BR0209144A - Composição associadas ao fator de crescimento de fibroblasto humano - Google Patents
Composição associadas ao fator de crescimento de fibroblasto humanoInfo
- Publication number
- BR0209144A BR0209144A BR0209144-5A BR0209144A BR0209144A BR 0209144 A BR0209144 A BR 0209144A BR 0209144 A BR0209144 A BR 0209144A BR 0209144 A BR0209144 A BR 0209144A
- Authority
- BR
- Brazil
- Prior art keywords
- growth factor
- fibroblast growth
- human fibroblast
- composition associated
- methods
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 3
- 102000018233 Fibroblast Growth Factor Human genes 0.000 title abstract 2
- 108050007372 Fibroblast Growth Factor Proteins 0.000 title abstract 2
- 229940126864 fibroblast growth factor Drugs 0.000 title abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 2
- 102100024802 Fibroblast growth factor 23 Human genes 0.000 abstract 1
- 101001051973 Homo sapiens Fibroblast growth factor 23 Proteins 0.000 abstract 1
- 229910019142 PO4 Inorganic materials 0.000 abstract 1
- 239000000556 agonist Substances 0.000 abstract 1
- 239000005557 antagonist Substances 0.000 abstract 1
- 230000006378 damage Effects 0.000 abstract 1
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 abstract 1
- 239000010452 phosphate Substances 0.000 abstract 1
- 229920001184 polypeptide Polymers 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/50—Fibroblast growth factor [FGF]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Toxicology (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Hematology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
"COMPOSIçõES ASSOCIADAS AO FATOR DE CRESCIMENTO DE FIBROBLASTO HUMANO". A presente invenção refere-se a um polipeptídeo de FGF23, métodos e composições para produzir esse peptídeo, e métodos para usar o polipeptídeo, e agonistas e antagonistas do mesmo para tratar distúrbios de destruição de fosfato.
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US28661401P | 2001-04-26 | 2001-04-26 | |
US28818701P | 2001-05-01 | 2001-05-01 | |
US29342001P | 2001-05-24 | 2001-05-24 | |
PCT/EP2002/004660 WO2002088358A2 (en) | 2001-04-26 | 2002-04-26 | Human fibroblast growth factor-related compositions |
Publications (1)
Publication Number | Publication Date |
---|---|
BR0209144A true BR0209144A (pt) | 2004-06-08 |
Family
ID=27403632
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR0209144-5A BR0209144A (pt) | 2001-04-26 | 2002-04-26 | Composição associadas ao fator de crescimento de fibroblasto humano |
Country Status (8)
Country | Link |
---|---|
US (1) | US20040171825A1 (pt) |
EP (1) | EP1381683A2 (pt) |
JP (1) | JP2004527253A (pt) |
CN (1) | CN1602355A (pt) |
AU (1) | AU2002302581A1 (pt) |
BR (1) | BR0209144A (pt) |
CA (1) | CA2443719A1 (pt) |
WO (1) | WO2002088358A2 (pt) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TWI224620B (en) * | 2000-08-11 | 2004-12-01 | Kirin Brewery | Polypeptides controlling phosphoric acid metabolism, calcium metabolism, calcification and vitamin D metabolism and DNAS encoding the same |
EP1466925B1 (en) | 2001-12-28 | 2009-09-02 | Kyowa Hakko Kirin Co., Ltd. | Antibodies against fibroblast growth factor 23 |
WO2005045044A2 (en) * | 2003-11-07 | 2005-05-19 | Novartis Ag | Use of fibroblast growth factor fragments |
US7883705B2 (en) * | 2007-02-14 | 2011-02-08 | Kyowa Hakko Kirin Co., Ltd. | Anti FGF23 antibody and a pharmaceutical composition comprising the same |
US8420088B2 (en) * | 2008-01-28 | 2013-04-16 | Novartis Ag | Methods and compositions using FGF23 fusion polypeptides |
EA201791238A1 (ru) | 2014-12-04 | 2018-02-28 | Новартис Аг | Способы и композиции, в которых используются варианты полипептидов klotho |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2398603A1 (en) * | 2000-02-15 | 2001-08-23 | Amgen, Inc. | Fibroblast growth factor-23 molecules and uses thereof |
EP1261638A2 (en) * | 2000-03-08 | 2002-12-04 | Chiron Corporation | Human fgf-23 gene and gene expression products |
AU2001245535A1 (en) * | 2000-03-08 | 2001-09-17 | Chiron Corporation | Human fgf-23 gene and gene expression products |
KR20090036151A (ko) * | 2000-07-19 | 2009-04-13 | 인디애나 유니버시티 리서치 앤드 테크놀로지 코포레이션 | 신규 섬유아세포 성장 인자 (fgf23) 및 그의 이용 방법 |
-
2002
- 2002-04-26 CA CA002443719A patent/CA2443719A1/en not_active Abandoned
- 2002-04-26 BR BR0209144-5A patent/BR0209144A/pt not_active IP Right Cessation
- 2002-04-26 JP JP2002585639A patent/JP2004527253A/ja active Pending
- 2002-04-26 US US10/475,663 patent/US20040171825A1/en not_active Abandoned
- 2002-04-26 WO PCT/EP2002/004660 patent/WO2002088358A2/en not_active Application Discontinuation
- 2002-04-26 EP EP02730215A patent/EP1381683A2/en not_active Withdrawn
- 2002-04-26 AU AU2002302581A patent/AU2002302581A1/en not_active Abandoned
- 2002-04-26 CN CNA028088778A patent/CN1602355A/zh active Pending
Also Published As
Publication number | Publication date |
---|---|
WO2002088358A2 (en) | 2002-11-07 |
WO2002088358A3 (en) | 2003-07-24 |
CA2443719A1 (en) | 2002-11-07 |
US20040171825A1 (en) | 2004-09-02 |
AU2002302581A1 (en) | 2002-11-11 |
JP2004527253A (ja) | 2004-09-09 |
EP1381683A2 (en) | 2004-01-21 |
CN1602355A (zh) | 2005-03-30 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B25A | Requested transfer of rights approved |
Owner name: GENOVA LTD. (BM) Free format text: TRANSFERIDO DE: GENEPROT, INC. |
|
B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE 7A. E 8A. ANUIDADES. |
|
B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2060 DE 29/06/2010. |