BR0014573A - Fragmento de ácido nucléico isolado, polipeptìdeo, gene quimérico, célula hospedeira, célula hospedeira transformada, método de alteração do nìvel de expressão de uma proteìna cis- preniltransferase vegetal em células hospedeiras, método de obtenção de um fragmento de ácido nucléico e produto - Google Patents

Fragmento de ácido nucléico isolado, polipeptìdeo, gene quimérico, célula hospedeira, célula hospedeira transformada, método de alteração do nìvel de expressão de uma proteìna cis- preniltransferase vegetal em células hospedeiras, método de obtenção de um fragmento de ácido nucléico e produto

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Publication number
BR0014573A
BR0014573A BR0014573-4A BR0014573A BR0014573A BR 0014573 A BR0014573 A BR 0014573A BR 0014573 A BR0014573 A BR 0014573A BR 0014573 A BR0014573 A BR 0014573A
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BR
Brazil
Prior art keywords
host cell
nucleic acid
acid fragment
altering
polypeptide
Prior art date
Application number
BR0014573-4A
Other languages
English (en)
Inventor
Chris Coldren
Dennis Flint
David L Hallahan
Hong Wang
Original Assignee
Du Pont
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Du Pont filed Critical Du Pont
Publication of BR0014573A publication Critical patent/BR0014573A/pt

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52Genes encoding for enzymes or proenzymes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/1085Transferases (2.) transferring alkyl or aryl groups other than methyl groups (2.5)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8243Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8261Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
    • C12N15/8271Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance
    • C12N15/8279Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance

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  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Nutrition Science (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)

Abstract

"FRAGMENTO DE áCIDO NUCLéICO ISOLADO, POLIPEPTìDEO, GENE QUIMéRICO, CéLULA HOSPEDEIRA, CéLULA HOSPEDEIRA TRANSFORMADA, MéTODO DE ALTERAçãO DO NìVEL DE EXPRESSãO DE UMA PROTEìNA CIS-PRENILTRANSFERASE VEGETAL EM CéLULAS HOSPEDEIRAS, MéTODO DE OBTENçãO DE UM FRAGMENTO DE áCIDO NUCLéICO E PRODUTO". A presente invenção refere-se a fragmentos de ácidos nucléicos codificadores de proteínas vegetais que são homólogas as cispreniltransferases UPP sintase da bactéria Micrococcus luteus ou Dedol-PP sintase da levedura Saccharomyces cerevisiae. Mais especificamente, a presente invenção refere-se a homólogos de cis-preniltransferase de trigo, uva, soja, arroz, margarida africana, látex de seringueira e calêndula.
BR0014573-4A 1999-09-21 2000-09-21 Fragmento de ácido nucléico isolado, polipeptìdeo, gene quimérico, célula hospedeira, célula hospedeira transformada, método de alteração do nìvel de expressão de uma proteìna cis- preniltransferase vegetal em células hospedeiras, método de obtenção de um fragmento de ácido nucléico e produto BR0014573A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US15504699P 1999-09-21 1999-09-21
PCT/US2000/025856 WO2001021650A2 (en) 1999-09-21 2000-09-21 Cis-prenyltransferases from plants

Publications (1)

Publication Number Publication Date
BR0014573A true BR0014573A (pt) 2002-06-18

Family

ID=22553920

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0014573-4A BR0014573A (pt) 1999-09-21 2000-09-21 Fragmento de ácido nucléico isolado, polipeptìdeo, gene quimérico, célula hospedeira, célula hospedeira transformada, método de alteração do nìvel de expressão de uma proteìna cis- preniltransferase vegetal em células hospedeiras, método de obtenção de um fragmento de ácido nucléico e produto

Country Status (7)

Country Link
US (3) US6645747B1 (pt)
EP (1) EP1214338A2 (pt)
KR (1) KR20020040810A (pt)
AU (1) AU7598200A (pt)
BR (1) BR0014573A (pt)
CA (1) CA2381020A1 (pt)
WO (1) WO2001021650A2 (pt)

