BR0015039A - Método para administrar um inibidor fosfodiesterase 4 - Google Patents
Método para administrar um inibidor fosfodiesterase 4Info
- Publication number
- BR0015039A BR0015039A BR0015039-8A BR0015039A BR0015039A BR 0015039 A BR0015039 A BR 0015039A BR 0015039 A BR0015039 A BR 0015039A BR 0015039 A BR0015039 A BR 0015039A
- Authority
- BR
- Brazil
- Prior art keywords
- inhibitor
- phosphodiesterase
- administering
- rate
- administered
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2009—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/74—Synthetic polymeric materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Inorganic Chemistry (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
Abstract
"MéTODO PARA ADMINISTRAR UM INIBIDOR FOSFODIESTERASE 4". Essa invenção se refere a um método de tratamento pra o aumento de dose de um inibidor PDE4 que pode ser administrado de uma vez e ser bem tolerado pelo paciente mediante a redução da taxa de absorção ou da taxa de elevação da concentração plasmática do inibidor.
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US16247799P | 1999-10-29 | 1999-10-29 | |
US16264199P | 1999-11-01 | 1999-11-01 | |
US17981700P | 2000-02-02 | 2000-02-02 | |
PCT/US2000/029453 WO2001032165A1 (en) | 1999-10-29 | 2000-10-26 | Method for administering a phosphodiesterase 4 inhibitor |
Publications (1)
Publication Number | Publication Date |
---|---|
BR0015039A true BR0015039A (pt) | 2002-06-25 |
Family
ID=27388757
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR0015039-8A BR0015039A (pt) | 1999-10-29 | 2000-10-26 | Método para administrar um inibidor fosfodiesterase 4 |
Country Status (29)
Country | Link |
---|---|
US (1) | US20030212112A1 (pt) |
EP (1) | EP1225884A4 (pt) |
JP (1) | JP2003513038A (pt) |
KR (1) | KR20020050249A (pt) |
CN (1) | CN1387433A (pt) |
AP (1) | AP2002002446A0 (pt) |
AR (1) | AR026254A1 (pt) |
AU (1) | AU772909B2 (pt) |
BG (1) | BG106623A (pt) |
BR (1) | BR0015039A (pt) |
CA (1) | CA2389293A1 (pt) |
CO (1) | CO5271676A1 (pt) |
CZ (1) | CZ20021443A3 (pt) |
DZ (1) | DZ3249A1 (pt) |
EA (1) | EA200200502A1 (pt) |
HK (1) | HK1049105A1 (pt) |
HU (1) | HUP0203682A3 (pt) |
IL (1) | IL148813A0 (pt) |
MA (1) | MA25562A1 (pt) |
MX (1) | MXPA02004220A (pt) |
NO (1) | NO20021937L (pt) |
NZ (1) | NZ518002A (pt) |
OA (1) | OA12078A (pt) |
PE (1) | PE20011004A1 (pt) |
PL (1) | PL355262A1 (pt) |
SK (1) | SK7292002A3 (pt) |
TR (1) | TR200201150T2 (pt) |
UY (1) | UY26422A1 (pt) |
WO (1) | WO2001032165A1 (pt) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AR029984A1 (es) * | 2000-07-27 | 2003-07-23 | Smithkline Beecham Corp | Metodo para reducir las exacerbaciones asociadas copd ambito |
MY140561A (en) | 2002-02-20 | 2009-12-31 | Nycomed Gmbh | Dosage form containing pde 4 inhibitor as active ingredient |
DE10207160A1 (de) * | 2002-02-20 | 2003-12-18 | Altana Pharma Ag | Darreichungsform enthaltend PDE 4-Hemmer als Wirkstoff |
MXPA04011612A (es) * | 2002-05-28 | 2005-03-07 | Altana Pharma Ag | Uso oftalmologico de roflumilasto para el tratamiento de enfermedades del ojo. |
US6822114B1 (en) | 2002-10-08 | 2004-11-23 | Albemarle Corporation | Process for production of fluoroalkoxy-substituted benzamides and their intermediates |
BRPI0406427B8 (pt) | 2003-03-10 | 2021-05-25 | Astrazeneca Ab | processo para a preparação de roflumilast |
WO2004096274A1 (ja) * | 2003-03-31 | 2004-11-11 | Kyowa Hakko Kogyo Co., Ltd. | 気道内投与剤 |
US20050026883A1 (en) * | 2003-07-31 | 2005-02-03 | Robinson Cynthia B. | Combination of dehydroepiandrosterone or dehydroepiandrosterone-sulfate with a PDE-4 inhibitor for treatment of asthma or chronic obstructive pulmonary disease |
DK1861074T3 (da) | 2005-03-16 | 2013-07-29 | Takeda Gmbh | Smagsmaskeret doseringsform indeholdende roflumilast |
EP2506711B1 (en) * | 2009-12-03 | 2019-04-03 | OPKO Health, Inc. | Hypersulfated disaccharide formulations |
PE20142318A1 (es) * | 2011-12-27 | 2015-01-16 | Celgene Corp | Formulaciones de (+)-2-[1-(3-etoxi-4-metoxi-fenil)-2-metansulfonil-etil]-4-acetilaminoisoindolin-1,3-diona |
CN103536582A (zh) * | 2013-10-12 | 2014-01-29 | 云南龙海天然植物药业有限公司 | 罗氟司特干粉吸入剂 |
WO2019147824A1 (en) | 2018-01-26 | 2019-08-01 | Progenity, Inc. | Treatment of a disease of the gastrointestinal tract with a pde4 inhibitor |
