BR0214954A - Pré-formulação para a produção de comprimidos de misturas de estrogênios conjugados naturais - Google Patents

Pré-formulação para a produção de comprimidos de misturas de estrogênios conjugados naturais

Info

Publication number
BR0214954A
BR0214954A BR0214954-0A BR0214954A BR0214954A BR 0214954 A BR0214954 A BR 0214954A BR 0214954 A BR0214954 A BR 0214954A BR 0214954 A BR0214954 A BR 0214954A
Authority
BR
Brazil
Prior art keywords
production
natural
preformulation
conjugated estrogen
preformulations
Prior art date
Application number
BR0214954-0A
Other languages
English (en)
Portuguese (pt)
Inventor
Bernd Thumbeck
Ingo Bonnacker
Martina Lerch
Original Assignee
Solvay Pharm Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Solvay Pharm Gmbh filed Critical Solvay Pharm Gmbh
Publication of BR0214954A publication Critical patent/BR0214954A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/167—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface
    • A61K9/1676—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface having a drug-free core with discrete complete coating layer containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/30—Oestrogens

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Endocrinology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Diabetes (AREA)
  • Reproductive Health (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
BR0214954-0A 2001-12-14 2002-12-12 Pré-formulação para a produção de comprimidos de misturas de estrogênios conjugados naturais BR0214954A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP01129840 2001-12-14
PCT/EP2002/014104 WO2003051337A1 (de) 2001-12-14 2002-12-12 Präformulierung für die tablettierung von natürlichen gemischen konjugierter oestrogene

Publications (1)

Publication Number Publication Date
BR0214954A true BR0214954A (pt) 2004-12-14

Family

ID=8179550

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0214954-0A BR0214954A (pt) 2001-12-14 2002-12-12 Pré-formulação para a produção de comprimidos de misturas de estrogênios conjugados naturais

Country Status (13)

Country Link
US (2) US8273728B2 (enExample)
EP (1) EP1458363B1 (enExample)
JP (1) JP4695838B2 (enExample)
CN (2) CN1298313C (enExample)
AR (1) AR037642A1 (enExample)
AU (1) AU2002358682B2 (enExample)
BR (1) BR0214954A (enExample)
CA (1) CA2470209A1 (enExample)
ES (1) ES2403218T3 (enExample)
MX (1) MXPA04005767A (enExample)
PL (1) PL205544B1 (enExample)
TW (1) TWI332400B (enExample)
WO (1) WO2003051337A1 (enExample)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9586335B2 (en) * 2010-01-27 2017-03-07 Sd3, Llc Blade guard with dust collection
TWI332400B (en) * 2001-12-14 2010-11-01 Solvay Pharm Gmbh Preformulation for the tableting of natural mixtures of conjugated estrogens
US8349819B2 (en) 2002-10-09 2013-01-08 Dr. Reddy's Laboratories New York, Inc. Steroid extraction process from urine sources
US6992075B2 (en) * 2003-04-04 2006-01-31 Barr Laboratories, Inc. C(14) estrogenic compounds
US8497258B2 (en) 2005-11-12 2013-07-30 The Regents Of The University Of California Viscous budesonide for the treatment of inflammatory diseases of the gastrointestinal tract
US20090232897A1 (en) * 2008-03-14 2009-09-17 Bijayananda Sahoo Pharmaceutical compositions comprising conjugated estrogens
EP2440210A4 (en) 2009-06-12 2014-01-29 Meritage Pharma Inc METHOD FOR THE TREATMENT OF STOMACH DARM DISEASES
US20120100211A1 (en) * 2009-07-16 2012-04-26 James Farina Material and process for incorporation of low dosage active pharmaceutical ingredients and use thereof
US9301920B2 (en) 2012-06-18 2016-04-05 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
EP2782584B1 (en) 2011-11-23 2021-06-09 TherapeuticsMD, Inc. Natural combination hormone replacement formulations and therapies
WO2013083674A1 (de) * 2011-12-08 2013-06-13 Hexal Ag Neue pharmazeutische statin-zusammensetzung
US20130338122A1 (en) 2012-06-18 2013-12-19 Therapeuticsmd, Inc. Transdermal hormone replacement therapies
US20150196640A1 (en) 2012-06-18 2015-07-16 Therapeuticsmd, Inc. Progesterone formulations having a desirable pk profile
US10806740B2 (en) 2012-06-18 2020-10-20 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
US10806697B2 (en) 2012-12-21 2020-10-20 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10568891B2 (en) 2012-12-21 2020-02-25 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10471072B2 (en) 2012-12-21 2019-11-12 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US9180091B2 (en) 2012-12-21 2015-11-10 Therapeuticsmd, Inc. Soluble estradiol capsule for vaginal insertion
US10537581B2 (en) 2012-12-21 2020-01-21 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US11246875B2 (en) 2012-12-21 2022-02-15 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US11266661B2 (en) 2012-12-21 2022-03-08 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
AR100562A1 (es) 2014-05-22 2016-10-12 Therapeuticsmd Inc Composición farmacéutica de estradiol y progesterona para terapia de reemplazo hormonal
US10328087B2 (en) 2015-07-23 2019-06-25 Therapeuticsmd, Inc. Formulations for solubilizing hormones
WO2017173044A1 (en) 2016-04-01 2017-10-05 Therapeuticsmd Inc. Steroid hormone compositions in medium chain oils
KR20180126582A (ko) 2016-04-01 2018-11-27 쎄러퓨틱스엠디, 인코퍼레이티드 스테로이드 호르몬 약제학적 조성물
US11633405B2 (en) 2020-02-07 2023-04-25 Therapeuticsmd, Inc. Steroid hormone pharmaceutical formulations
US20210246928A1 (en) * 2020-02-11 2021-08-12 Carl Chasse Fastener having improved wobble control, fastening system including the same, and method of forming the same

