BR0012528A - Cobertura aperfeiçoada para feridas para melhorar a cicatrização de feridas - Google Patents

Cobertura aperfeiçoada para feridas para melhorar a cicatrização de feridas

Info

Publication number
BR0012528A
BR0012528A BR0012528-8A BR0012528A BR0012528A BR 0012528 A BR0012528 A BR 0012528A BR 0012528 A BR0012528 A BR 0012528A BR 0012528 A BR0012528 A BR 0012528A
Authority
BR
Brazil
Prior art keywords
wound
improve
improved
enhanced
coverage
Prior art date
Application number
BR0012528-8A
Other languages
English (en)
Inventor
David N Herndon
Jose R Perez-Polo
Robert E Barrow
Original Assignee
Res Dev Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Res Dev Foundation filed Critical Res Dev Foundation
Publication of BR0012528A publication Critical patent/BR0012528A/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Liposomes
    • A61K9/1271Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers
    • A61K9/1272Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers with substantial amounts of non-phosphatidyl, i.e. non-acylglycerophosphate, surfactants as bilayer-forming substances, e.g. cationic lipids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/30Insulin-like growth factors, i.e. somatomedins, e.g. IGF-1, IGF-2
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/22Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
    • A61L15/32Proteins, polypeptides; Degradation products or derivatives thereof, e.g. albumin, collagen, fibrin, gelatin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/40Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing ingredients of undetermined constitution or reaction products thereof, e.g. plant or animal extracts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0009Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
    • A61L26/0028Polypeptides; Proteins; Degradation products thereof
    • A61L26/0047Specific proteins or polypeptides not covered by groups A61L26/0033 - A61L26/0042
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Materials Engineering (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Zoology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • Endocrinology (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Botany (AREA)
  • Diabetes (AREA)
  • Dispersion Chemistry (AREA)
  • Biophysics (AREA)
  • Dermatology (AREA)
  • Surgery (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

Patente de Invenção: "COBERTURA APERFEIçOADA PARA FERIDAS PARA MELHORAR A CICATRIZAçãO DE FERIDAS". A presente invenção descreve a incorporação de construções de gene lipossomal diretamente em uma ferida para melhorar ainda mais o reparo da ferida ou em materiais para cobertura e/ou fechamento de feridas para melhorar a funcionalidade do material. A presente invenção também descreve o uso de membranas fetais humanas (por exemplo, âmnio) aperfeiçoadas com a terapia de gene lipossomal como um material de cobertura de ferida em reparo de ferida em espessura completa. As membranas fetais aperfeiçoadas ou pele de cadáver aperfeiçoada têm vantagens em relação aos materiais normalmente usados em que falta a construção do gene lipossomal e são uma abordagem eficiente e segura para melhorar resultado clínico em pacientes com ferimentos por queimadura.
BR0012528-8A 1999-06-22 2000-06-22 Cobertura aperfeiçoada para feridas para melhorar a cicatrização de feridas BR0012528A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US14019699P 1999-06-22 1999-06-22
PCT/US2000/017186 WO2000078259A1 (en) 1999-06-22 2000-06-22 Enhanced wound coverage to enhance wound healing

Publications (1)

Publication Number Publication Date
BR0012528A true BR0012528A (pt) 2002-04-09

Family

ID=22490162

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0012528-8A BR0012528A (pt) 1999-06-22 2000-06-22 Cobertura aperfeiçoada para feridas para melhorar a cicatrização de feridas

Country Status (12)

