BR0213741A - composto e composição antiretrovirais - Google Patents
composto e composição antiretroviraisInfo
- Publication number
- BR0213741A BR0213741A BRPI0213741-0A BR0213741A BR0213741A BR 0213741 A BR0213741 A BR 0213741A BR 0213741 A BR0213741 A BR 0213741A BR 0213741 A BR0213741 A BR 0213741A
- Authority
- BR
- Brazil
- Prior art keywords
- composition
- hiv
- antiretroviral compound
- compound
- certain
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/70—Sulfur atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/70—Sulfur atoms
- C07D213/71—Sulfur atoms to which a second hetero atom is attached
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/89—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to the ring nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/36—Sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Virology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Molecular Biology (AREA)
- AIDS & HIV (AREA)
- Tropical Medicine & Parasitology (AREA)
- Pyridine Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Quinoline Compounds (AREA)
Abstract
"COMPOSTO E COMPOSIçãO ANTIRETROVIRAIS" Certos derivados de piridina e quinolina que inibem a replicação dos retrovírus HIV-1, HIV-2 e citomegalovírus humano (HCMV) são apresentados. Composições farmacêuticas úteis em métodos de tratar e inibir certas infecções por retrovírus são descritas.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10/021,202 US6498254B1 (en) | 2001-10-29 | 2001-10-29 | Antiretroviral compounds and compositions |
PCT/US2002/029573 WO2003037866A1 (en) | 2001-10-29 | 2002-09-17 | Antiretroviral pyridine and quinoline derivatives |
Publications (1)
Publication Number | Publication Date |
---|---|
BR0213741A true BR0213741A (pt) | 2006-05-23 |
Family
ID=21802920
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0213741-0A BR0213741A (pt) | 2001-10-29 | 2002-09-17 | composto e composição antiretrovirais |
Country Status (7)
Country | Link |
---|---|
US (1) | US6498254B1 (pt) |
JP (1) | JP2005509644A (pt) |
CN (1) | CN1291976C (pt) |
BR (1) | BR0213741A (pt) |
CA (1) | CA2465305A1 (pt) |
MX (1) | MXPA04004061A (pt) |
WO (1) | WO2003037866A1 (pt) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7064139B2 (en) * | 2001-10-29 | 2006-06-20 | Uniroyal Chemical Company, Inc. | Method for treating retroviral infections |
CN102952069B (zh) * | 2011-08-19 | 2014-12-17 | 中国科学技术大学 | 一种化合物及其制备方法和应用 |
EP2757161A1 (en) | 2013-01-17 | 2014-07-23 | Splicos | miRNA-124 as a biomarker of viral infection |
EP2974729A1 (en) | 2014-07-17 | 2016-01-20 | Abivax | Quinoline derivatives for use in the treatment of inflammatory diseases |
CN106674099A (zh) * | 2016-12-22 | 2017-05-17 | 江苏燎原环保科技股份有限公司 | 一种二[2‑(n‑氧化物‑吡啶基‑2‑硫基)乙基]胺的制备方法 |
CN106674100A (zh) * | 2016-12-22 | 2017-05-17 | 江苏燎原环保科技股份有限公司 | 一种三[2‑(n‑氧化物‑吡啶基‑2‑硫基)乙基]胺的制备方法 |
EP3669873A1 (en) | 2018-12-20 | 2020-06-24 | Abivax | Quinoline derivatives for use ine the traeatment of inflammation diseases |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5268389A (en) * | 1989-10-16 | 1993-12-07 | Uniroyal Chemical Company, Inc. | Thiocarboxylate ester compounds compositions containing the same |
WO1992006683A1 (en) * | 1990-10-22 | 1992-04-30 | Research Corporation Technologies, Inc. | Aryl and heteroaryl compounds having anti-retrovirus activity |
EP0555770A1 (de) * | 1992-02-14 | 1993-08-18 | Hoechst Schering AgrEvo GmbH | N-Heteroaryl-N'-(pyrid-2-yl-sulfonyl)-harnstoffe, Verfahren zu ihrer Herstellung und ihre Verwendung als Herbizide und Pflanzenwachstumsregulatoren |
WO1995029897A1 (en) * | 1994-04-29 | 1995-11-09 | G.D. Searle & Co. | METHOD OF USING (H+/K+) ATPase INHIBITORS AS ANTIVIRAL AGENTS |
