AR030715A1 - FLAVORING SYSTEMS FOR PHARMACEUTICAL COMPOSITIONS AND METHODS TO MAKE SUCH COMPOSITIONS - Google Patents

FLAVORING SYSTEMS FOR PHARMACEUTICAL COMPOSITIONS AND METHODS TO MAKE SUCH COMPOSITIONS

Info

Publication number
AR030715A1
AR030715A1 ARP010104207A ARP010104207A AR030715A1 AR 030715 A1 AR030715 A1 AR 030715A1 AR P010104207 A ARP010104207 A AR P010104207A AR P010104207 A ARP010104207 A AR P010104207A AR 030715 A1 AR030715 A1 AR 030715A1
Authority
AR
Argentina
Prior art keywords
flavored
mixtures
pharmaceutical compositions
flavoring
flavoring systems
Prior art date
Application number
ARP010104207A
Other languages
Spanish (es)
Inventor
Laman Alani
Donald Gauwitz
Dilip Kaul
John Lipari
Keenan Marsh
Richard Whelan
Vanik Petrossian
Soumojeet Ghosh
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Lab filed Critical Abbott Lab
Publication of AR030715A1 publication Critical patent/AR030715A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/426—1,3-Thiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/513—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Virology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Fats And Perfumes (AREA)

Abstract

Sistemas saborizantes para una composicion farmacéutica líquida y composiciones farmacéuticas que contienen dichos sistemas saborizantes. Los sistemas saborizantes de la invencion incluyen por lo menos un agente edulcorante, por lo menos dos ingredientes con sabor, y por lo menos un modificador del sabor que se selecciona entre el grupo que consiste en ácido cítrico, citrato de sodio, cloruro de sodio y mezclas de los mismos. Por lo menos dos de los ingredientes saborizados se seleccionan entre el grupo que consiste en un ingrediente con sabor a vainilla, un ingrediente con sabor a menta, un ingrediente con sabor a mentol, un ingrediente con sabor a algodon de azucar, y mezclas de los mismos. El (los) agente(s) edulcorante(s) comprende(n) glicerina, glicirricinato de monoamonio, sacarina sodica, acesulfame potásico, jarabe de maíz de alta fructosa, y/o mezclas de los mismos. Las composiciones farmacéuticas de la invencion incluyen un sistema saborizante de la invencion, un sistema solvente, y por lo menos un agente farmacéuticamente activo, como por ejemplo lopinavir o derivados del mismo, ritonavir o derivados del mismo, o mezclas de los mismos. También se describen métodos para hacer dichas composiciones farmacéuticas líquidas.Flavoring systems for a liquid pharmaceutical composition and pharmaceutical compositions containing said flavoring systems. The flavoring systems of the invention include at least one sweetening agent, at least two flavored ingredients, and at least one flavor modifier that is selected from the group consisting of citric acid, sodium citrate, sodium chloride and mixtures thereof. At least two of the flavored ingredients are selected from the group consisting of a vanilla-flavored ingredient, a mint-flavored ingredient, a menthol-flavored ingredient, a sugar-flavored cotton-flavored ingredient, and mixtures of same. The sweetening agent (s) comprises glycerin, monoammonium glycyrrhizinate, sodium saccharin, potassium acesulfame, high fructose corn syrup, and / or mixtures thereof. The pharmaceutical compositions of the invention include a flavoring system of the invention, a solvent system, and at least one pharmaceutically active agent, such as lopinavir or derivatives thereof, ritonavir or derivatives thereof, or mixtures thereof. Methods for making such liquid pharmaceutical compositions are also described.

ARP010104207A 2000-09-05 2001-09-04 FLAVORING SYSTEMS FOR PHARMACEUTICAL COMPOSITIONS AND METHODS TO MAKE SUCH COMPOSITIONS AR030715A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US65519200A 2000-09-05 2000-09-05

Publications (1)

Publication Number Publication Date
AR030715A1 true AR030715A1 (en) 2003-09-03

Family

ID=24627898

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP010104207A AR030715A1 (en) 2000-09-05 2001-09-04 FLAVORING SYSTEMS FOR PHARMACEUTICAL COMPOSITIONS AND METHODS TO MAKE SUCH COMPOSITIONS

Country Status (10)

Country Link
EP (1) EP1315487A2 (en)
JP (1) JP2004522698A (en)
AR (1) AR030715A1 (en)
AU (1) AU2001288695A1 (en)
BR (1) BR0108433A (en)
CA (1) CA2417258A1 (en)
MX (1) MXPA03001952A (en)
PE (1) PE20020373A1 (en)
UY (1) UY26925A1 (en)
WO (1) WO2002020057A2 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1175205B1 (en) 1999-11-12 2006-06-14 Abbott Laboratories Solid dispersion comprising ritonavir, fenofibrate or griseofulvin
BR0316318A (en) * 2002-11-22 2005-09-27 Firmenich & Cie Oral composition, and, method of masking the salty taste of a salt in an oral composition
US8025899B2 (en) 2003-08-28 2011-09-27 Abbott Laboratories Solid pharmaceutical dosage form
GB2423711B (en) * 2005-10-24 2007-02-14 Fortune Apex Dev Ltd Method for preparing a pharmaceutical composition with enhanced mucoadhesion
JPWO2013129436A1 (en) * 2012-02-29 2015-07-30 武田薬品工業株式会社 Oral
US8771651B2 (en) * 2012-09-10 2014-07-08 Johnson & Johnson Consumer Companies, Inc. Mouth rinses and tooth sensitivity treatment compositions

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL111991A (en) * 1994-01-28 2000-07-26 Abbott Lab Liquid pharmaceutical composition of HIV protease inhibitors in organic solvent
WO1997046222A1 (en) * 1996-06-03 1997-12-11 Merck & Co., Inc. Pediatric formulation for hiv protease inhibitors

Also Published As

Publication number Publication date
UY26925A1 (en) 2002-04-26
WO2002020057A2 (en) 2002-03-14
BR0108433A (en) 2006-06-06
MXPA03001952A (en) 2003-09-10
EP1315487A2 (en) 2003-06-04
CA2417258A1 (en) 2002-03-14
PE20020373A1 (en) 2002-05-13
AU2001288695A1 (en) 2002-03-22
WO2002020057A3 (en) 2002-05-10
JP2004522698A (en) 2004-07-29

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