EP3883635A1 (en) | 2018-11-19 | 2021-09-29 | Progenity, Inc. | Methods and devices for treating a disease with biotherapeutics |
US11707610B2 (en) | 2019-12-13 | 2023-07-25 | Biora Therapeutics, Inc. | Ingestible device for delivery of therapeutic agent to the gastrointestinal tract |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4684516A (en) * | 1983-08-01 | 1987-08-04 | Alra Laboratories, Inc. | Sustained release tablets and method of making same |
MY121142A (en) * | 1999-02-23 | 2005-12-30 | Smithkline Beecham Corp | Controlled release formulation for treating copd |
AR035987A1 (es) * | 1999-03-01 | 2004-08-04 | Smithkline Beecham Corp | Uso de un compuesto inhibidor de la pde 4 para la manufactura de un medicamento y el medicamento para tratar asma inducida por ejercicio |
-
2000
- 2000-10-26 HU HU0203682A patent/HUP0203682A3/hu unknown
- 2000-10-26 IL IL14881300A patent/IL148813A0/xx unknown
- 2000-10-26 AU AU13445/01A patent/AU772909B2/en not_active Ceased
- 2000-10-26 CO CO00081570A patent/CO5271676A1/es not_active Application Discontinuation
- 2000-10-26 AR ARP000105644A patent/AR026254A1/es not_active Application Discontinuation
- 2000-10-26 NZ NZ518002A patent/NZ518002A/en unknown
- 2000-10-26 EP EP00975385A patent/EP1225884A4/en not_active Withdrawn
- 2000-10-26 JP JP2001534370A patent/JP2003513038A/ja not_active Withdrawn
- 2000-10-26 TR TR2002/01150T patent/TR200201150T2/xx unknown
- 2000-10-26 WO PCT/US2000/029453 patent/WO2001032165A1/en not_active Application Discontinuation
- 2000-10-26 MX MXPA02004220A patent/MXPA02004220A/es unknown
- 2000-10-26 BR BR0015039-8A patent/BR0015039A/pt not_active IP Right Cessation
- 2000-10-26 CA CA002389293A patent/CA2389293A1/en not_active Abandoned
- 2000-10-26 SK SK729-2002A patent/SK7292002A3/sk unknown
- 2000-10-26 AP APAP/P/2002/002446A patent/AP2002002446A0/en unknown
- 2000-10-26 OA OA1200200126A patent/OA12078A/en unknown
- 2000-10-26 PL PL00355262A patent/PL355262A1/xx unknown
- 2000-10-26 DZ DZ003249A patent/DZ3249A1/fr active
- 2000-10-26 CZ CZ20021443A patent/CZ20021443A3/cs unknown
- 2000-10-26 CN CN00815150A patent/CN1387433A/zh active Pending
- 2000-10-26 KR KR1020027005448A patent/KR20020050249A/ko not_active Application Discontinuation
- 2000-10-26 EA EA200200502A patent/EA200200502A1/ru unknown
- 2000-10-27 PE PE2000001157A patent/PE20011004A1/es not_active Application Discontinuation
- 2000-10-30 UY UY26422A patent/UY26422A1/es not_active Application Discontinuation
-
2002
- 2002-04-17 BG BG106623A patent/BG106623A/bg unknown
- 2002-04-24 NO NO20021937A patent/NO20021937L/no not_active Application Discontinuation
- 2002-04-26 MA MA26618A patent/MA25562A1/fr unknown
- 2002-12-19 HK HK02109231.8A patent/HK1049105A1/zh unknown
-
2003
- 2003-05-02 US US10/429,666 patent/US20030212112A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
EP1225884A4 (en) | 2005-06-15 |
AU1344501A (en) | 2001-05-14 |
SK7292002A3 (en) | 2002-12-03 |
AP2002002446A0 (en) | 2002-03-31 |
CA2389293A1 (en) | 2001-05-10 |
EA200200502A1 (ru) | 2002-10-31 |
AR026254A1 (es) | 2003-02-05 |
NZ518002A (en) | 2004-01-30 |
WO2001032165A1 (en) | 2001-05-10 |
DZ3249A1 (fr) | 2001-05-10 |
MA25562A1 (fr) | 2002-10-01 |
CZ20021443A3 (cs) | 2003-01-15 |
PE20011004A1 (es) | 2001-09-28 |
EP1225884A1 (en) | 2002-07-31 |
NO20021937D0 (no) | 2002-04-24 |
NO20021937L (no) | 2002-05-30 |
MXPA02004220A (es) | 2002-10-17 |
OA12078A (en) | 2003-05-28 |
PL355262A1 (en) | 2004-04-05 |
HK1049105A1 (zh) | 2003-05-02 |
CN1387433A (zh) | 2002-12-25 |
CO5271676A1 (es) | 2003-04-30 |
HUP0203682A3 (en) | 2003-10-28 |
AU772909B2 (en) | 2004-05-13 |
HUP0203682A2 (hu) | 2003-04-28 |
KR20020050249A (ko) | 2002-06-26 |
TR200201150T2 (tr) | 2002-09-23 |
IL148813A0 (en) | 2002-09-12 |
JP2003513038A (ja) | 2003-04-08 |
BG106623A (bg) | 2003-02-28 |
UY26422A1 (es) | 2001-07-31 |
US20030212112A1 (en) | 2003-11-13 |
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Legal Events
Date | Code | Title | Description |
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B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 8A ANUIDADE. |
|
B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 DA RPI 2008 DE 30/06/2009. |