BR0108433A - flavoring systems for pharmaceutical compositions and methods for making such compositions - Google Patents

flavoring systems for pharmaceutical compositions and methods for making such compositions

Info

Publication number
BR0108433A
BR0108433A BRPI0108433-0A BR0108433A BR0108433A BR 0108433 A BR0108433 A BR 0108433A BR 0108433 A BR0108433 A BR 0108433A BR 0108433 A BR0108433 A BR 0108433A
Authority
BR
Brazil
Prior art keywords
flavoring
pharmaceutical compositions
mixtures
making
compositions
Prior art date
Application number
BRPI0108433-0A
Other languages
Portuguese (pt)
Inventor
Laman Alani
Donald P Gauwitz
Dilip Kaul
John M Lipari
Soumojeet Ghosh
Kennan C Marsh
Richard H Whelan
Vanik D Petrossian
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Lab filed Critical Abbott Lab
Publication of BR0108433A publication Critical patent/BR0108433A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/426—1,3-Thiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/513—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Virology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Fats And Perfumes (AREA)

Abstract

"SISTEMAS FLAVORIZANTES PARA COMPOSIçõES FARMACêUTICAS E MéTODOS PARA FAZER TAIS COMPOSIçõES". A presente invenção se refere a um sistema flavorizante para uma composição farmacêutica líquida e a composições farmacêuticas contendo tais sistemas flavorizantes. os sistemas flavorizantes da invenção incluem pelo menos um agente adoçante, pelo menos dois ingredientes com sabor, e pelo menos um modificador de sabor selecionado do grupo consistindo em ácido cítrico, citrato de sódio, cloreto de sódio, e misturas dos mesmos. Pelo menos dois dos ingredientes com sabor são selecionados do grupo consistindo em um ingrediente com sabor de baunilha, um ingrediente com sabor de hortelã-pimenta, um ingrediente com sabor de mentol, um ingrediente com sabor de algodão doce, e misturas dos mesmos. O um ou mais agentes adoçantes compreendem glicerina, glicirrizinato de monoamónio, sacarina sódica, acesulfamo de potássio, xarope de milho com alto teor de frutose, e/ou misturas dos mesmos. As composições farmacêuticas da invenção incluem um sistema flavorizante da invenção, um sistema solvente e pelo menos um agente farmaceuticamente ativo, tais como lopinavir ou derivados do mesmo, ritonavir ou derivados do mesmo, ou misturas dos mesmos. Os métodos para fazer tais composições farmacêuticas líquidas são também descritos."FAVORING SYSTEMS FOR PHARMACEUTICAL COMPOSITIONS AND METHODS FOR MAKING SUCH COMPOSITIONS". The present invention relates to a flavoring system for a liquid pharmaceutical composition and pharmaceutical compositions containing such flavoring systems. The flavoring systems of the invention include at least one sweetening agent, at least two flavoring ingredients, and at least one flavor modifier selected from the group consisting of citric acid, sodium citrate, sodium chloride, and mixtures thereof. At least two of the flavored ingredients are selected from the group consisting of a vanilla flavored ingredient, a peppermint flavored ingredient, a menthol flavored ingredient, a cotton candy flavored ingredient, and mixtures thereof. The one or more sweetening agents comprise glycerine, monoammonium glycyrrizinate, sodium saccharin, potassium acesulfam, high fructose corn syrup, and / or mixtures thereof. Pharmaceutical compositions of the invention include a flavoring system of the invention, a solvent system and at least one pharmaceutically active agent such as lopinavir or derivatives thereof, ritonavir or derivatives thereof, or mixtures thereof. Methods for making such liquid pharmaceutical compositions are also described.

BRPI0108433-0A 2000-09-05 2001-09-04 flavoring systems for pharmaceutical compositions and methods for making such compositions BR0108433A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US65519200A 2000-09-05 2000-09-05
PCT/US2001/027415 WO2002020057A2 (en) 2000-09-05 2001-09-04 Flavoring systems for pharmaceutical compositions and methods of making such compositions

Publications (1)

Publication Number Publication Date
BR0108433A true BR0108433A (en) 2006-06-06

Family

ID=24627898

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0108433-0A BR0108433A (en) 2000-09-05 2001-09-04 flavoring systems for pharmaceutical compositions and methods for making such compositions

Country Status (10)

Country Link
EP (1) EP1315487A2 (en)
JP (1) JP2004522698A (en)
AR (1) AR030715A1 (en)
AU (1) AU2001288695A1 (en)
BR (1) BR0108433A (en)
CA (1) CA2417258A1 (en)
MX (1) MXPA03001952A (en)
PE (1) PE20020373A1 (en)
UY (1) UY26925A1 (en)
WO (1) WO2002020057A2 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE329579T1 (en) 1999-11-12 2006-07-15 Abbott Lab SOLID DISPERSION WITH RITONAVIR, FENOFIBRATE OR GRISEOFULVIN
AU2003295589A1 (en) * 2002-11-22 2004-06-18 Noville, Inc. Oral compositions which mask the salty taste of salts
US8025899B2 (en) 2003-08-28 2011-09-27 Abbott Laboratories Solid pharmaceutical dosage form
GB2423711B (en) * 2005-10-24 2007-02-14 Fortune Apex Dev Ltd Method for preparing a pharmaceutical composition with enhanced mucoadhesion
JPWO2013129436A1 (en) * 2012-02-29 2015-07-30 武田薬品工業株式会社 Oral
US8771651B2 (en) * 2012-09-10 2014-07-08 Johnson & Johnson Consumer Companies, Inc. Mouth rinses and tooth sensitivity treatment compositions

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL111991A (en) * 1994-01-28 2000-07-26 Abbott Lab Liquid pharmaceutical composition of HIV protease inhibitors in organic solvent
AU3146997A (en) * 1996-06-03 1998-01-05 Merck & Co., Inc. Pediatric formulation for hiv protease inhibitors

Also Published As

Publication number Publication date
JP2004522698A (en) 2004-07-29
UY26925A1 (en) 2002-04-26
AR030715A1 (en) 2003-09-03
AU2001288695A1 (en) 2002-03-22
EP1315487A2 (en) 2003-06-04
MXPA03001952A (en) 2003-09-10
WO2002020057A2 (en) 2002-03-14
PE20020373A1 (en) 2002-05-13
CA2417258A1 (en) 2002-03-14
WO2002020057A3 (en) 2002-05-10

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Legal Events

Date Code Title Description
B08F Application fees: dismissal - article 86 of industrial property law

Free format text: REFERENTE A 5A, 6A E 7A ANUIDADES.

B08K Lapse as no evidence of payment of the annual fee has been furnished to inpi (acc. art. 87)

Free format text: REFERENTE AO DESPACHO PUBLICADO NA RPI 1963 DE 19.08.2008.