BR0214884A - Derivados de 7-amino-benzotiazol como ligantes do receptor de adenosina - Google Patents
Derivados de 7-amino-benzotiazol como ligantes do receptor de adenosinaInfo
- Publication number
- BR0214884A BR0214884A BR0214884-6A BR0214884A BR0214884A BR 0214884 A BR0214884 A BR 0214884A BR 0214884 A BR0214884 A BR 0214884A BR 0214884 A BR0214884 A BR 0214884A
- Authority
- BR
- Brazil
- Prior art keywords
- amino
- adenosine receptor
- receptor ligands
- benzothiazole derivatives
- adenosine
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
- C07D277/62—Benzothiazoles
- C07D277/68—Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C07D277/82—Nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/34—Tobacco-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/08—Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/08—Bridged systems
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Psychiatry (AREA)
- Addiction (AREA)
- Pulmonology (AREA)
- Pain & Pain Management (AREA)
- Cardiology (AREA)
- Hospice & Palliative Care (AREA)
- Psychology (AREA)
- Heart & Thoracic Surgery (AREA)
- Immunology (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Anesthesiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
"DERIVADOS DE 7-AMINO-BENZOTIAZOL COMO LIGANTES DO RECEPTOR DE ADENOSINA". A presente invenção refere-se a compostos de fórmula geral (I): Foi descoberto que os compostos de fórmula geral (1) são ligantes do receptor de adenosina. Especificamente, os compostos da presente invenção apresentam uma satisfatória afinidade ao receptor A~ 2A~ de adenosina, sendo, portanto, de utilidade no tratamento de doenças correlacionadas a esse receptor.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP01129272 | 2001-12-12 | ||
PCT/EP2002/013770 WO2003053946A1 (en) | 2001-12-12 | 2002-12-05 | 7-amino-benzothiazole derivatives as adenosine receptor ligands |
Publications (1)
Publication Number | Publication Date |
---|---|
BR0214884A true BR0214884A (pt) | 2004-11-23 |
Family
ID=8179486
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR0214884-6A BR0214884A (pt) | 2001-12-12 | 2002-12-05 | Derivados de 7-amino-benzotiazol como ligantes do receptor de adenosina |
Country Status (18)
Country | Link |
---|---|
US (1) | US6713499B2 (pt) |
EP (1) | EP1456188A1 (pt) |
JP (1) | JP4244189B2 (pt) |
KR (1) | KR100581705B1 (pt) |
CN (1) | CN1305862C (pt) |
AR (1) | AR037767A1 (pt) |
AU (1) | AU2002360960B8 (pt) |
BR (1) | BR0214884A (pt) |
CA (1) | CA2469884A1 (pt) |
GT (1) | GT200200269A (pt) |
MX (1) | MXPA04005633A (pt) |
PA (1) | PA8561001A1 (pt) |
PE (1) | PE20030761A1 (pt) |
PL (1) | PL373953A1 (pt) |
RU (1) | RU2299203C2 (pt) |
TW (1) | TW200409763A (pt) |
UY (1) | UY27580A1 (pt) |
WO (1) | WO2003053946A1 (pt) |
Families Citing this family (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6734179B2 (en) * | 2001-12-12 | 2004-05-11 | Hoffmann-La Roche Inc. | Benzothiazoles |
RU2348622C2 (ru) * | 2003-05-21 | 2009-03-10 | Ф.Хоффманн-Ля Рош Аг | Производные бензотиазола и их применение при лечении заболеваний, связанных с аденозиновыми а2а-рецепторами |
MXPA06002943A (es) | 2003-09-19 | 2006-05-31 | Hoffmann La Roche | Derivados de tiazolopiridina como ligandos del receptor de adenosina. |
TW200524887A (en) * | 2003-10-27 | 2005-08-01 | Lundbeck & Co As H | N-thiazol-2-yl-benzamide derivatives |
WO2005044793A2 (en) * | 2003-10-31 | 2005-05-19 | Takeda Pharmaceutical Company Limited | Nitrogen-containing fused heterocyclic compounds |
KR100834179B1 (ko) * | 2004-05-24 | 2008-05-30 | 에프. 호프만-라 로슈 아게 | 4-하이드록시-4-메틸-피페리딘-1-카복실산(4-메톡시-7-모폴린-4-일-벤조티아졸-2-일)-아마이드 |
