BG62349B2 - N-заместени производни на 3-азабицикло/3.2.0/хептан като невролептици - Google Patents

N-заместени производни на 3-азабицикло/3.2.0/хептан като невролептици Download PDF

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Publication number
BG62349B2
BG62349B2 BG98601A BG9860194A BG62349B2 BG 62349 B2 BG62349 B2 BG 62349B2 BG 98601 A BG98601 A BG 98601A BG 9860194 A BG9860194 A BG 9860194A BG 62349 B2 BG62349 B2 BG 62349B2
Authority
BG
Bulgaria
Prior art keywords
azabicyclo
exo
heptan
fluorophenyl
heptane
Prior art date
Application number
BG98601A
Other languages
Bulgarian (bg)
English (en)
Inventor
Gerd Steiner
Liliane Unger
Berthold Behl
Hans-Juergen Teschendorf
Original Assignee
Basf Aktiengesellschaft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basf Aktiengesellschaft filed Critical Basf Aktiengesellschaft
Publication of BG62349B2 publication Critical patent/BG62349B2/bg

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/52—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring condensed with a ring other than six-membered
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
BG98601A 1992-06-19 1994-02-28 N-заместени производни на 3-азабицикло/3.2.0/хептан като невролептици BG62349B2 (bg)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4219973A DE4219973A1 (de) 1992-06-19 1992-06-19 N-substituierte Azabicycloheptan-Derivate, ihre Herstellung und Verwendung

Publications (1)

Publication Number Publication Date
BG62349B2 true BG62349B2 (bg) 1999-08-31

Family

ID=6461299

Family Applications (1)

Application Number Title Priority Date Filing Date
BG98601A BG62349B2 (bg) 1992-06-19 1994-02-28 N-заместени производни на 3-азабицикло/3.2.0/хептан като невролептици

Country Status (14)

Country Link
US (1) US5521209A (zh)
EP (1) EP0646110B1 (zh)
JP (1) JP3171261B2 (zh)
AT (1) ATE144497T1 (zh)
BG (1) BG62349B2 (zh)
CA (1) CA2138287C (zh)
DE (2) DE4219973A1 (zh)
DK (1) DK0646110T3 (zh)
ES (1) ES2094545T3 (zh)
GR (1) GR3021736T3 (zh)
MX (1) MX9303605A (zh)
SG (1) SG82540A1 (zh)
TW (1) TW261614B (zh)
WO (1) WO1994000431A1 (zh)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5527910A (en) * 1992-12-30 1996-06-18 Cheil Foods & Chemicals, Inc. Pyridone carboxylic acid compounds and their uses for treating infectious diseases caused by bacteria
DE4341402A1 (de) * 1993-12-04 1995-06-08 Basf Ag N-substituierte Azabicycloheptan-Derivate, ihre Herstellung und Verwendung
DE4341403A1 (de) * 1993-12-04 1995-06-08 Basf Ag N-substituierte 3-Azabicycloalkan-Derivate, ihre Herstellung und Verwendung
DE4427647A1 (de) * 1994-08-04 1996-02-08 Basf Ag N-substituierte Azabicycloheptan-Derivate, ihre Herstellung und Verwendung
EP1098897B1 (en) 1998-07-17 2004-06-09 Agouron Pharmaceuticals, Inc. Compounds, compositions, and methods for stimulating neuronal growth and elongation
DE19836404A1 (de) * 1998-08-12 2000-02-17 Basf Ag N-Substituierte Azabicycloheptan-Derivate, ihre Herstellung und Verwendung
DE19836406A1 (de) 1998-08-12 2000-02-17 Basf Ag N-Substituierte Azabicycloheptan-Derivate, ihre Herstellung und Verwendung
US6458821B1 (en) 1998-08-12 2002-10-01 Abbott Laboratories N-substituted azabicycloheptane derivatives, production and use thereof
DE19848521A1 (de) * 1998-10-21 2000-04-27 Basf Ag Verfahren zur Herstellung von (+)-exo-6-Phenyl-3-azabicyclo-[3.2.0]heptanen
ATE520659T1 (de) * 2004-10-14 2011-09-15 Abbott Gmbh & Co Kg Zur behandlung von auf die modulation des dopamin-d3-rezeptors ansprechenden erkrankungen geeignete azabicycloheptylverbindungen

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL110185C (zh) * 1958-04-22
US3328390A (en) * 1962-02-27 1967-06-27 Tri Kem Corp Certain azabicycloalkane compounds
NO154582C (no) * 1978-10-20 1986-11-05 Ferrosan Ab Analogifremgangsmaate for fremstilling av terapeutisk aktive difenyl-dibutylpiperazinkarboksamider.
US4605655A (en) * 1984-03-06 1986-08-12 Bristol-Myers Company Antipsychotic 1-fluorophenylbutyl-4-(2-pyrimidinyl)piperazine derivatives
DE3571436D1 (en) * 1984-12-21 1989-08-17 Duphar Int Res New pharmaceutical compositions having anti-psychotic properties
US5055470A (en) * 1989-06-01 1991-10-08 Bristol-Myers Squibb Co. Method of treatment of ischemia in brain
US4994460A (en) * 1989-06-01 1991-02-19 Bristol-Myers Squibb Co. Agents for treatment of brain ischemia
DE4112353A1 (de) * 1991-04-16 1992-10-22 Basf Ag 1,3,4-trisubstituierte piperidin-derivate, ihre herstellung und verwendung

Also Published As

Publication number Publication date
CA2138287A1 (en) 1994-01-06
TW261614B (zh) 1995-11-01
DE4219973A1 (de) 1993-12-23
WO1994000431A1 (de) 1994-01-06
JPH07508012A (ja) 1995-09-07
CA2138287C (en) 2005-03-01
GR3021736T3 (en) 1997-02-28
EP0646110B1 (de) 1996-10-23
ES2094545T3 (es) 1997-01-16
EP0646110A1 (de) 1995-04-05
ATE144497T1 (de) 1996-11-15
DE59304311D1 (de) 1996-11-28
DK0646110T3 (da) 1996-11-18
US5521209A (en) 1996-05-28
SG82540A1 (en) 2001-08-21
JP3171261B2 (ja) 2001-05-28
MX9303605A (es) 1993-12-01

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