BR0111880A - produtos farmacêuticos agonistas de receptor de vitronectina para uso em terapia de combinação - Google Patents

produtos farmacêuticos agonistas de receptor de vitronectina para uso em terapia de combinação

Info

Publication number
BR0111880A
BR0111880A BRPI0111880-3A BR0111880A BR0111880A BR 0111880 A BR0111880 A BR 0111880A BR 0111880 A BR0111880 A BR 0111880A BR 0111880 A BR0111880 A BR 0111880A
Authority
BR
Brazil
Prior art keywords
pharmaceuticals
combination therapy
receptor agonist
vitronectin receptor
treatment
Prior art date
Application number
BRPI0111880-3A
Other languages
English (en)
Inventor
Thomas D Harris
John A Barrett
Alan P Carpenter Jr
Milind Rajopadhye
Original Assignee
Bristol Myers Squibb Pharma Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Pharma Co filed Critical Bristol Myers Squibb Pharma Co
Publication of BR0111880A publication Critical patent/BR0111880A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0038—Radiosensitizing, i.e. administration of pharmaceutical agents that enhance the effect of radiotherapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/0474—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
    • A61K51/0482—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group chelates from cyclic ligands, e.g. DOTA
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Optics & Photonics (AREA)
  • Cardiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Saccharide Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)

Abstract

"PRODUTOS FARMACêUTICOS AGONISTAS DE RECEPTOR DE VITRONECTINA PARA USO EM TERAPIA DE COMBINAçãO". A presente invenção descreve kits e composições inéditos que compreendem compostos da fórmula (I): úteis para o diagnóstico e o tratamento de câncer em terapia de combinação em um paciente. A presente invenção propõe compostos inéditos úteis para o tratamento de artrite reumatóide. Os produtos farmacêuticos são constituídos por uma porção direcionadora que se liga a um receptor que é regulado para cima durante angiogênese, um grupamento de ligação opcional e um radioisótopo efetivo do ponto de vista terapêutico ou uma porção passível de representação efetiva do ponto de vista diagnostico.
BRPI0111880-3A 2000-06-21 2001-06-21 produtos farmacêuticos agonistas de receptor de vitronectina para uso em terapia de combinação BR0111880A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US21321000P 2000-06-21 2000-06-21
PCT/US2001/019793 WO2001097848A2 (en) 2000-06-21 2001-06-21 Vitronectin receptor antagonist pharmaceuticals

Publications (1)

Publication Number Publication Date
BR0111880A true BR0111880A (pt) 2006-04-25

Family

ID=22794168

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0111880-3A BR0111880A (pt) 2000-06-21 2001-06-21 produtos farmacêuticos agonistas de receptor de vitronectina para uso em terapia de combinação

Country Status (12)

Country Link
EP (1) EP1307226B1 (pt)
JP (1) JP2004521066A (pt)
CN (1) CN1582166A (pt)
AT (1) ATE414541T1 (pt)
AU (2) AU7296501A (pt)
BR (1) BR0111880A (pt)
CA (1) CA2412854C (pt)
DE (1) DE60136632D1 (pt)
IL (1) IL152941A0 (pt)
MX (1) MXPA02012750A (pt)
NZ (1) NZ522925A (pt)
WO (1) WO2001097848A2 (pt)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6569402B1 (en) 1998-12-18 2003-05-27 Bristol-Myers Squibb Pharma Company Vitronectin receptor antagonist pharmaceuticals
WO2001085212A2 (en) 2000-05-08 2001-11-15 The University Of British Columbia Drug delivery systems for photodynamic therapy
WO2001097861A2 (en) * 2000-06-21 2001-12-27 Bristol-Myers Squibb Pharma Company Vitronectin receptor antagonist pharmaceuticals
CA2474386C (en) 2002-01-24 2011-07-05 Barnes-Jewish Hospital Integrin targeted imaging agents
EP1475105A1 (en) * 2003-05-09 2004-11-10 Schering AG Bone localising radiopharmaceutical and tubulin-interacting compound combinatorial radiotherapy
WO2004100996A1 (en) * 2003-05-12 2004-11-25 Bristol-Myers Squibb Pharma Company Vitronectin receptor antagonist compounds and their use in the preparation of radiopharmaceuticals
EP3101012A1 (en) 2015-06-04 2016-12-07 Bayer Pharma Aktiengesellschaft New gadolinium chelate compounds for use in magnetic resonance imaging
WO2018096082A1 (en) 2016-11-28 2018-05-31 Bayer Pharma Aktiengesellschaft High relaxivity gadolinium chelate compounds for use in magnetic resonance imaging
US11090395B2 (en) * 2018-09-14 2021-08-17 SeeCure Taiwan Co., Ltd. Composition for cross talk between estrogen receptors and cannabinoid receptors
CA3120665A1 (en) 2018-11-23 2020-05-28 Bayer Aktiengesellschaft Formulation of contrast media and process of preparation thereof

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6130231A (en) * 1996-11-27 2000-10-10 Dupont Pharmaceuticals Integrin receptor antagonists
US6120995A (en) * 1997-08-07 2000-09-19 Thomas Jefferson University Compositions that specifically bind to colorectal cancer cells and methods of using the same
US6093382A (en) * 1998-05-16 2000-07-25 Bracco Research Usa Inc. Metal complexes derivatized with folate for use in diagnostic and therapeutic applications
IL142958A0 (en) * 1998-12-18 2002-04-21 Du Pont Pharm Co Vitronectin receptor antagonist pharmaceuticals
CA2413957A1 (en) * 2000-06-21 2001-12-27 Bristol-Myers Squibb Pharma Company Vitronectin receptor antagonist pharmaceuticals for use in combination therapy
WO2001097861A2 (en) * 2000-06-21 2001-12-27 Bristol-Myers Squibb Pharma Company Vitronectin receptor antagonist pharmaceuticals
EP1311302A2 (en) * 2000-06-21 2003-05-21 Bristol-Myers Squibb Pharma Company Pharmaceuticals for the imaging of angiogenic disorders
CA2413538A1 (en) * 2000-07-06 2002-01-17 Bristol-Myers Squibb Pharma Company Stable radiopharmaceutical compositions and methods for preparation thereof

Also Published As

Publication number Publication date
CA2412854C (en) 2010-08-17
WO2001097848A3 (en) 2003-03-13
DE60136632D1 (de) 2009-01-02
IL152941A0 (en) 2003-06-24
MXPA02012750A (es) 2004-07-30
AU7296501A (en) 2002-01-02
AU2001272965C1 (en) 2006-06-29
AU2001272965B2 (en) 2005-11-17
EP1307226B1 (en) 2008-11-19
CN1582166A (zh) 2005-02-16
CA2412854A1 (en) 2001-12-27
WO2001097848A2 (en) 2001-12-27
EP1307226A2 (en) 2003-05-07
NZ522925A (en) 2006-08-31
ATE414541T1 (de) 2008-12-15
JP2004521066A (ja) 2004-07-15

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 9A E 10A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2144 DE 07/02/2012.