BR0114942A - Reagente, e, conjunto para estimar o potencial hemostático de uma amostra de teste - Google Patents

Reagente, e, conjunto para estimar o potencial hemostático de uma amostra de teste

Info

Publication number
BR0114942A
BR0114942A BR0114942-3A BR0114942A BR0114942A BR 0114942 A BR0114942 A BR 0114942A BR 0114942 A BR0114942 A BR 0114942A BR 0114942 A BR0114942 A BR 0114942A
Authority
BR
Brazil
Prior art keywords
sample
dependent
patient
reagent
test sample
Prior art date
Application number
BR0114942-3A
Other languages
English (en)
Inventor
Liliana Tejidor
Trevor Baglin
Hema Doobay
Roger Luddington
Timothy J Fischer
Original Assignee
Bio M Rieux Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bio M Rieux Inc filed Critical Bio M Rieux Inc
Publication of BR0114942A publication Critical patent/BR0114942A/pt

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/86—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time or factors, or their receptors
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

"REAGENTE, E, CONJUNTO PARA ESTIMAR O POTENCIAL HEMOSTáTICO DE UMA AMOSTRA DE TESTE". Um reagente e conjunto são divulgados para determinar se um paciente é hipercoagulável, hipocoagulável ou normal. O teste envolve fornecer uma amostra de teste do paciente e iniciar a coagulação na amostra na presença de um ativador, que é adicionado à amostra em uma quantidade que resultará na fibrina dependente da tenase intrínseca. Depois a formação da polimerização da fibrina dependente da tenase intrinseca é monitorada durante um tempo de modo a derivar um perfil dependente do tempo, com os resultados do monitoramento da polimerização da fibrina determinando se o paciente é hipercoagulável, normal ou hipocoagulável. O ativador de coagulação é adicionado em uma quantidade que deflagra uma explosão de trombina que é dependente da fase de propagação e dos caminhos de amplificação. Deste modo, um único ensaio pode estimar o potencial hemostático de uma amostra.
BR0114942-3A 2000-10-27 2001-10-18 Reagente, e, conjunto para estimar o potencial hemostático de uma amostra de teste BR0114942A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/698,589 US6645768B1 (en) 2000-10-27 2000-10-27 Reagent and kit for determining global coagulability and hemostatic potential
PCT/US2001/032563 WO2002034109A2 (en) 2000-10-27 2001-10-18 A reagent and kit for determining global coagulability and hemostatic potential

Publications (1)

Publication Number Publication Date
BR0114942A true BR0114942A (pt) 2003-12-23

Family

ID=24805872

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0114942-3A BR0114942A (pt) 2000-10-27 2001-10-18 Reagente, e, conjunto para estimar o potencial hemostático de uma amostra de teste

Country Status (11)

Country Link
US (2) US6645768B1 (pt)
EP (1) EP1337858B1 (pt)
JP (1) JP4065195B2 (pt)
AT (1) ATE502303T1 (pt)
AU (2) AU2002215382B2 (pt)
BR (1) BR0114942A (pt)
CA (1) CA2427297A1 (pt)
DE (1) DE60144242D1 (pt)
ES (1) ES2363210T3 (pt)
MX (1) MXPA03003683A (pt)
WO (1) WO2002034109A2 (pt)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6743596B1 (en) * 2000-10-27 2004-06-01 Biomerieux, Inc. Method of determining global coagulability hemostatic potential
EP1546710A4 (en) 2002-09-10 2011-05-25 Placor Inc METHOD AND DEVICE FOR MONITORING THE THROMBOCYTE FUNCTION
WO2005017486A2 (en) * 2003-06-09 2005-02-24 Mann Kenneth G A global test of the hemostatic system
CA2566411A1 (en) * 2004-05-11 2005-11-24 Heptest Laboratories, Inc. Compositions, kit and one-step method for monitoring compounds having anti-factor xa and/or anti factor iia activities
EP1875232A2 (en) * 2005-04-25 2008-01-09 PlaCor, Inc. Methods and devices for monitoring platelet function
EP2380905A1 (en) * 2010-04-19 2011-10-26 Thrombotargets Europe, S.L. Phospholipid-enriched vesicles bearing tissue factor having haemostatic activities and uses thereof
US20140242707A1 (en) * 2011-07-21 2014-08-28 Philadelphia Health & Education Corporation D/B/A Drexel University College Of Medicine Compositions and Methods for Diagnosing Hypercoagulability and Hypocoagulability
US10188302B2 (en) * 2011-12-31 2019-01-29 The University Of Vermont And State Agriculture College Methods for dynamic visualization of clinical parameters over time
ES2959277T3 (es) * 2016-05-13 2024-02-22 Scripps Research Inst Composiciones y métodos para terapias antitrombóticas y hemostáticas
RU2660706C1 (ru) * 2017-09-26 2018-07-09 федеральное государственное бюджетное учреждение "Национальный медицинский исследовательский центр профилактической медицины" Министерства здравоохранения Российской Федерации (ФГБУ "НМИЦ ПМ" Минздрава России) Скрининг-тест определения контактного пути коагуляции (СТОКПК)
JP6952668B2 (ja) * 2018-09-28 2021-10-20 シスメックス株式会社 血液凝固分析方法、血液凝固分析装置、プログラム
EP3983810A1 (en) 2019-06-15 2022-04-20 Academisch Medisch Centrum Method for determining the risk of a thromboembolic event
JPWO2022145477A1 (pt) * 2020-12-28 2022-07-07

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4208479A (en) * 1977-07-14 1980-06-17 Syva Company Label modified immunoassays
NL8902406A (nl) 1989-09-27 1991-04-16 Hendrik Coenraad Hemker Prof D Werkwijze voor het bepalen van de endogene trombinepotentiaal van plasma, en bloed alsmede een bij deze werkwijze te gebruiken kit.
US5646046A (en) 1989-12-01 1997-07-08 Akzo Nobel N.V. Method and instrument for automatically performing analysis relating to thrombosis and hemostasis
JPH04228648A (ja) * 1990-12-27 1992-08-18 Bridgestone Corp エアバッグ
DE69224622T2 (de) 1991-10-04 1998-11-05 Dade Behring Inc Herstellung von prothrombinzeit-reagenzien aus rekombinantem menschlichem gewebefaktor und sythetischen phospholipiden
US5716795A (en) 1991-10-04 1998-02-10 Matschiner; John T. Thrombomodulin-based coagulometric assay of the protein C system
DE4133946A1 (de) 1991-10-14 1993-04-15 Behringwerke Ag Funktioneller test und reagenz zur bestimmung von fibrinogen
SE470274B (sv) 1991-11-13 1993-12-20 Bjoern Dahlbaeck Användning av en in vitro-metod för diagnos av blodkoagulationssjukdomar
JP3224607B2 (ja) 1992-09-11 2001-11-05 株式会社アズウェル 血液凝固第ｘｉｉｉ因子活性測定方法および該測定用試薬キット
US5472852A (en) 1993-09-15 1995-12-05 Oklahoma Medical Research Foundation Assay for detection of selective Protein C inhibition by patients
DE4427785A1 (de) 1994-08-08 1996-02-15 Behringwerke Ag Verfahren zum Nachweis von Störungen des Protein C/Protein S-Systems
ATE198772T1 (de) 1994-11-10 2001-02-15 Dade Behring Marburg Gmbh Verfahren zum spezifischen nachweis eines aktivierten gerinnungsfaktors v mit einer erhöhten stabilität gegenüber aktiviertem protein c
WO1998048283A1 (en) * 1997-04-23 1998-10-29 Instrumentation Laboratory S.P.A. Recombinant rabbit tissue factor based prothrombin time reagent
DE19749197A1 (de) * 1997-11-07 1999-05-12 Dade Behring Marburg Gmbh Verfahren zur Bestimmung des antikoagulatorischen Potentials einer Probe
US6245573B1 (en) * 1998-02-12 2001-06-12 University Of Medicine And Dentistry Of New Jersey Rapid assessment of the coagulant activity of blood
ATE274600T1 (de) * 1998-06-08 2004-09-15 Univ Vermont Verfahren zur bestimmung der blutgerinnung in plasma
US6627193B1 (en) * 1999-01-13 2003-09-30 University Of Georgia Research Foundation, Inc. Methods and compositions for control of blood coagulation

Also Published As

Publication number Publication date
AU1538202A (en) 2002-05-06
ATE502303T1 (de) 2011-04-15
EP1337858A4 (en) 2005-08-17
CA2427297A1 (en) 2002-05-02
AU2002215382B2 (en) 2005-11-24
WO2002034109A3 (en) 2002-08-15
DE60144242D1 (de) 2011-04-28
US6645768B1 (en) 2003-11-11
US20050191751A1 (en) 2005-09-01
EP1337858B1 (en) 2011-03-16
MXPA03003683A (es) 2003-08-07
WO2002034109A2 (en) 2002-05-02
JP4065195B2 (ja) 2008-03-19
ES2363210T3 (es) 2011-07-27
JP2004512511A (ja) 2004-04-22
EP1337858A2 (en) 2003-08-27

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 7A E 8A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 DA RPI 2021 DE 29/09/2009.