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3487152A (en) * 1967-02-07 1969-12-30 Hoffmann La Roche Tablets containing 7 - chloro - 2 - methylamino - 5 - phenyl - 3h - 1,4 - benzodiazepine-4-oxide and conjugated estrogenic substances
US4154820A (en) 1976-02-23 1979-05-15 Akzona Incorporated Compositions containing alkali metal sulfate salts of conjugated estrogens and antioxidants as stabilizers
DE3535536A1 (de) 1985-10-04 1987-04-09 Lentia Gmbh Verfahren zum gleichzeitigen trocknen und granulieren von extraktstoffen aus enteiweisstem kaelberblut
EP0322020A1 (en) * 1987-12-22 1989-06-28 Akzo N.V. Pharmaceutical dosage unit for treating climacteric complaints and osteoporosis
WO1997004752A1 (en) * 1995-07-26 1997-02-13 Duramed Pharmaceuticals, Inc. Pharmaceutical compositions of conjugated estrogens and methods for their use
PL185919B1 (pl) 1996-08-30 2003-08-29 Solvay Pharm Gmbh Sposób otrzymywania estrogenów z moczu klaczySposób otrzymywania estrogenów z moczu klaczy
SK281367B6 (sk) 1996-08-30 2001-02-12 Solvay Pharmaceuticals Gmbh Spôsob získavania estrogénov z moču kobýl
US6200289B1 (en) 1998-04-10 2001-03-13 Milestone Scientific, Inc. Pressure/force computer controlled drug delivery system and the like
JP2000156938A (ja) 1998-11-19 2000-06-06 Hokuto Denko Kk 電池の充放電試験装置
TWI332400B (en) * 2001-12-14 2010-11-01 Solvay Pharm Gmbh Preformulation for the tableting of natural mixtures of conjugated estrogens

Also Published As

Publication number Publication date
EP1458363A1 (de) 2004-09-22
CN1298313C (zh) 2007-02-07
WO2003051337A1 (de) 2003-06-26
HK1075007A1 (en) 2005-12-02
EP1458363B1 (de) 2013-01-16
JP2005516923A (ja) 2005-06-09
MXPA04005767A (es) 2004-09-10
JP4695838B2 (ja) 2011-06-08
CA2470209A1 (en) 2003-06-26
CN100502839C (zh) 2009-06-24
CN1977862A (zh) 2007-06-13
US20120237666A1 (en) 2012-09-20
US8273728B2 (en) 2012-09-25
AR037642A1 (es) 2004-11-17
PL368730A1 (en) 2005-04-04
PL205544B1 (pl) 2010-04-30
TWI332400B (en) 2010-11-01
ES2403218T3 (es) 2013-05-16
TW200408400A (en) 2004-06-01
HK1104220A1 (zh) 2008-01-11
AU2002358682A1 (en) 2003-06-30
US8329679B2 (en) 2012-12-11
CN1607944A (zh) 2005-04-20
US20050009800A1 (en) 2005-01-13
AU2002358682B2 (en) 2009-03-26

