BR0116672A - Pharmaceutically acceptable salt of a compound, compound, pharmaceutical composition, use of a pharmaceutically acceptable salt, and process for preparing a compound. - Google Patents

Pharmaceutically acceptable salt of a compound, compound, pharmaceutical composition, use of a pharmaceutically acceptable salt, and process for preparing a compound.

Info

Publication number
BR0116672A
BR0116672A BR0116672-7A BR0116672A BR0116672A BR 0116672 A BR0116672 A BR 0116672A BR 0116672 A BR0116672 A BR 0116672A BR 0116672 A BR0116672 A BR 0116672A
Authority
BR
Brazil
Prior art keywords
compound
pharmaceutically acceptable
acceptable salt
formula
preparing
Prior art date
Application number
BR0116672-7A
Other languages
Portuguese (pt)
Inventor
Vien Van Khau
Michael Edward Letourneau
Michael John Martinelli
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of BR0116672A publication Critical patent/BR0116672A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/06Antimigraine agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Abstract

"SAL FARMACEUTICAMENTE ACEITáVEL DE UM COMPOSTO, COMPOSTO, COMPOSIçãO FARMACêUTICA, USO DE UM SAL FARMACEUTICAMENTE ACEITáVEL, E, PROCESSO PARA PREPARAR UM COMPOSTO". A presente invenção proporciona novos sais farmaceuticamente aceitáveis de compostos de Fórmula (I) e de Fórmula (Ia), bem como métodos para usar os sais farmaceuticamente aceitáveis, e também proporciona processos para preparar compostos de Fórmula (I) e de Fórmula (Ia), ou seus sais farmaceuticamente aceitáveis. Os compostos de Fórmula (I) e de Fórmula (Ia) são úteis para o tratamento de distúrbios neurológicos, especialmente de enxaqueca."Pharmaceutically acceptable salt of a compound, compound, pharmaceutical composition, use of a pharmaceutically acceptable salt, and process for preparing a compound". The present invention provides novel pharmaceutically acceptable salts of compounds of Formula (I) and Formula (Ia), as well as methods for using pharmaceutically acceptable salts, and also provides processes for preparing compounds of Formula (I) and Formula (Ia). or pharmaceutically acceptable salts thereof. The compounds of Formula (I) and Formula (Ia) are useful for the treatment of neurological disorders, especially migraine.

BR0116672-7A 2001-01-05 2001-12-20 Pharmaceutically acceptable salt of a compound, compound, pharmaceutical composition, use of a pharmaceutically acceptable salt, and process for preparing a compound. BR0116672A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US26001401P 2001-01-05 2001-01-05
PCT/US2001/044715 WO2002053561A1 (en) 2001-01-05 2001-12-20 Excitatory amino acid receptor antagonists

Publications (1)

Publication Number Publication Date
BR0116672A true BR0116672A (en) 2003-09-23

Family

ID=22987455

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0116672-7A BR0116672A (en) 2001-01-05 2001-12-20 Pharmaceutically acceptable salt of a compound, compound, pharmaceutical composition, use of a pharmaceutically acceptable salt, and process for preparing a compound.

Country Status (23)

Country Link
EP (1) EP1351955A1 (en)
JP (1) JP2004520335A (en)
KR (1) KR20030066797A (en)
CN (1) CN1484642A (en)
AR (1) AR035679A1 (en)
BR (1) BR0116672A (en)
CA (1) CA2431545A1 (en)
CZ (1) CZ20031856A3 (en)
DZ (1) DZ3460A1 (en)
EA (1) EA200300770A1 (en)
EC (1) ECSP034682A (en)
HR (1) HRP20030544A2 (en)
HU (1) HUP0302528A2 (en)
IL (1) IL156138A0 (en)
MX (1) MXPA03005981A (en)
NO (1) NO20032973L (en)
NZ (1) NZ525821A (en)
PE (1) PE20020792A1 (en)
PL (1) PL361934A1 (en)
SK (1) SK8242003A3 (en)
TW (1) TW591023B (en)
WO (1) WO2002053561A1 (en)
ZA (1) ZA200304311B (en)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5284957A (en) * 1992-09-03 1994-02-08 Eli Lilly And Company Excitatory amino acid receptor antagonists
EP1053234A1 (en) * 1998-02-06 2000-11-22 Smithkline Beecham Plc Salts of paroxetine
GB9908175D0 (en) * 1999-04-09 1999-06-02 Lilly Co Eli Method of treating neurological disorders
TR200200066T2 (en) * 1999-07-06 2002-04-22 Eli Lilly And Company Selective iGluR5 receptor antagonists for the treatment of migraine

Also Published As

Publication number Publication date
JP2004520335A (en) 2004-07-08
IL156138A0 (en) 2003-12-23
KR20030066797A (en) 2003-08-09
TW591023B (en) 2004-06-11
CA2431545A1 (en) 2002-07-11
MXPA03005981A (en) 2003-09-10
EA200300770A1 (en) 2003-10-30
HRP20030544A2 (en) 2004-08-31
PE20020792A1 (en) 2002-09-06
DZ3460A1 (en) 2002-07-11
PL361934A1 (en) 2004-10-18
EP1351955A1 (en) 2003-10-15
SK8242003A3 (en) 2004-01-08
NO20032973D0 (en) 2003-06-27
NZ525821A (en) 2004-07-30
CN1484642A (en) 2004-03-24
CZ20031856A3 (en) 2003-09-17
ECSP034682A (en) 2003-08-29
NO20032973L (en) 2003-06-27
HUP0302528A2 (en) 2003-11-28
WO2002053561A1 (en) 2002-07-11
AR035679A1 (en) 2004-06-23
ZA200304311B (en) 2004-09-02

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 5A E 6A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 1964 DE 26/08/2008 E CONSIDERANDO A AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS.