BR0313048A - Uso de alquilfosfocolinas em combinação com medicamentos antitumorais - Google Patents

Uso de alquilfosfocolinas em combinação com medicamentos antitumorais

Info

Publication number
BR0313048A
BR0313048A BR0313048-7A BR0313048A BR0313048A BR 0313048 A BR0313048 A BR 0313048A BR 0313048 A BR0313048 A BR 0313048A BR 0313048 A BR0313048 A BR 0313048A
Authority
BR
Brazil
Prior art keywords
combination
alkylphosphocholines
antitumor drugs
alkylphosphocolins
alkylphosphocolines
Prior art date
Application number
BR0313048-7A
Other languages
English (en)
Portuguese (pt)
Inventor
Juergen Engel
Eckhard Guenther
Herbert Sindermann
Original Assignee
Zentaris Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zentaris Gmbh filed Critical Zentaris Gmbh
Publication of BR0313048A publication Critical patent/BR0313048A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/683—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
    • A61K31/685—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
BR0313048-7A 2002-07-30 2003-07-29 Uso de alquilfosfocolinas em combinação com medicamentos antitumorais BR0313048A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US39961502P 2002-07-30 2002-07-30
PCT/EP2003/008346 WO2004012744A1 (de) 2002-07-30 2003-07-29 Anwendung von alkylphosphocholinen in kombination mit antitumormedikamenten

Publications (1)

Publication Number Publication Date
BR0313048A true BR0313048A (pt) 2005-06-14

Family

ID=31495746

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0313048-7A BR0313048A (pt) 2002-07-30 2003-07-29 Uso de alquilfosfocolinas em combinação com medicamentos antitumorais

Country Status (26)

Country Link
US (3) US8389497B2 (enExample)
EP (2) EP1545553B1 (enExample)
JP (1) JP2005535688A (enExample)
KR (3) KR101066804B1 (enExample)
CN (1) CN1302780C (enExample)
AR (1) AR040717A1 (enExample)
AT (1) ATE516036T1 (enExample)
AU (2) AU2003253350B2 (enExample)
BR (1) BR0313048A (enExample)
CA (1) CA2493023C (enExample)
CY (1) CY1111902T1 (enExample)
DK (1) DK1545553T3 (enExample)
ES (1) ES2369535T3 (enExample)
HR (1) HRP20050184B1 (enExample)
IL (1) IL166329A (enExample)
MX (1) MXPA05001203A (enExample)
NO (1) NO335196B1 (enExample)
NZ (1) NZ538428A (enExample)
PL (1) PL375493A1 (enExample)
PT (1) PT1545553E (enExample)
RU (1) RU2005105693A (enExample)
SI (1) SI1545553T1 (enExample)
TW (1) TWI332007B (enExample)
UA (1) UA82322C2 (enExample)
WO (1) WO2004012744A1 (enExample)
ZA (1) ZA200500453B (enExample)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8383605B2 (en) 2002-07-30 2013-02-26 Aeterna Zentaris Gmbh Use of alkylphosphocholines in combination with antimetabolites for the treatment of benign and malignant oncoses in humans and mammals
TWI332007B (en) 2002-07-30 2010-10-21 Aeterna Zentaris Gmbh Use of alkylphosphocholines in combination with antitumor medicaments for the treatment of benign and malignant oncoses in humans and animals
DE10324911B4 (de) 2003-05-30 2005-08-18 Siemens Ag Röntgenvorrichtung mit partiellem digitalem Detektor und Verfahren zum Betrieb einer solchen
WO2006081452A2 (en) * 2005-01-28 2006-08-03 Robert Birch Co-administration of perifosine with chemotherapeutics
WO2009018233A1 (en) * 2007-07-30 2009-02-05 Ardea Biosciences, Inc. Derivatives of n-(arylamino) sulfonamides including polymorphs as inhibitors of mek as well as compositions, methods of use and methods for preparing the same
JP5232009B2 (ja) * 2005-12-19 2013-07-10 エテルナ ツェンタリス ゲゼルシャフト ミット ベシュレンクテル ハフツング 低減された細胞毒性を有するアルキルリン脂質誘導体並びにそれらの使用
EP1800684A1 (en) * 2005-12-20 2007-06-27 Zentaris GmbH Novel alkyl phospholipid derivatives and uses thereof
CN101340918B (zh) * 2005-12-19 2012-10-03 阿特纳赞塔里斯有限公司 具有降低细胞毒性的新烷基磷脂衍生物及其用途
US8703179B2 (en) 2006-05-11 2014-04-22 Kimberly-Clark Worldwide, Inc. Mucosal formulation
MX2011006167A (es) * 2008-12-11 2011-07-28 Abraxis Bioscience Llc Combinaciones y modos de administracion de agentes terapeuticos y terapia de combinacion.
MX2011011596A (es) 2010-03-31 2012-02-01 Keryx Biopharmaceuticals Inc Perifosina y capecitabina como un tratamiento combinado para cancer.