FR2737496B1 (fr) * | 1995-07-31 | 1997-12-19 | Centre Nat Rech Scient | 4-aryl-thio-pyridin-2(1h)-ones, medicaments les contenant et leurs utilisations dans le traitement de maladies liees aux vih 1 et 2 |
US5696151A (en) * | 1995-11-30 | 1997-12-09 | Uniroyal Chemical Company, Inc. | Compounds useful for the inhibition of the replication of HIV-1 and HIV-1 mutants |
GB9930061D0 (en) * | 1999-12-20 | 2000-02-09 | Glaxo Group Ltd | Quinolone compounds for use in treating viral infections |
-
2001
- 2001-10-29 US US10/021,202 patent/US6498254B1/en not_active Expired - Fee Related
-
2002
- 2002-09-17 MX MXPA04004061A patent/MXPA04004061A/es active IP Right Grant
- 2002-09-17 CA CA002465305A patent/CA2465305A1/en not_active Abandoned
- 2002-09-17 CN CNB028232941A patent/CN1291976C/zh not_active Expired - Fee Related
- 2002-09-17 BR BRPI0213741-0A patent/BR0213741A/pt not_active IP Right Cessation
- 2002-09-17 JP JP2003540148A patent/JP2005509644A/ja active Pending
- 2002-09-17 WO PCT/US2002/029573 patent/WO2003037866A1/en active Application Filing
Also Published As
Publication number | Publication date |
---|---|
WO2003037866A1 (en) | 2003-05-08 |
JP2005509644A (ja) | 2005-04-14 |
CA2465305A1 (en) | 2003-05-08 |
CN1291976C (zh) | 2006-12-27 |
CN1592741A (zh) | 2005-03-09 |
MXPA04004061A (es) | 2004-07-08 |
US6498254B1 (en) | 2002-12-24 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
EE03969B1 (et) | (Metüülsulfonüül)fenüül-2-(5H)-furanoonid, nende kasutamine ja farmatseutilised kompositsioonid | |
BRPI0507628A (pt) | composto ou sal farmaceuticamente aceitável do mesmo, método de tratamento de uma infecção viral em um ser humano, uso de um composto composição farmacêutica, e, processo para a preparação de um composto | |
ATE184594T1 (de) | Sulfonamidderivate als aspartylprotease- inhibitoren | |
TR199903053T2 (xx) | Benzimidazol t�revleri. | |
BR9909730A (pt) | Dihidropirimidinas | |
ATE245641T1 (de) | Antivirale pyrimidinderivate | |
BR9607543A (pt) | Inibidores de protease retroviral sulfonamida hidroxietilamino de bis-amino ácido | |
BG102048A (en) | Tetrahydrofuran-containing sulphonamides as aspartylprotease inhibitors | |
BR9607638A (pt) | Inibidores de protease retrovirais de hidroxietilamino sulfonamida de aminoácido | |
DK0951473T3 (da) | Cyclosporinderivat, fremstilling af dette og farmaceutiske præparater indeholdende dette | |
PT1052250E (pt) | Inibidores de protease retroviral sulfonilalcanoilamino hidroxietilamino sulfonamidas | |
HUP9904092A2 (hu) | Gyógyszerkészítmény HIV és rák kezelésére valamint eljárás előállítására | |
BR9607625A (pt) | Inibidores de protease retroviral sulfonamida hidroxietilamino de aminoácido heterociclocarbonila | |
DK1401826T3 (da) | Pyrazolderivater som inhibitorer for HIV-revers transcriptase | |
BR0213741A (pt) | composto e composição antiretrovirais | |
DK1053012T3 (da) | Farmaceutiske sammensætninger omfattende PEG-asparaginase til behandling af HIV-infektioner | |
ATE299027T1 (de) | Verwendung von übersulfatierten polysacchariden als hiv-hemmer | |
NO20020914L (no) | Alkoksy-substituerte benzimidazolforbindelser, preparater inneholdende slike samt anvendelser derav | |
ATE271859T1 (de) | Diphenyl ketoaldehyde-derivate mit wirkung gegen hiv | |
ATE282430T1 (de) | Eisenchelator enthaltende antivirale pharmazeutische zusammensetzungen | |
DE69426574D1 (de) | Makrocyclische difluorostatonderivate als antivirale mittel | |
TR199902508T2 (xx) | HIV proteaz inhibit�rleri. | |
UA31078A (uk) | Інгібітор вірусу імунодефіциту людини ( даримід ) |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
B08F | Application fees: application dismissed [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 8A ANUIDADE(S). |
|
B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2108 DE 31/05/2011. |