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BR0010616A (pt) 1999-04-15 2002-05-07 Calgene Llc Sequências de ácido nucléico a proteìnas envolvidas em sìntese de isoprenóide
US6872815B1 (en) 2000-10-14 2005-03-29 Calgene Llc Nucleic acid sequences to proteins involved in tocopherol synthesis
WO2002012478A2 (en) 2000-08-07 2002-02-14 Monsanto Technology, Llc Methyl-d-erythritol phosphate pathway genes
US7161061B2 (en) 2001-05-09 2007-01-09 Monsanto Technology Llc Metabolite transporters
JP2004533244A (ja) 2001-05-09 2004-11-04 モンサント テクノロジー リミテッド ライアビリティー カンパニー TyrA遺伝子及びその使用法
US7244877B2 (en) 2001-08-17 2007-07-17 Monsanto Technology Llc Methyltransferase from cotton and uses thereof
CN100400661C (zh) 2001-10-25 2008-07-09 孟山都技术有限公司 芳族甲基转移酶及其应用
WO2003038724A2 (en) * 2001-11-01 2003-05-08 The University Of British Columbia Methods and apparatus for protein sequence analysis
CA2478957C (en) 2002-03-19 2013-07-02 Monsanto Technology, Llc Homogentisate prenyl transferase ("hpt") nucleic acids and polypeptides, and uses thereof
CN1681928A (zh) 2002-08-05 2005-10-12 孟山都技术公司 生育酚生物合成相关基因及其用途
WO2004044173A2 (en) * 2002-11-13 2004-05-27 E.I. Du Pont De Nemours And Company Cis-prenyltransferases from the rubber-producing plants russian dandelion (taraxacum kok-saghyz) and sunflower (helianthus annus)
EP2500437B1 (en) * 2003-01-21 2016-11-30 PTC Therapeutics, Inc. Methods for identifying compounds that modulate untranslated region-dependent gene expression and methods of using same
US8426194B2 (en) 2003-01-21 2013-04-23 Ptc Therapeutics, Inc. Methods and agents for screening for compounds capable of modulating VEGF expression
US9068234B2 (en) * 2003-01-21 2015-06-30 Ptc Therapeutics, Inc. Methods and agents for screening for compounds capable of modulating gene expression
WO2004106531A1 (en) * 2003-05-22 2004-12-09 E.I. Dupont De Nemours And Company Method for manipulating growth, yield, and architecture in plants
CA2546363A1 (en) * 2003-11-17 2005-06-02 Anuradha Mehta Methods and agents for screening for compounds capable of modulating her2 expression
US9018449B2 (en) * 2004-03-10 2015-04-28 The United States of America, represented by The Secretary of Agiculture Transformation methods for Guayule using Agrobacterium and reduced light to slow metabolism and enhance recovery
MXPA06013502A (es) 2004-05-21 2007-03-01 Univ California Metodo para mejorar la produccion de compuestos isoprenoides.
US8828684B2 (en) 2004-07-27 2014-09-09 The Regents Of The University Of California Genetically modified host cells and use of same for producing isoprenoid compounds
PT1919514E (pt) 2005-07-05 2012-08-16 Univ California Polinucleótidos que codificam enzimas de modificação de isoprenóides e métodos de utilização destes
US20090288226A1 (en) * 2005-11-21 2009-11-19 Hallahan David L Method for manipulating growth, yield, and architecture in plants
US8257957B2 (en) 2006-09-26 2012-09-04 The Regents Of The University Of California Production of isoprenoids and isoprenoid precursors
US8283115B1 (en) 2007-06-20 2012-10-09 Ptc Therapeutics, Inc. Methods of screening for compounds for treating muscular dystrophy using UTRN mRNA translation regulation
US8283116B1 (en) 2007-06-22 2012-10-09 Ptc Therapeutics, Inc. Methods of screening for compounds for treating spinal muscular atrophy using SMN mRNA translation regulation
CA2718469C (en) 2008-03-17 2017-07-04 National Research Council Of Canada Aromatic prenyltransferase from hop
US20090253174A1 (en) * 2008-04-08 2009-10-08 Zach Serber Expression of Heterologous Sequences
BRPI0911305B1 (pt) 2008-04-14 2019-07-16 Bridgestone Corporation Processos para recuperar borracha a partir de látex de borracha natural
CA2775093A1 (en) 2009-10-02 2011-04-07 Pioneer Hi-Bred International, Inc. Down-regulation of acc synthase for improved plant performance
WO2012148835A1 (en) 2011-04-29 2012-11-01 Pioneer Hi-Bred International, Inc. Down-regulation of a homeodomain-leucine zipper i-class homeobox gene for improved plant performance
MY174987A (en) * 2011-04-29 2020-05-31 Univ Sains Malaysia Undecaprenyl pyrophosphate synthase from the plant of hevea brasiliensis
MY160195A (en) * 2011-05-12 2017-02-28 Univ Sains Malaysia Cis-prenyl transferase from the plant hevea brasiliensis
EP3216809B1 (en) 2012-03-06 2018-11-14 Bridgestone Corporation Processes for recovering rubber from aged briquettes and aged briquettes containing plant matter from non-hevea plants
RU2637956C2 (ru) 2012-05-16 2017-12-08 Бриджстоун Корпорейшн Композиции, содержащие полученный не из гевеи очищенный каучук, и соответствующие способы очистки
CN107973867B (zh) 2012-06-18 2020-06-19 株式会社普利司通 用于增加非三叶胶植物物质的可提取橡胶含量的方法
WO2013192182A1 (en) 2012-06-18 2013-12-27 Bridgestone Corporation Systems and methods for the management of waste associated with processing guayule shrubs to extract rubber
EP2861655B1 (en) 2012-06-18 2019-05-08 Bridgestone Corporation Method for desolventization of bagasse
WO2015038707A1 (en) 2013-09-11 2015-03-19 Bridgestone Corporation Processes for the removal of rubber from tks plant matter
EP3323894B1 (en) * 2015-06-15 2020-03-11 Ajou University Industry-Academic Cooperation Foundation Method for producing natural rubber by using recombinant microorganism
US9585867B2 (en) 2015-08-06 2017-03-07 Charles Everett Ankner Cannabinod formulation for the sedation of a human or animal
US10775105B2 (en) 2018-11-19 2020-09-15 Bridgestone Corporation Methods for the desolventization of bagasse

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US6316695B1 (en) 1999-04-22 2001-11-13 Korea Kumho Petrochemical Co., Ltd. Isopentenyl diphosphate isomerase from Hevea brasiliensis and rubber producing method using the same

Also Published As

Publication number Publication date
KR20020040810A (ko) 2002-05-30
CA2381020A1 (en) 2001-03-29
EP1214338A2 (en) 2002-06-19
US7273737B2 (en) 2007-09-25
AU7598200A (en) 2001-04-24
US20040152158A1 (en) 2004-08-05
US20080096276A1 (en) 2008-04-24
US6645747B1 (en) 2003-11-11
US7880058B2 (en) 2011-02-01
WO2001021650A2 (en) 2001-03-29
WO2001021650A3 (en) 2001-12-13

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