BR0013844A - Restauração de telÈmero e extensão de perìodo de vida da célula em animais clonados de células somáticas senescentes - Google Patents
Restauração de telÈmero e extensão de perìodo de vida da célula em animais clonados de células somáticas senescentesInfo
- Publication number
- BR0013844A BR0013844A BR0013844-4A BR0013844A BR0013844A BR 0013844 A BR0013844 A BR 0013844A BR 0013844 A BR0013844 A BR 0013844A BR 0013844 A BR0013844 A BR 0013844A
- Authority
- BR
- Brazil
- Prior art keywords
- cloned
- cell
- animals
- methods
- restoration
- Prior art date
Links
- 210000001082 somatic cell Anatomy 0.000 title abstract 6
- 241001465754 Metazoa Species 0.000 title abstract 4
- 210000004027 cell Anatomy 0.000 title abstract 4
- 238000000034 method Methods 0.000 abstract 4
- 101001073422 Homo sapiens Pigment epithelium-derived factor Proteins 0.000 abstract 1
- 241000124008 Mammalia Species 0.000 abstract 1
- 102100035846 Pigment epithelium-derived factor Human genes 0.000 abstract 1
- 108010017842 Telomerase Proteins 0.000 abstract 1
- 230000003213 activating effect Effects 0.000 abstract 1
- 230000032677 cell aging Effects 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 230000037361 pathway Effects 0.000 abstract 1
- 230000002062 proliferating effect Effects 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 230000003716 rejuvenation Effects 0.000 abstract 1
- 238000002054 transplantation Methods 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61P17/00—Drugs for dermatological disorders
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/14—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2517/00—Cells related to new breeds of animals
- C12N2517/04—Cells produced using nuclear transfer
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Rheumatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Diabetes (AREA)
- Cardiology (AREA)
- Immunology (AREA)
- Heart & Thoracic Surgery (AREA)
- Endocrinology (AREA)
- Urology & Nephrology (AREA)
- Reproductive Health (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Psychology (AREA)
- Pain & Pain Management (AREA)
- Genetics & Genomics (AREA)
- Virology (AREA)
- Biotechnology (AREA)
- Emergency Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Obesity (AREA)
- Hematology (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US15234099P | 1999-09-07 | 1999-09-07 | |
| US17948600P | 2000-02-01 | 2000-02-01 | |
| US52702600A | 2000-03-16 | 2000-03-16 | |
| US52087900A | 2000-04-05 | 2000-04-05 | |
| PCT/US2000/024393 WO2001018236A1 (en) | 1999-09-07 | 2000-09-06 | Telomere restoration and extension of cell life-span in animals cloned from senescent somatic cells |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR0013844A true BR0013844A (pt) | 2002-05-14 |
Family
ID=27496015
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR0013844-4A BR0013844A (pt) | 1999-09-07 | 2000-09-06 | Restauração de telÈmero e extensão de perìodo de vida da célula em animais clonados de células somáticas senescentes |
Country Status (10)
| Country | Link |
|---|---|
| EP (1) | EP1214443A4 (enExample) |
| JP (1) | JP2003508079A (enExample) |
| CN (1) | CN1377424A (enExample) |
| AU (1) | AU7350800A (enExample) |
| BR (1) | BR0013844A (enExample) |
| CA (1) | CA2383790C (enExample) |
| IL (2) | IL148457A0 (enExample) |
| MX (1) | MXPA02002443A (enExample) |
| NZ (1) | NZ531844A (enExample) |
| WO (1) | WO2001018236A1 (enExample) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL148418A0 (en) * | 1999-09-07 | 2002-09-12 | Advanced Cell Tech Inc | Method for generating immune-compatible cells and tissues using nuclear transfer techniques |
| US7713728B2 (en) | 2007-01-08 | 2010-05-11 | The Invention Sciencefund I, Llc | Systems for genome selection |
| US7947455B2 (en) | 2007-01-08 | 2011-05-24 | The Invention Science Fund I, Llc | System for genome selection |
| US7985578B2 (en) | 2007-01-08 | 2011-07-26 | The Invention Science Fund I, Llc | Systems for genome selection |
| US7718418B2 (en) | 2007-01-08 | 2010-05-18 | The Invention Science Fund I, Llc | Systems for genome selection |
| US7709244B2 (en) | 2007-01-08 | 2010-05-04 | The Invention Science Fund I, Llc | Systems for genome selection |
| US7648823B2 (en) | 2007-01-08 | 2010-01-19 | Searete Llc | Systems for genome selection |