MXPA06013417A (es) * | 2004-05-24 | 2007-01-23 | Hoffmann La Roche | (4-metoxi-7-morfolin-4-il-benzotiazol-2-il) amida del acido 4-hidroxi-4-metil-piperidin-1-carboxilico. |
EP1773795A1 (en) * | 2004-07-22 | 2007-04-18 | F.Hoffmann-La Roche Ag | Substituted benzothiazoles |
BRPI0513511A (pt) * | 2004-07-22 | 2008-05-06 | Hoffmann La Roche | derivados de benzotiazol |
EP1794157B1 (en) | 2004-09-22 | 2014-02-26 | H. Lundbeck A/S | 2-acylaminothiazole derivatives |
ES2644450T3 (es) * | 2004-12-31 | 2017-11-29 | Dr. Reddy's Laboratories Ltd. | Nuevos derivados de bencilamina como inhibidores de CETP |
US8604055B2 (en) * | 2004-12-31 | 2013-12-10 | Dr. Reddy's Laboratories Ltd. | Substituted benzylamino quinolines as cholesterol ester-transfer protein inhibitors |
AU2006226669B2 (en) | 2005-03-23 | 2011-12-08 | F. Hoffmann-La Roche Ag | Acetylenyl-pyrazolo-pvrimidine derivatives as mGluR2 antagonists |
US7674912B2 (en) | 2005-04-25 | 2010-03-09 | H. Lundbeck A/S | Pro-drugs of N-thiazol-2-yl-benzamide derivatives |
AU2006298829B2 (en) | 2005-09-27 | 2011-03-03 | F. Hoffmann-La Roche Ag | Oxadiazolyl pyrazolo-pyrimidines as mGluR2 antagonists |
DE602007009221D1 (de) | 2006-05-18 | 2010-10-28 | Hoffmann La Roche | Thiazolopyramidin/pyridinharnstoffderivate als antagonisten am adenosin-a2b-rezeptor |
US8168785B2 (en) | 2009-06-17 | 2012-05-01 | Biotie Therapies, Inc. | Benzothiazole derivatives |
RU2448100C1 (ru) * | 2010-09-24 | 2012-04-20 | Татьяна Николаевна Иванова | Производные 2-аминобензотиазола, обладающие противогипоксической активностью, и способ их использования |
DE102011005232A1 (de) | 2011-03-08 | 2012-09-13 | AristoCon GmbH & Co. KG | Adenosin und seine Derivate zur Verwendung in der Schmerztherapie |
WO2013024358A2 (en) | 2011-08-18 | 2013-02-21 | Dr. Reddy's Laboratories Ltd. | Substituted heterocyclic amine compounds as cholestryl ester-transfer protein (cetp) inhibitors |
KR101803866B1 (ko) | 2011-09-27 | 2017-12-04 | 닥터 레디스 레보러터리즈 리미티드 | 동맥경화증 치료에 유용한 콜레스테릴 에스테르-전달 단백질(cetp) 억제제로서 5-벤질아미노메틸-6-아미노피라졸로[3,4-b]피리딘 유도체 |
WO2017136375A1 (en) * | 2016-02-05 | 2017-08-10 | Concert Pharmaceuticals, Inc. | Deuterated tozadenant |
KR20200035439A (ko) * | 2017-08-01 | 2020-04-03 | 메르크 파텐트 게엠베하 | 아데노신 수용체 길항제로서의 티아졸로피리딘 유도체 |
DE102019110904B4 (de) | 2019-04-26 | 2022-01-20 | Helmholtz-Zentrum Dresden - Rossendorf E. V. | N-(4-methoxy-7-morpholinobenzo[d]thiazol-2-yl)-acetamid-Derivate und deren Verwendung |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1117663A2 (en) | 1998-09-30 | 2001-07-25 | Neurogen Corporation | 2-piperazino alkylamino benzoazole derivatives: dopamine receptor subtype specific ligands |
NZ522928A (en) * | 2000-06-21 | 2005-05-27 | F | Benzothiazole derivatives |
-
2002
- 2002-12-02 US US10/307,702 patent/US6713499B2/en not_active Expired - Fee Related
- 2002-12-05 RU RU2004121688/04A patent/RU2299203C2/ru not_active IP Right Cessation
- 2002-12-05 JP JP2003554662A patent/JP4244189B2/ja not_active Expired - Fee Related
- 2002-12-05 MX MXPA04005633A patent/MXPA04005633A/es active IP Right Grant
- 2002-12-05 CA CA002469884A patent/CA2469884A1/en not_active Abandoned
- 2002-12-05 WO PCT/EP2002/013770 patent/WO2003053946A1/en active Application Filing
- 2002-12-05 BR BR0214884-6A patent/BR0214884A/pt not_active Application Discontinuation
- 2002-12-05 CN CNB028250095A patent/CN1305862C/zh not_active Expired - Fee Related
- 2002-12-05 PL PL02373953A patent/PL373953A1/xx not_active Application Discontinuation
- 2002-12-05 EP EP02795100A patent/EP1456188A1/en not_active Withdrawn
- 2002-12-05 AU AU2002360960A patent/AU2002360960B8/en not_active Ceased
