BR0111199A - Compostos heterocìclicos - Google Patents
Compostos heterocìclicosInfo
- Publication number
- BR0111199A BR0111199A BR0111199-0A BR0111199A BR0111199A BR 0111199 A BR0111199 A BR 0111199A BR 0111199 A BR0111199 A BR 0111199A BR 0111199 A BR0111199 A BR 0111199A
- Authority
- BR
- Brazil
- Prior art keywords
- lowering effect
- effect
- formula
- heterocyclic compounds
- blood
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4178—1,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
- A61K31/421—1,3-Oxazoles, e.g. pemoline, trimethadione
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
- A61K31/422—Oxazoles not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/426—1,3-Thiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D263/32—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D277/24—Radicals substituted by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Diabetes (AREA)
- General Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Child & Adolescent Psychology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Abstract
"COMPOSTOS HETEROCìCLICOS". A presente invenção apresenta um agente preventivo ou terapêutico para o hiperlipidemia, o qual compreende, como um ingrediente ativo, um composto heterocíclico da fórmula [1], ou um seu sal farmaceuticamente aceitável: em que: R^ 1^ é arila opcionalmente substituída ou um grupo heterocíclico aromático, Het é um grupo heterocíclico aromático divalente, D é alquileno, alquenileno, alquinileno, ou um outro ainda, e E é carbóxi, ou um outro ainda, e novos compostos entre os compostos heterocíclicos da fórmula [1] acima, que tem um efeito de redução de triglicerídeo no sangue, um efeito de redução de LDL-C, um efeito de redução de glicose no sangue, um efeito de redução de insulina no sangue, ou um efeito de aumento crescente de HDL-C ou um efeito de redução do índice aterogênico todos juntos, e desse modo é útil na prevenção ou no tratamento de hiperlipidemia, arteriosclerose, diabetes melito, hipertensão, obesidade, e similares.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2000156936 | 2000-05-26 | ||
PCT/JP2001/004400 WO2001090087A1 (fr) | 2000-05-26 | 2001-05-25 | Composes heterocycliques |
Publications (1)
Publication Number | Publication Date |
---|---|
BR0111199A true BR0111199A (pt) | 2003-04-01 |
Family
ID=18661643
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR0111199-0A BR0111199A (pt) | 2000-05-26 | 2001-05-25 | Compostos heterocìclicos |
Country Status (16)
Country | Link |
---|---|
US (4) | US7144906B2 (pt) |
EP (2) | EP1295875A4 (pt) |
JP (1) | JP3591514B2 (pt) |
KR (1) | KR100545507B1 (pt) |
CN (1) | CN1238347C (pt) |
AU (2) | AU2001258841B2 (pt) |
BR (1) | BR0111199A (pt) |
CA (1) | CA2410382A1 (pt) |
HU (1) | HUP0302397A3 (pt) |
IL (1) | IL152979A0 (pt) |
MX (1) | MXPA02011609A (pt) |
NO (1) | NO20025659L (pt) |
RU (1) | RU2259361C2 (pt) |
UA (1) | UA72625C2 (pt) |
WO (1) | WO2001090087A1 (pt) |