Similar Documents

Publication Publication Date Title
PT1339675E (pt) Compostos bisarilo orto, meta-substituidos, processo para a sua preparacao, sua utilizacao como medicamentos e composicoes farmaceuticas que os contem
AR066982A2 (es) Compuestos heteroaromaticos sustituidos como inhibidoress tirosin quinasa, composiciones farmaceuticas que los contiene y su uso en la preparacion de medicamentos
MXPA04005767A (es) Formacion previa para hacer tabletas de mezclas naturales de estrogenos conjugados.
ES2081349T3 (es) Rotogranulaciones y recubrimientos para enmascarar el sabor para la preparacion de comprimidos farmaceuticos de mascar.
BR0109198A (pt) Emplastro com filtro ultravioleta
ES2181417T3 (es) Formulacion de capsulas o tabletas de efavirenz de disolucion rapida usando super-desintegrantes.
BR0206164A (pt) Partìculas cristalinas de oxalato de escitalopram, método para a produção de partìculas cristalinas de oxalato de escitalopram, e, forma de dosagem unitária sólida
AU2002235930A1 (en) A process for the manufacture of a herbal composition comprising a matrine
SV1999000049A (es) Nuevas dihidropirimidinas 2 heterociclicamente sustituidas ref. lea 32793-sv
BRPI0206509B8 (pt) processo para formular, para administração parenteral, um análogo de epotilona, preparação farmacêutica, processo para formar uma composição farmacêutica para administração parental, composição farmacêutica e uso de um análogo de epotilona na preparação de uma composição farmacêutica para o tratamento de câncer
Chen et al. Mechanistic studies of the transport of peimine in the Caco-2 cell model
AR011080A1 (es) Composicion en polvo seco, proceso para su preparacion y uso de dicha composicion para la fabricacion del medicamento
PT1222163E (pt) 1,1-bifenil-2-carboxamidas substituidas na posicao 2 processo para a sua preparacao, sua utilizacao como medicamento, bem como preparacoes farmaceuticas contendo estas
BR0012258A (pt) Processo para a preparação de preparados farmacêuticos sólidos, que se decompõem rapidamente
BR0211198A (pt) Composições farmacêuticas e seu uso
BR0311940A (pt) Difenilazetidinonas substituìdas no anel, processo para produção das mesmas, medicamentos que contêm esses compostos e uso dos mesmos
AR025052A1 (es) Derivados de 2-dialquilaminoalquilbifenilo sustituidos, procedimiento para su preparacion, medicamentos que contienen estos compuestos y el uso de estoscompuestos para la preparacion de medicamentos.
BRPI0607583A2 (pt) derivados de piridin-2-carboxamida como antagonistas mglur5, método para sua preparação, medicamento contendo os mesmos, bem como uso relacionado aos referidos compostos
BR0307461A (pt) Derivados de quinazolinona e seu uso como agonistas de cb
ES2131318T3 (es) Pelets.
PT1122254E (pt) Derivados de 4-sulfonamidas piperidina, processo para a sua preparacao e as composicoes farmaceuticas que os contem
CL2004001068A1 (es) Compuestos derivados de 2,3,4,5-tetrahidrobenzo[f][1,4]oxazepina; procedimientos de preparacion; composicion farmaceutica que los contiene y su uso en la elaboracion de un medicamento util para el tratamiento de la enfermedad de alzheimer.
TR200003303T2 (tr) Astıma, alerjiye, iltihaplanmaya karşı, bağışıklık düzenleyici ve sinirsel koruyucu etkiye sahip yeni 1,5- ve 3-O-ikameli 1H-indazoller, bunların hazırlanması ve tıbbi maddeler olarak kullanımları.
BRPI0518789A2 (pt) formulaÇço farmacÊutica, processo para preparar uma formulaÇço farmacÊutica, produto, e, cÁpsula ou tablete
PT1118610E (pt) Novos derivados de benzeno-sulfonamida processo para a sua preparacao e as composicoes farmaceuticas que os contem

Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B15K Others concerning applications: alteration of classification

Free format text: PARA.INT.CI.A61K 9/16, A61P 15/12

Ipc: A61K 9/16 (2011.01), A61P 15/12 (2011.01)

B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B25D Requested change of name of applicant approved

Owner name: ABBOTT PRODUCTS GMBH (DE)

B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]

Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI

B09A Decision: intention to grant [chapter 9.1 patent gazette]
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 13A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2343 DE 01-12-2015 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.