BR0303493A - Combinação de polìmero de antibiótico/antibióticos - Google Patents
Combinação de polìmero de antibiótico/antibióticosInfo
- Publication number
- BR0303493A BR0303493A BR0303493-3A BR0303493A BR0303493A BR 0303493 A BR0303493 A BR 0303493A BR 0303493 A BR0303493 A BR 0303493A BR 0303493 A BR0303493 A BR 0303493A
- Authority
- BR
- Brazil
- Prior art keywords
- antibiotic
- iii
- water
- salt
- lincosamide
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L31/16—Biologically active materials, e.g. therapeutic substances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/28—Materials for coating prostheses
- A61L27/34—Macromolecular materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/54—Biologically active materials, e.g. therapeutic substances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L29/00—Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
- A61L29/08—Materials for coatings
- A61L29/085—Macromolecular materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L29/00—Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
- A61L29/14—Materials characterised by their function or physical properties, e.g. lubricating compositions
- A61L29/16—Biologically active materials, e.g. therapeutic substances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/08—Materials for coatings
- A61L31/10—Macromolecular materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/404—Biocides, antimicrobial agents, antiseptic agents
- A61L2300/406—Antibiotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
- A61L2300/602—Type of release, e.g. controlled, sustained, slow
Abstract
"COMBINAçãO DE POLìMERO DE ANTIBIóTICO/ANTIBIóTICOS". A presente invenção refere-se a uma combinação de polímero de antibiótico/antibióticos, que sob condições fisiológicas assegura uma liberação contínua de antibióticos durante um espaço de tempo de vários dias e que pode ser empregada na medicina humana e na veterinária. A invenção baseia-se no resultado surpreendente, que misturas de polímeros homogêneas, constituídas de um ou mais polímeros não-iónicos, hidrófobos dos grupos do poli(cloreto de vinila), do poli(cloreto de vinila) pós-clorado, do poli(cloreto de vinilideno), do poli(fluoreto de vinila), do poli(fluoreto de vinilideno) e dos co-polímeros de cloreto de vinila e de um ou mais monómeros não-iónicos e de um ou mais polímeros hidrófilos dos grupos dos poliéteres, de um ou mais sais antibióticos pouco solúveis em água dos grupos dos antibióticos aminoglicosídeo, dos antibióticos lincosamida, dos antibióticos tetraciclina, dos antibióticos glicopeptídeo, dos antibióticos quinolona e da clorhexidina são suspensos e essa suspensão forma compósitos, que no meio aquoso mostram uma liberação da substância ativa durante um espaço de tempo de dias.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE10242476A DE10242476B4 (de) | 2002-09-11 | 2002-09-11 | Antibiotikum-/Antibiotika-Polymer-Kombination |
Publications (1)
Publication Number | Publication Date |
---|---|
BR0303493A true BR0303493A (pt) | 2004-09-08 |
Family
ID=31724720
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR0303493-3A BR0303493A (pt) | 2002-09-11 | 2003-09-10 | Combinação de polìmero de antibiótico/antibióticos |
Country Status (13)
Country | Link |
---|---|
US (1) | US20040137065A1 (pt) |
EP (1) | EP1398046B1 (pt) |
JP (1) | JP4528507B2 (pt) |
CN (1) | CN1494925A (pt) |
AT (1) | ATE300319T1 (pt) |
AU (1) | AU2003244544B2 (pt) |
BR (1) | BR0303493A (pt) |
CA (1) | CA2438346C (pt) |
DE (2) | DE10242476B4 (pt) |
DK (1) | DK1398046T3 (pt) |
ES (1) | ES2242920T3 (pt) |
PT (1) | PT1398046E (pt) |
ZA (1) | ZA200307059B (pt) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7279174B2 (en) * | 2003-05-08 | 2007-10-09 | Advanced Cardiovascular Systems, Inc. | Stent coatings comprising hydrophilic additives |
EP1781264B1 (en) | 2004-08-04 | 2013-07-24 | Evonik Corporation | Methods for manufacturing delivery devices and devices thereof |
US20070197548A1 (en) * | 2006-02-17 | 2007-08-23 | Murthy Yerramilli V S | Fluoroquinolone compositions |