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE59205998D1 (de) * 1991-07-04 1996-05-23 Asta Medica Ag Arzneimittel mit antineoplastischer Wirkung enthaltend als Wirkstoff Octadecyl-[2-(N-methylpiperidino)-ethyl]-phosphat und Verfahren zu dessen Herstellung
US5942639A (en) * 1991-07-04 1999-08-24 Asta Medica Aktiengesellschaft Process for the preparation of alkylphosphocholines and the production thereof in pure form
US6172050B1 (en) * 1992-07-11 2001-01-09 Asta Medica Aktiengesellschaft Phospholipid derivatives
JP3079993B2 (ja) * 1996-03-27 2000-08-21 日本電気株式会社 真空マイクロデバイスおよびその製造方法
DE19650778C2 (de) * 1996-12-06 2001-01-04 Asta Medica Ag Verwendung von Dopaminrezeptor-Antagonisten in der palliativen Tumortherapie
PL189654B1 (pl) * 1998-01-22 2005-09-30 Zentaris Gmbh Zastosowanie miltefosyny do wytwarzania leków
PT1135193E (pt) * 1998-12-04 2003-01-31 Max Delbrueck Centrum Agentes para o tratamento de tumores a base de lipossomas e compreendendo tamoxifeno
CA2356736A1 (en) * 1998-12-21 2000-06-29 Inkeysa. S.A. Use of etherlysophospholipids as antiinflammatory agents
EP2762140B1 (en) * 2001-02-19 2017-03-22 Novartis AG Treatment of solid brain tumours with a rapamycin derivative
PL365285A1 (en) * 2001-03-23 2004-12-27 Shire Biochem Inc. Pharmaceutical combinations for the treatment of cancer comprising dioxolane nucleoside analogs
WO2003005522A1 (es) 2001-07-04 2003-01-16 Acuna Arturo Tapones para sellado de ductos para redes electricas, telefonicas y de fibra optica.
US20060084612A1 (en) * 2002-01-02 2006-04-20 Geroni Maria C Combined therapy against tumors comprising substituted acryloyl distamycin derivatives and protein kinase (serine/threonine kinase) inhibitors
TWI332007B (en) 2002-07-30 2010-10-21 Aeterna Zentaris Gmbh Use of alkylphosphocholines in combination with antitumor medicaments for the treatment of benign and malignant oncoses in humans and animals
WO2005000318A2 (en) * 2003-06-23 2005-01-06 Neopharm, Inc. Method of inducing apoptosis and inhibiting cardiolipin synthesis
WO2006081452A2 (en) 2005-01-28 2006-08-03 Robert Birch Co-administration of perifosine with chemotherapeutics
CN101340918B (zh) * 2005-12-19 2012-10-03 阿特纳赞塔里斯有限公司 具有降低细胞毒性的新烷基磷脂衍生物及其用途
MX2011011596A (es) * 2010-03-31 2012-02-01 Keryx Biopharmaceuticals Inc Perifosina y capecitabina como un tratamiento combinado para cancer.

Also Published As

Publication number Publication date
HRP20050184A2 (en) 2005-04-30
PL375493A1 (en) 2005-11-28
DK1545553T3 (da) 2011-09-12
US8389497B2 (en) 2013-03-05
JP2005535688A (ja) 2005-11-24
IL166329A0 (en) 2006-01-15
NO20051040L (no) 2005-02-25
US8507710B2 (en) 2013-08-13
IL166329A (en) 2012-08-30
US20100190738A1 (en) 2010-07-29
KR20130016413A (ko) 2013-02-14
TWI332007B (en) 2010-10-21
CY1111902T1 (el) 2015-11-04
EP1545553A1 (de) 2005-06-29
US20100189784A1 (en) 2010-07-29
CN1302780C (zh) 2007-03-07
SI1545553T1 (sl) 2011-09-30
HRP20050184B1 (hr) 2014-04-11
KR20110102485A (ko) 2011-09-16
US8551977B2 (en) 2013-10-08
RU2005105693A (ru) 2005-07-10
KR101066804B1 (ko) 2011-09-22
AU2003253350B2 (en) 2008-06-26
CA2493023A1 (en) 2004-02-12
ATE516036T1 (de) 2011-07-15
NO335196B1 (no) 2014-10-20
PT1545553E (pt) 2011-09-12
WO2004012744A1 (de) 2004-02-12
ZA200500453B (en) 2005-08-31
KR20050026028A (ko) 2005-03-14
EP2301551A1 (de) 2011-03-30
TW200404073A (en) 2004-03-16
MXPA05001203A (es) 2005-06-08
CN1671397A (zh) 2005-09-21
CA2493023C (en) 2012-01-31
NZ538428A (en) 2006-09-29
AR040717A1 (es) 2005-04-20
EP1545553B1 (de) 2011-07-13
AU2008203060B2 (en) 2011-04-21
ES2369535T3 (es) 2011-12-01
AU2003253350A1 (en) 2004-02-23
HK1080751A1 (en) 2006-05-04
US20040097470A1 (en) 2004-05-20
AU2008203060A1 (en) 2008-07-31
UA82322C2 (uk) 2008-04-10

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Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B25D Requested change of name of applicant approved

Owner name: AETERNA ZENTARIS GMBH (DE)

Free format text: NOME ALTERADO DE : ZENTARIS GMBH.

B25G Requested change of headquarter approved

Owner name: AETERNA ZENTARIS GMBH (DE)

Free format text: ENDERECO ALTERADO CONFORME PET NO 020060058923 - RJ DE 27/04/2006.

B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B07F Notification of approval that there is no relation to art. 229 of lpi (pipeline patents) [chapter 7.6 patent gazette]

Free format text: NOTIFICACAO DE NAO ANUENCIA RELACIONADA COM O ART. 229 DA LPI

B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 12A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2317 DE 02-06-2015 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.