Country Link
US (2) US6576618B1 (pt)
EP (1) EP1210046A4 (pt)
JP (1) JP2003502350A (pt)
CN (1) CN1137723C (pt)
AU (1) AU771904B2 (pt)
BR (1) BR0012528A (pt)
CA (1) CA2377371A1 (pt)
IL (1) IL147127A0 (pt)
MX (1) MXPA02000128A (pt)
RU (1) RU2245722C2 (pt)
WO (1) WO2000078259A1 (pt)
ZA (1) ZA200110240B (pt)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000078259A1 (en) * 1999-06-22 2000-12-28 Research Development Foundation Enhanced wound coverage to enhance wound healing
WO2002089854A1 (fr) * 2001-05-09 2002-11-14 Anges Mg, Inc. Transfert de genes et facteur angiogenique pour maladie de la peau
DE10214260A1 (de) * 2002-03-30 2003-10-23 Wolfgang Richter Liposomaler Polynucleotidsequenzkomplex zur topischen Applikation auf Körperoberflächen oder systemischen Verabreichung für die medizinische oder kosmetische Anwendung
JP4728807B2 (ja) * 2003-09-03 2011-07-20 敏一 中村 ヒト組換えhgfを含有する皮膚潰瘍予防治癒剤
GB2423934B (en) * 2003-09-04 2007-11-28 Cook Biotech Inc Extracellular matrix composite materials, and manufacture and use thereof
US8276091B2 (en) * 2003-09-16 2012-09-25 Ram Consulting Haptic response system and method of use
ATE513823T1 (de) * 2004-08-17 2011-07-15 Simpson Biotech Co Ltd Mischung und verbindungen von mycelien von antrodia camphorata und deren verwendung
US8454678B2 (en) * 2005-03-19 2013-06-04 Cook Biotech Incorporated Prosthetic implants including ECM composite material
CN103356703B (zh) * 2005-03-31 2016-04-06 斯丹姆涅恩有限公司 制备用以治疗慢性感染伤口的药物的方法
CN1853609B (zh) * 2005-04-25 2010-05-12 邱英明 酸性纤维母细胞生长因子(fgf-1)应用于护肤功效
US8778362B2 (en) 2005-10-27 2014-07-15 University Of Notre Dame Anti-tumor/cancer heterologous acellular collagenous preparations and uses thereof
GB0611405D0 (en) 2006-06-09 2006-07-19 Univ Belfast FKBP-L: A novel inhibitor of angiogenesis
US8372437B2 (en) 2006-08-17 2013-02-12 Mimedx Group, Inc. Placental tissue grafts
CA2667214C (en) * 2006-10-23 2015-12-01 Cook Biotech Incorporated Processed ecm materials with enhanced component profiles
JP2010528613A (ja) 2007-05-29 2010-08-26 クリストファー ビー. リード, 多能細胞集団を産生する方法およびその使用
CA2736663C (en) 2007-09-07 2018-01-02 Surgical Biologics, Llc. Placental tissue grafts and improved methods of preparing and using the same
US10500309B2 (en) * 2007-10-05 2019-12-10 Cook Biotech Incorporated Absorbable adhesives and their formulation for use in medical applications
US20100008965A1 (en) * 2008-04-01 2010-01-14 Pavalko Fredrick M Biocompatible medical products having enhanced anti-thrombogenic properties
US9358320B2 (en) 2008-04-25 2016-06-07 Allosource Multi-layer tissue patches
US9480549B2 (en) 2008-04-25 2016-11-01 Allosource Multi-layer tissue patches
KR20110013419A (ko) * 2008-04-25 2011-02-09 알로소스 가공된 양막 조직을 포함하는 유착 방지 배리어 상처 드레싱 및 이를 사용하는 방법
JP2011526811A (ja) 2008-07-01 2011-10-20 クック・バイオテック・インコーポレイテッド 漿膜下筋膜を含む分離された細胞外マトリクス材料
EP2454368A4 (en) 2009-07-17 2013-01-09 Aaron Thomas Tabor COMPOSITIONS AND METHOD FOR THE GENETIC MODIFICATION OF COSMETIC FUNCTION CELLS FOR IMPROVING THE COSMETIC APPEARANCE PICTURE
WO2011031827A2 (en) 2009-09-09 2011-03-17 Cook Biotech Incorporated Manufacture of extracellular matrix products using supercritical or near supercritical fluids
US10279007B2 (en) 2010-11-15 2019-05-07 Oxygenetix Institute, Inc. Topical treatment method for healing wounds, disinfecting, covering and concealing the wound until healing occurs
JP6448615B2 (ja) 2013-03-15 2019-01-09 クック・バイオテック・インコーポレイテッドCook Biotech Incorporated Ecm移植組成物および方法
CN105536031B (zh) * 2016-02-03 2018-12-11 浙江康诚工业产品设计有限公司 一种茶树油脂质体抗炎抑菌医用敷料的制备方法
CA3187505A1 (en) 2020-07-27 2022-02-03 Loran Solorio Adhesive for surgical staple line reinforcement