US20070196398A1 (en) * | 2006-02-17 | 2007-08-23 | Murthy Yerramilli V S | Fluoroquinolone fatty acid salt compositions |
DE102006033312A1 (de) * | 2006-07-17 | 2008-01-31 | Heraeus Kulzer Gmbh | Dentales Implantatsystemteil mit einer Beschichtung |
EP2222281B1 (en) | 2007-12-20 | 2018-12-05 | Evonik Corporation | Process for preparing microparticles having a low residual solvent volume |
CA2720721A1 (en) * | 2008-04-07 | 2009-10-15 | Interface Biologics, Inc. | Combination therapy for the treatment of bacterial infections |
US20100069854A1 (en) * | 2008-09-12 | 2010-03-18 | Onajite Okoh | Elastomeric Devices Containing Chlorhexidine/Fatty Acid Salts Made From Fatty Acids of 12 to 18 Carbons |
US9763697B2 (en) * | 2008-12-16 | 2017-09-19 | DePuy Synthes Products, Inc. | Anti-infective spinal rod with surface features |
EP2373270B8 (en) | 2009-01-07 | 2023-04-12 | entrotech life sciences, inc. | Chlorhexidine-containing antimicrobial laminates |
US9333280B2 (en) | 2009-02-25 | 2016-05-10 | Teleflex Medical Incorporated | Stabilized enzyme compositions |
US8545459B2 (en) * | 2009-02-25 | 2013-10-01 | Teleflex Medical Incorporated | Stabilized enzyme compositions |
US20100234815A1 (en) * | 2009-03-11 | 2010-09-16 | Teleflex Medical Incorporated | Stable melt processable chlorhexidine compositions |
DE102010020940B4 (de) * | 2010-05-19 | 2014-09-25 | Heraeus Medical Gmbh | Antibiotische Beschichtung |
US8834772B2 (en) | 2011-12-07 | 2014-09-16 | Biomet Manufacturing, Llc | Antimicrobial methacrylate cements |
US9386772B2 (en) * | 2012-02-14 | 2016-07-12 | Allegiance Corporation | Antimicrobial elastomeric articles |
US11039615B2 (en) | 2014-04-18 | 2021-06-22 | Entrotech Life Sciences, Inc. | Methods of processing chlorhexidine-containing polymerizable compositions and antimicrobial articles formed thereby |
CN104910259A (zh) * | 2015-06-02 | 2015-09-16 | 苏州纳微科技有限公司 | 一种替考拉宁的层析纯化方法 |
CN110463719A (zh) * | 2018-12-29 | 2019-11-19 | 黑龙江大学 | 环丙沙星金属配合物-聚烯醇复合物及其制备方法和应用 |
CN114569588B (zh) * | 2022-02-16 | 2023-09-26 | 湖南大学 | 洗必泰-万古霉素协同靶向抗菌应用 |
Family Cites Families (30)
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---|---|---|---|---|
US3566874A (en) * | 1968-08-13 | 1971-03-02 | Nat Patent Dev Corp | Catheter |
US3857932A (en) * | 1970-09-09 | 1974-12-31 | F Gould | Dry hydrophilic acrylate or methacrylate polymer prolonged release drug implants |
DE2320373B2 (de) * | 1973-04-21 | 1978-04-06 | Merck Patent Gmbh, 6100 Darmstadt | Antibioticahaltiges Mittel und seine Verwendung als chirurgisches Kunststoffmaterial |
DE2511122B2 (de) * | 1975-03-14 | 1977-06-08 | Vorprodukt fuer die zubereitung von knochenzement | |
US4479795A (en) * | 1979-06-29 | 1984-10-30 | The Procter & Gamble Company | Antimicrobial polymer compositions |
US4603152A (en) * | 1982-11-05 | 1986-07-29 | Baxter Travenol Laboratories, Inc. | Antimicrobial compositions |
US4879135A (en) * | 1984-07-23 | 1989-11-07 | University Of Medicine And Dentistry Of New Jersey | Drug bonded prosthesis and process for producing same |
US4917686A (en) * | 1985-12-16 | 1990-04-17 | Colorado Biomedical, Inc. | Antimicrobial device and method |
IL78826A (en) * | 1986-05-19 | 1991-05-12 | Yissum Res Dev Co | Precursor composition for the preparation of a biodegradable implant for the sustained release of an active material and such implants prepared therefrom |
US4895566A (en) * | 1986-07-25 | 1990-01-23 | C. R. Bard, Inc. | Coating medical devices with cationic antibiotics |
JPS63314248A (ja) * | 1986-12-25 | 1988-12-22 | Sumitomo Electric Ind Ltd | 医用塩化ビニル樹脂部材の製造方法 |
US4846844A (en) * | 1987-08-31 | 1989-07-11 | Eli Lilly And Company | Antimicrobial coated implants |
US5019378A (en) * | 1987-12-29 | 1991-05-28 | Cuno, Incorporated | Elastomeric composition containing therapeutic agents and articles manufactured therefrom |
US5019096A (en) * | 1988-02-11 | 1991-05-28 | Trustees Of Columbia University In The City Of New York | Infection-resistant compositions, medical devices and surfaces and methods for preparing and using same |