ZA (1) | ZA200209152B (pt) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2525302A1 (en) | 2003-05-12 | 2004-11-18 | David Bundle | Multivalent inhibitors of serum amyloid p component |
EP1479677A1 (en) * | 2003-05-19 | 2004-11-24 | Aventis Pharma Deutschland GmbH | New indole derivatives as factor xa inhibitors |
AU2004272428A1 (en) * | 2003-09-12 | 2005-03-24 | Nippon Shinyaku Co., Ltd. | Crystal of heterocyclic compound |
EP1709035A1 (en) * | 2004-01-09 | 2006-10-11 | Cadila Healthcare Ltd. | 1 , 3 - dioxane derivatives and analogues thereof useful in the treatment of i.a. obesity and diabetes |
JP2008510696A (ja) * | 2004-08-20 | 2008-04-10 | カディラ ヘルスケア リミティド | 新規抗糖尿病化合物 |
WO2006030892A1 (ja) * | 2004-09-17 | 2006-03-23 | Nippon Shinyaku Co., Ltd. | 複素環化合物の製造方法 |
WO2007096261A2 (en) * | 2006-02-21 | 2007-08-30 | F. Hoffmann-La Roche Ag | Process for the preparation of dioxane derivatives |
RU2444518C2 (ru) * | 2007-01-08 | 2012-03-10 | Сеул Нэшнл Юниверсити Индастри Фаундейшн | ПРОИЗВОДНОЕ ТИАЗОЛА КАК PPARδ ЛИГАНД И ФАРМАЦЕВТИЧЕСКИЙ, КОСМЕТИЧЕСКИЙ И ДИЕТИЧЕСКИЙ ПИЩЕВОЙ ПРОДУКТ, СОДЕРЖАЩИЙ ЕГО |
JP5357894B2 (ja) | 2008-12-01 | 2013-12-04 | 田辺三菱製薬株式会社 | チアゾール環を含むカルボン酸誘導体およびその医薬用途 |
PT2427415T (pt) * | 2009-05-08 | 2019-05-31 | Basf As | Ácidos gordos polinsaturados para o tratamento de doenças relacionadas com as áreas cardiovascular, metabólica e de doença inflamatória |
UA104489C2 (uk) * | 2009-10-01 | 2014-02-10 | Каділа Хелткере Лімітед | Сполуки для лікування дисліпідемії та споріднених хвороб |
LT3573611T (lt) * | 2017-01-24 | 2022-03-25 | Alphala Co., Ltd. | Amidų junginiai ir jų naudojimas |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1473212A (en) * | 1974-02-27 | 1977-05-11 | Wyeth John & Brother Ltd | Thiazolylmethyl acetic acid derivatives methods for their preparation and compositions containing them |
JPS60208971A (ja) * | 1984-03-30 | 1985-10-21 | Hisamitsu Pharmaceut Co Inc | 新規なオキサゾ−ル誘導体 |
ZW19786A1 (en) * | 1985-10-17 | 1988-05-18 | Hoffmann La Roche | Heterocyclic compounds |
FR2699172B1 (fr) | 1992-12-11 | 1995-01-20 | Adir | Nouveaux dérivés de 4-méthyl-1,3-oxazole, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent. |
US5614544A (en) * | 1993-09-14 | 1997-03-25 | Takeda Chemical Industries, Ltd. | Oxazolidinedione derivatives and their use |
WO1999031056A1 (fr) | 1997-12-12 | 1999-06-24 | Toyama Chemical Co., Ltd. | Derives d'ether alcoylique ou leurs sels, et antagonistes du calcium les contenant |
JP4345230B2 (ja) * | 1998-03-10 | 2009-10-14 | 小野薬品工業株式会社 | カルボン酸誘導体およびその誘導体を有効成分として含有する薬剤 |
US6664281B1 (en) * | 1998-08-27 | 2003-12-16 | Ono Pharmaceutical Co., Ltd. | Carboxylic acid derivatives and drugs containing the same as the active ingredient |
US6589969B1 (en) * | 1998-10-16 | 2003-07-08 | Ono Pharmaceutical Co., Ltd. | Carboxylic acid derivatives and drugs containing the same as the active ingredient |
GB0031109D0 (en) * | 2000-12-20 | 2001-01-31 | Glaxo Group Ltd | Chemical compounds |
GB0031107D0 (en) | 2000-12-20 | 2001-01-31 | Glaxo Group Ltd | Chemical compounds |
