18 Process for preparing haloalkyl pyrimidines

Publications (1)

Publication Number Publication Date
BR0314549A true BR0314549A (pt) 2005-08-09

Family

ID=32043423

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0314549-2A BR0314549A (pt) 2002-09-30 2003-09-18 Processo para preparar haloalquil-pirimidinas

Country Status (11)

Country Link
US (1) US20040063938A1 (pt)
EP (1) EP1549649B1 (pt)
JP (1) JP2006503065A (pt)
AT (1) ATE334130T1 (pt)
AU (1) AU2003259529A1 (pt)
BR (1) BR0314549A (pt)
CA (1) CA2500117A1 (pt)
DE (1) DE60307120T2 (pt)
ES (1) ES2266911T3 (pt)
MX (1) MXPA05002122A (pt)
WO (1) WO2004029052A1 (pt)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ME02663B (me) 2010-10-06 2017-06-20 Glaxosmithkline Llc Derivati benzimidazola kao inhibitori pi3 kinaze
KR101421032B1 (ko) * 2012-12-28 2014-07-22 주식회사 레고켐 바이오사이언스 (2-메틸-1-(3-메틸벤질)-1Ｈ-벤조[d]이미다졸-5일)(피페리딘-5-일)메탄온의 제조방법
CN103113306A (zh) * 2013-03-07 2013-05-22 同济大学 一种合成氮茚化合物nps-1577的方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69824632T2 (de) * 1997-11-12 2005-06-09 Mitsubishi Chemical Corp. Purinderivate und medikamente, welche dieselben als aktiven bestandteil enthalten
US6037470A (en) * 1997-12-12 2000-03-14 Euro-Celtique S.A. Purine compounds having PDE IV inhibitory activity and methods of synthesis
PA8535601A1 (es) * 2000-12-21 2002-11-28 Pfizer Derivados benzimidazol y piridilimidazol como ligandos para gabaa

Also Published As

Publication number Publication date
EP1549649B1 (en) 2006-07-26
JP2006503065A (ja) 2006-01-26
ES2266911T3 (es) 2007-03-01
DE60307120D1 (de) 2006-09-07
AU2003259529A1 (en) 2004-04-19
US20040063938A1 (en) 2004-04-01
WO2004029052A1 (en) 2004-04-08
ATE334130T1 (de) 2006-08-15
MXPA05002122A (es) 2005-06-06
DE60307120T2 (de) 2007-01-04
CA2500117A1 (en) 2004-04-08
EP1549649A1 (en) 2005-07-06

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 6A E 7A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2069 DE 31/08/2010.