Family Cites Families (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4361552A (en) * 1980-09-26 1982-11-30 Board Of Regents, The University Of Texas System Wound dressing
DE3587022T2 (de) * 1984-02-17 1993-06-17 Genentech Inc Menschlicher transformationswachstumsfaktor und vorlaeufer oder fragment hiervon, zellen, dna, vektoren und verfahren zu ihrer herstellung, zusammensetzungen und produkte, die diese enthalten, sowie davon abgeleitete antikoerper und diagnostizierverfahren.
US4897355A (en) * 1985-01-07 1990-01-30 Syntex (U.S.A.) Inc. N[ω,(ω-1)-dialkyloxy]- and N-[ω,(ω-1)-dialkenyloxy]-alk-1-yl-N,N,N-tetrasubstituted ammonium lipids and uses therefor
GB8708009D0 (en) * 1987-04-03 1987-05-07 Clayton Found Res Injectable soft tissue augmentation materials
US5976878A (en) * 1987-04-28 1999-11-02 The Regents Of The University Of California Method and apparatus for preparing composite skin replacement
NZ226170A (en) * 1987-09-18 1990-07-26 Ethicon Inc Stable freeze-dried pharmaceutical composition containing epidermal growth factor
US5256644A (en) * 1988-05-20 1993-10-26 Institute Of Molecular Biology, Inc. Wound healing using IGF-II and TGF
US5064655A (en) * 1989-02-24 1991-11-12 Liposome Technology, Inc. Liposome gel composition and method
US6559119B1 (en) * 1990-11-27 2003-05-06 Loyola University Of Chicago Method of preparing a tissue sealant-treated biomedical material
ATE148994T1 (de) * 1990-12-04 1997-03-15 Zenith Technology Corp Ltd Kunsthaut
US5265644A (en) * 1992-06-02 1993-11-30 Walbro Corporation Fuel pressure regulator
ES2107668T3 (es) * 1992-07-08 1997-12-01 Dianorm G Maierhofer Gmbh Liposomas, procedimiento para su preparacion y su uso en la elaboracion de un medicamento.
ATE241340T1 (de) * 1994-02-17 2003-06-15 New York Blood Ct Inc Biologische bioadhäsive präparate, die fibrinkleber und liposomen enthalten, verfahren für ihre herstellung und verwendung
US5962427A (en) * 1994-02-18 1999-10-05 The Regent Of The University Of Michigan In vivo gene transfer methods for wound healing
US5728546A (en) * 1995-06-05 1998-03-17 Human Genome Sciences, Inc. Fibroblast growth factor 13
US6139819A (en) * 1995-06-07 2000-10-31 Imarx Pharmaceutical Corp. Targeted contrast agents for diagnostic and therapeutic use
ES2240999T3 (es) * 1995-08-29 2005-10-16 Anges Mg, Inc. Medicamento que contiene un gen del hgf.
US6132765A (en) * 1996-04-12 2000-10-17 Uroteq Inc. Drug delivery via therapeutic hydrogels
US6143037A (en) * 1996-06-12 2000-11-07 The Regents Of The University Of Michigan Compositions and methods for coating medical devices
US6252129B1 (en) * 1996-07-23 2001-06-26 Electrosols, Ltd. Dispensing device and method for forming material
US5741509A (en) * 1996-08-26 1998-04-21 Alvin S. Berlat Silicone wound dressing
US6153631A (en) * 1996-10-23 2000-11-28 Zymogenetics, Inc. Compositions and methods for treating bone deficit conditions
DE69731660T2 (de) * 1996-12-02 2005-12-22 Valentis Inc., Burlingame Insulinähnlicher wachstumfaktor i (igf-i) expressionssystem und methode zur verwendung
US6034072A (en) * 1997-02-10 2000-03-07 Genemedicine, Inc. IL-2 gene expression and delivery systems and uses
US5837283A (en) * 1997-03-12 1998-11-17 The Regents Of The University Of California Cationic lipid compositions targeting angiogenic endothelial cells
EP1027033B1 (en) * 1997-05-14 2009-07-22 The University Of British Columbia High efficiency encapsulation of nucleic acids in lipid vesicles
US6060590A (en) * 1998-03-31 2000-05-09 The Regents Of The University Of California Chitinase related proteins and methods of use
CN1379681A (zh) * 1998-04-17 2002-11-13 安乔格尼克斯公司 治疗性的血管生成因子及其使用方法
US20010056073A1 (en) * 1998-07-21 2001-12-27 Ascher Shmulewitz Gene therapy method for revascularizing ischemic tissue
WO2000078259A1 (en) * 1999-06-22 2000-12-28 Research Development Foundation Enhanced wound coverage to enhance wound healing

Also Published As

Publication number Publication date
JP2003502350A (ja) 2003-01-21
EP1210046A4 (en) 2007-05-02
CA2377371A1 (en) 2000-12-28
IL147127A0 (en) 2002-08-14
RU2245722C2 (ru) 2005-02-10
CN1137723C (zh) 2004-02-11
AU771904B2 (en) 2004-04-08
AU5758500A (en) 2001-01-09
WO2000078259A1 (en) 2000-12-28
ZA200110240B (en) 2003-05-28
EP1210046A1 (en) 2002-06-05
MXPA02000128A (es) 2002-06-21
CN1372450A (zh) 2002-10-02
US6576618B1 (en) 2003-06-10
US20020128222A1 (en) 2002-09-12

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Legal Events

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B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 9A E 10A ANUIDADE(S).

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2108 DE 31/05/2011.