KR100654516B1 (ko) * | 2001-05-15 | 2006-12-05 | 에프. 호프만-라 로슈 아게 | 당뇨병 치료에서 ppar-알파 및 -감마 활성제로서사용하기 위한 카복실산 치환된 옥사졸 유도체 |
JP4436129B2 (ja) * | 2001-08-31 | 2010-03-24 | サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング | ジアリールシクロアルキル誘導体、その製造法及びppar−活性剤としてのその使用 |
US6716842B2 (en) * | 2002-04-05 | 2004-04-06 | Warner-Lambert Company, Llc | Antidiabetic agents |
-
2001
- 2001-05-25 UA UA2002129620A patent/UA72625C2/uk unknown
- 2001-05-25 AU AU2001258841A patent/AU2001258841B2/en not_active Ceased
- 2001-05-25 RU RU2002135079/04A patent/RU2259361C2/ru not_active IP Right Cessation
- 2001-05-25 EP EP01932267A patent/EP1295875A4/en not_active Withdrawn
- 2001-05-25 CA CA002410382A patent/CA2410382A1/en not_active Abandoned
- 2001-05-25 JP JP2001586275A patent/JP3591514B2/ja not_active Expired - Fee Related
- 2001-05-25 US US10/276,670 patent/US7144906B2/en not_active Expired - Fee Related
- 2001-05-25 HU HU0302397A patent/HUP0302397A3/hu unknown
- 2001-05-25 KR KR1020027016023A patent/KR100545507B1/ko not_active IP Right Cessation
- 2001-05-25 BR BR0111199-0A patent/BR0111199A/pt not_active IP Right Cessation
- 2001-05-25 CN CNB018101402A patent/CN1238347C/zh not_active Expired - Fee Related
- 2001-05-25 EP EP05018610A patent/EP1634876A3/en not_active Withdrawn
- 2001-05-25 WO PCT/JP2001/004400 patent/WO2001090087A1/ja not_active Application Discontinuation
- 2001-05-25 AU AU5884101A patent/AU5884101A/xx active Pending
- 2001-05-25 MX MXPA02011609A patent/MXPA02011609A/es not_active Application Discontinuation
- 2001-05-25 IL IL15297901A patent/IL152979A0/xx unknown
-
2002
- 2002-11-11 ZA ZA200209152A patent/ZA200209152B/en unknown
- 2002-11-25 NO NO20025659A patent/NO20025659L/no not_active Application Discontinuation
-
2004
- 2004-02-17 US US10/781,475 patent/US6998412B2/en not_active Expired - Fee Related
- 2004-02-17 US US10/781,293 patent/US7030143B2/en not_active Expired - Fee Related
- 2004-02-17 US US10/781,433 patent/US7022723B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
US7144906B2 (en) | 2006-12-05 |
KR100545507B1 (ko) | 2006-01-24 |
UA72625C2 (uk) | 2005-03-15 |
EP1634876A2 (en) | 2006-03-15 |
NO20025659D0 (no) | 2002-11-25 |
IL152979A0 (en) | 2003-06-24 |
US20050009785A1 (en) | 2005-01-13 |
ZA200209152B (en) | 2004-02-11 |
CA2410382A1 (en) | 2002-11-25 |
KR20030019399A (ko) | 2003-03-06 |
HUP0302397A2 (hu) | 2003-11-28 |
EP1295875A1 (en) | 2003-03-26 |
AU2001258841B2 (en) | 2005-06-23 |
CN1238347C (zh) | 2006-01-25 |
CN1430612A (zh) | 2003-07-16 |
HUP0302397A3 (en) | 2007-02-28 |
RU2259361C2 (ru) | 2005-08-27 |
NO20025659L (no) | 2002-11-25 |
WO2001090087A1 (fr) | 2001-11-29 |
US7022723B2 (en) | 2006-04-04 |
MXPA02011609A (es) | 2003-03-27 |
US7030143B2 (en) | 2006-04-18 |
EP1634876A3 (en) | 2007-03-14 |
AU5884101A (en) | 2001-12-03 |
US20040162325A1 (en) | 2004-08-19 |
US20050009892A1 (en) | 2005-01-13 |
JP3591514B2 (ja) | 2004-11-24 |
EP1295875A4 (en) | 2004-05-06 |
US6998412B2 (en) | 2006-02-14 |
US20030166697A1 (en) | 2003-09-04 |
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