| US7888036B2 (en) | 2007-01-08 | 2011-02-15 | The Invention Science Fund I, Llc | Systems for genome selection |
| US7947457B2 (en) | 2007-01-08 | 2011-05-24 | The Invention Science Fund I, Llc | Systems for genome selection |
| US8521440B2 (en) | 2007-01-08 | 2013-08-27 | The Invention Science Fund I, Llc | Systems for genome selection |
| US7709245B2 (en) | 2007-01-08 | 2010-05-04 | The Invention Science Fund I, Llc | Systems for genome selection |
| US8012740B2 (en) | 2007-01-08 | 2011-09-06 | The Invention Science Fund I, Llc | Systems for genome selection |
| US20110086424A1 (en) * | 2008-05-06 | 2011-04-14 | Advanced Cell Technology, Inc. | Methods for producing enucleated erythroid cells derived from pluripotent stem cells |
| JP5888852B2 (ja) * | 2010-12-08 | 2016-03-22 | 学校法人近畿大学 | 免疫不全動物を用いた細胞の製法 |
| WO2012136841A1 (en) * | 2011-04-08 | 2012-10-11 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Method for rejuvenating cells |
| EP2968392B1 (en) | 2013-03-15 | 2020-08-05 | Elixirgen Therapeutics, Inc. | Methods of using zscan4 for rejuvenating human cells |
| EP3869195B1 (en) | 2015-03-23 | 2024-03-20 | Astellas Institute for Regenerative Medicine | Improved assays for potency of human retinal pigment epithelium (rpe) cells and photoreceptor progenitors |
| AU2019333905B2 (en) * | 2018-09-06 | 2025-12-11 | The Board Of Regents Of The University Of Texas System | Telomerase holoenzyme complex and methods of use thereof |
| EP4525895A4 (en) * | 2022-05-17 | 2026-05-13 | Nat Univ Singapore | Somatic cell therapy to treat female infertility |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5648215A (en) * | 1992-05-13 | 1997-07-15 | Board Of Regents, The University Of Texas System | Telomerase diagnostic methods |
| US5489508A (en) * | 1992-05-13 | 1996-02-06 | University Of Texas System Board Of Regents | Therapy and diagnosis of conditions related to telomere length and/or telomerase activity |
| US5945577A (en) * | 1997-01-10 | 1999-08-31 | University Of Massachusetts As Represented By Its Amherst Campus | Cloning using donor nuclei from proliferating somatic cells |
| NZ337495A (en) * | 1997-03-06 | 2001-06-29 | Infigen Inc | Bovine primordial germ cells and their use in cloning |
| GB9809178D0 (en) * | 1998-04-29 | 1998-07-01 | Univ Edinburgh | Nuclear reprogramming of somatic cells |
| WO2001000650A1 (en) * | 1999-06-30 | 2001-01-04 | Advanced Cell Technology, Inc. | Cytoplasmic transfer to de-differentiate recipient cells |
| IL148418A0 (en) * | 1999-09-07 | 2002-09-12 | Advanced Cell Tech Inc | Method for generating immune-compatible cells and tissues using nuclear transfer techniques |
-
2000
- 2000-09-06 CA CA2383790A patent/CA2383790C/en not_active Expired - Lifetime
- 2000-09-06 AU AU73508/00A patent/AU7350800A/en not_active Abandoned
- 2000-09-06 JP JP2001521771A patent/JP2003508079A/ja active Pending
- 2000-09-06 NZ NZ531844A patent/NZ531844A/en not_active IP Right Cessation
- 2000-09-06 EP EP00961569A patent/EP1214443A4/en not_active Ceased
- 2000-09-06 IL IL14845700A patent/IL148457A0/xx unknown
- 2000-09-06 BR BR0013844-4A patent/BR0013844A/pt not_active Application Discontinuation
- 2000-09-06 WO PCT/US2000/024393 patent/WO2001018236A1/en not_active Ceased
- 2000-09-06 MX MXPA02002443A patent/MXPA02002443A/es not_active Application Discontinuation
- 2000-09-06 CN CN00813712A patent/CN1377424A/zh active Pending
-
2002
- 2002-02-28 IL IL148457A patent/IL148457A/en active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| CN1377424A (zh) | 2002-10-30 |
| WO2001018236A1 (en) | 2001-03-15 |
| IL148457A (en) | 2013-01-31 |
| JP2003508079A (ja) | 2003-03-04 |
| NZ531844A (en) | 2005-08-26 |
| AU7350800A (en) | 2001-04-10 |
| CA2383790C (en) | 2016-11-22 |
| MXPA02002443A (es) | 2004-07-16 |
| CA2383790A1 (en) | 2001-03-15 |
| IL148457A0 (en) | 2002-09-12 |
| EP1214443A4 (en) | 2003-08-27 |
| EP1214443A1 (en) | 2002-06-19 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
| B09B | Patent application refused [chapter 9.2 patent gazette] |
Free format text: INDEFIRO O PEDIDO DE ACORDO COM O(S) ARTIGO(S) 22 DA LPI. |
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| B09B | Patent application refused [chapter 9.2 patent gazette] |
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