US5438076A (en) * | 1988-05-03 | 1995-08-01 | Perio Products, Ltd. | Liquid polymer composition, and method of use |
US5330746A (en) * | 1988-05-03 | 1994-07-19 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Dental varnish composition, and method of use |
US5160737A (en) * | 1988-05-03 | 1992-11-03 | Perio Products Ltd. | Liquid polymer composition, and method of use |
US5165952A (en) * | 1989-01-18 | 1992-11-24 | Becton, Dickinson And Company | Anti-infective and antithrombogenic medical articles and method for their preparation |
US5525348A (en) * | 1989-11-02 | 1996-06-11 | Sts Biopolymers, Inc. | Coating compositions comprising pharmaceutical agents |
US5261896A (en) * | 1990-01-10 | 1993-11-16 | Rochester Medical Corporation | Sustained release bactericidal cannula |
US5217493A (en) * | 1992-03-11 | 1993-06-08 | Board Of Regents, The University Of Texas System | Antibacterial coated medical implants |
JPH0770478A (ja) * | 1993-09-03 | 1995-03-14 | Toyobo Co Ltd | 抗菌性組成物とそれを用いた抗菌性材料の製法 |
US5554147A (en) * | 1994-02-01 | 1996-09-10 | Caphco, Inc. | Compositions and devices for controlled release of active ingredients |
JP3087105B2 (ja) * | 1995-04-20 | 2000-09-11 | 敏 瀧川 | シリコンオイルとポリメタアクリル酸アルキルエステルよりなる塗剤 |
US5624704A (en) * | 1995-04-24 | 1997-04-29 | Baylor College Of Medicine | Antimicrobial impregnated catheters and other medical implants and method for impregnating catheters and other medical implants with an antimicrobial agent |
US5879697A (en) * | 1997-04-30 | 1999-03-09 | Schneider Usa Inc | Drug-releasing coatings for medical devices |
US6110483A (en) * | 1997-06-23 | 2000-08-29 | Sts Biopolymers, Inc. | Adherent, flexible hydrogel and medicated coatings |
JPH1121400A (ja) * | 1997-07-04 | 1999-01-26 | Otsuka Chem Co Ltd | 抗菌もしくは抗黴性樹脂組成物およびその用途 |
US6458341B1 (en) * | 1998-06-04 | 2002-10-01 | 3M Innovative Properties Company | Devices with coatings containing chlorhexidine gluconate, compositions and methods |
US6645483B2 (en) * | 1998-10-07 | 2003-11-11 | Sherwood Services Ag | Lubricious coating |
-
2002
- 2002-09-11 DE DE10242476A patent/DE10242476B4/de not_active Expired - Fee Related
-
2003
- 2003-08-27 CA CA2438346A patent/CA2438346C/en not_active Expired - Fee Related
- 2003-08-29 AT AT03019738T patent/ATE300319T1/de active
- 2003-08-29 PT PT03019738T patent/PT1398046E/pt unknown
- 2003-08-29 DE DE50300849T patent/DE50300849D1/de not_active Expired - Lifetime
- 2003-08-29 DK DK03019738T patent/DK1398046T3/da active
- 2003-08-29 EP EP03019738A patent/EP1398046B1/de not_active Expired - Lifetime
- 2003-08-29 ES ES03019738T patent/ES2242920T3/es not_active Expired - Lifetime
- 2003-09-03 AU AU2003244544A patent/AU2003244544B2/en not_active Ceased
- 2003-09-09 JP JP2003317448A patent/JP4528507B2/ja not_active Expired - Fee Related
- 2003-09-10 ZA ZA200307059A patent/ZA200307059B/xx unknown
- 2003-09-10 BR BR0303493-3A patent/BR0303493A/pt not_active IP Right Cessation
- 2003-09-11 CN CNA031589219A patent/CN1494925A/zh active Pending
- 2003-09-11 US US10/659,894 patent/US20040137065A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
ES2242920T3 (es) | 2005-11-16 |
EP1398046A1 (de) | 2004-03-17 |
CA2438346C (en) | 2010-11-09 |
DE50300849D1 (de) | 2005-09-01 |
DE10242476A1 (de) | 2004-03-25 |
CA2438346A1 (en) | 2004-03-11 |
ATE300319T1 (de) | 2005-08-15 |
DE10242476B4 (de) | 2006-10-26 |
ZA200307059B (en) | 2004-07-01 |
CN1494925A (zh) | 2004-05-12 |
AU2003244544A1 (en) | 2004-03-25 |
PT1398046E (pt) | 2005-10-31 |
AU2003244544B2 (en) | 2005-08-04 |
DK1398046T3 (da) | 2005-10-10 |
JP4528507B2 (ja) | 2010-08-18 |
JP2004097822A (ja) | 2004-04-02 |
EP1398046B1 (de) | 2005-07-27 |
US20040137065A1 (en) | 2004-07-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
B15K | Others concerning applications: alteration of classification |
Free format text: PARA: INT. CL. A61K 31/7036, 31/74; A61P 31/04 Ipc: A61K 31/7036 (2011.01), A61K 31/74 (2011.01), A61P |
|
B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 9A ANUIDADE. |
|
B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2166 DE 10/07/2012. |