- 2002-12-05 KR KR1020047008929A patent/KR100581705B1/ko not_active IP Right Cessation
- 2002-12-09 TW TW091135543A patent/TW200409763A/zh unknown
- 2002-12-10 AR ARP020104772A patent/AR037767A1/es unknown
- 2002-12-10 PA PA20028561001A patent/PA8561001A1/es unknown
- 2002-12-11 GT GT200200269A patent/GT200200269A/es unknown
- 2002-12-11 PE PE2002001192A patent/PE20030761A1/es not_active Application Discontinuation
- 2002-12-11 UY UY27580A patent/UY27580A1/es not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
MXPA04005633A (es) | 2004-12-06 |
JP2005526706A (ja) | 2005-09-08 |
PL373953A1 (en) | 2005-09-19 |
CA2469884A1 (en) | 2003-07-03 |
CN1305862C (zh) | 2007-03-21 |
AU2002360960A1 (en) | 2003-07-09 |
JP4244189B2 (ja) | 2009-03-25 |
WO2003053946A1 (en) | 2003-07-03 |
KR20040073472A (ko) | 2004-08-19 |
GT200200269A (es) | 2003-07-30 |
CN1604897A (zh) | 2005-04-06 |
US20030153566A1 (en) | 2003-08-14 |
AU2002360960B2 (en) | 2008-03-06 |
PA8561001A1 (es) | 2003-12-10 |
EP1456188A1 (en) | 2004-09-15 |
KR100581705B1 (ko) | 2006-05-22 |
AR037767A1 (es) | 2004-12-01 |
UY27580A1 (es) | 2003-06-30 |
AU2002360960B8 (en) | 2008-04-10 |
US6713499B2 (en) | 2004-03-30 |
PE20030761A1 (es) | 2003-09-05 |
TW200409763A (en) | 2004-06-16 |
RU2004121688A (ru) | 2005-05-27 |
RU2299203C2 (ru) | 2007-05-20 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
BR0214884A (pt) | Derivados de 7-amino-benzotiazol como ligantes do receptor de adenosina | |
ATE263157T1 (de) | Nematizide trifluorbutene | |
TW200510325A (en) | 2-acylamino-4-phenylthiazole derivatives, preparation thereof and therapeutic application thereof | |
BRPI0510273A (pt) | derivados de tetraazabenzo[e]azuleno e análogos destes | |
BRPI0417543A (pt) | quinolinas úteis no tratamento de doença cardiovascular | |
BRPI0412347A (pt) | 2-aminofenil-4-fenilpiridinas como inibidores de quinase | |
BR0308261A (pt) | Métodos extrativos para puruficação de sucralose | |
BR0116047A (pt) | Imidazoquinolinas substituìdas de éter heterocìclico | |
BR0309355A (pt) | 2-(2,6-diclorofenil)-diarilimidazóis | |
NO20055649L (no) | Substituert dihydrokinazolin med antiviale egenskaper | |
BRPI0512352A (pt) | 3-aminociclopentanocarboxamidas como moduladores de receptores de quimiocinas | |
BR0318278A (pt) | compostos de éter aminocicloexìlico e usos dos mesmo | |
BR0308211A (pt) | Cumarinas úteis como biomarcadores | |
BR0114252A (pt) | Derivados de nitrosodifenilamina | |
TW200740814A (en) | Compounds | |
MXPA04000886A (es) | Derivados de triazolil-imidazopiridina y triazolilpurinas empledos como ligandos del receptor de adenosina a2a y su uso como medicamentos. | |
ES2243579T3 (es) | Derivados de pirazolopirideno. | |
SG162753A1 (en) | Methods of treating cancer and other conditions or disease states using lfmau and ldt | |
NO20043016L (no) | 6-aminomorfinan-derivater, fremgangsmate for fremstilling og anvendelse derav | |
BR0308419A (pt) | Derivados de azetidina como antagonistas do receptor ccr-3 | |
BRPI0412843A (pt) | lactamas substituìdas e uso das mesmas como agentes anticáncer | |
BR0309753A (pt) | Processo para a preparação de derivados de 6-alquilideno penem | |
TW200738611A (en) | 9-Chloro-15-deoxyprostaglandin derivatives, process for their preparation and their use as medicaments | |
BRPI0108990B8 (pt) | processo para preparação de derivados de pirimidona com atividade antifungos | |
BR0007982A (pt) | Processo para a preparação de um composto, e,composto |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
B11E | Dismissal acc. art. 34 of ipl - requirements for examination incomplete | ||
B11T | Dismissal of application maintained [chapter 11.20 patent gazette] |